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EDF1 Gene

protein-coding   GIFtS: 56

GC09M138876
endothelial differentiation-related factor 1
(Previous name: multiprotein bridging factor-1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    

Aliases &
Descriptions
for EDF1

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
EDF-1 1, 2, 3
MBF1 2, 3
MGC9058 2
OTTHUMP00000022616 2
OTTHUMP00000022617 2
Descriptions
Multiprotein-bridging factor 1 3
endothelial differentiation-related factor 1 2
multiprotein bridging factor 1 2
multiprotein bridging factor-1 1, 2
External Ids
HGNC: 31641
Entrez Gene: 87212
UniProtKB: O608693
Ensembl: ENSG000001072237
Search outside databases for aliases for EDF1 gene

Previous GC identifers: GC09M130979 GC09M131446 GC09M133197 GC09M135113 GC09M137032

Summaries
for EDF1

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for EDF1:
This gene encodes a protein that may regulate endothelial cell differentiation. It has been
postulated that the protein functions as a bridging molecule that interconnects regulatory
proteins and the basal transcriptional machinery, thereby modulating the transcription of genes
involved in endothelial differentiation. This protein has also been found to act as a
transcriptional coactivator by interconnecting the general transcription factor TATA
element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts
which encode distinct proteins have been found for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: EDF1_HUMAN, O60869
Function: Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG
transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1.
Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May
function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and
lipid metabolism

Gene Wiki entry for EDF1

Genomic Location
for EDF1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the EDF1 gene  

Entrez Gene cytogenetic band: 9q34.3   Ensembl cytogenetic band:  9q34.3   HGNC cytogenetic band: 9q34.3

EDF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M138876:     (about GC identifiers)

Start:
 138,876,392 bp from pter
End:
 138,880,559 bp from pter
Size:
 4,168 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000009.10  NT_024000.16  

Proteins
for EDF1

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: EDF1_HUMAN, O60869 (See protein sequence)
Recommended Name: Endothelial differentiation-related factor 1  
Size: 148 amino acids; 16369 Da
Subunit: Interacts with TBP and the transcription factor IID (TFIID) complex, NR5A2, NR1H3 and
PPARG. Interaction with TBP is regulated by phosphorylation. Binds NR5A1, ATF1, FOS and JUN via
their conserved basic region. Binding to calmodulin is regulated by calcium and phosphorylation of
the IQ motif
Subcellular location: Cytoplasm. Nucleus. Note=Also nuclear upon binding to NR5A1 and treatment of
cells with TPA or forskolin
Developmental stage: Expressed in fetal tissues. More abundant in kidney
Sequence caution: Sequence=CAI12698.1; Type=Erroneous gene model prediction;
PDB structures from and Proteopedia :
1X57 (3D)    
Secondary accessions: Q5T5T2 Q9UIM1
Alternative splicing: 2 isoforms:  O60869-1   O60869-2   

Post-translational modifications:

  • Phosphorylated (by PKA and PKC)1
  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (2 alternative transcripts): 
    NP_003783.1  NP_694880.1  


    ENSEMBL proteins: 
    ENSP00000224073 ENSP00000360712 ENSP00000360711 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (EDF1)
    Human Recombinant Proteins from Abnova (EDF1)
                  OriGene Purified Recombinant Human Protein: EDF1 

    4 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622 intracellular TAS9813014
    GO:0005634 nucleus NAS8164657
    GO:0005669colocalizes with transcription factor TFIID complex IDA12040021
    GO:0005737 cytoplasm IDA10567391
    About this table

    Antibodies for EDF1: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for EDF1
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (EDF1), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (EDF1)
    Novus Biologicals Antibodies for EDF1

    Assays for EDF1: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for EDF1

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro domains/families:
     IPR001387 HTH_3
     IPR013729 MBF1_N


       GeneDecks  EDF1 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry O60869

    ProtoNet protein and cluster: O60869

    1 Blocks protein family: IPB013729 Multiprotein bridging factor 1

    UniProtKB/Swiss-Prot: EDF1_HUMAN, O60869
    Domain: The IQ motif, which is involved in calmodulin binding, overlaps with the binding domain for
    nuclear receptors and transcription factors. Its phosphorylation probably allows a switch between
    the two activities of the protein (By similarity)
    Similarity: Contains 1 HTH cro/C1-type DNA-binding domain

    Gene Function
    for EDF1

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (EDF1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (EDF1)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_153200

