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Aliases for DYTN Gene

Aliases for DYTN Gene

  • Dystrotelin 2 3 5

External Ids for DYTN Gene

Previous GeneCards Identifiers for DYTN Gene

  • GC02M207260
  • GC02M207516
  • GC02M199365

Summaries for DYTN Gene

GeneCards Summary for DYTN Gene

DYTN (Dystrotelin) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is DRP2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DYTN Gene

Genomics for DYTN Gene

Regulatory Elements for DYTN Gene

Enhancers for DYTN Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around DYTN on UCSC Golden Path with GeneCards custom track

Genomic Location for DYTN Gene

206,651,621 bp from pter
206,718,396 bp from pter
66,776 bases
Minus strand

Genomic View for DYTN Gene

Genes around DYTN on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DYTN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DYTN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DYTN Gene

Proteins for DYTN Gene

  • Protein details for DYTN Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:

    Protein attributes for DYTN Gene

    578 amino acids
    Molecular mass:
    65320 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DYTN Gene

Proteomics data for DYTN Gene at MOPED

Post-translational modifications for DYTN Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for DYTN Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for DYTN Gene

Domains & Families for DYTN Gene

Gene Families for DYTN Gene

Protein Domains for DYTN Gene

Suggested Antigen Peptide Sequences for DYTN Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 ZZ-type zinc finger.
  • Contains 1 ZZ-type zinc finger.
genes like me logo Genes that share domains with DYTN: view

Function for DYTN Gene

Phenotypes for DYTN Gene

GenomeRNAi human phenotypes for DYTN:
genes like me logo Genes that share phenotypes with DYTN: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DYTN Gene

Localization for DYTN Gene

Subcellular locations from UniProtKB/Swiss-Prot for DYTN Gene

Cell membrane.

Subcellular locations from

Jensen Localization Image for DYTN Gene COMPARTMENTS Subcellular localization image for DYTN gene
Compartment Confidence
plasma membrane 4
cytosol 3
nucleus 2
mitochondrion 1

No data available for Gene Ontology (GO) - Cellular Components for DYTN Gene

Pathways & Interactions for DYTN Gene

SuperPathways for DYTN Gene

No Data Available

Interacting Proteins for DYTN Gene

Gene Ontology (GO) - Biological Process for DYTN Gene


No data available for Pathways by source and SIGNOR curated interactions for DYTN Gene

Drugs & Compounds for DYTN Gene

No Compound Related Data Available

Transcripts for DYTN Gene

mRNA/cDNA for DYTN Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DYTN Gene

Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DYTN Gene

No ASD Table

Relevant External Links for DYTN Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DYTN Gene

mRNA expression in normal human tissues for DYTN Gene

mRNA differential expression in normal tissues according to GTEx for DYTN Gene

This gene is overexpressed in Whole Blood (x23.3).

Protein differential expression in normal tissues from HIPED for DYTN Gene

This gene is overexpressed in Heart (50.5) and Adipocyte (18.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for DYTN Gene

SOURCE GeneReport for Unigene cluster for DYTN Gene Hs.640667

genes like me logo Genes that share expression patterns with DYTN: view

Protein tissue co-expression partners for DYTN Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for DYTN Gene

Orthologs for DYTN Gene

This gene was present in the common ancestor of animals.

Orthologs for DYTN Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia DYTN 35
  • 81.03 (n)
  • 71.8 (a)
  • 61 (a)
(Canis familiaris)
Mammalia DYTN 35
  • 81.8 (n)
  • 71.75 (a)
  • 60 (a)
(Mus musculus)
Mammalia Dytn 35
  • 73.66 (n)
  • 60.66 (a)
Dytn 16
Dytn 36
  • 53 (a)
(Pan troglodytes)
Mammalia DYTN 35
  • 98.9 (n)
  • 97.57 (a)
  • 98 (a)
(Rattus norvegicus)
Mammalia Dytn 35
  • 72.6 (n)
  • 59.76 (a)
(Ornithorhynchus anatinus)
Mammalia DYTN 36
  • 5 (a)
(Gallus gallus)
Aves DYTN 35
  • 58.9 (n)
  • 46.61 (a)
  • 38 (a)
(Anolis carolinensis)
Reptilia DYTN 36
  • 30 (a)
(Danio rerio)
Actinopterygii dytn 36
  • 26 (a)
fruit fly
(Drosophila melanogaster)
Insecta Dys 36
  • 4 (a)
(Caenorhabditis elegans)
Secernentea dys-1 36
  • 3 (a)
Species with no ortholog for DYTN:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for DYTN Gene

Gene Tree for DYTN (if available)
Gene Tree for DYTN (if available)

Paralogs for DYTN Gene

Paralogs for DYTN Gene

genes like me logo Genes that share paralogs with DYTN: view

Variants for DYTN Gene

Sequence variations from dbSNP and Humsavar for DYTN Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs16838593 - 206,694,875(+) AGCGG(C/T)ATCTG reference, missense
rs2115591 - 206,663,116(+) TTTCT(G/T)TGGCA reference, missense
rs737124 -- 206,693,863(-) AGTGA(C/T)ACCAT intron-variant
rs1864265 -- 206,699,370(+) TGAAG(C/T)TGCAG intron-variant
rs2884769 -- 206,701,610(+) aagaa(G/T)agtgg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DYTN Gene

Variant ID Type Subtype PubMed ID
nsv875739 CNV Gain 21882294

Variation tolerance for DYTN Gene

Residual Variation Intolerance Score: 95.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.55; 77.88% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for DYTN Gene

Disorders for DYTN Gene

Relevant External Links for DYTN

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for DYTN Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DYTN Gene

Publications for DYTN Gene

  1. The dystrotelin, dystrophin and dystrobrevin superfamily: new paralogues and old isoforms. (PMID: 17233888) Jin H. … Roberts R.G. (BMC Genomics 2007) 2 3 4 67

Products for DYTN Gene

Sources for DYTN Gene