DYRK4 Gene
protein-coding GIFtS: 52
GCID: GC12P004699
|
|
dual-specificity tyrosine-(Y)-phosphorylation regulated...
| |
Aliases
for DYRK4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Dual-Specificity Tyrosine-(Y)-Phosphorylation Regulated Kinase 41 2 | | EC 2.7.12.13 8 | | Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase 42 | | EC 2.7.128 |
Export aliases for DYRK4 gene to outside databasesPrevious GC identifers: GC12P004436 GC12P004591 GC12P004569 |
Summaries
for DYRK4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for DYRK4:
Dual-specificity kinases, such as DYRK4, play key roles in cell proliferation, survival, and development (Zhang et al.,2005 (PubMed 15607427)).(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: DYRK4_HUMAN, Q9NR20Function: Possible non-essential role in spermiogenesis (By similarity)
|
Genomic Views
for DYRK4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009759.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DYRK4 gene promoter:
TBP Sox5 AML1a Nkx2-2 C/EBPalpha AREB6 FAC1 Nkx6-1 SEF-1 (1) Cart-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for DYRK4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DYRK4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12p13.32 Ensembl cytogenetic band: 12p13.32 HGNC cytogenetic band: 12p13.32DYRK4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P004699: view genomic region
(about GC identifiers)
Start:
|
4,671,370 bp from pter |
End:
|
4,723,325 bp from pter |
Size:
|
51,956 bases |
Orientation:
|
plus strand |
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Proteins
for DYRK4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DYRK4_HUMAN, Q9NR20 (See
protein sequence)Recommended Name: Dual specificity tyrosine-phosphorylation-regulated kinase 4 Size: 520 amino acids; 59608 Da
Cofactor: Magnesium (By similarity)
Subcellular location: Cytoplasm
Sequence caution: Sequence=AAF91393.1; Type=Erroneous initiation;
Secondary accessions: Q8NEF2 Q92631Alternative splicing: 2 isoforms: Q9NR20-1 Q9NR20-2 (May be due to a competing acceptor splice site. No experimental confirmation available)Explore the universe of human proteins at neXtProt for DYRK4: NX_Q9NR20
Post-translational modifications:
Autophosphorylated on tyrosine residues (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NR20
3 DME Specific Peptides for DYRK4 (Q9NR20)
DYRK4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003836.1
ENSEMBL proteins: ENSP00000437534 ENSP00000441996 ENSP00000444842 ENSP00000439168 ENSP00000441755 ENSP00000439697 ENSP00000438769 ENSP00000010132 ENSP00000446005
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005794 | Golgi apparatus |
IDA | -- |
DYRK4 for ontologies About GeneDecksing
DYRK4 Antibody Products:
Assay Products for DYRK4: |
Protein
Domains /
Families
for DYRK4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DYRK4 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NR20ProtoNet protein and cluster: Q9NR20 UniProtKB/Swiss-Prot: DYRK4_HUMAN, Q9NR20Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamilySimilarity: Contains 1 protein kinase domain |
Function
for DYRK4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: DYRK4_HUMAN, Q9NR20Function: Possible non-essential role in spermiogenesis (By similarity)Catalytic activity: ATP + a protein = ADP + a phosphoproteinEnzyme Numbers (IUBMB): EC 2.7.12.11 2 EC 2.7.122
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DYRK4 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DYRK4 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DYRK4 (NM_003845) | |  | Sino Biological Human cDNA Clone for DYRK4 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DYRK4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DYRK4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DYRK4 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004674 | protein serine/threonine kinase activity |
NAS | -- | | GO:0004712 | protein serine/threonine/tyrosine kinase activity |
IEA | -- | | GO:0004713 | protein tyrosine kinase activity |
IEA | -- | | GO:0005524 | ATP binding |
NAS | -- | | GO:0016301 | kinase activity |
-- | -- |
DYRK4 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for DYRK4:
Animal Models:
Mouse knock-out Dyrk4tm1Dgen for DYRK4
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Dyrk4):
DYRK4 for phenotypes About GeneDecksing
|
Pathways & Interactions
for DYRK4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DYRK4
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for DYRK4 (ENSP000000101324) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006468 | protein phosphorylation |
NAS | -- |
DYRK4 for ontologies About GeneDecksing
|
Drugs & Compounds
for DYRK4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DYRK4
3 HMDB Compounds for DYRK4 About this table
Search CenterWatch for drugs/clinical trials and news about DYRK4
|
Transcripts
for DYRK4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DYRK4 gene: NM_003845.1 Unigene Cluster for DYRK4: Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 Hs.439530 [show with all ESTs]Unigene Representative Sequence: GU13974318/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19): ENST00000542744(uc009zeh.1) ENST00000539701 ENST00000537719 ENST00000539309
ENST00000538520 ENST00000539490 ENST00000540757 ENST00000536157 ENST00000542905
ENST00000536645 ENST00000543431(uc001qmz.2 uc001qna.2 uc010ser.2)
ENST00000540644 ENST00000545571 ENST00000536137 ENST00000541024 ENST00000544671
ENST00000544050 ENST00000010132(uc001qmx.3 uc001qmy.2 uc021qtq.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DYRK4 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DYRK4 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: DYRK4 (NM_003845) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DYRK4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DYRK4 |
Additional cDNA sequence: AF263541.1 AK292322.1 AK298979.1 AK303744.1 AK308260.1 AK308702.1 AK311576.1 BC031244.1 GU139739.1 GU139740.1 GU139741.1 GU139742.1 GU139743.1 GU139744.1 GU139745.1 GU139746.1 Y09305.1 12 DOTS entries: DT.445124 DT.91746354 DT.100745792 DT.91746364 DT.121205606 DT.121205585 DT.121205675 DT.91667533 DT.91734568 DT.92066883 DT.95121205 DT.99961770 18 AceView cDNA sequences: AI829636 CR609016 AA968719 BX091456 BG057711 N55863 BC031244 NM_003845 W78116 N67478 AL561586 AA314672 CR615549 BM452073 AA481704 W79823 AL582755 W03407
