Aliases for EAF2 Gene
External Ids for EAF2 Gene
Previous GeneCards Identifiers for EAF2 Gene
GeneCards Summary for EAF2 Gene
EAF2 (ELL Associated Factor 2) is a Protein Coding gene. Diseases associated with EAF2 include Eaf and Childhood Leukemia. Among its related pathways are Gene Expression and Formation of HIV elongation complex in the absence of HIV Tat. GO annotations related to this gene include RNA polymerase II regulatory region sequence-specific DNA binding and transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding. An important paralog of this gene is EAF1.
UniProtKB/Swiss-Prot for EAF2 Gene
Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo.