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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

EEF1E1 Gene

protein-coding   GIFtS: 51
GCID: GC06M008024

eukaryotic translation elongation factor 1 epsilon 1


(Previous symbol: P18)
 Explore 8 diseases affiliated with
EEF1E1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for EEF1E1    

Aliases
for EEF1E1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Eukaryotic Translation Elongation Factor 1 Epsilon 11 2     ARS-Interacting Multifunctional Protein 32
AIMP31 2 3     Eukaryotic Translation Elongation Factor 1 Epsilon-12
P181 2 3     P18 Component Of Aminoacyl-TRNA Synthetase Complex2
Aminoacyl TRNA Synthetase Complex-Interacting Multifunctional Protein 32 3     Elongation Factor P183
Multisynthase Complex Auxiliary Component P182 3     

External Ids:    HGNC: 32121   Entrez Gene: 95212   Ensembl: ENSG000001248027   OMIM: 6092065   UniProtKB: O433243   

Export aliases for EEF1E1 gene to outside databases

Previous GC identifer: GC06M008064


Summaries
for EEF1E1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for EEF1E1:
This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the
encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse
homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in
ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through
transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An
EEF1E1-related pseudogene has been identified on chromosome 2. (provided by RefSeq, Dec 2010)

UniProtKB/Swiss-Prot: MCA3_HUMAN, O43324
Function: Positive modulator of ATM response to DNA damage

Gene Wiki entry for EEF1E1


Genomic Views
for EEF1E1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the EEF1E1 gene promoter:
         CREB   TBP   LHX3b/Lhx3b   Sp1   deltaCREB   TFIID   LHX3a/Lhx3a   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: EEF1E1 promoter sequence
   Search SABiosciences Chromatin IP Primers for EEF1E1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat EEF1E1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p24.3   Ensembl cytogenetic band:  6p24.3   HGNC cytogenetic band: 6p24.3

EEF1E1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
EEF1E1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M008024:  view genomic region     (about GC identifiers)

Start:
 8,073,593 bp from pter      End:
 8,102,828 bp from pter
Size:
 29,236 bases      Orientation:
 minus strand

Proteins
for EEF1E1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MCA3_HUMAN, O43324 (See protein sequence)
Recommended Name: Eukaryotic translation elongation factor 1 epsilon-1  
Size: 174 amino acids; 19811 Da
Subunit: Component of the multisynthase complex which is comprised of a bifunctional glutamyl-prolyl-tRNA synthase, the
monospecific isoleucyl, leucyl, glutaminyl, methionyl, lysyl, arginyl and aspartyl-tRNA synthases, and three auxiliary
proteins, EEF1E1/p18, AIMP2/p38 and AIMP1/p43. Interacts with ATM and ATR. The interaction with ATM, which takes place
independently of TP53, is induced by DNA damage that may occur during genotoxic stress or cell growth. The interaction
with ATR is enhanced by UV irradiation
Subcellular location: Cytoplasm. Nucleus. Note=Cytoplasmic under growth arrest conditions. Translocated into the
nucleus when growth resumes (S phase) and following DNA damage
1 PDB 3D structure from and Proteopedia for EEF1E1:
2UZ8 (3D)    
Secondary accessions: C9JLK5 Q5THS2
Alternative splicing: 2 isoforms:  O43324-1   O43324-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for EEF1E1: NX_O43324

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O43324

    • EEF1E1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001129122.1  NP_004271.1  

    ENSEMBL proteins: 
     ENSP00000414363   ENSP00000427572   ENSP00000369038   ENSP00000424222   ENSP00000427143  
     ENSP00000425577  
    Reactome Protein details: O43324
    Human Recombinant Protein Products: 
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    Novus Biologicals EEF1E1 Lysates
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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm ISS--
    GO:0005829cytosol TAS--


    EEF1E1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for EEF1E1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    EEF1E1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR004046 GST_C
     IPR017933 Glutathione_S_Trfase/Cl_chnl_C
     IPR010987 Glutathione-S-Trfase_C-like

    Graphical View of Domain Structure for InterPro Entry O43324

    ProtoNet protein and cluster: O43324

    UniProtKB/Swiss-Prot: MCA3_HUMAN, O43324
    Similarity: Contains 1 GST C-terminal domain


    Function
    for EEF1E1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: MCA3_HUMAN, O43324
    Function: Positive modulator of ATM response to DNA damage
    Induction: By DNA damaging agents such as UV, adriamycin, actinomycin-D and cisplatin

         Genatlas biochemistry entry for EEF1E1:
    eukaryotic translation elongation factor 1,epsilon 1

    miRNA
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    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--


