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ECH1 Gene

protein-coding GIFtS: 57

GC19M043997

enoyl Coenzyme A hydratase 1, peroxisomal
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EC 5.3.3.- ^³
HPXEL ^¹, ²

Descriptions
delta3,5-delta2,4-dienoyl-CoA isomerase ^²
dienoyl-CoA isomerase ^²
enoyl Coenzyme A hydratase 1, peroxisomal ^²
peroxisomal enoyl-CoA hydratase 1 ^²
peroxisomal enoyl-coenzyme A hydratase-like protein ^²

External Ids
HGNC: 3149¹
Entrez Gene: 1891²
UniProtKB: Q13011³
Ensembl: ENSG00000104823⁷

Search outside databases for aliases for ECH1 gene

Previous GC identifers: GC19M039918 GC19M039697 GC19M043982

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ECH1:

This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high

sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a

conserved domain characteristic of these proteins. The encoded protein, which contains a

C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which

localizes to the matrix of both the peroxisome and mitochondria, can isomerize

3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a

delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty

acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

[provided by RefSeq]

UniProtKB/Swiss-Prot: ECH1_HUMAN, Q13011

Function: Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA (By similarity)

Gene Wiki entry for ECH1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ECH1 gene

Entrez Gene cytogenetic band: 19q13.1 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.1

ECH1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19M043997: (about GC identifiers)

Start:	43,997,902 bp from pter
End:	44,014,337 bp from pter
Size:	16,436 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000019.8 NT_011109.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: ECH1_HUMAN, Q13011 (See protein sequence)

Recommended Name: Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial precursor

Size: 328 amino acids; 35816 Da

Subunit: Homohexamer (By similarity)

Subcellular location: Mitochondrion (By similarity). Peroxisome (By similarity)

PDB structures from and Proteopedia :

2VRE (3D)

Secondary accessions: Q8WVX0 Q96EZ9

REFSEQ proteins: NP_001389.2

ENSEMBL proteins:

ENSP00000221418

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
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	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (ECH1)
	Human Recombinant Proteins from Abnova (ECH1)

OriGene Purified Recombinant Human Protein: ECH1

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	IEA	--
GO:0005777	peroxisome	TAS	7558027

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Antibodies for ECH1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ECH1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (ECH1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ECH1)
	Novus Biologicals Antibodies for ECH1

Assays for ECH1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q13011

ProtoNet protein and cluster: Q13011

UniProtKB/Swiss-Prot: ECH1_HUMAN, Q13011

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ECH1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ECH1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): BC011792

Applied Biosystems Silencer® siRNAs for ECH1

Sigma-Aldrich siRNA and siRNA Panels for ECH1

Sigma-Aldrich shRNA for ECH1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ECH1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001398
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001398
untagged cDNA clones in CMV expression vector (see all 2): BC011792

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001398

UniProtKB/Swiss-Prot: ECH1_HUMAN, Q13011

Function: Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA (By similarity)

Enzyme Number (IUBMB): EC 5.3.3.-

Genatlas biochemistry entry for ECH1:

peroxisomal matrix protein,enoyl-CoA hydratase-like

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004300	enoyl-CoA hydratase activity	TAS	7558027
GO:0005515	protein binding	IPI	15383276
GO:0016853	isomerase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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5/8 Sigma-Aldrich "Your Favorite Gene" Pathways for ECH1 (Your Favorite Gene powered by Ingenuity) (see all 8 )

Lysine Degradation
Fatty Acid Metabolism
Butanoate Metabolism
Propanoate Metabolism
Tryptophan Metabolism

GeneDecks ECH1 for the pathways selected above

About GeneDecksing

UniProtKB/Swiss-Prot: ECH1_HUMAN, Q13011

Pathway: Lipid metabolism; fatty acid beta-oxidation

5/6 Interacting proteins for ECH1 (Q13011^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 6 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HTT	P42858¹^,²	EBI-711968, EBI-466029 MINT-3981370 MINT-3978118 EBI-711968, EBI-466029 MINT-3981370 MINT-3978118
HTT	P42858¹^,²	EBI-711968, EBI-466029 MINT-3981370 MINT-3978118 EBI-711968, EBI-466029 MINT-3981370 MINT-3978118
EEF1G	P26641²	MINT-3980625 MINT-63613
CSTF2	P33240²	MINT-63678
PAFAH1B3	Q15102²	MINT-64215

About this table
5 Gene Ontology (GO) biological process terms (links to tree view):
GO ID Qualified GO term Evidence PubMed IDs
GO:0006091 generation of precursor metabolites and energy TAS 7558027
GO:0006629 lipid metabolic process IEA --
GO:0006631 fatty acid metabolic process IEA --
GO:0006635 fatty acid beta-oxidation TAS 7558027
GO:0008152 metabolic process IEA --
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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ECH1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ECH1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ECH1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): BC011792

