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EDARADD Gene

protein-coding GIFtS: 47

GC01P234691

EDAR-associated death domain
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
ED3 ^², ⁵
EDA3 ^², ⁵
OTTHUMP00000037857 ^²
OTTHUMP00000037858 ^²

Descriptions
Crinkled homolog ^², ³
EDAR-associated death domain ^²
EDAR-associated death domain protein ^², ³
ectodysplasia A receptor associated death domain ^²
ectodysplasin A receptor associated adapter protein ^²

External Ids
HGNC: 14341¹
Entrez Gene: 128178²
UniProtKB: Q8WWZ3³
Ensembl: ENSG00000186197⁷

Search outside databases for aliases for EDARADD gene

Previous GC identifers: GC01P232012 GC01P232808 GC01P233598 GC01P232884 GC01P232885

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for EDARADD:

This gene was identified by its association with ectodermal dysplasia, a genetic disorder

characterized by defective development of hair, teeth, and eccrine sweat glands. The protein

encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a

death domain receptor known to be required for the development of hair, teeth and other ectodermal

derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of

hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and

links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants

of this gene encoding distinct isoforms have been reported. [provided by RefSeq]

UniProtKB/Swiss-Prot: EDAD_HUMAN, Q8WWZ3

Function: Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA

signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B

Gene Wiki entry for EDARADD

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the EDARADD gene

Entrez Gene cytogenetic band: 1q43 Ensembl cytogenetic band: 1q43 HGNC cytogenetic band: 1q42.3

EDARADD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P234691: (about GC identifiers)

Start:	234,624,303 bp from pter
End:	234,714,631 bp from pter
Size:	90,329 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000001.9 NT_004836.17

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: EDAD_HUMAN, Q8WWZ3 (See protein sequence)

Recommended Name: Ectodysplasin-A receptor-associated adapter protein

Size: 215 amino acids; 24802 Da

Subunit: Self-associates and binds EDAR, TRAF1, TRAF2 and TRAF3

Subcellular location: Cytoplasm (Probable)

Secondary accessions: B1AL54 Q5VYJ7

Alternative splicing: 2 isoforms: Q8WWZ3-1 Q8WWZ3-2

REFSEQ proteins (2 alternative transcripts):

NP_542776.1 NP_665860.2

ENSEMBL proteins:

ENSP00000335076 ENSP00000355546

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
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	Browse Abnova for Human Recombinant Proteins

OriGene Purified Recombinant Human Protein: EDARADD

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--

About this table

Antibodies for EDARADD:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for EDARADD
	Browse R&D Systems for Antibodies
	Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for EDARADD

Assays for EDARADD:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q8WWZ3

ProtoNet protein and cluster: Q8WWZ3

1 Blocks protein family: IPB000488 Death domain

UniProtKB/Swiss-Prot: EDAD_HUMAN, Q8WWZ3

Similarity: Contains 1 death domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EDARADD)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_145861

Applied Biosystems Silencer® siRNAs for EDARADD

Sigma-Aldrich siRNA for EDARADD

Sigma-Aldrich shRNA for EDARADD

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_080738
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_080738
untagged cDNA clones in CMV expression vector (see all 2): NM_080738

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_145861

UniProtKB/Swiss-Prot: EDAD_HUMAN, Q8WWZ3

Function: Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA

signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B

15 MGI mutant phenotypes (inferred from 5 alleles) (MGI details for Edaradd):

behavior/neurological	craniofacial	endocrine/exocrine gland	growth/size	hearing/vestibular/ear
homeostasis/metabolism	lethality-postnatal	life span-post-weaning/aging	limbs/digits/tail	nervous system
pigmentation	reproductive system	respiratory system	skin/coat/nails	vision/eye

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	ISS	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for EDARADD

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007165	signal transduction	IEA	--
GO:0007249	I-kappaB kinase/NF-kappaB cascade	ISS	11780064
GO:0007275	multicellular organismal development	IEA	--
GO:0030154	cell differentiation	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for EDARADD

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EDARADD)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_145861

Sigma-Aldrich siRNA for EDARADD

Sigma-Aldrich shRNA for EDARADD

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_080738 NM_145861

REFSEQ mRNAs for EDARADD gene (2 alternative transcripts):

NM_080738.3 NM_145861.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_080738 NM_145861

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_080738
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_080738
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_080738

Additional cDNA sequence:

AK096339.1 AK290862.1 AK291930.1 AK314634.1 AY028913.1 AY028914.1 AY071862.1 BC006533.2

BC114557.1 BC114560.1 BC128082.1

24/32 DOTS entries (see all 32 ):