    EEF1E1 for ontologies           About GeneDecksing


    Animal Models:
         5 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Eef1e1):
     cellular  hematopoietic system  immune system  mortality/aging  tumorigenesis 

    EEF1E1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for EEF1E1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1tRNA Aminoacylation
    		tRNA Aminoacylation1.00
    		Cytosolic tRNA aminoacylation0.57
    2Generic Transcription Pathway
    		Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3        Reactome Pathways for EEF1E1
        Cytosolic tRNA aminoacylation
    tRNA Aminoacylation
    Gene Expression



    EEF1E1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for EEF1E1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    5/17 Interacting proteins for EEF1E1 (O433241, 3 ENSP000003690384) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATMQ133153, ENSP000002786164I2D: score=3 STRING: ENSP00000278616
    ATRQ135353, ENSP000003437414I2D: score=3 STRING: ENSP00000343741
    ARF6P623303, ENSP000002983164I2D: score=1 STRING: ENSP00000298316
    EIF1BO607393, ENSP000002329054I2D: score=1 STRING: ENSP00000232905
    NAT9Q9BTE03I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006418tRNA aminoacylation for protein translation TAS--
    GO:0008285negative regulation of cell proliferation ISS--
    GO:0010467gene expression TAS--
    GO:0043065positive regulation of apoptotic process ISS--
    GO:0043517positive regulation of DNA damage response, signal transduction by p53 class mediator ISS--


    EEF1E1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for EEF1E1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    EEF1E1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for EEF1E1
    2 Novoseek chemical compound relationships for EEF1E1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    aminoacyl-trna 84.6 1 16169847 (1)
    trna 60.6 1 17303557 (1)

    Search CenterWatch for drugs/clinical trials and news about EEF1E1 / MCA3 

    Transcripts
    for EEF1E1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for EEF1E1 gene (2 alternative transcripts): 
    NM_001135650.1  NM_004280.4  

    Unigene Cluster for EEF1E1:

    Eukaryotic translation elongation factor 1 epsilon 1
    Hs.602353  [show with all ESTs]
    Unigene Representative Sequence: NR_037618
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000429723(uc011dic.2) ENST00000502429 ENST00000379715(uc003mxz.3)
    ENST00000507463 ENST00000515633 ENST00000488226

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    hsa-miR-204 hsa-miR-211
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    Inhib. RNA
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AB011079.1 AF054186.1 BC005291.1 BT007306.1 NR_037618.1 

    17 DOTS entries:

    DT.213502  DT.121352019  DT.100754693  DT.121352034  DT.440593  DT.92443867  DT.121351916  DT.86855247 
    DT.100025787  DT.100754695  DT.213501  DT.40232984  DT.75187873  DT.92443873  DT.95168574  DT.95168577 
    DT.95216717 

    24/1254 AceView cDNA sequences (see all 1254):

    BM754730 CA430769 AA505694 AA580400 BF173142 AI368993 AW732535 AA452349 
    BQ943586 BQ677165 BE327917 BU618789 AI694681 BG677409 AK098089 AI262639 
    CN482750 BU621817 BF173221 BQ936502 BQ953417 AA653396 BQ933447 BQ678581 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for EEF1E1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6
    SP1:                                -           -     -               
    SP2:                                -           -     -     -         
    SP3:                                -                                 
    SP4:                                                                  


    ECgene alternative splicing isoforms for EEF1E1

    Expression
    for EEF1E1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    EEF1E1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCATACAGAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See EEF1E1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for EEF1E1

    SOURCE GeneReport for Unigene cluster: Hs.602353

    UniProtKB/Swiss-Prot: MCA3_HUMAN, O43324
    Tissue specificity: Down-regulated in various cancer tissues

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    In Situ
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    Orthologs
    for EEF1E1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for EEF1E1 gene from 6/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Eef1e11 , 5 eukaryotic translation elongation factor 1 epsilon 1 less1, 5 86.59(n)1
    88.51(a)1    		   13 (18.38 cM)5
    661431  NM_025380.21  NP_079656.11 
     386456985 
    chicken
    (Gallus gallus)    		 Aves EEF1E11 eukaryotic translation elongation factor 1 epsilon 1 less 75.19(n)
    76.16(a)    		   420865  XM_418953.3  XP_418953.3 
    lizard
    (Anolis carolinensis)    		 Reptilia EEF1E16
    		 --
    		 80(a)
    		 1 → many
    		 GL343209.1(993411-1000514)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.76612 Xenopus laevis transcribed sequence with weak similarity to protein spO43324 (H.sapiens) MCA3_HUMAN Multisynthetase complex auxiliary component p18 less 75.44(n)    BJ093442.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii BI475585.12   -- 70.76(n)    BI475585.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG301856
    		 --
    		 30(a)
    		 1 → many
    		 2R(19431564-19432422)


