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EBF2 Gene

protein-coding   GIFtS: 48
GCID: GC08M025757

Early B-Cell Factor 2

  Search for EBF2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Early B-Cell Factor 21 2 3     Collier, Olf And EBF 22
COE22 3     Metencephalon-Mesencephalnon-Olfactory Transcription Factor 12
EBF-22 3     OLF-1/EBF-LIKE 32
O/E-32     Transcription Factor COE22
OE-32     

External Ids:    HGNC: 190901   Entrez Gene: 646412   Ensembl: ENSG000002218187   OMIM: 6099345   UniProtKB: Q9HAK23   

Export aliases for EBF2 gene to outside databases

Previous GC identifers: GC08M025474 GC08M026054 GC08M025723 GC08M024246


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for EBF2 Gene:
The protein encoded by this gene belongs to the COE (Collier/Olf/EBF) family of non-basic, helix-loop-helix
transcription factors that have a well conserved DNA binding domain. The COE family proteins play an important
role in variety of developmental processes. Studies in mouse suggest that this gene may be involved in the
differentiation of osteoblasts. (provided by RefSeq, Oct 2011)

GeneCards Summary for EBF2 Gene:
EBF2 (early B-cell factor 2) is a protein-coding gene. GO annotations related to this gene include protein dimerization activity. An important paralog of this gene is EBF3.

UniProtKB/Swiss-Prot: COE2_HUMAN, Q9HAK2
Function: Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in
turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway.
Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NC_018919.2  NT_167187.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the EBF2 gene promoter:
         NF-YA   FOXO3   NF-YB   CBF-A   CBF-B   FOXO3a   CP1A   MRF-2   NF-Y   CBF(2)   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for EBF2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat EBF2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p21.2   Ensembl cytogenetic band:  8p21.2   HGNC cytogenetic band: 8p21.1

EBF2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
EBF2 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M025757:  view genomic region     (about GC identifiers)

Start:
25,699,246 bp from pter      End:
25,902,913 bp from pter
Size:
203,668 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: COE2_HUMAN, Q9HAK2 (See protein sequence)
Recommended Name: Transcription factor COE2  
Size: 575 amino acids; 62650 Da
Subunit: Forms either a homodimer or a heterodimer with a related family member (By similarity)
Sequence caution: Sequence=BAB13843.1; Type=Erroneous initiation;
Secondary accessions: A0PJM4 A6NMF7 Q6DK36 Q6IS86 Q6ISA4

Explore the universe of human proteins at neXtProt for EBF2: NX_Q9HAK2

Explore proteomics data for EBF2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See EBF2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_073150.2  
    ENSEMBL proteins: 
     ENSP00000430241   ENSP00000386178   ENSP00000437909  

    EBF2 Human Recombinant Protein Products:

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    LSBio Antibodies in human, mouse, rat for EBF2

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    Search eBioscience for ELISAs for EBF2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 6):
     IPR014756 Ig_E-set
     IPR011598 bHLH_dom
     IPR002909 IPT
     IPR018350 Transcription_factor_COE_CS
     IPR013783 Ig-like_fold

    Graphical View of Domain Structure for InterPro Entry Q9HAK2

    ProtoNet protein and cluster: Q9HAK2

    3 Blocks protein domains:
    IPB001092 Basic helix-loop-helix dimerization domain bHLH
    IPB002909 Cell surface receptor IPT/TIG
    IPB003523 Transcription factor COE


    UniProtKB/Swiss-Prot: COE2_HUMAN, Q9HAK2
    Similarity: Belongs to the COE family
    Similarity: Contains 1 IPT/TIG domain


    Find genes that share domains with EBF2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COE2_HUMAN, Q9HAK2
    Function: Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in
    turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway.
    Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0005515protein binding ----
    GO:0046872metal ion binding IEA--
    GO:0046983protein dimerization activity IEA--
         
