Aliases for EDC3 Gene
External Ids for EDC3 Gene
Previous HGNC Symbols for EDC3 Gene
Previous GeneCards Identifiers for EDC3 Gene
This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability. [provided by RefSeq, May 2017]
GeneCards Summary for EDC3 Gene
EDC3 (Enhancer Of MRNA Decapping 3) is a Protein Coding gene. Diseases associated with EDC3 include Mental Retardation, Autosomal Recessive 50 and Autosomal Recessive Non-Syndromic Intellectual Disability. Among its related pathways are Deadenylation-dependent mRNA decay and Gene Expression. GO annotations related to this gene include identical protein binding and RNA binding.
UniProtKB/Swiss-Prot for EDC3 Gene
Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping. May play a role in spermiogenesis and oogenesis.