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Aliases for EFCAB7 Gene

Aliases for EFCAB7 Gene

  • EF-Hand Calcium Binding Domain 7 2 3
  • KIAA1799 4

External Ids for EFCAB7 Gene

Summaries for EFCAB7 Gene

GeneCards Summary for EFCAB7 Gene

EFCAB7 (EF-Hand Calcium Binding Domain 7) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EFCAB7 Gene

Genomics for EFCAB7 Gene

Genomic Location for EFCAB7 Gene

Start:
63,523,342 bp from pter
End:
63,585,370 bp from pter
Size:
62,029 bases
Orientation:
Plus strand

Genomic View for EFCAB7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for EFCAB7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EFCAB7 Gene

Regulatory Elements for EFCAB7 Gene

Proteins for EFCAB7 Gene

  • Protein details for EFCAB7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8K855-EFCB7_HUMAN
    Recommended name:
    EF-hand calcium-binding domain-containing protein 7
    Protein Accession:
    A8K855
    Secondary Accessions:
    • Q658P0
    • Q96B95
    • Q96JM6

    Protein attributes for EFCAB7 Gene

    Size:
    629 amino acids
    Molecular mass:
    71981 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB47428.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for EFCAB7 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for EFCAB7 Gene

Proteomics data for EFCAB7 Gene at MOPED

Post-translational modifications for EFCAB7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for EFCAB7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for EFCAB7 Gene

Domains for EFCAB7 Gene

Gene Families for EFCAB7 Gene

HGNC:
  • EFHAND :EF-hand domain containing

Protein Domains for EFCAB7 Gene

UniProtKB/Swiss-Prot:

EFCB7_HUMAN
Domain:
  • Contains 3 EF-hand domains.:
    • A8K855
genes like me logo Genes that share domains with EFCAB7: view

Function for EFCAB7 Gene

Gene Ontology (GO) - Molecular Function for EFCAB7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005509 calcium ion binding IEA --
genes like me logo Genes that share ontologies with EFCAB7: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for EFCAB7 Gene

Localization for EFCAB7 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for EFCAB7 Gene COMPARTMENTS Subcellular localization image for EFCAB7 gene
Compartment Confidence
cytosol 2
nucleus 2
plasma membrane 2

Gene Ontology (GO) - Cellular Components for EFCAB7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0072372 primary cilium TAS --
genes like me logo Genes that share ontologies with EFCAB7: view

Pathways for EFCAB7 Gene

SuperPathways for EFCAB7 Gene

No Data Available

Interacting Proteins for EFCAB7 Gene

Gene Ontology (GO) - Biological Process for EFCAB7 Gene

None

No data available for Pathways by source for EFCAB7 Gene

Transcripts for EFCAB7 Gene

Unigene Clusters for EFCAB7 Gene

EF-hand calcium binding domain 7:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for EFCAB7 Gene

No ASD Table

Relevant External Links for EFCAB7 Gene

GeneLoc Exon Structure for
EFCAB7
ECgene alternative splicing isoforms for
EFCAB7

Expression for EFCAB7 Gene

mRNA expression in normal human tissues for EFCAB7 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for EFCAB7 Gene

SOURCE GeneReport for Unigene cluster for EFCAB7 Gene Hs.652324

genes like me logo Genes that share expressions with EFCAB7: view

Orthologs for EFCAB7 Gene

This gene was present in the common ancestor of animals.

Orthologs for EFCAB7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia EFCAB7 36
  • 99.52 (n)
  • 99.05 (a)
EFCAB7 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia EFCAB7 36
  • 90.83 (n)
  • 87.92 (a)
EFCAB7 37
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia EFCAB7 36
  • 92.05 (n)
  • 89.51 (a)
EFCAB7 37
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Efcab7 36
  • 85.99 (n)
  • 82.96 (a)
Efcab7 16
Efcab7 37
  • 77 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia EFCAB7 37
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 71 (a)
OneToMany
-- 37
  • 61 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Efcab7 36
  • 86.2 (n)
  • 82.96 (a)
chicken
(Gallus gallus)
Aves EFCAB7 36
  • 72.73 (n)
  • 65.87 (a)
EFCAB7 37
  • 65 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia EFCAB7 37
  • 59 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia efcab7 36
  • 67.25 (n)
  • 62.2 (a)
zebrafish
(Danio rerio)
Actinopterygii efcab7 36
  • 59.78 (n)
  • 56.33 (a)
efcab7 37
  • 55 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea T02G5.3 37
  • 20 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 40 (a)
OneToOne
Species with no ortholog for EFCAB7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for EFCAB7 Gene

ENSEMBL:
Gene Tree for EFCAB7 (if available)
TreeFam:
Gene Tree for EFCAB7 (if available)

Paralogs for EFCAB7 Gene

Selected SIMAP similar genes for EFCAB7 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with EFCAB7: view

No data available for Paralogs for EFCAB7 Gene

Variants for EFCAB7 Gene

Sequence variations from dbSNP and Humsavar for EFCAB7 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs170090 -- 63,569,476(-) CCAAC(C/T)TCTAT intron-variant
rs177763 -- 63,559,093(-) aatta(A/C)tgacc intron-variant
rs183368 -- 63,558,831(-) gagcc(A/G)agatc intron-variant
rs217446 -- 63,545,149(+) cctga(C/T)ctcat intron-variant
rs217447 -- 63,544,038(+) gatca(C/T)ggctc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for EFCAB7 Gene

Variant ID Type Subtype PubMed ID
nsv461672 CNV Gain 19166990
nsv470714 CNV Gain 18288195
nsv871689 CNV Loss 21882294
nsv870480 CNV Loss 21882294
nsv510935 CNV Complex 20534489
nsv823076 CNV Gain 20364138
nsv1143 CNV Insertion 18451855

Relevant External Links for EFCAB7 Gene

HapMap Linkage Disequilibrium report
EFCAB7

Disorders for EFCAB7 Gene

No disorders were found for EFCAB7 Gene.

No data available for UniProtKB/Swiss-Prot for EFCAB7 Gene

Publications for EFCAB7 Gene

  1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3
  4. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3
  5. Proteomic analysis reveals a FANCA-modulated neddylation pathway involved in CXCR5 membrane targeting and cell mobility. (PMID: 25015289) Renaudin X. … Rosselli F. (J. Cell. Sci. 2014) 3

Products for EFCAB7 Gene

  • antibodies-online proteins for EFCAB7
  • antibodies-online antibodies for EFCAB7
  • antibodies-online kits for EFCAB7

Sources for EFCAB7 Gene

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