V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

E2F5 Gene

protein-coding GIFtS: 60

GC08P086276

E2F transcription factor 5, p130-binding
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
E2F-5 ^², ³

Descriptions
E2F transcription factor 5 ^²
E2F transcription factor 5, p130-binding ^²

External Ids
HGNC: 3119¹
Entrez Gene: 1875²
UniProtKB: Q15329³
Ensembl: ENSG00000133740⁷

Search outside databases for aliases for E2F5 gene

Previous GC identifers: GC08P084913 GC08P086046 GC08P085869 GC08P086164

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for E2F5:

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F

family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins

and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins

contain several evolutionarily conserved domains that are present in most members of the family.

These domains include a DNA binding domain, a dimerization domain which determines interaction

with the differentiation regulated transcription factor proteins (DP), a transactivation domain

enriched in acidic amino acids, and a tumor suppressor protein association domain which is

embedded within the transactivation domain. This protein is differentially phosphorylated and is

expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family

members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not

with pRB. Alternative splicing results in multiple variants encoding different isoforms. [provided

by RefSeq]

UniProtKB/Swiss-Prot: E2F5_HUMAN, Q15329

Function: Transcriptional activator that binds to E2F sites, these sites are present in the

promoter of many genes whose products are involved in cell proliferation. May mediate growth

factor-initiated signal transduction. It is likely involved in the early responses of resting

cells to growth factor stimulation

Gene Wiki entry for E2F5

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the E2F5 gene

Entrez Gene cytogenetic band: 8q21.2 Ensembl cytogenetic band: 8q21.2 HGNC cytogenetic band: 8q21.2

E2F5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08P086276: (about GC identifiers)

Start:	86,276,871 bp from pter
End:	86,314,005 bp from pter
Size:	37,135 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000008.9 NT_008183.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: E2F5_HUMAN, Q15329 (See protein sequence)

Recommended Name: Transcription factor E2F5

Size: 346 amino acids; 37610 Da

Subunit: Component of the DRTF1/E2F transcription factor complex. Binds cooperatively with DP-1 to

E2F sites. Interaction with retinoblastoma protein RB1 or proteins RBL1 and RBL2 inhibits the E2F

transactivation domain. Component of the DREAM complex (also named LINC complex) at least composed

of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The

complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in

S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2

Subcellular location: Nucleus

Secondary accessions: Q16601 Q92756

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (3 alternative transcripts):

NP_001077057.1 NP_001077058.1 NP_001942.2

ENSEMBL proteins:

ENSP00000256117

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (E2F5)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005654	nucleoplasm	EXP	9190208
GO:0005667	transcription factor complex	IEA	--
GO:0005737	cytoplasm	IEA	--

About this table

Antibodies for E2F5:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for E2F5
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (E2F5), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for E2F5

Assays for E2F5:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q15329

ProtoNet protein and cluster: Q15329

1 Blocks protein family: IPB003316 Transcription factor E2F/dimerisation partner (TDP)

UniProtKB/Swiss-Prot: E2F5_HUMAN, Q15329

Similarity: Belongs to the E2F/DP family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (E2F5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (E2F5)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001083588

Applied Biosystems Silencer® siRNAs for E2F5

Sigma-Aldrich siRNA for E2F5

Sigma-Aldrich shRNA Panels and shRNA for E2F5

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001083588
Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001083588
untagged cDNA clones in CMV expression vector (see all 3): NM_001083588

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001951

UniProtKB/Swiss-Prot: E2F5_HUMAN, Q15329

Function: Transcriptional activator that binds to E2F sites, these sites are present in the

promoter of many genes whose products are involved in cell proliferation. May mediate growth

factor-initiated signal transduction. It is likely involved in the early responses of resting

cells to growth factor stimulation

10 MGI mutant phenotypes (inferred from 1 allele) (MGI details for E2f5):

	behavior/neurological	cellular	craniofacial	homeostasis/metabolism
lethality-prenatal/perinatal	life span-post-weaning/aging	nervous system	skeleton	skin/coat/nails

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	NAS	7892279
GO:0005515	protein binding	TAS	7760804

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/7 Sigma-Aldrich "Your Favorite Gene" Pathways for E2F5 (Your Favorite Gene powered by Ingenuity) (see all 7 )

Role of BRCA1 in DNA Damage Response
Cell Cycle Regulation by BTG Family Proteins
Cell Cycle: G1/S Checkpoint Regulation
Glioma Signaling
Role of CHK Proteins in Cell Cycle Checkpoint Control

GeneDecks E2F5 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for E2F5

5/28 Interacting proteins for E2F5 (ENSP00000256117³) via UniProtKB, MINT, and/or STRING (see all 28 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RBL1	ENSP00000362768³	STRING (score=.999)
RBL2	ENSP00000262133³	STRING (score=.999)
TFDP1	ENSP00000364519³	STRING (score=.999)
RB1	ENSP00000267163³	STRING (score=.996)
SMAD3	ENSP00000332973³	STRING (score=.995)

About this table

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006350	transcription	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0009887	organ morphogenesis	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for E2F5
1 Novoseek chemical compound relationship for E2F5 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
dihydrofolate	39.05	1	10823896 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (E2F5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (E2F5)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001083588