DT.40269519 DT.100044212 DT.100734628 DT.100662717 DT.100734719 DT.95167954 DT.95167955 DT.100734673

DT.92386651 DT.92472726 DT.100642965 DT.100734610 DT.121397993 DT.92393969 DT.92472596 DT.92472607

DT.95167907 DT.97857337 DT.97863410 DT.99990205 DT.100060472 DT.100734602 DT.100734605 DT.100734614

24/37 AceView cDNA sequences (see all 37 ):

NM_080738 CA841301 AI140628 AL705374 BX109179 AY071862 BQ436003 BG679812

BE294841 AY028914 AW245779 BG120587 CA843003 NM_145861 BQ631337 AI096404

BQ959390 BE904884 AK096339 BC006533 CB123098 BC046928 CD516461 AY028913

highest scoring ESTs for EDARADD:

AY028913 AY028914 BE141737 BE392512 BE904884 BG260205 BQ631615 BQ959390 CA842490 CB123098

Unigene Cluster for EDARADD:

EDAR-associated death domain

Hs.352224 [show with all ESTs]

Unigene Representative Sequence: NM_080738

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000334232 ENST00000366587

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

EDARADD expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for EDARADD

¹ / ²

1 probe-set matching EDARADD gene

	Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
	Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
	1553430_a_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GTGCCTCATC

SOURCE GeneReport for Unigene cluster: Hs.352224
UniProtKB/Swiss-Prot: EDAD_HUMAN, Q8WWZ3
Tissue specificity: Detected in adult pancreas, placenta and fetal skin, and at lower levels in
lung, thymus, prostate and testis

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for EDARADD gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	EDARADD¹	--	EDAR-associated death domain	87.46(n) 87.13(a)	607372 XM_844008.1 XP_849101.1
chimpanzee (Pan troglodytes)	EDARADD¹	--	EDAR-associated death domain	97.17(n) 97.17(a)	457841 XM_514291.2 XP_514291.2
rat (Rattus norvegicus)	Edaradd¹	--	EDAR-associated death domain	81.46(n) 83.67(a)	498769 XM_574055.2 XP_574055.2
mouse (Mus musculus)	Edaradd^{1, 5}	13 (6.00 cM)⁵	EDAR (ectodysplasin-A receptor)-associated death domain^{1, 5}	82.06(n)¹ 80.71(a)¹	171211¹ NM_133643.3¹ NP_598398.3¹ AF358671⁵ AK018047⁵ (see all 13)
chicken (Gallus gallus)	EDARADD¹	--	EDAR-associated death domain	70.65(n) 66.3(a)	497625 NM_001012405.2 NP_001012405.2

About this table Species with no ortholog for EDARADD

ENSEMBL Gene Tree for EDARADD

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/816 NCBI SNPs in EDARADD are shown (see all 816 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 205)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs966365^1,2	A,C,F,H,O	234624394(-)	`CTCCCT/CATCTG`	2	I/M	mis¹ ng5¹ ese³		16		NA EA MN EU WA	1682
	rs7513402^1,2	A,C,F,H	234714134(+)	`CGCTCT/CGTGAC`	2	--	ut3¹		4		EU EA WA	412
	rs10802533^1,2	A,C,F,H	234624035(+)	`CTTTAG/TAGCAA`	2	--	ng5¹		4		EU EA WA	416
	rs966364^1,2	A,C,F,H	234624551(-)	`AAAGTT/CGGGTC`	2	--	ng5¹ int¹		4		EU EA WA	416
--	rs3916983^1,2	A,C,F,H	234714173(-)	`CCATTG/CGCCTG`	2	--	ut3¹ ese³		4		NA EA WA	778
	rs10925115^1,2	C,F,H	234622315(+)	`GATCAT/CAGCTC`	1	--	ng5¹		8		EU EA WA	830
--	rs7520978^1,2	A,C	234623510(+)	`cggtgA/Gggttt`	2	--	ng5¹		0	--	--	--	--
--	rs7555630^1,2	A,C	234623412(+)	`ctcccA/Gggttc`	2	--	ng5¹		0	--	--	--	--
	rs6428955^1,2	A,C	234714359(+)	`TTTGCC/TGGCAG`	2	--	ut3¹ ese³		0	--	--	--	--
--	rs4659667^1,2	A,C	234622781(+)	`agagaC/Tggggt`	1	--	ng5¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for EDARADD (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 606603 disorders: 224900 129490

UniProtKB/Swiss-Prot: EDAD_HUMAN, Q8WWZ3

Defects in EDARADD are a cause of ectodermal dysplasia anhidrotic (EDA) [MIM:224900]; also

known ectodermal dysplasia hypohidrotic autosomal recessive (HED). Ectodermal dysplasia defines a

heterogeneous group of disorders due to abnormal development of two or more ectodermal structures.

