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DYNLT3 Gene

protein-coding   GIFtS: 54
GCID: GC0XM037696

Dynein, Light Chain, Tctex-Type 3

(Previous name: t-complex-associated-testis-expressed 1-like)
(Previous symbol: TCTE1L)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Dynein, Light Chain, Tctex-Type 31 2     TCTEX1L2
TCTE1L1 2 3 5     Dynein Light Chain Tctex-Type 32
Protein 91/232 3     TCTE1XL3
T-Complex-Associated-Testis-Expressed 1-Like1     T-Complex-Associated Testis-Expressed 1-Like3
RP32     

External Ids:    HGNC: 116941   Entrez Gene: 69902   Ensembl: ENSG000001651697   OMIM: 3003025   UniProtKB: P518083   

Export aliases for DYNLT3 gene to outside databases

Previous GC identifers: GC0XM037455 GC0XM037580 GC0XM035443


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DYNLT3 Gene:
This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the
light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding
dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function
independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and
20.(provided by RefSeq, Mar 2010)

GeneCards Summary for DYNLT3 Gene:
DYNLT3 (dynein, light chain, Tctex-type 3) is a protein-coding gene. Diseases associated with DYNLT3 include ornithine carbamoyltransferase deficiency, and herpes simplex. GO annotations related to this gene include motor activity and identical protein binding. An important paralog of this gene is DYNLT1.

UniProtKB/Swiss-Prot: DYLT3_HUMAN, P51808
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are
thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.
Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along
microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through
mitosis (By similarity)

Gene Wiki entry for DYNLT3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NC_018934.2  NT_079573.5  
Regulatory elements:
   Regulatory transcription factor binding sites in the DYNLT3 gene promoter:
         C/EBPbeta   AP-1   Lmo2   POU6F1 (c2)   C/EBPalpha   POU2F1   FOXJ2 (long isoform)   POU2F1a   FOXO1a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDYNLT3 promoter sequence
   Search Chromatin IP Primers for DYNLT3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DYNLT3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp21   Ensembl cytogenetic band:  Xp11.4   HGNC cytogenetic band: Xp21

DYNLT3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DYNLT3 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM037696:  view genomic region     (about GC identifiers)

Start:
37,696,010 bp from pter      End:
37,706,890 bp from pter
Size:
10,881 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: DYLT3_HUMAN, P51808 (See protein sequence)
Recommended Name: Dynein light chain Tctex-type 3  
Size: 116 amino acids; 13062 Da
Subunit: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of
non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains
(LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer
serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and
LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. DYNLT1 and DYNLT3 compete for
association with dynein IC (DYNC1I1 or DYNC1I2). Self-associates. Interacts with DYNC1I1 and DYNC1I2 (By
similarity). Interacts with BUB3. Interacts with SATB1 in nucleus to form complex with matrix attachment regions
(MARs) of DNA
Caution: Was originally (PubMed:8004092) thought to be a candidate for RP3
Secondary accessions: Q6ICS3

Explore the universe of human proteins at neXtProt for DYNLT3: NX_P51808

Explore proteomics data for DYNLT3 at MOPED


See DYNLT3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_006511.1  
ENSEMBL proteins: 
 ENSP00000367844   ENSP00000367841   ENSP00000402695  

DYNLT3 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
DYN: Cytoplasmic dyneins

1 InterPro protein domain:
 IPR005334 Tctex

Graphical View of Domain Structure for InterPro Entry P51808

ProtoNet protein and cluster: P51808

1 Blocks protein domain: IPB005334 Tctex-1 family

UniProtKB/Swiss-Prot: DYLT3_HUMAN, P51808
Similarity: Belongs to the dynein light chain Tctex-type family


DYNLT3 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: DYLT3_HUMAN, P51808
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are
thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.
Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along
microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through
mitosis (By similarity)

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003774motor activity IEA--
GO:0005515protein binding ----
GO:0042802identical protein binding IEA--
     
DYNLT3 for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for DYNLT3:
 Synthetic lethal with Ras 