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for DYRK4 (see all 13) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | - | | | | - | | - | | | | | | |
| SP2: | | | | | - | | - | | - | | - | | | | - | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | | | - | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 13a | · | 13b | · | 13c | ^ | 14 | ^ | 15a | · | 15b | · | 15c |
|---|
|
| SP1: | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | |
| SP3: | - | | | | | | | | | | | | | | |
| SP4: | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for DYRK4
|
Expression
for DYRK4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DYRK4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACCTCCCCAG
About this image
See DYRK4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DYRK4
SOURCE GeneReport for Unigene cluster: Hs.439530
SABiosciences Custom PCR Arrays for DYRK4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DYRK4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DYRK4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DYRK4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DYRK4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DYRK4 |
Orthologs
for DYRK4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for DYRK4 gene from 6/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
DYRK46 |
-- |
46(a) |
1 ↔ 1 |
5(80909936-80935850) |
zebrafish
(Danio rerio) |
Actinopterygii |
dyrk41 |
dual-specificity tyrosine-(Y)-phosphorylation regulated more |
61.33(n)
58.11(a) |
|
564976 XM_688297.4 XP_693389.3 |
fruit fly
(Drosophila melanogaster) |
Insecta |
smi35A1 , 3 |
olfaction protein serine/threonine kinase3
smell impaired 35A1 |
59(a)3
56.66(n)1
52.48(a)1 |
|
348311 NM_205989.21 NP_995711.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
C36B7.13 |
CDC2/CDC28 subfamily of ser/thr protein
kinases |
29(a)
(best of 2) |
|
X(7148145-7150119) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
YAK16 |
YAK1-like protein 1 |
16(a) |
possible ortholog |
5(14127984-14136324) |
rice
(Oryza sativa) |
Liliopsida |
Os.126532 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
79.19(n) |
|
AK100925.1 |
ENSEMBL Gene Tree for DYRK4 (if available)
TreeFam Gene Tree for DYRK4 (if available) |
Paralogs
for DYRK4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DYRK4 gene
- DYRK32 DYRK22 DYRK1A2 HIPK12 HIPK32 HIPK42 HIPK22 DYRK1B2
18/46 SIMAP similar genes for DYRK4 using alignment to 12 protein entries: DYRK4_HUMAN (see all proteins)
(see all similar genes):NDUFA9 CDK11B PRPF4B MAPK3 DYRK2 CDK10
CDK7 MAPK4 MAPK7 NLK DYRK3 CDK16
MAPK10 CSNK2A2 CDKL1 CDK12 MAPK9 DYRK1A
DYRK4 for paralogs About GeneDecksing
|
Genomic Variants
for DYRK4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DYRK4 (4671370 - 4723325 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for DYRK4
1 Inversion: 37136 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DYRK4 |
|
Disorders
/ Diseases
for DYRK4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DYRK4 for disorders About GeneDecksing
OMIM gene information: 609181
OMIM disorders: --
3  diseases for DYRK4: About MalaCardsrickets down syndrome malaria
1 disease from the University of Copenhagen DISEASES database for DYRK4:Down syndrome Export disorders for DYRK4 gene to outside databases
|
Publications
for DYRK4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DYRK4 gene integrated from 9 sources:
(articles sorted by number of sources associating them with DYRK4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases. (PubMed id 9748265)1, 2, 3 Becker W....Joost H.-G. (1998)
- The expression of the testis-specific Dyrk4 kinase is highly restricted to step 8 spermatids but is not required for male fertility in mice. (PubMed id 17292540)1, 2 Sacher F.... Fritsch M. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23. (PubMed id 11062477)1, 2 White K.E.... Strom T.M. (2000)
- Splice variants of the dual specificity tyrosine phosp horylation-regulated kinase 4 (DYRK4) differ in their subcellular localization a nd catalytic activity. (PubMed id 21127067)1 Papadopoulos C....de la Luna S. (2011)
- Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. (PubMed id 19953087)1 Persaud A....Rotin D. (2009)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)2 Greenman C.... Stratton M.R. (2007)
- DYRK gene structure and erythroid-restricted features of DYRK3 gene expression. (PubMed id 15607427)1 Zhang D....Wojchowski D.M. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for DYRK4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DYRK4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DYRK4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DYRK4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DYRK4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DYRK4 gene:
Search GeneIP for patents involving DYRK4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DYRK4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for DYRK4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DYRK4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DYRK4 | | | OriGene Protein Over-expression Lysate for DYRK4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DYRK4 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DYRK4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DYRK4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for DYRK4 | | OriGene Custom Protein Services for DYRK4 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DYRK4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DYRK4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DYRK4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DYRK4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DYRK4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DYRK4 |
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| | | | Search Tocris compounds for DYRK4 |
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 | | | DYRK4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DYRK4 |
|  |  |  | | | | ThermoFisher Antibodies for DYRK4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DYRK4 |
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