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Aliases &
Descriptions
for ECT2L
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| C6orf91 2, 3 | | ECT2-like 2 | | LFDH 2 | | OTTHUMP00000017301 2 | | dJ509I19.2 1, 2 | | dJ509I19.3 1, 2 | | dJ509I19.5 1, 2 |
| | | Descriptions |
|---|
| Lung-specific F-box and DH domain-containing protein 3 | | chromosome 6 open reading frame 91 1 | | epithelial cell transforming sequence 2 oncogene-like 2 | | lung specific F-box and DH domain containing protein 2 |
|
| |
Search outside databases for aliases for ECT2L genePrevious GC identifers: GC00U914183 GC06U900635 |
Summaries
for ECT2L(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: LFDH_HUMAN, Q008S8Function: May act as a guanine nucleotide exchange factor (GEF) (By similarity) |
Genomic Location
for ECT2L
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q24.1 Ensembl cytogenetic band: 6q24.1 HGNC cytogenetic band: 6q24.1ECT2L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P139158:
(about GC identifiers)
Start:
|
139,158,950 bp from pter |
End:
|
139,266,900 bp from pter |
Size:
|
107,951 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000006.10 NT_025741.14
| Proteins
for ECT2L
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: LFDH_HUMAN, Q008S8 (See
protein sequence)Recommended Name: Putative guanine nucleotide exchange factor LFDH Size: 904 amino acids; 104880 Da
Sequence caution: Sequence=CAI42868.2; Type=Erroneous gene model prediction; Sequence=CAI42870.1;
Type=Erroneous gene model prediction; Sequence=CAI42871.1; Type=Erroneous gene model prediction;
Secondary accessions: B2RUV6 Q5JWK2 Q5JWK3 Q5JWK4REFSEQ proteins: NP_001071174.1
ENSEMBL proteins: ENSP00000356655 ENSP00000385187
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
1 Gene Ontology (GO) cellular component term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005622 | intracellular |
IEA | -- |
About this table
Antibodies for ECT2L:
Assays for ECT2L: | Protein
Domains/
Families
for ECT2L(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q008S8
ProtoNet protein and cluster: Q008S8 1 Blocks protein family: IPB000219 DH domain
UniProtKB/Swiss-Prot: LFDH_HUMAN, Q008S8Similarity: Contains 1 DH (DBL-homology) domainSimilarity: Contains 1 F-box domain | Gene Function
for ECT2L
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| Browse Origene for 29mer shRNA kit in GFP-retroviral vector
 Applied Biosystems Silencer® siRNAs for ECT2L
 Sigma-Aldrich siRNA for ECT2L
Browse shRNA at Sigma-Aldrich
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001077706
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001077706
untagged cDNA clone in CMV expression vector: NM_001077706
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_001077706
UniProtKB/Swiss-Prot: LFDH_HUMAN, Q008S8Function: May act as a guanine nucleotide exchange factor (GEF) (By similarity)2 Gene Ontology (GO) molecular function terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005085 | guanyl-nucleotide exchange factor activity |
IEA | -- | | GO:0005089 | Rho guanyl-nucleotide exchange factor activity |
IEA | -- |
About this table | Pathways & Interactions
for ECT2L
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
--1 Gene Ontology (GO) biological process term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0035023 | regulation of Rho protein signal transduction |
IEA | -- |
About this table
|
Drugs & Compounds
for ECT2L(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ECT2L
|
Transcripts
for ECT2L(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| Browse Origene for 29mer shRNA kit in GFP-retroviral vector
Sigma-Aldrich siRNA for ECT2L
Browse shRNA at Sigma-Aldrich
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_001077706 REFSEQ mRNAs for ECT2L gene: NM_001077706.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001077706
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001077706
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001077706
untagged cDNA clone in CMV expression vector: NM_001077706
Additional cDNA sequence: AK304425.1 BC146884.1 DQ904331.1 4 DOTS entries: DT.204817 DT.97774071 DT.100664298 DT.121389463 1 AceView cDNA sequence:BM978455 Unigene Cluster for ECT2L: Epithelial cell transforming sequence 2 oncogene-like Hs.660603 [show with all ESTs]Unigene Representative Sequence: NM_001077706
GeneLoc Exon Structure
2 Ensembl transcripts including schematic representations: ENST00000367682
ENST00000401414
|
Expression
for ECT2L
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| ECT2L expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for ECT2L
1 Data from GNF BioGPS
About these images
About these images
CGAP SAGE TAG: GATGATGAGA
SOURCE GeneReport for Unigene cluster: Hs.660603
|
Orthologs
for ECT2L
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ECT2L gene from 2 species
About this table Species with no ortholog for ECT2L
ENSEMBL Gene Tree for ECT2L | Paralogs
for ECT2L(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for ECT2L gene
- FBXO162
|
SNPs/Variants
for ECT2L(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for ECT2L (up to first 250kb)
|
Disorders & Mutations
for ECT2L
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News
for ECT2L(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ECT2L (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 4 PubMed articles for ECT2L gene: |
Search for ECT2L
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ECT2L
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing ECT2L
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ECT2L(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for ECT2L(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for ECT2L:
 | |
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