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EEA1 Gene

protein-coding GIFtS: 56

GC12M091668

early endosome antigen 1
(Previous names: early endosome antigen 1, 162kD )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
MST105 ^²
MSTP105 ^²
ZFYVE2 ^¹, ², ³

Descriptions
Endosome-associated protein p162 ^³
Zinc finger FYVE domain-containing protein 2 ^³
early endosome antigen 1 ^²
early endosome antigen 1, 162kD ^¹, ²
early endosome-associated protein ^²

External Ids
HGNC: 3185¹
Entrez Gene: 8411²
UniProtKB: Q15075³
Ensembl: ENSG00000102189⁷

Search outside databases for aliases for EEA1 gene

Previous GC identifers: GC12M092561 GC12M093628 GC12M093102 GC12M091671

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: EEA1_HUMAN, Q15075

Function: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates

in endosomal trafficking

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the EEA1 gene

Entrez Gene cytogenetic band: 12q22 Ensembl cytogenetic band: 12q22 HGNC cytogenetic band: 12q22

EEA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M091668: (about GC identifiers)

Start:	91,690,416 bp from pter
End:	91,847,238 bp from pter
Size:	156,823 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000012.10 NT_019546.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: EEA1_HUMAN, Q15075 (See protein sequence)

Recommended Name: Early endosome antigen 1

Size: 1411 amino acids; 162466 Da

Subunit: Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by

GTP-binding

Subcellular location: Cytoplasm. Early endosome membrane; Peripheral membrane protein

PDB structures from and Proteopedia :

1HYI (3D)

1HYJ (3D)

1JOC (3D)

Secondary accessions: Q14221

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_003557.2

ENSEMBL proteins:

ENSP00000317955

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Sigma-Aldrich AQUA Peptides for EEA1
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (EEA1)
	Human Recombinant Proteins from Abnova (EEA1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5/8 Gene Ontology (GO) cellular component terms (links to tree view) (see all 8 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0005624	membrane fraction	TAS	7768953
GO:0005737	cytoplasm	TAS	7768953
GO:0005829	cytosol	IDA	7768953
GO:0005969	serine-pyruvate aminotransferase complex	IEA	--

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Antibodies for EEA1:

	Invitrogen Antibodies for EEA1
	Millipore Mono- and Polyclonal Antibodies for the study of EEA1
	Sigma-Aldrich Antibodies for EEA1
	Browse R&D Systems for Antibodies
	Cell Signaling Technology (CST) Antibodies for EEA1
	Antibodies from Abcam (EEA1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (EEA1)
	Novus Biologicals Antibodies for EEA1

Assays for EEA1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q15075

ProtoNet protein and cluster: Q15075

1 Blocks protein family: IPB000306 Zn-finger

UniProtKB/Swiss-Prot: EEA1_HUMAN, Q15075

Domain: The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol

3-phosphate

Similarity: Contains 1 C2H2-type zinc finger

Similarity: Contains 1 FYVE-type zinc finger

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EEA1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (EEA1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003566

Applied Biosystems Silencer® siRNAs for EEA1

Sigma-Aldrich siRNA for EEA1

Sigma-Aldrich shRNA for EEA1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_003566
Myc/DDK tagged cDNA clone in CMV expression vector: NM_003566
untagged cDNA clone in CMV expression vector: NM_003566

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_003566

UniProtKB/Swiss-Prot: EEA1_HUMAN, Q15075

Function: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates

in endosomal trafficking

5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005516	calmodulin binding	NAS	11741531
GO:0005545	phosphatidylinositol binding	IDA	11256955
GO:0008270	zinc ion binding	TAS	11741531
GO:0030742	GTP-dependent protein binding	IDA	10491193
GO:0042803	protein homodimerization activity	IDA	11741531

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for EEA1

5/41 Interacting proteins for EEA1 (Q15075^{1, 2} ENSP00000317955³) via UniProtKB, MINT, and/or STRING (see all 41 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RAB5B	P61020¹, ENSP00000353444³	EBI-298113, EBI-399401 STRING (score=.994)
RAB22A	Q9UL26¹, ENSP00000244040³	EBI-298113, EBI-399456 STRING (score=.827)
ZFYVE16	Q7Z3T8¹, ENSP00000337159³	EBI-298113, EBI-298055 STRING (score=.749)
RAB5A	P20339¹^,², ENSP00000273047³	EBI-298113, EBI-399437 MINT-2883035 EBI-298113, EBI-399437 MINT-2883035 STRING (score=.999)
TOM1	O60784¹	EBI-298113, EBI-74634

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006906	vesicle fusion	IMP	9697774
GO:0016189	synaptic vesicle to endosome fusion	TAS	11741531
GO:0045022	early endosome to late endosome transport	NAS	7768953

