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EAPP Gene

protein-coding GIFtS: 46

GC14M034055

E2F-associated phosphoprotein
(Previous name: chromosome 14 open reading frame 11 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: C14orf11)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
BM036 ^¹, ²
C14orf11 ^², ³
FLJ20578 ^¹, ²
MGC4957 ^²

Descriptions
E2F-associated phosphoprotein ^²
chromosome 14 open reading frame 11 ^¹

External Ids
HGNC: 19312¹
Entrez Gene: 55837²
UniProtKB: Q56P03³
Ensembl: ENSG00000129518⁷

Search outside databases for aliases for EAPP gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for EAPP:

This gene encodes a phosphoprotein that interacts with several members of the E2F family of

proteins. The protein localizes to the nucleus, and is present throughout the cell cycle except

during mitosis. It functions to modulate E2F-regulated transcription and stimulate proliferation.

[provided by RefSeq]

UniProtKB/Swiss-Prot: EAPP_HUMAN, Q56P03

Function: May play an important role in the fine-tuning of both major E2F1 activities, the

regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits

p14(ARP) expression

Gene Wiki entry for EAPP

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q13.1 Ensembl cytogenetic band: 14q13.1 HGNC cytogenetic band: 14q13

EAPP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14M034055: (about GC identifiers)

Start:	34,054,886 bp from pter
End:	34,078,694 bp from pter
Size:	23,809 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000014.7 NT_026437.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: EAPP_HUMAN, Q56P03 (See protein sequence)

Recommended Name: E2F-associated phosphoprotein

Size: 285 amino acids; 32734 Da

Subunit: Interacts with E2F1. The C-terminal half binds the N-terminal of E2F1. Also interacts with

E2F2 and E2F3, but not E2F4

Subcellular location: Cytoplasm. Nucleus

Developmental stage: During the cell cycle, expression disappears during mitosis

Sequence caution: Sequence=AAF67623.1; Type=Frameshift; Positions=178, 189, 198, 226;

Sequence=AAO17041.1; Type=Frameshift; Positions=178, 189, 198, 226; Sequence=AAO17042.1;

Type=Frameshift; Positions=178, 189, 198, 226;

Secondary accessions: Q9BVF4 Q9NWV5 Q9NZ86

Post-translational modifications:

Phosphorylated¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_060923.2

ENSEMBL proteins:

ENSP00000250454

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse Abcam for Recombinant Proteins
	Browse Abnova for Human Recombinant Proteins

OriGene Purified Recombinant Human Protein: EAPP

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005737	cytoplasm	IEA	--
GO:0005794	Golgi apparatus	IDA	18029348

About this table

Antibodies for EAPP:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for EAPP
	Browse R&D Systems for Antibodies
	Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for EAPP

Assays for EAPP:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q56P03

ProtoNet protein and cluster: Q56P03

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EAPP)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_018453

Applied Biosystems Silencer® siRNAs for EAPP

Sigma-Aldrich siRNA for EAPP

Sigma-Aldrich shRNA for EAPP

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_018453
Myc/DDK tagged cDNA clone in CMV expression vector: NM_018453
untagged cDNA clones in CMV expression vector (see all 2): NM_018453

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_018453

UniProtKB/Swiss-Prot: EAPP_HUMAN, Q56P03

Function: May play an important role in the fine-tuning of both major E2F1 activities, the

regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits

p14(ARP) expression

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/7 Interacting proteins for EAPP (ENSP00000250454³ Q56P03²) via UniProtKB, MINT, and/or STRING (see all 7 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UBE3A	Q05086²	MINT-2874650
UBQLN4	Q9NRR5²	MINT-2874631
E2F2	ENSP00000355249³	STRING (score=.928)
E2F1	ENSP00000345571³	STRING (score=.892)
EGR1	ENSP00000239938³	STRING (score=.872)

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for EAPP

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EAPP)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_018453

Sigma-Aldrich siRNA for EAPP

Sigma-Aldrich shRNA for EAPP

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_018453

REFSEQ mRNAs for EAPP gene:

NM_018453.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_018453

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_018453
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_018453
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_018453

Additional cDNA sequence:

