Aliases for EBAG9 Gene
External Ids for EBAG9 Gene
Previous GeneCards Identifiers for EBAG9 Gene
This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10. [provided by RefSeq, Jul 2013]
GeneCards Summary for EBAG9 Gene
EBAG9 (Estrogen Receptor Binding Site Associated, Antigen, 9) is a Protein Coding gene. Diseases associated with EBAG9 include placental abruption and bile duct carcinoma. GO annotations related to this gene include peptidase activator activity involved in apoptotic process.
UniProtKB/Swiss-Prot for EBAG9 Gene
May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.