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for EEA1
10 Novoseek chemical compound relationships for EEA1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
phosphatidylinositol 3-phosphate	92.12	34	11602609 (5), 12857876 (4), 11329382 (2), 16522686 (1) (see all 13)
ptdins(3)p	84.08	21	11564757 (3), 11329382 (3), 16141328 (2), 10652369 (2) (see all 9)
wortmannin	63.74	2	14521088 (1), 10332740 (1)
phosphatidylinositol	58.11	10	16522686 (1), 12911814 (1), 17651088 (1), 10332740 (1) (see all 7)
phosphoinositide	51.59	1	16141328 (1)
mannose 6-phosphate	34.83	2	11404461 (1)
cholesterol	12.74	2	12584196 (2)
lipid	12.67	1	14578346 (1)
tyrosine	11.46	2	11370743 (1), 11918675 (1)
zinc	0.00	4	14597214 (1), 17890395 (1), 10458612 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EEA1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (EEA1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003566

Sigma-Aldrich siRNA for EEA1

Sigma-Aldrich shRNA for EEA1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_003566

REFSEQ mRNAs for EEA1 gene:

NM_003566.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_003566

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_003566
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_003566
                                 untagged cDNA clone in CMV expression vector: NM_003566

Additional cDNA sequence:

AF173389.1 AK292008.1 AK307918.1 BC017837.1 BC041930.1 BX648463.1 L40157.1 X78998.1

5 DOTS entries:

DT.312811 DT.100790733 DT.121114015 DT.86841244 DT.91938349

24/163 AceView cDNA sequences (see all 163 ):

BF515615 BU160820 R58333 BX495378 AW954338 BU161988 BG493301 BI092315

H38659 BE218993 CA313002 CA435240 BF512066 AI918294 BC017837 X78998

BQ954298 AI815086 BU620283 AU139787 BE018194 AA278514 AA130246 CB157397

highest scoring ESTs for EEA1:

L40157 AU139787 BC017837 BF574207 H99557 X78998 AA012970 AA039504 AA133971 AA258032

Unigene Cluster for EEA1:

Early endosome antigen 1

Hs.567367 [show with all ESTs]

Unigene Representative Sequence: NM_003566

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000322349

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

EEA1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for EEA1

¹ / ² / ³

8 probe-sets matching EEA1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
50373_at²^{, 3}	U95-B	1	1.00	1.00	1.00	1.00	AI336848	0.60	1.00	0.82	1
39627_at²^{, 3}	U95-A	1	0.75	1.00	0.56	0.38	L40157	1.00	1.00	1.00	1
225885_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AI336848	0.60	1.00	0.82	1
204841_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_003566	0.60	1.00	0.82	1
204840_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI916242	0.60	1.00	0.82	1
225885_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
204841_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
204840_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks EEA1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TAGTTGTGCC

SOURCE GeneReport for Unigene cluster: Hs.567367
Expression variation in blood from EXPOLDB for EEA1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for EEA1 gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	EEA1¹	--	early endosome antigen 1	91.49(n) 91.47(a)	475424 XM_532649.2 XP_532649.2
chimpanzee (Pan troglodytes)	EEA1¹	--	early endosome antigen 1	99.74(n) 99.65(a)	467212 XM_522610.2 XP_522610.2
cow (Bos taurus)	EEA1¹	--	early endosome antigen 1	89.12(n) 88.55(a)	516259 XM_594411.3 XP_594411.3
rat (Rattus norvegicus)	Eea1¹	--	early endosome antigen 1	84.91(n) 85.53(a)	314764 XM_235064.4 XP_235064.4
mouse (Mus musculus)	Eea1^{1, 5}	10⁵	early endosome antigen 1^{1, 5}	84.53(n)¹ 85.97(a)¹	216238¹ NM_001001932.3¹ NP_001001932.1¹ AI155285⁵ AK020788⁵ (see all 16)

About this table Species with no ortholog for EEA1

ENSEMBL Gene Tree for EEA1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for EEA1 gene

PCNT² TPR² AKAP9²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/729 NCBI SNPs in EEA1 are shown (see all 729 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 159)

AB	SNP ID	Valid	Chr 12 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
--	rs3203635^1,2	A,C,F,H	91693255(-)	`AAAAAT/CCTCTG`	1	--	ut3¹		5	MN EU EA WA	598
	rs10745623^1,2	A,C,F,H	91720553(+)	`GATTTG/TTTTTT`	1	Q/K	mis¹ trp³		8	EU EA WA	834
	rs10735304^1,2	A,C,F,H	91690669(+)	`CCCAAG/AAACTA`	1	--	ut3¹		7	NA EU EA WA	560
	rs12304974^1,2	A,F,H	91691850(+)	`TGTGAG/ATATTT`	1	--	ut3¹		4	EU EA WA	416
	rs4600254^1,2	C,F,H	91847807(+)	`TTCAGC/TCAAAG`	1	--	ng3¹		4	EU EA WA	418
	rs10777451^1,2	C,F,H	91691990(+)	`GTGAAC/TATCTG`	1	--	ut3¹		4	EU EA WA	410
	rs17194416^1,2	C,F,H	91691566(+)	`TAACTG/CACTGA`	1	--	ut3¹		11	NA EU EA WA	980
	rs17020718^1,2	F,H	91690524(+)	`GTCACG/ATACTT`	1	--	ut3¹		7	NA EU EA WA	562
	rs17020720^1,2	F,H	91690943(+)	`TGGCAC/TGTTAT`	1	--	ut3¹		7	NA EU EA WA	562
	rs11106698^1,2	H	91692960(+)	`CAGATC/ATATGT`	1	--	ut3¹		4	EU EA WA	412

About this table

HapMap Linkage Disequilibrium images for EEA1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 605070

UniProtKB/Swiss-Prot: EEA1_HUMAN, Q15075

Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus

erythematosus and other autoimmune diseases

3 Novoseek disease relationships for EEA1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
neurological disorders	32.01	6	17113235 (1), 11122260 (1), 14962794 (1), 14728723 (1)
wegeners granulomatosis	23.37	1	11122260 (1)
tuberculosis	0.00	1	11581282 (1)

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(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/121 PubMed articles for EEA1 gene (see all 121 ):

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion. (PubMed id 9697774)^{1, 2, 3, 4} Simonsen A....Stenmark H. (1998)
EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine 'fingers' and contains a calmodulin-binding IQ motif. (PubMed id 7768953)^{2, 3, 4} Mu F.-T....Toh B.-H. (1995)
The Rab5 effector EEA1 interacts directly with syntaxin-6. (PubMed id 10506127)^{1, 3, 4} Simonsen A.... Stenmark H. (1999)
Direct interaction of EEA1 with Rab5b. (PubMed id 10491193)^{1, 3, 4} Callaghan J.M.... Stenmark H. (1999)
Structural mechanism of endosome docking by the FYVE domain. (PubMed id 11230696)^{1, 3, 4} Kutateladze T.G. and Overduin M. (2001)
Determinants of Rab5 interaction with the N-terminus of early endosome antigen 1. (PubMed id 12493736)^{3, 4} Merithew E.... Lambright D.G. (2003)
The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking. (PubMed id 11870209)^{3, 4} Kauppi M.... Olkkonen V.M. (2002)
Multivalent endosome targeting by homodimeric EEA1. (PubMed id 11741531)^{3, 4} Dumas J.J.... Lambright D.G. (2001)
Interaction of the EEA1 FYVE finger with phosphatidylinositol 3- phosphate and early endosomes. Role of conserved residues. (PubMed id 10807926)^{3, 4} Gaullier J.-M.... Stenmark H. (2000)
Phosphatidylinositol 3-phosphate recognition by the FYVE domain. (PubMed id 10394369)^{3, 4} Kutateladze T.G.... Overduin M. (1999)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 8411	HGNC: 3185	AceView: EEA1	Ensembl:ENSG00000102189	euGenes: HUgn8411
ECgene: EEA1	H-InvDB: EEA1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for EEA1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for EEA1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for EEA1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for EEA1		Antibodies for EEA1
	Explore super-pooled esiRNAs		Proteins for EEA1
	Lentivirus-delivered shRNAs for EEA1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (EEA1)
	Antibodies (EEA1)
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	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for EEA1

	Recombinant Proteins (EEA1)
	Antibodies (EEA1)

Search OriGene for EEA1

Search Tocris compounds for EEA1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for EEA1

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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EEA1 Gene

protein-coding GIFtS: 56

Aliases &
Descriptions
for EEA1

Summaries
for EEA1

Genomic Location
for EEA1

Proteins
for EEA1

Protein Domains/
Families
for EEA1

Gene Function
for EEA1

Pathways & Interactions
for EEA1

Drugs & Compounds
for EEA1

Transcripts
for EEA1

Expression
for EEA1

Orthologs
for EEA1

Paralogs
for EEA1

SNPs/Variants
for EEA1

Disorders & Mutations
for EEA1

Medical News
for EEA1

Publications
for EEA1

Search for EEA1

Genome Databases showing EEA1

Other Databases showing EEA1

Specialized Databases showing EEA1

Licensable Technologies
for EEA1

Services
for EEA1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

EEA1 Gene

protein-coding GIFtS: 56

Aliases & Descriptionsfor EEA1

Summariesfor EEA1

Genomic Locationfor EEA1

Proteinsfor EEA1

Protein Domains/Familiesfor EEA1

Gene Functionfor EEA1

Pathways & Interactionsfor EEA1

Drugs & Compoundsfor EEA1

Transcriptsfor EEA1

Expression for EEA1

Orthologsfor EEA1

Paralogsfor EEA1

SNPs/Variantsfor EEA1

Disorders & Mutationsfor EEA1

Medical Newsfor EEA1

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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