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Aliases for EEF1E1-BLOC1S5 Gene

Subcategory (RNA class) for EEF1E1-BLOC1S5 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for EEF1E1-BLOC1S5 Gene

  • EEF1E1-BLOC1S5 Readthrough (NMD Candidate) 2 3 5
  • EEF1E1-MUTED Readthrough 3
  • EEF1E1-MUTED 3

External Ids for EEF1E1-BLOC1S5 Gene

Previous GeneCards Identifiers for EEF1E1-BLOC1S5 Gene

  • GC06M008018

Summaries for EEF1E1-BLOC1S5 Gene

Entrez Gene Summary for EEF1E1-BLOC1S5 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) and MUTED (muted homolog) genes on chromosome 6. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD) and is unlikely to produce a protein product. [provided by RefSeq, Dec 2010]

GeneCards Summary for EEF1E1-BLOC1S5 Gene

EEF1E1-BLOC1S5 (EEF1E1-BLOC1S5 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. An important paralog of this gene is EEF1E1.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EEF1E1-BLOC1S5 Gene

Genomics for EEF1E1-BLOC1S5 Gene

Regulatory Elements for EEF1E1-BLOC1S5 Gene

Enhancers for EEF1E1-BLOC1S5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G008099 1.4 Ensembl ENCODE 0.7 +1.1 1062 3.6 HDGF FOXA2 PKNOX1 MLX CREB3L1 ARNT ZFP64 ARID4B SIN3A DMAP1 RIOK1 ENSG00000225092 EEF1E1 EEF1E1-BLOC1S5 GC06P008087
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around EEF1E1-BLOC1S5 on UCSC Golden Path with GeneCards custom track

Promoters for EEF1E1-BLOC1S5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000192875 394 1600 HDGF FOXA2 PKNOX1 MLX CREB3L1 ARNT ZFP64 ARID4B SIN3A DMAP1

Genomic Location for EEF1E1-BLOC1S5 Gene

Chromosome:
6
Start:
8,013,567 bp from pter
End:
8,102,595 bp from pter
Size:
89,029 bases
Orientation:
Minus strand

Genomic View for EEF1E1-BLOC1S5 Gene

Genes around EEF1E1-BLOC1S5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
EEF1E1-BLOC1S5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for EEF1E1-BLOC1S5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EEF1E1-BLOC1S5 Gene

Proteins for EEF1E1-BLOC1S5 Gene

  • Protein details for EEF1E1-BLOC1S5 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    C9J1V9
    Recommended name:
    EEF1E1-BLOC1S5 readthrough (NMD candidate)
    Protein Accession:
    C9J1V9

    Protein attributes for EEF1E1-BLOC1S5 Gene

    Size:
    151 amino acids
    Molecular mass:
    17018 Da
    Quaternary structure:
    No Data Available

neXtProt entry for EEF1E1-BLOC1S5 Gene

Protein Expression for EEF1E1-BLOC1S5 Gene

Post-translational modifications for EEF1E1-BLOC1S5 Gene

No Post-translational modifications

Other Protein References for EEF1E1-BLOC1S5 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for EEF1E1-BLOC1S5 Gene

Domains & Families for EEF1E1-BLOC1S5 Gene

Protein Domains for EEF1E1-BLOC1S5 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with EEF1E1-BLOC1S5: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for EEF1E1-BLOC1S5 Gene

Function for EEF1E1-BLOC1S5 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for EEF1E1-BLOC1S5 Gene

Localization for EEF1E1-BLOC1S5 Gene

Gene Ontology (GO) - Cellular Components for EEF1E1-BLOC1S5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with EEF1E1-BLOC1S5: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for EEF1E1-BLOC1S5 Gene

Pathways & Interactions for EEF1E1-BLOC1S5 Gene

SuperPathways for EEF1E1-BLOC1S5 Gene

No Data Available

Interacting Proteins for EEF1E1-BLOC1S5 Gene

Gene Ontology (GO) - Biological Process for EEF1E1-BLOC1S5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008285 negative regulation of cell proliferation IEA --
GO:0043065 positive regulation of apoptotic process IEA --
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator IEA --
GO:2001235 positive regulation of apoptotic signaling pathway IEA --
genes like me logo Genes that share ontologies with EEF1E1-BLOC1S5: view