Sigma-Aldrich siRNA and siRNA Panels for ECH1

Sigma-Aldrich shRNA for ECH1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001398

REFSEQ mRNAs for ECH1 gene:

NM_001398.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001398

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001398
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001398
                                 untagged cDNA clones in CMV expression vector (see all 2): BC011792

Additional cDNA sequence:

AK126566.1 AK291860.1 AK301211.1 AY927476.1 BC011792.2 BC014786.1 BC017408.1 CR591368.1

CR593921.1 CR598218.1 CR600133.1 CR600240.1 CR603672.1 CR610523.1 CR611035.1 CR615338.1

CR620208.1 CR620644.1 CR622906.1 CR625294.1 U16660.1

24/30 DOTS entries (see all 30 ):

DT.75174730 DT.100045126 DT.95097900 DT.100873390 DT.100873375 DT.100873391 DT.121453531 DT.91764374

DT.100873373 DT.95171557 DT.92055209 DT.121453634 DT.101985500 DT.95171554 DT.121453566 DT.95171567

DT.95171569 DT.95299255 DT.100873381 DT.92441002 DT.100802315 DT.100835287 DT.100873382 DT.102833787

24/889 AceView cDNA sequences (see all 889 ):

AI344583 BX401432 BM974528 BM310387 CB159190 BC011792 BQ675225 CD611407

BU608053 BP870554 BI255093 BE904377 BE613773 AL559615 BQ276342 BQ878641

BX417514 CA406987 CR620208 F18477 BU195742 BV177689 BQ437897 CB147811

highest scoring ESTs for ECH1:

AA121210 AA149782 AA149795 AA211653 AA218655 AA306086 AA307959 AA313933 AA315329 AA326065

Unigene Cluster for ECH1:

Enoyl Coenzyme A hydratase 1, peroxisomal

Hs.196176 [show with all ESTs]

Unigene Representative Sequence: AK126566

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for ECH1 (see all 12 )

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	·	1f	^	2a	·	2b	·	2c	·	2d	^	3	^	4a	·	4b	^	5a	·	5b	^	6a	·	6b	^	7	^	8a	·	8b	^	9	^	10a	·	10b	·	10c
SP1:											-		-										-						-				-						-
SP2:											-		-										-						-				-
SP3:											-		-				-		-		-		-		-				-				-						-
SP4:													-										-						-				-
SP5:																													-				-						-

About this scheme

ECgene alternative splicing isoforms for ECH1

1 Ensembl transcript including schematic representation:

ENST00000221418

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ECH1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ECH1

¹ / ² / ³

4 probe-sets matching ECH1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
32756_at²^{, 3}	U95-A	1	1.00	1.00	0.98	0.91	AF030249	0.20	1.00	0.72	1
73116_s_at²^{, 3}	U95-E	1	1.00	1.00	0.99	1.09	AI434583	0.80	0.88	0.84	1
200789_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001398	0.60	0.83	0.73	1
200789_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CTGCAGACCC

SOURCE GeneReport for Unigene cluster: Hs.196176
Expression variation in blood from EXPOLDB for ECH1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ECH1 gene from 5/16 species (see all 16 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ECH1¹	--	enoyl Coenzyme A hydratase 1, peroxisomal	84.15(n) 79.88(a)	476467 XM_533678.2 XP_533678.1
chimpanzee (Pan troglodytes)	ECH1¹	--	enoyl Coenzyme A hydratase 1, peroxisomal	98.68(n) 98.17(a)	747511 XM_001167817.1 XP_001167817.1
cow (Bos taurus)	ECH1¹	--	enoyl Coenzyme A hydratase 1, peroxisomal	82.41(n) 77.91(a)	507431 XM_866888.2 XP_871981.1
rat (Rattus norvegicus)	Ech1¹	--	enoyl coenzyme A hydratase 1, peroxisomal	79.71(n) 75.23(a)	64526 NM_022594.1 NP_072116.1
mouse (Mus musculus)	Ech1^{1, 5}	7⁵	enoyl coenzyme A hydratase 1, peroxisomal^{1, 5}	79.92(n)¹ 74.31(a)¹	51798¹ NM_016772.1¹ NP_058052.1¹ AA617331⁵ AF030343⁵ (see all 10)

About this table Species with no ortholog for ECH1

ENSEMBL Gene Tree for ECH1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ECH1 gene

ECHDC3²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/105 NCBI SNPs in ECH1 are shown (see all 105 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 41)