Sigma-Aldrich siRNA for E2F5

Sigma-Aldrich shRNA Panels and shRNA for E2F5

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001083588 NM_001083589 NM_001951

REFSEQ mRNAs for E2F5 gene (3 alternative transcripts):

NM_001083588.1 NM_001083589.1 NM_001951.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001083588 NM_001083589 NM_001951

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001083588
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001083588
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_001083588

Additional cDNA sequence:

CR599340.1 CR605094.1 U15642.1 U31556.1 X86097.1 Z78409.1

7 DOTS entries:

DT.91767898 DT.95165122 DT.95257961 DT.305579 DT.100813249 DT.86846772 DT.95165120

24/91 AceView cDNA sequences (see all 91 ):

AA766588 AA748780 BX117249 BM698762 BX091085 BF116070 AA455521 AW051475

BG282688 CR605094 AI066452 AA484938 AW589432 AA723164 BU735902 AA991290

CR599340 AI740797 X86097 BE878145 AI288540 BF740154 AW027851 Z78409

highest scoring ESTs for E2F5:

U15642 U31556 AA286972 AA455521 AA723164 AA743346 AA766588 AA978108 AA991290 AI066452

Unigene Cluster for E2F5:

E2F transcription factor 5, p130-binding

Hs.445758 [show with all ESTs]

Unigene Representative Sequence: X86097

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for E2F5

ExUns:	1	^	2	^	3	^	4	^	5a	·	5b	^	6a	·	6b	^	7a	·	7b
SP1:
SP2:
SP3:

About this scheme

ECgene alternative splicing isoforms for E2F5

1 Ensembl transcript including schematic representation:

ENST00000256117

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

E2F5 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for E2F5

¹ / ² / ³

6 probe-sets matching E2F5 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
41275_at²^{, 3}	U95-A	1	1.00	1.00	0.96	1.06	U31556	1.00	1.00	1.00	1
1044_s_at²^{, 3}	U95-A	1	1.00	1.00	0.92	1.00	U31556	1.00	1.00	1.00	1
1639_s_at²^{, 3}	U95-A	1	1.00	1.00	0.83	0.77	U15642	1.00	1.00	1.00	1
66404_at²^{, 3}	U95-C	1	1.00	1.00	0.35	1.19	AA748780	0.60	1.00	0.82	1
221586_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	U15642	1.00	1.00	1.00	1
221586_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks E2F5 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GAAACTTGGG

SOURCE GeneReport for Unigene cluster: Hs.445758
Expression variation in blood from EXPOLDB for E2F5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for E2F5 gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	E2F5¹	--	E2F transcription factor 5, p130-binding	89.81(n) 91.67(a)	611103 XM_848740.1 XP_853833.1
chimpanzee (Pan troglodytes)	E2F5¹	--	E2F transcription factor 5, p130-binding	99.9(n) 100(a)	747256 XM_001169141.1 XP_001169141.1
cow (Bos taurus)	E2F5¹	--	E2F transcription factor 5, p130-binding	90.94(n) 91.91(a)	539427 XM_587085.3 XP_587085.3
rat (Rattus norvegicus)	E2f5¹	--	E2F transcription factor 5	88.95(n) 90.24(a)	116651 XM_574892.2 XP_574892.1
mouse (Mus musculus)	E2f5^{1, 5}	3⁵	E2F transcription factor 5^{1, 5}	88.86(n)¹ 90.75(a)¹	13559¹ NM_007892.2¹ NP_031918.2¹ AK028856⁵ AK156760⁵ (see all 10)

About this table Species with no ortholog for E2F5

ENSEMBL Gene Tree for E2F5

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for E2F5 gene

E2F4² E2F6²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/190 NCBI SNPs in E2F5 are shown (see all 190 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 100)

AB	SNP ID	Valid	Chr 8 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs10100442^1,2	A,C,F,H	86275358(+)	`ATGTCA/GCTTCA`	2	--	ng5¹		4		EU EA WA	416
	rs4150867^1,2	A,C,F,H	86286794(+)	`ggttcG/Atttga`	3	--	int¹ ng5¹		13		NS EU EA WA NA	1218
	rs4150868^1,2	C,F,H	86286886(+)	`cccctG/Actatt`	3	--	int¹ ng5¹		14		NS EU EA WA NA	1382
--	rs4150862^1,2	A,C,F	86286041(+)	`atataT/Cataag`	3	--	int¹ ng5¹		1		NS	176
	rs4150873^1,2	C,F,H	86287194(+)	`GCAGCA/GTAAGT`	3	--	int¹ ut5¹		19		NS EU EA WA NA	1506
	rs4150869^1,2	C,F,H	86286953(+)	`aggtgT/Ctgcta`	3	--	int¹ ng5¹		5		NS EU EA WA	578
--	rs4150865^1,2	C,F	86286240(+)	`atggtG/Atatat`	3	--	int¹ ng5¹		1		NS	154
--	rs7842013^1,2	A,C	86285270(+)	`ttggaA/Gaaatg`	3	--	ng5¹ int¹		0	--	--	--	--
--	rs7838900^1,2	A,C	86285501(+)	`ctataC/Taccca`	3	--	int¹ ng5¹		0	--	--	--	--
--	rs4150866^1,2	F	86286295(+)	`GTATAT/AATAAG`	3	--	int¹ ng5¹		1		NS	154

