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S1PR2 Gene

protein-coding GIFtS: 51

GC19M010193

sphingosine-1-phosphate receptor 2
(Previous names: endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: EDG5)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
AGR16 ^¹, ²
EDG-5 ^²
EDG5 ^², ³, ⁵
Gpcr13 ^¹, ²
H218 ^¹, ²
LPB2 ^²
S1P2 ^², ³

Descriptions
Endothelial differentiation G-protein coupled receptor 5 ^³
S1P receptor 2 ^³
S1P receptor EDG5 ^²
S1P receptor Edg-5 ^³
Sphingosine 1-phosphate receptor Edg-5 ^³
endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 ^¹, ²
sphingosine 1-phosphate receptor 2 ^²
sphingosine-1-phosphate receptor 2 ^²

External Ids
HGNC: 3169¹
Entrez Gene: 9294²
UniProtKB: O95136³
Ensembl: ENSG00000175898⁷

Search outside databases for aliases for S1PR2 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for S1PR2:

This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of

proteins. This protein participates in sphingosine 1-phosphate-induced cell proliferation,

survival, and transcriptional activation [provided by RefSeq]

UniProtKB/Swiss-Prot: S1PR2_HUMAN, O95136

Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive

lysophospholipid that elicits diverse physiological effect on most types of cells and tissues.

When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation

and suppression of apoptosis

Gene Wiki entry for S1PR2 (EDG5)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2 Ensembl cytogenetic band: 19p13.2 HGNC cytogenetic band: 19q13

S1PR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19M010193: (about GC identifiers)

Start:	10,193,109 bp from pter
End:	10,202,948 bp from pter
Size:	9,840 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000019.8 NT_011295.10

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: S1PR2_HUMAN, O95136 (See protein sequence)

Recommended Name: Sphingosine 1-phosphate receptor 2

Size: 353 amino acids; 38867 Da

Subcellular location: Cell membrane; Multi-pass membrane protein

PDB structures from and Proteopedia :

1ZTI (3D)

Secondary accessions: Q86UN8

REFSEQ proteins: NP_004221.3

ENSEMBL proteins:

ENSP00000322049

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Millipore Purified and/or Recombinant S1PR2 Protein
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (EDG5)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

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Antibodies for S1PR2:

	Invitrogen Antibodies for S1PR2
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for S1PR2
	R&D Systems Antibodies for S1PR2 (EDG-5)
	Antibodies from Abcam (EDG5), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for S1PR2

Assays for S1PR2:

	Browse Invitrogen for biochemical assays
	Millipore Kits and Assays for the Analysis of S1PR2
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry O95136

ProtoNet protein and cluster: O95136

2 Blocks protein families:

IPB004061 Sphingosine 1-phosphate receptor family signature

IPB004063 EDG-5 sphingosine 1-phosphate receptor signature

UniProtKB/Swiss-Prot: S1PR2_HUMAN, O95136

Similarity: Belongs to the G-protein coupled receptor 1 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (S1PR2)
		Millipore RNAi Products for the Analysis of S1PR2 Gene knock-down
		Abnova Chimera RNAi Products for Gene knock-down (EDG5)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004230

Applied Biosystems Silencer® siRNAs for S1PR2

Sigma-Aldrich siRNA and siRNA Panels for S1PR2

Sigma-Aldrich shRNA Panels and shRNA for S1PR2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Millipore Clones for the Expression of S1PR2

OriGene GFP tagged cDNA clone in CMV expression vector: NM_004230
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004230
untagged cDNA clone in CMV expression vector: NM_004230

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004230

UniProtKB/Swiss-Prot: S1PR2_HUMAN, O95136

Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive

lysophospholipid that elicits diverse physiological effect on most types of cells and tissues.

When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation

and suppression of apoptosis

10 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for S1pr2):

	behavior/neurological	hearing/vestibular/ear	homeostasis/metabolism	lethality-prenatal/perinatal
life span-post-weaning/aging	nervous system	pigmentation	reproductive system	skin/coat/nails

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001619	lysosphingolipid and lysophosphatidic acid receptor activity	IEA	--
GO:0004872	receptor activity	IEA	--
GO:0004930	G-protein coupled receptor activity	TAS	8087418
GO:0008289	lipid binding	TAS	10617617

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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3 Sigma-Aldrich "Your Favorite Gene" Pathways for S1PR2 (Your Favorite Gene powered by Ingenuity)

G-Protein Coupled Receptor Signaling
Ceramide Signaling
Human Embryonic Stem Cell Pluripotency

GeneDecks S1PR2 for the pathways selected above

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5/27 Interacting proteins for S1PR2 (ENSP00000322049³) via UniProtKB, MINT, and/or STRING (see all 27 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GNAQ	ENSP00000286548³	STRING (score=.976)
GNA13	ENSP00000239138³	STRING (score=.96)
MBTPS1	ENSP00000344223³	STRING (score=.959)
MAPK1	ENSP00000215832³	STRING (score=.943)
MAPK3	ENSP00000263025³	STRING (score=.94)