AB	SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs9419^1,2	C,F,H	44013927(-)	`AGAGGA/CGGCTT`	1	E/A	mis¹		14		MN NA EU EA WA	1400
	rs2229259^1,2	C,F,H	43998943(-)	`TCATCG/AGGAAC`	1	R/G	mis¹		9		MN EA WA EU	2272
	rs7351057^1,2	C,F,H	44014877(+)	`CTATAT/CGCAGA`	1	--	ng3¹		8		EU EA WA	838
--	rs11549278^1,2	H	44013828(-)	`CAACCG/TGCCCA`	1	R/L	mis¹ ese³		4		EU EA WA	406
	rs1138526^1,2	C	43997926(-)	`ACCCCA/CCAAAC`	1	--	ut3¹		0	--	--	--	--
--	rs10411480^1,2	C	44015994(+)	`ggtggC/Ttcagg`	1	--	ng3¹		0	--	--	--	--
--	rs10411844^1,2	C	44015998(+)	`gctcaC/Ggtctg`	1	--	ng3¹		0	--	--	--	--
--	rs10413482^1,2	A	44016170(+)	`gcgggC/Tggatc`	1	--	ng3¹		0	--	--	--	--
--	rs17850798^1,2	C,F,H	44000030(+)	`ATGTCC/TGAAGC`	1	S/S	syn¹ ese³		8		EU EA NA WA	778
--	rs8104420^1,2	A,C,F,H	44006859(+)	`gttgcG/Agtttc`	1	--	int¹		4		EU EA WA	404

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HapMap Linkage Disequilibrium images for ECH1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 600696

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/12 PubMed articles for ECH1 gene (see all 12 ):

Isolation and characterization of rat and human cDNAs encoding a novel putative peroxisomal enoyl-CoA hydratase. (PubMed id 7558027)^{1, 2, 3, 4} Fitzpatrick D.R.... Valle D. (1995)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Polymorphism of delta3,5-delta2,4-dienoyl-coenzyme A isomerase (the ECH1 gene product protein) in human striated muscle tissue. (PubMed id 16615866)³ Kovalyov L.I....Shishkin S.S. (2006)
A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)³ Stelzl U....Wanker E.E. (2005)
A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease. (PubMed id 15383276)³ Goehler H....Wanker E.E. (2004)
Overexpression of peroxisome proliferator-activated receptor-alpha (PPARalpha)-regulated genes in liver in the absence of peroxisome proliferation in mice deficient in both L- and D-forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal beta-oxidation system. (PubMed id 14500732)³ Jia Y....Reddy J.K. (2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)
Delta3,5-delta2,4-dienoyl-CoA isomerase from rat liver. Molecular characterization. (PubMed id 9417087)³ Filppula S.A....Hiltunen J.K. (1998)
[Preparation and identification of monoclonal antibody against enoyl-CoA hydratase 1.] (PubMed id 19403386)¹ Ju Y.F....Sun Q.H. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 1891	HGNC: 3149	AceView: ECH1	Ensembl:ENSG00000104823	euGenes: HUgn1891
ECgene: ECH1	H-InvDB: ECH1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for ECH1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for ECH1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ECH1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ECH1		Antibodies for ECH1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ECH1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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	shRNA in GFP-retroviral vector

Search Tocris compounds for ECH1

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ECH1 Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for ECH1

Summaries
for ECH1

Genomic Location
for ECH1

Proteins
for ECH1

Protein Domains/
Families
for ECH1

Gene Function
for ECH1

Pathways & Interactions
for ECH1

Drugs & Compounds
for ECH1

Transcripts
for ECH1

Expression
for ECH1

Orthologs
for ECH1

Paralogs
for ECH1

SNPs/Variants
for ECH1

Disorders & Mutations
for ECH1

Medical News
for ECH1

Publications
for ECH1

Search for ECH1

Genome Databases showing ECH1

Other Databases showing ECH1

Specialized Databases showing ECH1

Licensable Technologies
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Services
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ECH1 Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor ECH1

Summariesfor ECH1

Genomic Locationfor ECH1

Proteinsfor ECH1

Protein Domains/Familiesfor ECH1

Gene Functionfor ECH1

Pathways & Interactionsfor ECH1

Drugs & Compoundsfor ECH1

Transcriptsfor ECH1

Expression for ECH1

Orthologsfor ECH1

Paralogsfor ECH1

SNPs/Variantsfor ECH1

Disorders & Mutationsfor ECH1

Medical Newsfor ECH1

Publicationsfor ECH1

Search for ECH1

Genome Databases showing ECH1

Other Databases showing ECH1

Specialized Databases showing ECH1

Licensable Technologiesfor ECH1

Servicesfor ECH1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ECH1

Summaries
for ECH1

Genomic Location
for ECH1

Proteins
for ECH1

Protein Domains/
Families
for ECH1

Gene Function
for ECH1

Pathways & Interactions
for ECH1

Drugs & Compounds
for ECH1

Transcripts
for ECH1

Expression
for ECH1

Orthologs
for ECH1

Paralogs
for ECH1

SNPs/Variants
for ECH1

Disorders & Mutations
for ECH1

Medical News
for ECH1

Publications
for ECH1

Licensable Technologies
for ECH1

Services
for ECH1