AF217512.1 AK000585.1 AK225467.1 AK225477.1 AK225991.1 AY157300.1 AY157301.1 AY869694.1

BC001245.1 CR609381.1

10 DOTS entries:

DT.448951 DT.99998772 DT.95086769 DT.100680953 DT.120790963 DT.97765627 DT.97800149 DT.100821684

DT.120790976 DT.92428950

24/242 AceView cDNA sequences (see all 242 ):

AV718179 BQ651747 BG680985 AA046315 BQ651756 CA455313 BU661711 CB988297

AA286852 BP348176 AI869090 AW015457 BI912427 BM719002 D79463 AA676250

BM479939 AI356848 AA582111 AI365641 BU856994 CB157729 BM682986 BQ644142

Unigene Cluster for EAPP:

E2F-associated phosphoprotein

Hs.433269 [show with all ESTs]

Unigene Representative Sequence: NM_018453

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for EAPP (see all 6 )

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	^	2a	·	2b	·	2c	^	3	^	4a	·	4b	^	5	^	6a	·	6b
SP1:									-		-				-
SP2:									-		-				-				-		-
SP3:									-		-				-
SP4:											-				-
SP5:															-

About this scheme

ECgene alternative splicing isoforms for EAPP

1 Ensembl transcript including schematic representation:

ENST00000250454

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

EAPP expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for EAPP

¹ / ²

5 probe-sets matching EAPP gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
37315_f_at²	U95-A	1	1.00	1.00	0.90	0.91	--	--	--	--	--
75194_at²	U95-D	1	1.00	1.00	0.85	1.37	--	--	--	--	--
37316_r_at²	U95-A	1	1.00	1.00	-0.12	0.72	--	--	--	--	--
202623_at²	U133-A	1	1.00	1.00	--	--	--	--	--	--	--
202623_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGCACTGAAT

SOURCE GeneReport for Unigene cluster: Hs.433269
UniProtKB/Swiss-Prot: EAPP_HUMAN, Q56P03
Tissue specificity: Ubiquitously expressed. Highest levels in heart, placenta, skeletal muscle and
pancreas. Lower levels in brain, lung and kidney. In the brain, expressed in all regions with high
levels in the cerebellum and cerebral cortex. Expressed in COS1 and transformed skin fibroblasts

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for EAPP gene from 5/12 species (see all 12 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	EAPP¹	--	E2F-associated phosphoprotein	87.95(n) 87.72(a)	490647 XM_856416.1 XP_861509.1
chimpanzee (Pan troglodytes)	EAPP¹	--	E2F-associated phosphoprotein	99.53(n) 99.3(a)	452852 XM_509897.2 XP_509897.2
cow (Bos taurus)	EAPP¹	--	E2F-associated phosphoprotein	90.85(n) 92.25(a)	520143 NM_001075800.1 NP_001069268.1
rat (Rattus norvegicus)	Eapp¹	--	E2F-associated phosphoprotein	84.95(n) 89.61(a)	299043 XM_216706.4 XP_216706.1
mouse (Mus musculus)	Eapp^{1, 5}	12⁵	E2F-associated phosphoprotein^{1, 5}	84.4(n)¹ 88.57(a)¹	66266¹ NM_025456.3¹ NP_079732.1¹ AI527248⁵ AK007442⁵ (see all 12)

About this table Species with no ortholog for EAPP

ENSEMBL Gene Tree for EAPP

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/170 NCBI SNPs in EAPP are shown (see all 170 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 27)

AB	SNP ID	Valid	Chr 14 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs7766^1,2	A,C,F,H,O	34055257(-)	`CCCAAC/GTGGCA`	1	--	ut3¹ ese³		9		MN NA EA WA	792
--	rs11845381^1,2	A,C,F,H	34054664(+)	`tttctA/Gttttt`	1	--	ng5¹		4		EU EA WA	418
--	rs17856038^1,2	C,F,H	34063733(+)	`TTGTTG/CACGTG`	1	E/Q	mis¹ ese³		8		EU EA WA	838
	rs4368076^1,2	C,F,H	34079384(+)	`CAACCG/TCTCCT`	1	--	ng3¹ trp³		15		NA MN EA EU WA	2406
--	rs7147947^1,2	A,C	34078822(+)	`tttttG/Tttttg`	1	--	ng3¹		0	--	--	--	--
	rs17102603^1,2	F,H	34079629(+)	`AAAATG/ATGGAG`	1	--	ng3¹		7		NA EU EA WA	556
	rs7797^1,2	A,C,F,H	34055396(-)	`GCTGCC/TGAGAA`	1	A/A	syn¹		10		MN EU EA WA	1212
	rs7144711^1,2	A,C,F,H	34074855(+)	`AATCTA/GAAGTA`	1	--	int¹		4		EU EA WA	392
	rs12883317^1,2	A,C,F,H	34066258(+)	`ctctaC/Ttaaaa`	1	--	int¹		6		EU WA EA	638
	rs8019556^1,2	A,C,F,H	34061376(+)	`taaggA/Gttcac`	1	--	int¹		12		EU EA WA NA	1040