EDA is characterized by sparse hair (atrichosis or hypotrichosis), abnormal or missing teeth and

the inability to sweat due to the absence of sweat glands

3 Novoseek disease relationships for EDARADD gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
ectodermal dysplasia, hypohidrotic	93.52	1	17354266 (1)
necrosis	18.90	1	15973734 (1)
tumors	0.00	1	15973734 (1)

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GeneTests: EDARADD

Hypohidrotic Ectodermal Dysplasia

Human Gene Mutation Database: EDARADD

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/18 PubMed articles for EDARADD gene (see all 18 ):

Gene defect in ectodermal dysplasia implicates a DEATH domain adapter in development. (PubMed id 11780064)^{2, 3, 4} Headon D.J.... Overbeek P.A. (2001)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{3, 4} Gregory S.G.... Bentley D.R. (2006)
Identification of a novel DEATH domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice. (PubMed id 11882293)^{3, 4} Yan M....Dixit V.M. (2002)
Autosomal dominant anhidrotic ectodermal dysplasias at the EDARADD locus. (PubMed id 17354266)^{1, 4} Bal E....Smahi A. (2007)
Mutation screening of the Ectodysplasin-A receptor gene EDAR in hypohidrotic ectodermal dysplasia. (PubMed id 18231121)⁴ van der Hout A.H....van Essen A.J. (2008)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)³ Ota T....Sugano S. (2004)
Death receptor signaling giving life to ectodermal organs. (PubMed id 11997580)³ Thesleff I. and Mikkola M.L. (2002)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)
The ectodermal dysplasia receptor activates the nuclear factor- kappaB, JNK, and cell death pathways and binds to ectodysplasin A. (PubMed id 11035039)³ Kumar A.... Chaudhary P.M. (2001)
Definitive evidence for an autosomal recessive form of hypohidrotic ectodermal dysplasia clinically indistinguishable from the more common X-linked disorder. (PubMed id 9245989)³ Munoz F....Zonana J. (1997)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 128178	HGNC: 14341	AceView: EDARADD	Ensembl:ENSG00000186197	euGenes: HUgn128178
ECgene: EDARADD	H-InvDB: EDARADD

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
GeneReviews	http://www.genetests.org/query?gene=EDARADD

Licensable Technologies for EDARADD
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for EDARADD:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for EDARADD-related products

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EDARADD Gene

protein-coding GIFtS: 47

Aliases &
Descriptions
for EDARADD

Summaries
for EDARADD

Genomic Location
for EDARADD

Proteins
for EDARADD

Protein Domains/
Families
for EDARADD

Gene Function
for EDARADD

Pathways & Interactions
for EDARADD

Drugs & Compounds
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Transcripts
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Expression
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Orthologs
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Disorders & Mutations
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Medical News
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Genome Databases showing EDARADD

Other Databases showing EDARADD

Specialized Databases showing EDARADD

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

EDARADD Gene

protein-coding GIFtS: 47

Aliases & Descriptionsfor EDARADD

Summariesfor EDARADD

Genomic Locationfor EDARADD

Proteinsfor EDARADD

Protein Domains/Familiesfor EDARADD

Gene Functionfor EDARADD

Pathways & Interactionsfor EDARADD

Drugs & Compoundsfor EDARADD

Transcriptsfor EDARADD

Expression for EDARADD

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Disorders & Mutationsfor EDARADD

Medical Newsfor EDARADD

Publicationsfor EDARADD

Search for EDARADD

Genome Databases showing EDARADD

Other Databases showing EDARADD

Specialized Databases showing EDARADD

Licensable Technologiesfor EDARADD

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for EDARADD

Summaries
for EDARADD

Genomic Location
for EDARADD

Proteins
for EDARADD

Protein Domains/
Families
for EDARADD

Gene Function
for EDARADD

Pathways & Interactions
for EDARADD

Drugs & Compounds
for EDARADD

Transcripts
for EDARADD

Expression
for EDARADD

Orthologs
for EDARADD

Paralogs
for EDARADD

SNPs/Variants
for EDARADD

Disorders & Mutations
for EDARADD

Medical News
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