No data available for Pathways by source and SIGNOR curated interactions for EEF1E1-BLOC1S5 Gene

Drugs & Compounds for EEF1E1-BLOC1S5 Gene

No Compound Related Data Available

Transcripts for EEF1E1-BLOC1S5 Gene

mRNA/cDNA for EEF1E1-BLOC1S5 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for EEF1E1-BLOC1S5 Gene

No ASD Table

Relevant External Links for EEF1E1-BLOC1S5 Gene

GeneLoc Exon Structure for
EEF1E1-BLOC1S5
ECgene alternative splicing isoforms for
EEF1E1-BLOC1S5

Expression for EEF1E1-BLOC1S5 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from PaxDb and MOPED for EEF1E1-BLOC1S5 Gene



Protein tissue co-expression partners for EEF1E1-BLOC1S5 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for EEF1E1-BLOC1S5 Gene

Orthologs for EEF1E1-BLOC1S5 Gene

This gene was present in the common ancestor of animals.

Orthologs for EEF1E1-BLOC1S5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia EEF1E1 35
  • 76 (a)
OneToMany
cow
(Bos Taurus)
Mammalia EEF1E1 35
  • 74 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 74 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 66 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Eef1e1 35
  • 66 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 52 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 55 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 59 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii eef1e1 35
  • 47 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG30185 35
  • 22 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2900 35
  • 25 (a)
OneToMany
Species where no ortholog for EEF1E1-BLOC1S5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for EEF1E1-BLOC1S5 Gene

ENSEMBL:
Gene Tree for EEF1E1-BLOC1S5 (if available)
TreeFam:
Gene Tree for EEF1E1-BLOC1S5 (if available)

Paralogs for EEF1E1-BLOC1S5 Gene

Paralogs for EEF1E1-BLOC1S5 Gene

(1) SIMAP similar genes for EEF1E1-BLOC1S5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with EEF1E1-BLOC1S5: view

Variants for EEF1E1-BLOC1S5 Gene

Sequence variations from dbSNP and Humsavar for EEF1E1-BLOC1S5 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000004139 -- 8,060,950(+) TTCCC(A/G)AGTAG intron-variant
rs1000041649 -- 8,087,392(+) TTTGT(A/G)GTTTT intron-variant, upstream-variant-2KB
rs1000052198 -- 8,073,076(+) CCCCT(A/G)TTTCA intron-variant, downstream-variant-500B
rs1000123610 -- 8,045,929(+) TGCTG(A/T)AATGA intron-variant
rs1000149057 -- 8,063,996(+) CAGGG(A/G)TCCTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for EEF1E1-BLOC1S5 Gene

Variant ID Type Subtype PubMed ID
esv2662813 CNV deletion 23128226
esv2672674 CNV deletion 23128226
esv2731544 CNV deletion 23290073
esv3306258 CNV mobile element insertion 20981092
esv3356211 CNV insertion 20981092
esv3570754 CNV loss 25503493
esv3576096 CNV gain 25503493
esv3608024 CNV loss 21293372
esv3608025 CNV loss 21293372
nsv1074375 CNV deletion 25765185
nsv1109758 CNV deletion 24896259
nsv1124025 CNV deletion 24896259
nsv1133014 OTHER inversion 24896259
nsv1151332 OTHER inversion 26484159
nsv478355 CNV novel sequence insertion 20440878
nsv600924 CNV gain 21841781
nsv600927 CNV gain 21841781

Relevant External Links for EEF1E1-BLOC1S5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
EEF1E1-BLOC1S5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for EEF1E1-BLOC1S5 Gene

Disorders for EEF1E1-BLOC1S5 Gene

Relevant External Links for EEF1E1-BLOC1S5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
EEF1E1-BLOC1S5

No disorders were found for EEF1E1-BLOC1S5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for EEF1E1-BLOC1S5 Gene

Publications for EEF1E1-BLOC1S5 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 64

Products for EEF1E1-BLOC1S5 Gene

Sources for EEF1E1-BLOC1S5 Gene

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