    Find genes that share ontologies with EBF2           About GenesLikeMe


    Phenotypes:
         14 MGI mutant phenotypes (inferred from 8 alleles(MGI details for Ebf2):
     adipose tissue  behavior/neurological  cellular  craniofacial  endocrine/exocrine gland 
     growth/size/body  limbs/digits/tail  mortality/aging  nervous system  normal 
     reproductive system  respiratory system  skeleton  taste/olfaction 

    Find genes that share phenotypes with EBF2           About GenesLikeMe

    Animal Models:
         MGI mouse knock-outs for EBF2: Ebf2tm1Ddr Ebf2tm1Ggc

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for EBF2
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    Selected qRT-PCR Assays for microRNAs that regulate EBF2 (see all 24):
    hsa-miR-3685 hsa-miR-3200-5p hsa-miR-520f hsa-miR-1263 hsa-miR-376b hsa-miR-520d-5p hsa-miR-10b hsa-miR-488
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EBF2

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    COE2_HUMAN, Q9HAK2: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with EBF2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for EBF2
    Interactions:

        Search GeneGlobe Interaction Network for EBF2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for EBF2 (Q9HAK23 ENSP000003861784) via UniProtKB, MINT, STRING, and/or I2D (see all 61)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ZNF423Q2M1K93, ENSP000002623834I2D: score=1 STRING: ENSP00000262383
    EBF4Q9BQW33I2D: score=1 
    ANKZF1ENSP000003216174STRING: ENSP00000321617
    NPLOC4ENSP000003314874STRING: ENSP00000331487
    ZMPSTE24ENSP000003618454STRING: ENSP00000361845
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0007275multicellular organismal development IEA--
    GO:0045893positive regulation of transcription, DNA-templated IEA--

    Find genes that share ontologies with EBF2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for EBF2 (COE2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for EBF2 gene: 
    NM_022659.3  

    Unigene Cluster for EBF2:

    Early B-cell factor 2
    Hs.491292  [show with all ESTs]
    Unigene Representative Sequence: NM_022659
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000520164(uc010lug.2 uc003xes.2) ENST00000408929 ENST00000517825(uc003xet.2)
    ENST00000535548
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate EBF2 (see all 24):
    hsa-miR-3685 hsa-miR-3200-5p hsa-miR-520f hsa-miR-1263 hsa-miR-376b hsa-miR-520d-5p hsa-miR-10b hsa-miR-488
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat EBF2
      QuantiFast Probe-based Assays in human, mouse, rat EBF2

    Additional mRNA sequence: 

    AK001144.1 AK021562.1 AK093878.1 AK304372.1 BC069665.1 BC069726.1 BC069747.1 BC069768.1 
    BC074794.2 BC113478.1 BC113504.1 BC137106.1 BC137107.1 

    3 DOTS entries:

    DT.75105086  DT.99941220  DT.70102522 

    Selected AceView cDNA sequences (see all 30):

    BQ878633 AK021562 BC069726 AI457889 BC074794 BC069768 NM_022659 BX282733 
    AU117744 AY700779 AA911958 AL706446 BQ889735 AA311763 AI200996 BC069747 
    AI016316 BC069665 BI488508 AK093878 W92336 AW962848 AI744592 AU144494 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    EBF2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTTTAAAAAC
    EBF2 Expression
    About this image


    EBF2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 9 entries
             Thalamus
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Telencephalon
     
     Neurons
             Cone Bipolar Precursor Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)    fully expand to see all 2 entries
             Cone Bipolar Precursor Cells Inner Nuclear Layer
     