    ENSEMBL Gene Tree for EEF1E1 (if available)
    TreeFam Gene Tree for EEF1E1 (if available) 

    Paralogs
    for EEF1E1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for EEF1E1 gene
    ENSG000002658182  
    18/93 SIMAP similar genes for EEF1E1 using alignment to 5 protein entries:     MCA3_HUMAN (see all proteins) (see all similar genes):
    FLJ00047    SUV420H1    TGM4    BIRC3    SMYD4    HINFP
    NDUFS3    NEK4    ARIH1    ARL6IP5    C12orf76    EIF3G
    TAF2    TBCB    pp12301    ACTR10    HDGFRP2    PUS1

    EEF1E1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for EEF1E1
    PGOHUM00000240865


    Genomic Variants
    for EEF1E1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/641 NCBI SNPs in EEF1E1 are shown (see all 641)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1499188131,2
    		--8073140(+) TACCTC/GAGGGA 2 -- ds5001 int10--------
    rs171433441,2
    		C,F,--8073237(+) TACATA/GTTAGG 2 -- int1 ds50014Minor allele frequency- G:0.02NA WA 260
    rs27440131,2
    		C,F,A,H,--8073368(-) CCTCAT/CCATGT 2 -- ds5001 int125Minor allele frequency- C:0.46NS EA NA WA 2760
    rs1449740081,2
    		--8073384(+) GTGCTC/TGACTC 2 -- ds5001 int10--------
    rs27440121,2
    		C,F,H,--8073385(-) GGAGTC/TGAGCA 2 -- int1 ds50019Minor allele frequency- T:0.26NS EA WA NA 778
    rs1901127461,2
    		--8073421(+) TAATGC/TTGTAA 2 -- int1 ds50010--------
    rs773184811,2
    		C,--8073589(+) TTCCAC/TAAGTT 2 -- int1 ds50010--------
    rs1499236871,2
    		C,--8073624(+) CCATG-/TAGA  
      GTAGTT    TACAG     		2 -- int1 ut310--------
    rs95053541,2
    		C,F,H,--8073658(+) GACATT/CTGTGT 2 -- int1 ut3111Minor allele frequency- C:0.09NS EA NA WA 1308
    rs1812163451,2
    		--8073680(+) TTCCTC/TGATCT 2 -- ut31 int10--------

    HapMap Linkage Disequilibrium report for EEF1E1 (8073593 - 8102828 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for EEF1E1: --

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    Disorders / Diseases
    for EEF1E1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    EEF1E1 for disorders           About GeneDecksing

    OMIM gene information: 609206    OMIM disorders: --

    8 diseases for EEF1E1:    About MalaCards
    platelet storage pool deficiency    hermansky-pudlak syndrome    norwegian scabies    cutaneous anthrax
    scabies    progeria    appendicitis    colorectal cancer

    Human Genome Epidemiology (HuGE) Navigator: EEF1E1 (2 documents)

    Export disorders for EEF1E1 gene to outside databases

    Publications
    for EEF1E1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for EEF1E1 gene, integrated from 9 sources (see all 37):
    (articles sorted by number of sources associating them with EEF1E1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full- length cDNA cloning. (PubMed id 9653160)1, 2, 3 Mao M.... Chen Z. (1998)
    2. The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR. (PubMed id 15680327)1, 2, 9 Park B.-J.... Kim S. (2005)
    3. Determination of three-dimensional structure and residues of the novel tumor suppressor AIMP3/p18 required for the interaction with ATM. (PubMed id 18343821)1, 2 Kim K.J....Kang B.S. (2008)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    6. Absence of somatic mutation of a tumor suppressor gene eukaryotic translation elongation factor 1, epsilon-1 (EEF1E1), in common human cancers. (PubMed id 19024604)1, 9 Kim M.S....Lee S.H. (2008)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    9. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
    10. AIMP3/p18 controls translational initiation by mediati ng the delivery of charged initiator tRNA to initiation complex. (PubMed id 22867704)1 Kang T....Kim S. (2012)

    External Searches for EEF1E1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    NCBI Bookshelf
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    Genome Databases showing EEF1E1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9521 HGNC: 3212 AceView: EEF1E1 Ensembl:ENSG00000124802 euGenes: HUgn9521
    ECgene: EEF1E1 H-InvDB: EEF1E1

    Other Databases showing EEF1E1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing EEF1E1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for EEF1E1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for EEF1E1 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for EEF1E1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for EEF1E1 gene:
    Search GeneIP for patents involving EEF1E1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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