EDEM1 Gene
protein-coding GIFtS: 57
GCID: GC03P005203
|
|
ER degradation enhancer, mannosidase alpha-like 1
| |
Aliases
for EDEM1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ER Degradation Enhancer, Mannosidase Alpha-Like 11 2 | | EDEM1 2 3 5 | | KIAA02121 3 5 | | ER Degradation-Enhancing Alpha-Mannosidase-Like 12 | | ER Degradation-Enhancing Alpha-Mannosidase-Like Protein 12 |
Export aliases for EDEM1 gene to outside databasesPrevious GC identifers: GC03P005221 GC03P005204 |
Summaries
for EDEM1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: EDEM1_HUMAN, Q92611Function: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexincycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfoldedglycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It lacksmannosidase activity
Gene Wiki entry for EDEM1
|
Genomic Views
for EDEM1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the EDEM1 gene promoter:
SRF Brachyury SRF (504 AA) AP-2gamma Evi-1 GATA-1 FOXL1 POU2F1 POU2F1a FOXO4
Other transcription factors
Search SABiosciences Chromatin IP Primers for EDEM1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat EDEM1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p26.1 Ensembl cytogenetic band: 3p26.1 HGNC cytogenetic band: 3p26.1EDEM1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P005203: view genomic region
(about GC identifiers)
Start:
|
5,229,331 bp from pter |
End:
|
5,261,650 bp from pter |
Size:
|
32,320 bases |
Orientation:
|
plus strand |
|
Proteins
for EDEM1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: EDEM1_HUMAN, Q92611 (See
protein sequence)Recommended Name: ER degradation-enhancing alpha-mannosidase-like protein 1 Size: 657 amino acids; 73768 Da
Subunit: Interacts with DERL2 and DERL3. Binds to SEL1L
Subcellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein
Sequence caution: Sequence=BAA13203.2; Type=Erroneous initiation;
Secondary accessions: A8K9C8Explore the universe of human proteins at neXtProt for EDEM1: NX_Q92611
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q92611
EDEM1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055489.1
ENSEMBL proteins: ENSP00000393659 ENSP00000256497 ENSP00000394615 ENSP00000394099 Reactome Protein details: Q92611
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005789 | endoplasmic reticulum membrane |
TAS | -- | | GO:0016020 | membrane |
-- | -- | | GO:0030176 | integral to endoplasmic reticulum membrane |
ISS | -- |
EDEM1 for ontologies About GeneDecksing
EDEM1 Antibody Products:
Assay Products for EDEM1: |
Protein
Domains /
Families
for EDEM1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
EDEM1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q92611ProtoNet protein and cluster: Q92611 1 Blocks protein family: IPB001382 Glycosyl hydrolase family 47 signature
UniProtKB/Swiss-Prot: EDEM1_HUMAN, Q92611Similarity: Belongs to the glycosyl hydrolase 47 family |
Function
for EDEM1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: EDEM1_HUMAN, Q92611Function: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexincycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfoldedglycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It lacksmannosidase activity
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for EDEM1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for EDEM1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: EDEM1 (NM_014674) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for EDEM1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EDEM1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EDEM1 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
EDEM1 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Edem1tm1Lex for EDEM1
1 MGI phenotypic allele  for Edem1 (no phenotypes)
EDEM1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for EDEM1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Calnexin/calreticulin cycle | | | 2 | Asparagine N-linked glycosylation | | | 3 | Activation of Chaperone Genes by XBP1(S) | | | 4 | Expression of EDEM | | | 5 | Protein processing in endoplasmic reticulum | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  GeneGo (Thomson Reuters) Pathway for EDEM1
5/10 
Reactome Pathways for EDEM1 (see all 10)
1 
Kegg Pathway (Kegg details for EDEM1):
EDEM1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for EDEM1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/26 Interacting proteins for EDEM1 (Q926111, 2, 3 ENSP000002564974) via UniProtKB, MINT, STRING, and/or I2D (see all 26)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006457 | protein folding |
TAS | -- | | GO:0006987 | activation of signaling protein activity involved in unfolded protein response |
TAS | -- | | GO:0018279 | protein N-linked glycosylation via asparagine |
TAS | -- | | GO:0030433 | ER-associated protein catabolic process |
ISS | -- | | GO:0030968 | endoplasmic reticulum unfolded protein response |
TAS | -- |
EDEM1 for ontologies About GeneDecksing
|
Drugs & Compounds
for EDEM1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
EDEM1 for compounds About GeneDecksing
 Browse Tocris compounds for EDEM1
1 Novoseek chemical compound relationship for EDEM1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| mannose |
60.7 |
2 |
19934218 (1) |
Search CenterWatch for drugs/clinical trials and news about EDEM1
|
Transcripts
for EDEM1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for EDEM1 gene: NM_014674.2 Unigene Cluster for EDEM1: ER degradation enhancer, mannosidase alpha-like 1 Hs.224616 [show with all ESTs]Unigene Representative Sequence: NM_0146747 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000434243 ENST00000256497(uc011asz.1 uc003bqi.3) ENST00000465369
ENST00000443790 ENST00000465187 ENST00000445686(uc021wsl.1) ENST00000492751
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for EDEM1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for EDEM1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: EDEM1 (NM_014674) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for EDEM1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EDEM1 |