     Spinal Cord (Nervous System)
    EBF2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    EBF2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.491292
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for EBF2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ebf21 , 5 early B cell factor 21, 5 89.91(n)1
    99.48(a)1
      14 (34.63 cM)5
    135921  NM_010095.61  NP_034225.11 
     672332925 
    chicken
    (Gallus gallus)
    Aves EBF21 early B-cell factor 2 84.06(n)
    98.43(a)
      395176  NM_001164536.1  NP_001158008.1 
    lizard
    (Anolis carolinensis)
    Reptilia EBF26
    early B-cell factor 2
    92(a)
    1 ↔ 1
    GL344110.1(1207-46748)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia ebf21 early B-cell factor 2 78.22(n)
    93.9(a)
      394808  NM_203869.1  NP_989200.1 
    zebrafish
    (Danio rerio)
    Actinopterygii coe21 coe2 70.77(n)
    81.87(a)
      30692  NM_131418.1  NP_571493.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta kn6
    knot
    50(a)
    1 → many
    2R(10660152-10694566)
    worm
    (Caenorhabditis elegans)
    Secernentea unc-36
    Protein UNC-3 (unc-3) mRNA, complete cds
    54(a)
    1 → many
    X(14773538-14783564) WBGene00006743


    ENSEMBL Gene Tree for EBF2 (if available)
    TreeFam Gene Tree for EBF2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for EBF2 gene
    EBF32  EBF42  EBF12  
    4 SIMAP similar genes for EBF2 using alignment to 5 protein entries:     COE2_HUMAN (see all proteins):
    DKFZp667I0324    EBF3    EBF1    EBF4

    Find genes that share paralogs with EBF2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for EBF2 (see all 4490)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs561706181,2
    C--24302084(+) TCCAA-/CC    
       ACCCT
    GTGGA
    1 -- int10--------
    rs58902671,2
    C--24314744(+) AGGAG-/A/AA  
            
    AAAAA
    1 -- int11NA 2
    rs2001266801,2
    C--24323307(+) AAAAAA/GGGAAA 1 -- int10--------
    rs2014187501,2
    C--24323309(-) TTTTTC/TCTTTT 1 -- int10--------
    rs107125031,2
    C--24334616(+) AAAAA-/A/AA  
            
    GAACG
    1 -- int12NA 4
    rs58902691,2
    C--24343427(+) TTTTTT/-CGAGA 1 -- int11Minor allele frequency- -:0.50CSA 2
    rs1421728091,2
    C--24350979(+) CTCAC-/AGGAACT 1 -- int10--------
    rs2002338421,2
    C--24378864(+) AAAAC-/AAAAAC 1 -- int10--------
    rs58902731,2
    C--24380506(+) GTGGC-/CGCGCCA 1 -- int10--------
    rs357398631,2
    C--24383126(+) CCCCC-/TTCACC 1 -- int11Minor allele frequency- T:0.00NA 2

    HapMap Linkage Disequilibrium report for EBF2 (25699246 - 25902913 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for EBF2 (see all 15):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2736785CNV Deletion23290073
    esv2672485CNV Deletion23128226
    esv2736786CNV Deletion23290073
    esv1052787CNV Insertion17803354
    nsv6127CNV Insertion18451855
    esv2500463CNV Insertion19546169
    esv1423053CNV Insertion17803354
    esv1420594CNV Insertion17803354
    esv1009767CNV Insertion20482838
    esv267421CNV Insertion20981092

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609934    OMIM disorders: --


    Find genes that share disorders with EBF2           About GenesLikeMe

    Genetic Association Database (GAD): EBF2
    Human Genome Epidemiology (HuGE) Navigator: EBF2 (5 documents)

    Export disorders for EBF2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for EBF2 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with EBF2)
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    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)1, 4 He C....Hunter D.J. (Hum. Genet. 2010)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)1, 2 Nusbaum C....Lander E.S. (Nature 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. The characterization of the Olf-1/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development. (PubMed id 9151732)1, 3 Wang S.S....Reed R.R. (J. Neurosci. 1997)
    8. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (Nat. Genet. 2013)
    9. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    10. Profiling of chemonaive osteosarcoma and paired-normal cells identifies EBF2 as a mediator of osteoprotegerin inhibition to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. (PubMed id 19671856)1 PatiA+o-GarcA-a A....Lecanda F. (Clin. Cancer Res. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64641 HGNC: 19090 AceView: EBF2 Ensembl:ENSG00000221818 euGenes: HUgn64641
    ECgene: EBF2 H-InvDB: EBF2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for EBF2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for EBF2 gene:
    Search GeneIP for patents involving EBF2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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