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ECT2 Gene

protein-coding GIFtS: 60

GC03P173951

epithelial cell transforming sequence 2 oncogene
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
FLJ10461 ^²
MGC138291 ^²

Descriptions
Epithelial cell-transforming sequence 2 oncogene ^³
epithelial cell transforming sequence 2 oncogene ^²
epithelial cell transforming sequence 2 oncogene protein ^²

External Ids
HGNC: 3155¹
Entrez Gene: 1894²
UniProtKB: Q9H8V3³
Ensembl: ENSG00000114346⁷

Search outside databases for aliases for ECT2 gene

Previous GC identifers: GC03P169518 GC03P173499 GC03P173870 GC03P173793 GC03P173773

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ECT2:

The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange

factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of

DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed

that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this

protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to

have an important role in the regulation of cytokinesis. [provided by RefSeq]

UniProtKB/Swiss-Prot: ECT2_HUMAN, Q9H8V3

Function: Binds highly specifically to RhoA, RhoC and Rac proteins, but does not appear to catalyze

guanine nucleotide exchange (By similarity)

Gene Wiki entry for ECT2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ECT2 gene

Entrez Gene cytogenetic band: 3q26.1-q26.2 Ensembl cytogenetic band: 3q26.31 HGNC cytogenetic band: 3q26.1-q26.2

ECT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03P173951: (about GC identifiers)

Start:	173,951,207 bp from pter
End:	174,021,957 bp from pter
Size:	70,751 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000003.10 NT_005612.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: ECT2_HUMAN, Q9H8V3 (See protein sequence)

Recommended Name: Protein ECT2

Size: 883 amino acids; 100051 Da

Subunit: Associates with RACGAP1 at anaphase and during cytokinesis

Caution: It is uncertain whether Met-1 or Met-146 is the initiator

Secondary accessions: Q2M269 Q9NSV8 Q9NVW9

Alternative splicing: 2 isoforms: Q9H8V3-1 Q9H8V3-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_060568.3

ENSEMBL proteins:

ENSP00000376457 ENSP00000232458

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Sigma-Aldrich CompoZr ZFN for ECT2
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (ECT2)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--

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Antibodies for ECT2:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ECT2
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (ECT2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ECT2)
	Novus Biologicals Antibody for ECT2

Assays for ECT2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q9H8V3

ProtoNet protein and cluster: Q9H8V3

3 Blocks protein families:

IPB000219 DH domain

IPB001357 BRCT domain

IPB001849 Pleckstrin-like

UniProtKB/Swiss-Prot: ECT2_HUMAN, Q9H8V3

Similarity: Contains 2 BRCT domains

Similarity: Contains 1 DH (DBL-homology) domain

Similarity: Contains 1 PH domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ECT2)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_018098

Applied Biosystems Silencer® siRNAs for ECT2

Sigma-Aldrich siRNA and siRNA Panels for ECT2

Sigma-Aldrich shRNA Panels and shRNA for ECT2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ECT2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_018098
Myc/DDK tagged cDNA clone in CMV expression vector: NM_018098
untagged cDNA clones in CMV expression vector (see all 2): NM_018098

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_018098

UniProtKB/Swiss-Prot: ECT2_HUMAN, Q9H8V3

Function: Binds highly specifically to RhoA, RhoC and Rac proteins, but does not appear to catalyze

guanine nucleotide exchange (By similarity)

Genatlas biochemistry entry for ECT2:

mouse Ect2 related proto-oncogene 2

2 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Ect2):

lethality-prenatal/perinatal

no phenotypic analysis

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004871	signal transducer activity	IMP	12761501
GO:0005085	guanyl-nucleotide exchange factor activity	IEA	--
GO:0005089	Rho guanyl-nucleotide exchange factor activity	IEA	--
GO:0005515	protein binding	IPI	16129829
GO:0017048	Rho GTPase binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for ECT2

5/93 Interacting proteins for ECT2 (Q9H8V3^{1, 2} ENSP00000232458³) via UniProtKB, MINT, and/or STRING (see all 93 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RACGAP1	Q9H0H5², ENSP00000309871³	MINT-6166634 STRING (score=.996)
GRB2	P62993¹	EBI-1054039, EBI-401755
NCK1	P16333¹	EBI-1054039, EBI-389883
PIK3R1	P27986¹	EBI-1054039, EBI-79464
RACGAP1P	Q9H0H5²	MINT-6166634

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4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000902	cell morphogenesis	IEA	--
GO:0007242	intracellular signaling cascade	IEA	--
GO:0035023	regulation of Rho protein signal transduction	IEA	--
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	IMP	12761501

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Sigma-Aldrich Small Molecules for ECT2:

Inhibitor

Browse Tocris compounds for ECT2

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ECT2)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_018098

Sigma-Aldrich siRNA and siRNA Panels for ECT2

Sigma-Aldrich shRNA Panels and shRNA for ECT2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_018098

REFSEQ mRNAs for ECT2 gene:

NM_018098.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_018098

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_018098
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_018098
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_018098

Additional cDNA sequence:

AK001323.1 AK001515.1 AK023267.1 AK027713.1 AK308391.1 AK314581.1 AL137710.1 AY376439.1

BC006838.1 BC006987.1 BC070038.1 BC112086.1 DQ847274.1

17 DOTS entries:

DT.97792898 DT.91760878 DT.95197878 DT.120841247 DT.95197867 DT.120841246 DT.120841265 DT.95197895

DT.100790050 DT.120841248 DT.95197876 DT.97770594 DT.97789650 DT.95197881 DT.95197893 DT.99929308

DT.99990338

24/181 AceView cDNA sequences (see all 181 ):

AI823992 BQ925030 AW963051 AA301103 AU128730 AI038579 AI566535 CB128759

BM770300 BM995738 AW511311 BG613806 BC070038 BM840493 AI738508 AI370562

CD654947 BM787257 BQ229951 AU129613 BM827335 CD652117 BU619490 AK027713

highest scoring ESTs for ECT2:

AI823992 AA172248 AA279942 AA343765 AA506076 AA578848 AA766315 AA769228 AA973322 AA992180

Unigene Cluster for ECT2:

Epithelial cell transforming sequence 2 oncogene

Hs.518299 [show with all ESTs]

Unigene Representative Sequence: AY376439

GeneLoc Exon Structure

5/13 Alternative Splicing Database (ASD) splice patterns (SP) for ECT2 (see all 13 )

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4	^	5	^	6	^	7a	·	7b	^	8a	·	8b	^	9	^	10a	·	10b	^	11a	·	11b	^	12a	·	12b	^	13	^	14a	·	14b	^	15	^	16	^	17	^	18	^
SP1:															-
SP2:
SP3:							-		-						-
SP4:
SP5:							-		-

ExUns:	19	^	20	^	21	^	22a	·	22b	^	23a	·	23b	^	24a	·	24b	^	25a	·	25b	^	26	^	27a	·	27b	^	28a	·	28b
SP1:													-		-
SP2:													-		-										-		-
SP3:
SP4:													-		-										-
SP5:

About this scheme

ECgene alternative splicing isoforms for ECT2

2 Ensembl transcripts including schematic representations:

ENST00000392692 ENST00000232458

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ECT2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ECT2

¹ / ² / ³

6 probe-sets matching ECT2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
59461_at²^{, 3}	U95-C	1	1.00	1.00	1.00	1.00	AI823992	1.00	1.00	1.00	1
74829_at²^{, 3}	U95-E	1	0.94	1.00	0.32	0.31	AI738508	0.60	1.00	0.82	1
219787_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_018098	0.60	1.00	0.82	1
234992_x_at²^{, 3}	U133-B	1	0.73	1.00	--	--	BG170335	0.60	1.00	0.82	1
219787_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
234992_x_at²	U133Plus2	1	0.73	1.00	--	--	--	--	--	--	--

GeneDecks ECT2 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TATGTGCCAC

SOURCE GeneReport for Unigene cluster: Hs.518299

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ECT2 gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ECT2¹	--	epithelial cell transforming sequence 2 oncogene	92.83(n) 94.79(a)	488172 XM_845748.1 XP_850841.1
chimpanzee (Pan troglodytes)	ECT2¹	--	epithelial cell transforming sequence 2 oncogene	98.77(n) 98.73(a)	460853 XM_516880.2 XP_516880.2
cow (Bos taurus)	ECT2¹	--	epithelial cell transforming sequence 2 oncogene	91.69(n) 92.3(a)	504746 XM_580911.3 XP_580911.3
rat (Rattus norvegicus)	Ect2¹	--	epithelial cell transforming sequence 2 oncogene	86.39(n) 90.36(a)	361921 XM_342220.3 XP_342221.2
mouse (Mus musculus)	Ect2^{1, 5}	3⁵	ect2 oncogene^{1, 5}	87.71(n)¹ 94.17(a)¹	13605¹ NM_007900.2¹ NP_031926.1¹ AI528536⁵ AK040174⁵ (see all 12)

About this table Species with no ortholog for ECT2

ENSEMBL Gene Tree for ECT2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ECT2 gene

ARHGEF17²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/356 NCBI SNPs in ECT2 are shown (see all 356 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 101)