                  Applied Biosystems Silencer® siRNAs for EDF1

                  Sigma-Aldrich siRNA for EDF1  
                         Sigma-Aldrich shRNA for EDF1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for EDF1
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_003792
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_003792
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_003792 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_003792

    UniProtKB/Swiss-Prot: EDF1_HUMAN, O60869
    Function: Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG
    transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1.
    Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May
    function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and
    lipid metabolism
    Induction: Down-regulated by HIV type I protein TAT or phorbol ester (TPA) treatment in endothelial
    cells (at mRNA and protein levels)

    5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700NOT transcription factor activity IMP12040021
    GO:0003713 transcription coactivator activity IMP10567391 12040021
    GO:0004402NOT histone acetyltransferase activity IDA12040021
    GO:0005516 calmodulin binding IEA--
    GO:0008168NOT methyltransferase activity IDA12040021
    About this table

    Pathways & Interactions
    for EDF1

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    5/7 Sigma-Aldrich "Your Favorite Gene" Pathways for  EDF1  (Your Favorite Gene powered by Ingenuity) (see all 7 ) 
     Ubiquinone Biosynthesis
     Selenoamino Acid Metabolism
     Aminophosphonate Metabolism
     Tryptophan Metabolism
     Tyrosine Metabolism

       GeneDecks  EDF1 for the pathways selected above  
    About GeneDecksing

     Gene Network CentralTM Interacting Genes and Proteins Network for  EDF1 


    5/81 Interacting proteins for EDF1 (O608691 ENSP000002240733) via UniProtKB, MINT, and/or STRING (see all 81 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TBPP202261, ENSP000002303543EBI-781315, EBI-355371 STRING (score=.999)
    NR5A2O004821, ENSP000003563313EBI-781301, EBI-781320 STRING (score=.895)
    NR1H3Q131331, ENSP000003424703EBI-781301, EBI-781356 STRING (score=.783)
    ATF1P188461EBI-781310, EBI-852794
    FOSP011001EBI-781310, EBI-852851
    About this table

    5 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355 regulation of transcription, DNA-dependent TAS8164657
    GO:0007275 multicellular organismal development TAS9813014
    GO:0019216 regulation of lipid metabolic process TAS12040021
    GO:0043388 positive regulation of DNA binding IDA10567391
    GO:0045446 endothelial cell differentiation TAS12040021
    About this table

    Drugs & Compounds
    for EDF1

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for EDF1
    2 Novoseek chemical compound relationships for EDF1 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    leucine 35.85 1 10567391 (1)
    nitric oxide 0.00 1 16055206 (1)
    About this table


    Transcripts
    for EDF1

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (EDF1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (EDF1)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_153200

                  Sigma-Aldrich siRNA for EDF1  
                         Sigma-Aldrich shRNA for EDF1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_003792  NM_153200  

    REFSEQ mRNAs for EDF1 gene (2 alternative transcripts): 

    NM_003792.2   NM_153200.1   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_003792  NM_153200  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_003792
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_003792
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_003792 

    Additional cDNA sequence: 

    AB002282.1 AB002283.2 BC015500.1 BT009863.1 CR541914.1 

    14 DOTS entries:

    DT.100885943  DT.455909  DT.92440628  DT.95366227  DT.95366228  DT.100802225  DT.92440626  DT.95366237 
    DT.100058114  DT.121158512  DT.121158524  DT.95366229  DT.95366234  DT.95366240 

    24/360 AceView cDNA sequences (see all 360 ):

    CA448839 CD556359 BI755767 BM760376 AA325418 AI298210 BM760564 AI879231 
    F25098 BM968045 BC015500 BG575401 BU625866 BM914947 BG743000 BF000007 
    BM423594 NM_153200 BM713611 AJ707618 AW629804 BE794038 BM842802 BI766778 

    highest scoring ESTs for EDF1:

    AA927726 AB002282 AB002283 AW629804 BC015500 BE019633 BE019665 BE787775 BF342048 BG325691 

    Unigene Cluster for EDF1:

    Endothelial differentiation-related factor 1
    Hs.174050  [show with all ESTs]
    Unigene Representative Sequence: BE791300


    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for EDF1

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6
    SP1:                                      -     -         
    SP2:                                      -               
    SP3:                                                      

    About this scheme

    ECgene alternative splicing isoforms for EDF1

    3 Ensembl transcripts including schematic representations:
    ENST00000224073  ENST00000371649  ENST00000371648  

    Expression
    for EDF1

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    EDF1 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for EDF1

