Aliases for EBF3 Gene
External Ids for EBF3 Gene
Previous GeneCards Identifiers for EBF3 Gene
This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma. [provided by RefSeq, Sep 2011]
GeneCards Summary for EBF3 Gene
EBF3 (Early B-Cell Factor 3) is a Protein Coding gene. GO annotations related to this gene include protein dimerization activity. An important paralog of this gene is EBF2.
UniProtKB/Swiss-Prot for EBF3 Gene
Transcriptional activator which recognizes variations of the palindromic sequence 5-ATTCCCNNGGGAATT-3.