AB	SNP ID	Valid	Chr 3 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs4331694^1,2	A,C,F,H	174021044(+)	`ATGGGC/TGGGTG`	1	--	ut3¹ ese³		7	EU EA WA NA	552
	rs34703432^1,2	C,F	173955058(-)	`CCAAGC/GTAGTC`	1	S/T	mis¹		5	NA EU EA WA	498
	rs12638338^1,2	C,F	173950404(+)	`TAATAG/ACAACG`	1	--	ng5¹		2	MN EA	1252
--	rs13070560^1,2	F	173950393(+)	`AATTAC/TTTTCA`	1	--	ng5¹ tfbs³		2	MN EA	1252
--	rs5854482^1,2	F	173951166(+)	`GCCCCT/-CTGGA`	1	--	ng5¹		2	MN EA	1252
	rs34742755^1,2	F	173955811(-)	`AACCAA/GTATCA`	1	L/L	syn¹		1	NA	78
	rs2049230^1,2	A,C,F,H,O	173963716(+)	`AACTTA/TGACTT`	1	--	int¹		21	NA EA NS MN EU WA	1580
	rs10804849^1,2	A,C,F,H	173996988(+)	`tagcaA/Gtaatc`	1	--	int¹		3	EA WA	298
	rs7646507^1,2	A,C,F,H	173959113(+)	`TTAATA/GACATT`	1	--	int¹		4	EU EA WA	416
	rs4894433^1,2	A,C,F,H	173971770(+)	`ATCACT/CAGCAT`	1	--	int¹		4	EU EA WA	416

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HapMap Linkage Disequilibrium images for ECT2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 600586

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/40 PubMed articles for ECT2 gene (see all 40 ):

A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)^{3, 4} Beausoleil S.A.... Gygi S.P. (2006)
MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesis. (PubMed id 16129829)^{3, 4} Zhao W.-M. and Fang G. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Human ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesis. (PubMed id 10579713)^{2, 3} Tatsumoto T....Miki T. (1999)
Oncogene ect2 is related to regulators of small GTP-binding proteins. (PubMed id 8464478)^{2, 3} Miki T.... Fleming T.P. (1993)
The tandem BRCT domains of Ect2 are required for both negative and positive regulation of Ect2 in cytokinesis. (PubMed id 15545273)^{1, 3} Kim J.E....Chen J. (2005)
Rho exchange factor ECT2 is induced by growth factors and regulates cytokinesis through the N-terminal cell cycle regulator-related domains. (PubMed id 14587037)^{1, 3} Saito S....Miki T. (2003)
Phosphorylation of the cytokinesis regulator ECT2 at G2/M phase stimulates association of the mitotic kinase Plk1 and accumulation of GTP-bound RhoA. (PubMed id 16247472)^{1, 3} Niiya F....Miki T. (2006)
Inhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ECT2 and MgcRacGAP-dependent manner. (PubMed id 16118207)^{1, 3} Niiya F....Miki T. (2005)
CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase. (PubMed id 19015243)^{1, 3} Seguin L....Bertoglio J. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 1894	HGNC: 3155	AceView: ECT2	Ensembl:ENSG00000114346	euGenes: HUgn1894
ECgene: ECT2	H-InvDB: ECT2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for ECT2	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for ECT2
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for ECT2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ECT2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ECT2		Antibodies for ECT2
	Explore super-pooled esiRNAs		Proteins for ECT2
	Lentivirus-delivered shRNAs for ECT2		Small molecules for ECT2
	"Your Favorite Gene" Pathways		feedback

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	Recombinant & Natural Proteins

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ECT2 Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for ECT2

Summaries
for ECT2

Genomic Location
for ECT2

Proteins
for ECT2

Protein Domains/
Families
for ECT2

Gene Function
for ECT2

Pathways & Interactions
for ECT2

Drugs & Compounds
for ECT2

Transcripts
for ECT2

Expression
for ECT2

Orthologs
for ECT2

Paralogs
for ECT2

SNPs/Variants
for ECT2

Disorders & Mutations
for ECT2

Medical News
for ECT2

Publications
for ECT2

Search for ECT2

Genome Databases showing ECT2

Other Databases showing ECT2

Specialized Databases showing ECT2

Licensable Technologies
for ECT2

Services
for ECT2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ECT2 Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor ECT2

Summariesfor ECT2

Genomic Locationfor ECT2

Proteinsfor ECT2

Protein Domains/Familiesfor ECT2

Gene Functionfor ECT2

Pathways & Interactionsfor ECT2

Drugs & Compoundsfor ECT2

Transcriptsfor ECT2

Expression for ECT2

Orthologsfor ECT2

Paralogsfor ECT2

SNPs/Variantsfor ECT2

Disorders & Mutationsfor ECT2

Medical Newsfor ECT2

Publicationsfor ECT2

Search for ECT2

Genome Databases showing ECT2

Other Databases showing ECT2

Specialized Databases showing ECT2

Licensable Technologiesfor ECT2

Servicesfor ECT2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ECT2

Summaries
for ECT2

Genomic Location
for ECT2

Proteins
for ECT2

Protein Domains/
Families
for ECT2

Gene Function
for ECT2

Pathways & Interactions
for ECT2

Drugs & Compounds
for ECT2

Transcripts
for ECT2

Expression
for ECT2

Orthologs
for ECT2

Paralogs
for ECT2

SNPs/Variants
for ECT2

Disorders & Mutations
for ECT2

Medical News
for ECT2

Publications
for ECT2

Licensable Technologies
for ECT2

Services
for ECT2