Aliases for EGFL6 Gene
External Ids for EGFL6 Gene
Previous HGNC Symbols for EGFL6 Gene
Previous GeneCards Identifiers for EGFL6 Gene
This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008]
GeneCards Summary for EGFL6 Gene
EGFL6 (EGF Like Domain Multiple 6) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding and integrin binding. An important paralog of this gene is NPNT.
UniProtKB/Swiss-Prot for EGFL6 Gene
May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity).