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S1PR4 Gene

protein-coding GIFtS: 53

GC19P003130

sphingosine-1-phosphate receptor 4
(Previous names: endothelial differentiation, G-protein-coupled receptor 6, endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: EDG6)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EDG6 ^², ³, ⁵
LPC1 ^²
S1P4 ^², ³, ⁵
SLP4 ^²

Descriptions
Endothelial differentiation G-protein coupled receptor 6 ^³
S1P receptor 4 ^³
S1P receptor Edg-6 ^³
Sphingosine 1-phosphate receptor 4 ^²
Sphingosine 1-phosphate receptor Edg-6 ^², ³
endothelial differentiation, G protein coupled receptor 6 ^²
endothelial differentiation, G-protein-coupled receptor 6 ^¹, ²
endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6 ^¹, ²
sphingosine-1-phosphate receptor 4 ^²

External Ids
HGNC: 3170¹
Entrez Gene: 8698²
UniProtKB: O95977³
Ensembl: ENSG00000125910⁷

Search outside databases for aliases for S1PR4 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for S1PR4:

This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene

family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in

cell signalling in many different cell types. This EDG receptor gene is intronless and is

specifically expressed in the lymphoid tissue. [provided by RefSeq]

UniProtKB/Swiss-Prot: S1PR4_HUMAN, O95977

Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive

lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May

be involved in cell migration processes that are specific for lymphocytes

Gene Wiki entry for S1PR4 (EDG6)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3

S1PR4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P003130: (about GC identifiers)

Start:	3,129,766 bp from pter
End:	3,131,330 bp from pter
Size:	1,565 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000019.8 NT_011255.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: S1PR4_HUMAN, O95977 (See protein sequence)

Recommended Name: Sphingosine 1-phosphate receptor 4

Size: 384 amino acids; 41623 Da

Subcellular location: Cell membrane; Multi-pass membrane protein

PDB structures from and Proteopedia :

2DCO (3D)

REFSEQ proteins: NP_003766.1

ENSEMBL proteins:

ENSP00000246115

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Millipore Purified and/or Recombinant S1PR4 Protein
	Sigma-Aldrich Proteins for S1PR4
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (EDG6)
	Human Recombinant Proteins from Abnova (S1PR4)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0005887	integral to plasma membrane	TAS	9790765

About this table

Antibodies for S1PR4:

	Invitrogen Antibodies for S1PR4
	Millipore Mono- and Polyclonal Antibodies for the study of S1PR4
	Sigma-Aldrich Antibodies for S1PR4
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (EDG6), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (S1PR4)
	Novus Biologicals Antibody for S1PR4

Assays for S1PR4:

	Invitrogen Assays for S1PR4
	Millipore Kits and Assays for the Analysis of S1PR4
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry O95977

ProtoNet protein and cluster: O95977

2 Blocks protein families:

IPB004061 Sphingosine 1-phosphate receptor family signature

IPB004064 EDG-6 sphingosine 1-phosphate receptor signature

UniProtKB/Swiss-Prot: S1PR4_HUMAN, O95977

Similarity: Belongs to the G-protein coupled receptor 1 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (S1PR4)
		Millipore RNAi Products for the Analysis of S1PR4 Gene knock-down
		Abnova Chimera RNAi Products for Gene knock-down (S1PR4)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003775

Applied Biosystems Silencer® siRNAs for S1PR4

Sigma-Aldrich siRNA and siRNA Panels for S1PR4

Sigma-Aldrich shRNA Panels and shRNA for S1PR4

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for S1PR4
		Millipore Clones for the Expression of S1PR4

OriGene GFP tagged cDNA clone in CMV expression vector: NM_003775
Myc/DDK tagged cDNA clone in CMV expression vector: NM_003775
untagged cDNA clones in CMV expression vector (see all 2): NM_003775

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_003775

UniProtKB/Swiss-Prot: S1PR4_HUMAN, O95977

Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive

lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May

be involved in cell migration processes that are specific for lymphocytes

2 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for S1pr4):

lethality-prenatal/perinatal

nervous system

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001619	lysosphingolipid and lysophosphatidic acid receptor activity	IEA	--
GO:0004872	receptor activity	IEA	--
GO:0004930	G-protein coupled receptor activity	TAS	10679247
GO:0008289	lipid binding	TAS	10679247

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for S1PR4 (Your Favorite Gene powered by Ingenuity)

Ceramide Signaling
Human Embryonic Stem Cell Pluripotency

GeneDecks S1PR4 for the pathways selected above

About GeneDecksing

5/21 Interacting proteins for S1PR4 (ENSP00000246115³) via UniProtKB, MINT, and/or STRING (see all 21 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GNA12	ENSP00000275364³	STRING (score=.96)
GNA13	ENSP00000239138³	STRING (score=.96)
CDC42P2	ENSP00000314458³	STRING (score=.933)
MBTPS1	ENSP00000344223³	STRING (score=.915)
GNAI2	ENSP00000312999³	STRING (score=.904)

About this table

5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006955	immune response	TAS	9790765
GO:0007165	signal transduction	IEA	--
GO:0007186	G-protein coupled receptor protein signaling pathway	TAS	9790765
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway	IEA	--
GO:0007202	activation of phospholipase C activity	TAS	10679247

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Sigma-Aldrich Small Molecules for S1PR4:

Mixed Agonist/Antagonist Antagonist

Compounds for S1PR4 available from Tocris Bioscience

Compound	Action	CAS number
Sphingosine-1-phosphate	Endogenous agonist at S1P1-5	[26993-30-6]

About this table

1 Novoseek chemical compound relationship for S1PR4 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
lysophospholipid	85.59	1	10753843 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (S1PR4)
		Millipore RNAi Products for the Analysis of S1PR4 Gene knock-down
		Abnova Chimera RNAi Products for Gene knock-down (S1PR4)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003775

Sigma-Aldrich siRNA and siRNA Panels for S1PR4

Sigma-Aldrich shRNA Panels and shRNA for S1PR4

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_003775

REFSEQ mRNAs for S1PR4 gene:

NM_003775.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_003775

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_003775
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_003775
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_003775

Additional cDNA sequence:

AJ000479.1 BC014970.1 CR590635.1 CR608611.1 CR610253.1

1 DOTS entry:

DT.75163397

24/49 AceView cDNA sequences (see all 49 ):

BC014970 CR590635 BI906435 AL560216 CA314158 BG744043 BI908610 CR610253

CR608611 AW451146 BI907726 AA353166 BG685195 NM_003775 CD370174 AJ000479

BI762628 BG397972 CB529025 BQ053747 BX119598 BI909157 AL560608 BI910894

Unigene Cluster for S1PR4:

Sphingosine-1-phosphate receptor 4

Hs.662006 [show with all ESTs]

Unigene Representative Sequence: NM_003775

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000246115

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

S1PR4 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for S1PR4

¹ / ²

3 probe-sets matching S1PR4 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
33602_at²	U95-A	1	1.00	1.00	1.00	1.00	--	--	--	--	--
206437_at²	U133-A	1	1.00	1.00	--	--	--	--	--	--	--
206437_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks S1PR4 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CCCTGGCAAC

SOURCE GeneReport for Unigene cluster: Hs.662006
UniProtKB/Swiss-Prot: S1PR4_HUMAN, O95977
Tissue specificity: Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as
well as in lung. Considerable level of expression in adult and fetal spleen as well as adult
peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and
appendix as well as in fetal liver, thymus, and lung

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for S1PR4 gene from 5/7 species (see all 7 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	S1PR4¹	--	sphingosine-1-phosphate receptor 4	87.43(n) 86.39(a)	612082 XM_849809.1 XP_854902.1
chimpanzee (Pan troglodytes)	S1PR4¹	--	sphingosine-1-phosphate receptor 4	99.65(n) 100(a)	455581 XM_512266.2 XP_512266.2
cow (Bos taurus)	S1PR4¹	--	sphingosine-1-phosphate receptor 4	85.5(n) 85.94(a)	539534 XM_587940.3 XP_587940.1
rat (Rattus norvegicus)	S1pr4¹	--	sphingosine-1-phosphate receptor 4	80.37(n) 83.55(a)	314649 XM_234930.3 XP_234930.1
mouse (Mus musculus)	S1pr4^{1, 5}	10⁵	sphingosine-1-phosphate receptor 4^{1, 5}	81.17(n)¹ 83.29(a)¹	13611¹ NM_010102.1¹ NP_034232.1¹ AA254425⁵ AJ006074⁵ (see all 10)

About this table Species with no ortholog for S1PR4

ENSEMBL Gene Tree for S1PR4

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for S1PR4 gene

LPAR2² LPAR1² LPAR3²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/77 NCBI SNPs in S1PR4 are shown (see all 77 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 36)

AB	SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs311629^1,2	A,C,F,H	3131803(+)	`CTGACG/AACTGC`	1	--	ng3¹		5		MN EU EA	1960
	rs311630^1,2	A,C,F,H	3131770(+)	`TTGATT/GGTACA`	1	--	ng3¹		13		EU EA WA	2760
	rs3786944^1,2	C,F,H	3129372(-)	`GCGCTC/TAGCAC`	1	--	ng5¹		8		EU EA WA	840
	rs3746071^1,2	C,F,H	3131827(-)	`CTCCAC/GTGGAG`	1	--	ng3¹		5		EA EU WA	1892
--	rs567806^1,2	A,C	3128279(-)	`CTGGCA/GTCTGA`	1	--	ng5¹		0	--	--	--	--
--	rs311631^1,2	A,C	3131471(+)	`TGGAGA/TGTGTG`	1	--	ng3¹		0	--	--	--	--
	rs311632^1,2	A,C	3131369(+)	`GCATGC/TGTGGG`	1	--	ng3¹		0	--	--	--	--
--	rs7250717^1,2	A,C	3128815(+)	`AACGCA/CTCGGG`	1	--	ng5¹		0	--	--	--	--
--	rs3746072^1,2	F,H	3130884(-)	`GCGAGC/AGGGAG`	1	L/R	mis¹ ese³		5		EA EU WA	1890
--	rs10404604^1,2	A	3127952(+)	`GCCTCA/GCCTCC`	1	--	ng5¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for S1PR4 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 603751

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/23 PubMed articles for S1PR4 gene (see all 23 ):

EDG6, a novel G protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue. (PubMed id 9790765)^{2, 3, 4} Graeler M.H.... Lipp M. (1998)
Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6. (PubMed id 10753843)^{1, 3, 4} Van Brocklyn J.R....Spiegel S. (2000)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway. (PubMed id 10679247)^{3, 4} Yamazaki Y.... Ohta H. (2000)
A single amino acid determines preference between phospholipids and reveals length restriction for activation of the S1P4 receptor. (PubMed id 15298705)^{1, 3} Holdsworth G....Parrill A.L. (2004)
Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses. (PubMed id 11919175)^{1, 3} Idzko M....Norgauer J. (2002)
FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase. (PubMed id 18713968)³ Fabre S....Bismuth G. (2008)
Peptide design and structural characterization of a GPCR loop mimetic. (PubMed id 17443712)⁴ Pham T.C....Parrill A.L. (2007)
Sphingosine-1-phosphate and its potentially paradoxical effects on critical parameters of cutaneous wound healing. (PubMed id 12648236)³ Vogler R....Kleuser B. (2003)
The sphingosine 1-phosphate receptor S1P4 regulates cell shape and motility via coupling to Gi and G12/13. (PubMed id 12761884)³ Graler M.H....Lipp M. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 8698	HGNC: 3170	AceView: EDG6	Ensembl:ENSG00000125910	euGenes: HUgn8698
ECgene: S1PR4	H-InvDB: S1PR4

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for S1PR4
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for S1PR4:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for S1PR4-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for S1PR4		Antibodies for S1PR4
	Explore super-pooled esiRNAs		Proteins for S1PR4
	Lentivirus-delivered shRNAs for S1PR4		Small molecules for S1PR4
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (S1PR4)
	Antibodies (S1PR4)
	Chimera RNAi (S1PR4)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (EDG6)
	Antibodies (EDG6)

Search OriGene for S1PR4

Tocris compounds for S1PR4

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for S1PR4

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S1PR4 Gene at Home site.
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S1PR4 Gene

protein-coding GIFtS: 53

Aliases &
Descriptions
for S1PR4

Summaries
for S1PR4

Genomic Location
for S1PR4

Proteins
for S1PR4

Protein Domains/
Families
for S1PR4

Gene Function
for S1PR4

Pathways & Interactions
for S1PR4

Drugs & Compounds
for S1PR4

Transcripts
for S1PR4

Expression
for S1PR4

Orthologs
for S1PR4

Paralogs
for S1PR4

SNPs/Variants
for S1PR4

Disorders & Mutations
for S1PR4

Medical News
for S1PR4

Publications
for S1PR4

Search for S1PR4

Genome Databases showing S1PR4

Other Databases showing S1PR4

Specialized Databases showing S1PR4

Licensable Technologies
for S1PR4

Services
for S1PR4

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

S1PR4 Gene

protein-coding GIFtS: 53

Aliases & Descriptionsfor S1PR4

Summariesfor S1PR4

Genomic Locationfor S1PR4

Proteinsfor S1PR4

Protein Domains/Familiesfor S1PR4

Gene Functionfor S1PR4

Pathways & Interactionsfor S1PR4

Drugs & Compoundsfor S1PR4

Transcriptsfor S1PR4

Expression for S1PR4

Orthologsfor S1PR4

Paralogsfor S1PR4

SNPs/Variantsfor S1PR4

Disorders & Mutationsfor S1PR4

Medical Newsfor S1PR4

Publicationsfor S1PR4

Search for S1PR4

Genome Databases showing S1PR4

Other Databases showing S1PR4

Specialized Databases showing S1PR4

Licensable Technologiesfor S1PR4

Servicesfor S1PR4

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for S1PR4

Summaries
for S1PR4

Genomic Location
for S1PR4

Proteins
for S1PR4

Protein Domains/
Families
for S1PR4

Gene Function
for S1PR4

Pathways & Interactions
for S1PR4

Drugs & Compounds
for S1PR4

Transcripts
for S1PR4

Expression
for S1PR4

Orthologs
for S1PR4

Paralogs
for S1PR4

SNPs/Variants
for S1PR4

Disorders & Mutations
for S1PR4

Medical News
for S1PR4

Publications
for S1PR4

Licensable Technologies
for S1PR4

Services
for S1PR4