About this table

HapMap Linkage Disequilibrium images for EAPP (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 609486

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/14 PubMed articles for EAPP gene (see all 14 ):

EAPP, a novel E2F binding protein that modulates E2F-dependent transcription. (PubMed id 15716352)^{1, 2, 3, 4} Novy M.... Rotheneder H. (2005)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
Defining a holoprosencephaly locus on human chromosome 14q13 and characterization of potential candidate genes. (PubMed id 15820313)^{3, 4} Kamnasaran D.... Cox D.W. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{3, 4} Zhang Q.H....Chen Z. (2000)
Regulation of the E2F-associated phosphoprotein promoter by GC-box binding proteins. (PubMed id 18588995)^{1, 3} Schwarzmayr L....Rotheneder H. (2008)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)⁴ Dephoure N.... Gygi S.P. (2008)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)³ Barbe L....Andersson-Svahn H. (2008)
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)³ Lim J....Zoghbi H.Y. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 55837	HGNC: 19312	AceView: C14orf11	Ensembl:ENSG00000129518	euGenes: HUgn55837
ECgene: EAPP	H-InvDB: EAPP

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for EAPP
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for EAPP:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for EAPP-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for EAPP		Antibodies for EAPP
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for EAPP		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Cell Culture Products		ELISAs
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	Recombinant & Natural Proteins

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EAPP Gene

protein-coding GIFtS: 46

Aliases &
Descriptions
for EAPP

Summaries
for EAPP

Genomic Location
for EAPP

Proteins
for EAPP

Protein Domains/
Families
for EAPP

Gene Function
for EAPP

Pathways & Interactions
for EAPP

Drugs & Compounds
for EAPP

Transcripts
for EAPP

Expression
for EAPP

Orthologs
for EAPP

Paralogs
for EAPP

SNPs/Variants
for EAPP

Disorders & Mutations
for EAPP

Medical News
for EAPP

Publications
for EAPP

Search for EAPP

Genome Databases showing EAPP

Other Databases showing EAPP

Specialized Databases showing EAPP

Licensable Technologies
for EAPP

Services
for EAPP

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

EAPP Gene

protein-coding GIFtS: 46

Aliases & Descriptionsfor EAPP

Summariesfor EAPP

Genomic Locationfor EAPP

Proteinsfor EAPP

Protein Domains/Familiesfor EAPP

Gene Functionfor EAPP

Pathways & Interactionsfor EAPP

Drugs & Compoundsfor EAPP

Transcriptsfor EAPP

Expression for EAPP

Orthologsfor EAPP

Paralogsfor EAPP

SNPs/Variantsfor EAPP

Disorders & Mutationsfor EAPP

Medical Newsfor EAPP

Publicationsfor EAPP

Search for EAPP

Genome Databases showing EAPP

Other Databases showing EAPP

Specialized Databases showing EAPP

Licensable Technologiesfor EAPP

Servicesfor EAPP

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for EAPP

Summaries
for EAPP

Genomic Location
for EAPP

Proteins
for EAPP

Protein Domains/
Families
for EAPP

Gene Function
for EAPP

Pathways & Interactions
for EAPP

Drugs & Compounds
for EAPP

Transcripts
for EAPP

Expression
for EAPP

Orthologs
for EAPP

Paralogs
for EAPP

SNPs/Variants
for EAPP

Disorders & Mutations
for EAPP

Medical News
for EAPP

Publications
for EAPP

Licensable Technologies
for EAPP

Services
for EAPP