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5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000187	activation of MAPK activity	TAS	10617617
GO:0007165	signal transduction	IEA	--
GO:0007186	G-protein coupled receptor protein signaling pathway	TAS	10617617
GO:0007610	behavior	IEA	--
GO:0008284	positive regulation of cell proliferation	TAS	10617617

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
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Browse drugs & compounds from Enzo Life Sciences

Sigma-Aldrich Small Molecules for S1PR2:

Mixed Agonist/Antagonist Antagonist

Compounds for S1PR2 available from Tocris Bioscience

Compound	Action	CAS number
Sphingosine-1-phosphate	Endogenous agonist at S1P1-5	[26993-30-6]
JTE 013	S1P2 receptor antagonist	[547756-93-4]

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5 Novoseek chemical compound relationships for S1PR2 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
dhs-1-p	91.64	1	10626811 (1)
sphingosylphosphorylcholine	86.63	5	9854026 (2), 9409733 (1), 10381367 (1)
sphingosine	85.78	2	10617617 (1), 12445827 (1)
lysophospholipid	82.15	1	10753843 (1)
calcium	16.71	14	10220556 (6), 9854026 (3), 10383399 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (S1PR2)
		Millipore RNAi Products for the Analysis of S1PR2 Gene knock-down
		Abnova Chimera RNAi Products for Gene knock-down (EDG5)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004230

Sigma-Aldrich siRNA and siRNA Panels for S1PR2

Sigma-Aldrich shRNA Panels and shRNA for S1PR2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004230

REFSEQ mRNAs for S1PR2 gene:

NM_004230.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_004230

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004230
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_004230
                                 untagged cDNA clone in CMV expression vector: NM_004230

Additional cDNA sequence:

AF034780.1 BC069598.1

2 DOTS entries:

DT.213753 DT.436424

24/307 AceView cDNA sequences (see all 307 ):

CA487223 X63692 CD674539 BX643600 AA323060 BG250085 BU616665 CB216709

BU430482 AU124455 AU130313 AU130388 BC069598 BF981884 AU131749 BU689493

BE694052 CF137722 AI422863 AW503302 BQ012349 CR607451 BF037423 CF138296

Unigene Cluster for S1PR2:

Sphingosine-1-phosphate receptor 2

Hs.655405 [show with all ESTs]

Unigene Representative Sequence: NM_004230

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000317726

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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S1PR2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for S1PR2

¹ / ²

7 probe-sets matching S1PR2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34086_at²	U95-A	1	1.00	1.00	0.77	0.64	--	--	--	--	--
47156_at²	U95-B	1	1.00	1.00	0.79	0.73	--	--	--	--	--
63906_f_at²	U95-C	3341	0.75	0.00	0.60	1.64	--	--	--	--	--
227684_at²	U133-B	1	1.00	1.00	--	--	--	--	--	--	--
208537_at²	U133-A	1	1.00	1.00	--	--	--	--	--	--	--
227684_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
208537_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks S1PR2 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.655405

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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Orthologs for S1PR2 gene from 5 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	S1PR2¹	--	sphingosine-1-phosphate receptor 2	86.17(n) 89.77(a)	484959 XM_542076.2 XP_542076.1
cow (Bos taurus)	S1PR2¹	--	sphingosine-1-phosphate receptor 2	87.41(n) 88.64(a)	540305 XM_593074.3 XP_593074.1
rat (Rattus norvegicus)	S1pr2¹	--	sphingosine-1-phosphate receptor 2	82.48(n) 90.34(a)	29415 NM_017192.1 NP_058888.1
mouse (Mus musculus)	S1pr2^{1, 5}	9 (6.00 cM)⁵	sphingosine-1-phosphate receptor 2^{1, 5}	83.33(n)¹ 90.91(a)¹	14739¹ NM_010333.3¹ NP_034463.2¹ AF108020⁵ AK003144⁵ (see all 17)
zebrafish (Danio rerio)	edg5²	--	endothelial differentiation, sphingolipid G-protein-coupled more	74.65(n)	170457 AF260256.1

About this table Species with no ortholog for S1PR2

ENSEMBL Gene Tree for S1PR2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for S1PR2 gene

S1PR3² S1PR1² S1PR5²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/74 NCBI SNPs in S1PR2 are shown (see all 74 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 27)

AB	SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs968229^1,2	A,C,F,H	10204032(-)	`acacaT/CaTCAT`	1	--	ng3¹		7		EU EA WA NA	552
	rs3745268^1,2	C,F,H	10196403(-)	`GGCCCG/AAAACA`	1	Q/R	mis¹ ese³		9		EA EU WA	2336
	rs10409243^1,2	C,F,H	10193988(+)	`AGACAC/TAGCGG`	1	--	ut3¹		8		EU EA WA	840
	rs2116941^1,2	C,F,H	10195443(+)	`CCCCAC/AGTCTC`	1	--	ut3¹		4		EU EA WA	420
--	rs11672059^1,2	C	10194811(+)	`gcactC/Ttccag`	1	--	ut3¹		0	--	--	--	--
	rs10415075^1,2	H	10194288(+)	`TGGACC/TTCAGC`	1	--	ut3¹		4		EU EA WA	416
--	rs11880277^1,2	A	10194774(+)	`ggaggC/Tggagg`	1	--	ut3¹		0	--	--	--	--
	rs2116942^1,2	A,C	10195663(+)	`CGGCCG/TCCAGC`	1	R/R	syn¹		0	--	--	--	--
	rs7250265^1,2	A,C,F,H	10200818(+)	`AGTAGC/GATGGC`	1	--	int¹		4		EU EA WA	412
	rs2288937^1,2	C,F,H	10201912(+)	`TATCCA/GCGCTC`	1	--	int¹		9		EA EU WA	2320

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HapMap Linkage Disequilibrium images for S1PR2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 605111

3 Novoseek disease relationships for S1PR2 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
glioblastoma	47.54	1	15867375 (1)
glioma	35.35	3	11146117 (3)
breast cancer	0.00	1	10493533 (1)

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(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/71 PubMed articles for S1PR2 gene (see all 71 ):

Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5. (PubMed id 10617617)^{1, 3, 4} An S.... Bleu T. (2000)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9. (PubMed id 8878560)^{2, 3} Yamaguchi F....Brenner S. (1996)
Cloning and characterization of a putative G-protein coupled receptor potentially involved in development. (PubMed id 8087418)^{2, 3} MacLennan A.J....Shaw G. (1994)
Induction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2. (PubMed id 18922980)^{1, 3} Li M.H....Ferrer F. (2008)
Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218. (PubMed id 9988698)^{1, 3} Van Brocklyn J.R....Spiegel S. (1999)
Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5. (PubMed id 10383399)^{1, 3} Ancellin N. and Hla T. (1999)
Cell type-specific localization of human cardiac S1P receptors. (PubMed id 11967277)^{1, 3} Mazurais D....Calmels T. (2002)
Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist. (PubMed id 12445827)^{1, 3} Osada M....Ozaki Y. (2002)
Specific and overlapping sphingosine-1-phosphate receptor functions in human synoviocytes: impact of TNF-alpha. (PubMed id 18658144)^{1, 3} Zhao C....Bourgoin S.G. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 9294	HGNC: 3169	AceView: EDG5	Ensembl:ENSG00000175898	euGenes: HUgn9294
ECgene: S1PR2	H-InvDB: S1PR2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for S1PR2
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for S1PR2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for S1PR2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for S1PR2		Antibodies for S1PR2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for S1PR2		Small molecules for S1PR2
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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	Custom Service for Rabbit Pab from Full-length Protein

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Search OriGene for S1PR2

Tocris compounds for S1PR2

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for S1PR2

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S1PR2 Gene

protein-coding GIFtS: 51

Aliases &
Descriptions
for S1PR2

Summaries
for S1PR2

Genomic Location
for S1PR2

Proteins
for S1PR2

Protein Domains/
Families
for S1PR2

Gene Function
for S1PR2

Pathways & Interactions
for S1PR2

Drugs & Compounds
for S1PR2

Transcripts
for S1PR2

Expression
for S1PR2

Orthologs
for S1PR2

Paralogs
for S1PR2

SNPs/Variants
for S1PR2

Disorders & Mutations
for S1PR2

Medical News
for S1PR2

Publications
for S1PR2

Search for S1PR2

Genome Databases showing S1PR2

Other Databases showing S1PR2

Specialized Databases showing S1PR2

Licensable Technologies
for S1PR2

Services
for S1PR2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

S1PR2 Gene

protein-coding GIFtS: 51

Aliases & Descriptionsfor S1PR2

Summariesfor S1PR2

Genomic Locationfor S1PR2

Proteinsfor S1PR2

Protein Domains/Familiesfor S1PR2

Gene Functionfor S1PR2

Pathways & Interactionsfor S1PR2

Drugs & Compoundsfor S1PR2

Transcriptsfor S1PR2

Expression for S1PR2

Orthologsfor S1PR2

Paralogsfor S1PR2

SNPs/Variantsfor S1PR2

Disorders & Mutationsfor S1PR2

Medical Newsfor S1PR2

Publicationsfor S1PR2

Search for S1PR2

Genome Databases showing S1PR2

Other Databases showing S1PR2

Specialized Databases showing S1PR2

Licensable Technologiesfor S1PR2

Servicesfor S1PR2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for S1PR2

Summaries
for S1PR2

Genomic Location
for S1PR2

Proteins
for S1PR2

Protein Domains/
Families
for S1PR2

Gene Function
for S1PR2

Pathways & Interactions
for S1PR2

Drugs & Compounds
for S1PR2

Transcripts
for S1PR2

Expression
for S1PR2

Orthologs
for S1PR2

Paralogs
for S1PR2

SNPs/Variants
for S1PR2

Disorders & Mutations
for S1PR2

Medical News
for S1PR2

Publications
for S1PR2

Licensable Technologies
for S1PR2

Services
for S1PR2