About this table

HapMap Linkage Disequilibrium images for E2F5 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 600967

4 Novoseek disease relationships for E2F5 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
retinoblastoma	70.23	1	15548374 (1)
tumors	24.02	11	10738311 (3), 12368233 (1), 16721044 (1)
cancer	11.85	3	16721044 (1), 8622649 (1), 19014670 (1)
breast cancer	0.00	1	10738311 (1)

About this table

Human Genome Epidemiology Navigator: E2F5 (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/61 PubMed articles for E2F5 gene (see all 61 ):

E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle. (PubMed id 7892279)^{1, 2, 3, 4} Sardet C....Weinberg R.A. (1995)
The molecular and functional characterization of E2F-5 transcription factor. (PubMed id 9464260)^{1, 3, 4} Vaishnav Y.N.... Pant V. (1998)
Structural characterization and specificity of expression of E2F-5: a new member of the E2F family of transcription factors. (PubMed id 8589754)^{1, 3, 4} Itoh A....Mitsialis S.A. (1995)
E2F-5, a new E2F family member that interacts with p130 in vivo. (PubMed id 7760804)^{3, 4} Hijmans E.M....Bernards R. (1995)
Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators. (PubMed id 10783242)^{1, 3} Morris L....La Thangue N.B. (2000)
Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer. (PubMed id 19124506)³ Mavaddat N....Pharoah P.D. (2009)
Overexpression of E2F-5 correlates with a pathological basal phenotype and a worse clinical outcome. (PubMed id 19259095)³ Umemura S....Osamura Y.R. (2009)
Overexpression of E2F5/p130, but not E2F5 alone, can inhibit E2F-induced cell cycle entry in transgenic mice. (PubMed id 18385796)³ Chen Q....Overbeek P.A. (2008)
Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence. (PubMed id 17531812)⁴ Litovchick L.... DeCaprio J.A. (2007)
Induction of human metallothionein 1G promoter by VEGF and heavy metals: differential involvement of E2F and metal transcription factors. (PubMed id 15735762)³ Joshi B....Chellappan S. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 1875	HGNC: 3119	AceView: E2F5	Ensembl:ENSG00000133740	euGenes: HUgn1875
ECgene: E2F5	H-InvDB: E2F5

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for E2F5	Genetics and Cytogenetics in Oncology and Haematology
NIEHS-SNPs	http://egp.gs.washington.edu/data/e2f5/

Licensable Technologies for E2F5
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for E2F5:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for E2F5-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for E2F5		Antibodies for E2F5
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for E2F5		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Search for Recombinant Proteins
	Search for Antibodies
	Chimera RNAi (E2F5)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (E2F5)
	Antibodies (E2F5)

Search OriGene for E2F5

Search Tocris compounds for E2F5

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for E2F5

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
E2F5 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

E2F5 Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for E2F5

Summaries
for E2F5

Genomic Location
for E2F5

Proteins
for E2F5

Protein Domains/
Families
for E2F5

Gene Function
for E2F5

Pathways & Interactions
for E2F5

Drugs & Compounds
for E2F5

Transcripts
for E2F5

Expression
for E2F5

Orthologs
for E2F5

Paralogs
for E2F5

SNPs/Variants
for E2F5

Disorders & Mutations
for E2F5

Medical News
for E2F5

Publications
for E2F5

Search for E2F5

Genome Databases showing E2F5

Other Databases showing E2F5

Specialized Databases showing E2F5

Licensable Technologies
for E2F5

Services
for E2F5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

E2F5 Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor E2F5

Summariesfor E2F5

Genomic Locationfor E2F5

Proteinsfor E2F5

Protein Domains/Familiesfor E2F5

Gene Functionfor E2F5

Pathways & Interactionsfor E2F5

Drugs & Compoundsfor E2F5

Transcriptsfor E2F5

Expression for E2F5

Orthologsfor E2F5

Paralogsfor E2F5

SNPs/Variantsfor E2F5

Disorders & Mutationsfor E2F5

Medical Newsfor E2F5

Publicationsfor E2F5

Search for E2F5

Genome Databases showing E2F5

Other Databases showing E2F5

Specialized Databases showing E2F5

Licensable Technologiesfor E2F5

Servicesfor E2F5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for E2F5

Summaries
for E2F5

Genomic Location
for E2F5

Proteins
for E2F5

Protein Domains/
Families
for E2F5

Gene Function
for E2F5

Pathways & Interactions
for E2F5

Drugs & Compounds
for E2F5

Transcripts
for E2F5

Expression
for E2F5

Orthologs
for E2F5

Paralogs
for E2F5

SNPs/Variants
for E2F5

Disorders & Mutations
for E2F5

Medical News
for E2F5

Publications
for E2F5

Licensable Technologies
for E2F5

Services
for E2F5