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Aliases for DYTN Gene

Aliases for DYTN Gene

  • Dystrotelin 2 3

External Ids for DYTN Gene

Previous GeneCards Identifiers for DYTN Gene

  • GC02M207260
  • GC02M207516
  • GC02M199365

Summaries for DYTN Gene

GeneCards Summary for DYTN Gene

DYTN (Dystrotelin) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is DRP2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DYTN Gene

Genomics for DYTN Gene

Regulatory Elements for DYTN Gene

Genomic Location for DYTN Gene

206,651,621 bp from pter
206,718,396 bp from pter
66,776 bases
Minus strand

Genomic View for DYTN Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DYTN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DYTN Gene

Proteins for DYTN Gene

  • Protein details for DYTN Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:
    Secondary Accessions:

    Protein attributes for DYTN Gene

    578 amino acids
    Molecular mass:
    65320 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DYTN Gene

Proteomics data for DYTN Gene at MOPED

Post-translational modifications for DYTN Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for DYTN Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for DYTN Gene

Domains for DYTN Gene

Protein Domains for DYTN Gene

Suggested Antigen Peptide Sequences for DYTN Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • A2CJ06
  • Contains 1 ZZ-type zinc finger.
genes like me logo Genes that share domains with DYTN: view

No data available for Gene Families for DYTN Gene

Function for DYTN Gene

Gene Ontology (GO) - Molecular Function for DYTN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005509 calcium ion binding --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with DYTN: view

Phenotypes for DYTN Gene

GenomeRNAi human phenotypes for DYTN:
genes like me logo Genes that share phenotypes with DYTN: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for DYTN

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for DYTN Gene

Localization for DYTN Gene

Subcellular locations from UniProtKB/Swiss-Prot for DYTN Gene

Cell membrane.

Subcellular locations from

Jensen Localization Image for DYTN Gene COMPARTMENTS Subcellular localization image for DYTN gene
Compartment Confidence
cytosol 3
nucleus 2
plasma membrane 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for DYTN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
genes like me logo Genes that share ontologies with DYTN: view

Pathways for DYTN Gene

SuperPathways for DYTN Gene

No Data Available

Interacting Proteins for DYTN Gene

Gene Ontology (GO) - Biological Process for DYTN Gene


No data available for Pathways by source for DYTN Gene

Transcripts for DYTN Gene

mRNA/cDNA for DYTN Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DYTN Gene

Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for DYTN

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for DYTN Gene

No ASD Table

Relevant External Links for DYTN Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DYTN Gene

mRNA expression in normal human tissues for DYTN Gene

mRNA differential expression in normal tissues according to GTEx for DYTN Gene

This gene is overexpressed in Whole Blood (23.3).

Protein differential expression in normal tissues for DYTN Gene

This gene is overexpressed in Heart (50.5) and Adipocyte (18.5).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for DYTN Gene

SOURCE GeneReport for Unigene cluster for DYTN Gene Hs.640667

genes like me logo Genes that share expressions with DYTN: view

Expression partners for DYTN Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for DYTN Gene

Orthologs for DYTN Gene

This gene was present in the common ancestor of animals.

Orthologs for DYTN Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia DYTN 35
  • 81.03 (n)
  • 71.8 (a)
  • 61 (a)
(Canis familiaris)
Mammalia DYTN 35
  • 81.8 (n)
  • 71.75 (a)
  • 60 (a)
(Mus musculus)
Mammalia Dytn 35
  • 73.66 (n)
  • 60.66 (a)
Dytn 16
Dytn 36
  • 53 (a)
(Pan troglodytes)
Mammalia DYTN 35
  • 98.9 (n)
  • 97.57 (a)
  • 98 (a)
(Rattus norvegicus)
Mammalia Dytn 35
  • 72.6 (n)
  • 59.76 (a)
(Ornithorhynchus anatinus)
Mammalia DYTN 36
  • 5 (a)
(Gallus gallus)
Aves DYTN 35
  • 58.9 (n)
  • 46.61 (a)
  • 38 (a)
(Anolis carolinensis)
Reptilia DYTN 36
  • 30 (a)
(Danio rerio)
Actinopterygii dytn 36
  • 26 (a)
fruit fly
(Drosophila melanogaster)
Insecta Dys 36
  • 4 (a)
(Caenorhabditis elegans)
Secernentea dys-1 36
  • 3 (a)
Species with no ortholog for DYTN:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for DYTN Gene

Gene Tree for DYTN (if available)
Gene Tree for DYTN (if available)

Paralogs for DYTN Gene

Paralogs for DYTN Gene

genes like me logo Genes that share paralogs with DYTN: view

Variants for DYTN Gene

Sequence variations from dbSNP and Humsavar for DYTN Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs737124 -- 206,693,863(-) AGTGA(C/T)ACCAT intron-variant
rs1001110 -- 206,718,491(+) AGAAG(C/T)AGAGG upstream-variant-2KB
rs1001111 -- 206,718,682(+) AATAA(C/T)ACTAT upstream-variant-2KB
rs1012525 -- 206,672,949(-) tgtac(A/C)cctga intron-variant
rs1864265 -- 206,699,370(+) TGAAG(C/T)TGCAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DYTN Gene

Variant ID Type Subtype PubMed ID
nsv875739 CNV Gain 21882294

Relevant External Links for DYTN Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DYTN Gene

Disorders for DYTN Gene

Relevant External Links for DYTN

Human Genome Epidemiology (HuGE) Navigator

No disorders were found for DYTN Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for DYTN Gene

Publications for DYTN Gene

  1. The dystrotelin, dystrophin and dystrobrevin superfamily: new paralogues and old isoforms. (PMID: 17233888) Jin H. … Roberts R.G. (BMC Genomics 2007) 2 3 4

Products for DYTN Gene

Sources for DYTN Gene

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