    1 / 2 / 3

    4 probe-sets matching EDF1 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    		209059_s_at2, 3 U133-A 1 1.00 1.00 -- -- AB002282 0.80 1.00 0.91 1

    		209058_at2, 3 U133-A 1 1.00 1.00 -- -- AB002282 0.80 1.00 0.91 1

    		209059_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    		209058_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: ACAGGGTGAC

    SOURCE GeneReport for Unigene cluster: Hs.174050

    UniProtKB/Swiss-Prot: EDF1_HUMAN, O60869
    Tissue specificity: Expressed in brain, liver, lung, kidney and heart (at protein level).
    Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues

    Orthologs
    for EDF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for EDF1 gene from 5/20 species (see all 20 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 EDF11   -- endothelial differentiation-related factor 1 90.99(n)
    100(a)    		 480674  XM_537793.2  XP_537793.2 
    chimpanzee
    (Pan troglodytes)    		 EDF11   -- endothelial differentiation-related factor 1 94.05(n)
    90.71(a)    		 748763  XM_001163031.1  XP_001163031.1 
    cow
    (Bos taurus)    		 EDF11   -- endothelial differentiation-related factor 1 89.86(n)
    100(a)    		 515380  NM_001035307.1  NP_001030384.1 
    rat
    (Rattus norvegicus)    		 Edf11   -- endothelial differentiation-related factor 1 88.74(n)
    98.65(a)    		 296570  XM_215993.3  XP_215993.2 
    mouse
    (Mus musculus)    		 Edf11, 5 25
    		 endothelial differentiation-related factor 11, 5 88.96(n)1
    98.65(a)1    		 590221  NM_021519.11  NP_067494.11 
     AA4094255  AA4094265  (see all 13)
    About this table        Species with no ortholog for EDF1

    ENSEMBL Gene Tree for EDF1

    Paralogs
    for EDF1

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    		  --

    SNPs/Variants
    for EDF1

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/20 NCBI SNPs in EDF1 are shown (see all 20 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 19)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 9 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs9453851,2
    		A,C,F,H138876298(-) AGTAGT/CGGTTG 1 -- ng5113Minor allele frequency- C:0.18EU EA WA NA 1156
    --
    rs115499461,2
    		H138877629(-) TGACCC/ATGGAG 2 M/L mis1 ese34Minor allele frequency- A:0.00EU EA WA 402
    --
    rs48801471,2
    		A138880995(+) CGCTCC/GAGGAC 2 -- ng310--------
    --
    rs70372051,2
    		A,C138880080(+) cccacC/Gaacag 2 -- int10--------
    --
    rs70252381,2
    		A,C138880252(+) CccctA/Gtcctg 2 -- int10--------
    --
    rs107815171,2
    		C138879862(+) CCACCC/TTCATC 2 -- int10--------
    --
    rs735642761,2
    		--138877154(+) GGACCC/TGGCGA 2 R/Q mis1 int10--------
    --
    rs108701331,2
    		--138880738(+) AGGGAA/GGGCGA 2 -- ng310--------
    rs10589741,2
    		--138876693(-) GGGAAG/AATGTT 2 -- int1 ng511Minor allele frequency- A:0.00MN 184
    --
    rs48801481,2
    		--138881085(+) GCTCTA/GTCGCC 2 -- ng310--------
    About this table

    HapMap Linkage Disequilibrium images for EDF1 (up to first 250kb)

    Disorders & Mutations
    for EDF1

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 605107

    Medical News
    for EDF1

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for EDF1

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/27 PubMed articles for EDF1 gene (see all 27 ):

    Search for EDF1

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing EDF1

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 8721 HGNC: 3164 AceView: EDF1 Ensembl:ENSG00000107223 euGenes: HUgn8721
    ECgene: EDF1 H-InvDB: EDF1

    Other Databases showing EDF1

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing EDF1

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for EDF1 Genetics and Cytogenetics in Oncology and Haematology

    Licensable Technologies
    for EDF1

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for EDF1

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for EDF1:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
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      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for EDF1-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for EDF1 Antibodies for EDF1
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for EDF1 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
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     Cell Culture Products   ELISAs  
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     Recombinant & Natural Proteins  

     Recombinant Proteins (EDF1)
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     Search for Antibodies & Assays

     Recombinant Proteins
    (EDF1)
     Antibodies (EDF1)
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     Search Tocris compounds for EDF1




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for EDF1

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