Additional cDNA sequence: AK292643.1 AK298511.1 AK302065.1 BC019088.1 D86967.1 11 DOTS entries: DT.95370360 DT.120888966 DT.99938746 DT.100785750 DT.120888904 DT.120888929 DT.92045737 DT.95365988 DT.120888884 DT.91878434 DT.92462892 24/152 AceView cDNA sequences (see all 152): BU618490 AI142424 BF511061 BU623214 AA287304 CK904356 CR621147 AA258630 BC019088 BX352520 BU621704 AA250852 BX956626 CD246059 BG255753 CB135001 N32546 BG057331 BM542988 AA369222 AA290653 AI193245 CR597249 AA885205
GeneLoc Exon Structure
|
Expression
for EDEM1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| EDEM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGACATTCCT
About this image
See EDEM1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for EDEM1
SOURCE GeneReport for Unigene cluster: Hs.224616
SABiosciences Expression via Pathway-Focused PCR Arrays including EDEM1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for EDEM1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat EDEM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat EDEM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat EDEM1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EDEM1 |
Orthologs
for EDEM1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for EDEM1 gene from 7/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
EDEM11 |
ER degradation enhancer, mannosidase alpha-like 1 |
78.05(n)
84.07(a) |
|
416110 NM_001006143.1 NP_001006143.1 |
lizard
(Anolis carolinensis) |
Reptilia |
EDEM16 |
-- |
81(a) |
1 ↔ 1 |
2(172875305-172896858) |
African clawed frog
(Xenopus laevis) |
Amphibia |
CA972604.12 |
-- |
77.6(n) |
|
CA972604.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc558162 |
similar to ER degradation enhancing alpha mannosidase-like |
75.86(n) |
|
394164 BC045461.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
C47E12.31 |
Protein C47E12.3 |
56.3(n)
60.43(a) |
|
177857 NM_069401.3 NP_501802.2 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT1G275201 |
putative alpha-mannosidase I MNS5 |
51.93(n)
46.25(a) |
|
839643 NM_102516.3 NP_564288.1 |
rice
(Oryza sativa) |
Liliopsida |
Os02g07413001 |
hypothetical protein |
50.42(n)
45.19(a) |
|
4330685 NM_001054615.1 NP_001048080.1 |
ENSEMBL Gene Tree for EDEM1 (if available)
TreeFam Gene Tree for EDEM1 (if available) |
Paralogs
for EDEM1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for EDEM1 gene
- EDEM22 EDEM32
3 SIMAP similar genes for EDEM1 using alignment to 4 protein entries: EDEM1_HUMAN (see all proteins):EDEM3 EDEM2 MAN1B1
EDEM1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for EDEM1
PGOHUM00000248769
|
Genomic Variants
for EDEM1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for EDEM1 (5229331 - 5261650 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for EDEM1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing EDEM1 |
|
Disorders
/ Diseases
for EDEM1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
EDEM1 for disorders About GeneDecksing
OMIM gene information: 607673
OMIM disorders: --
4  diseases for EDEM1: About MalaCardslong qt syndrome cytomegalovirus infection protein s deficiency neuroblastoma
Human Genome Epidemiology (HuGE) Navigator: EDEM1 (2 documents)
Export disorders for EDEM1 gene to outside databases
|
Publications
for EDEM1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for EDEM1 gene, integrated from 9 sources (see all 44):
(articles sorted by number of sources associating them with EDEM1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle. (PubMed id 12610306)1, 2, 3 Molinari M.... Paganetti P. (2003)
- A dual role for EDEM1 in the processing of rod opsin. (PubMed id 19934218)1, 2, 9 Kosmaoglou M.... Cheetham M.E. (2009)
- EDEM1 recognition and delivery of misfolded proteins to the SEL1L- containing ERAD complex. (PubMed id 19524542)1, 2 Cormier J.H.... Hebert D.N. (2009)
- Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. (PubMed id 16449189)1, 2 Oda Y.... Mori K. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)1, 2 Nagase T....Nomura N. (1996)
- EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded alpha1-antitrypsin. (PubMed id 16629899)1, 9 Hosokawa N....Nagata K. (2006)
- A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation. (PubMed id 11375934)1, 9 Hosokawa N....Nagata K. (2001)
- Tyrosinase degradation is prevented when EDEM1 lacks t he intrinsically disordered region. (PubMed id 22905195)1 Marin M.B....Petrescu S.M. (2012)
- Mannose trimming is required for delivery of a glycop rotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degrad ation steps. (PubMed id 21062743)1 Groisman B....Lederkremer G.Z. (2011)
|
External Searches for EDEM1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing EDEM1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing EDEM1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing EDEM1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for EDEM1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for EDEM1 gene:
Search GeneIP for patents involving EDEM1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for EDEM1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for EDEM1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for EDEM1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for EDEM1 | | | OriGene Protein Over-expression Lysate for EDEM1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for EDEM1 | | OriGene 3'-UTR Clone for EDEM1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for EDEM1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for EDEM1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for EDEM1 | | OriGene Custom Protein Services for EDEM1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat EDEM1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing EDEM1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat EDEM1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat EDEM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat EDEM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat EDEM1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for EDEM1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | EDEM1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EDEM1 |
|  |  |  | | | | Search ThermoFisher Antibodies for EDEM1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EDEM1 |
|
|
|
|