Animal Models:
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Selected qRT-PCR Assays for microRNAs that regulate DYNLT3 (see all 27):
hsa-miR-125a-5p hsa-miR-448 hsa-miR-520e hsa-miR-302d hsa-miR-25 hsa-miR-302e hsa-miR-3142 hsa-miR-520a-3p
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
DYLT3_HUMAN, P51808: Nucleus. Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore. Note=Colocalizes with
BUB3 at kinetochores specifically during prometaphase
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytoskeleton5
nucleus5
plasma membrane4
cytosol3
extracellular2
mitochondrion1

Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0000776colocalizes with kinetochore IDA17289665
GO:0000777condensed chromosome kinetochore IEA--
GO:0005634nucleus IEA--
GO:0005737cytoplasm ----
GO:0005868cytoplasmic dynein complex IDA11425878

DYNLT3 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for DYNLT3 About                                                                                                See pathways by source

SuperPathContained pathways About
1Regulation of degradation of deltaF508 CFTR in CF
Regulation of degradation of deltaF508 CFTR in CF0.59
2Cytoplasmic microtubules
Cytoplasmic microtubules0.32
3Cell cycle Spindle assembly and chromosome separation
Cell cycle Spindle assembly and chromosome separation

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways


2 GeneGo (Thomson Reuters) Pathways for DYNLT3
    Cell cycle Spindle assembly and chromosome separation
Regulation of degradation of deltaF508 CFTR in CF


    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DYNLT3
Interactions:

    Search GeneGlobe Interaction Network for DYNLT3

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for DYNLT3 (P518082, 3 ENSP000003678414) via UniProtKB, MINT, STRING, and/or I2D (see all 66)
InteractantInteraction Details
GeneCardExternal ID(s)
DYNC1I2Q134092, 3, ENSP000003803084MINT-66315 I2D: score=5 STRING: ENSP00000380308
TESCQ96BS22, 3, ENSP000003763284MINT-67428 I2D: score=4 STRING: ENSP00000376328
CD5P061273, ENSP000003426814I2D: score=1 STRING: ENSP00000342681
DYNC1I1O145763, ENSP000003201304I2D: score=1 STRING: ENSP00000320130
BUB3O436843, ENSP000003578584I2D: score=2 STRING: ENSP00000357858
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Gene Ontology (GO): 3 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006810transport IEA--
GO:0007067mitosis IEA--
GO:0007346regulation of mitotic cell cycle ISS--

DYNLT3 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for DYNLT3 (DYLT3)

1 Novoseek inferred chemical compound relationship for DYNLT3 gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
ornithine 58.8 2 11581184 (1), 12011183 (1)



DYNLT3 for compounds           About GeneDecksing



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for DYNLT3 gene: 
NM_006520.2  

Unigene Cluster for DYNLT3:

Dynein, light chain, Tctex-type 3
Hs.446392  [show with all ESTs]
Unigene Representative Sequence: NM_006520
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000378581 ENST00000378578(uc004dds.3) ENST00000432389
miRNA
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Selected qRT-PCR Assays for microRNAs that regulate DYNLT3 (see all 27):
hsa-miR-125a-5p hsa-miR-448 hsa-miR-520e hsa-miR-302d hsa-miR-25 hsa-miR-302e hsa-miR-3142 hsa-miR-520a-3p
SwitchGear 3'UTR luciferase reporter plasmidDYNLT3 3' UTR sequence
Inhib. RNA
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Primer
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  QuantiTect SYBR Green Assays in human, mouse, rat DYNLT3
  QuantiFast Probe-based Assays in human, mouse, rat DYNLT3

Additional mRNA sequence: 

AK311851.1 BC000968.2 CR450320.1 CR542213.1 U02556.1 

4 DOTS entries:

DT.215099  DT.100786638  DT.100786643  DT.91797628 

Selected AceView cDNA sequences (see all 207):

BU190049 CB105131 AA583341 AV729307 AI167535 BP343409 BM973441 T17272 
BQ771757 CR622725 BU688171 AA384649 AL530244 CK820754 CB125998 BC000968 
BU676033 H11107 CR450320 AA385480 BI838609 CR591625 BM126476 CR615178 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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DYNLT3 expression in normal human tissues (normalized intensities)      DYNLT3 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CAGACTTGTT
DYNLT3 Expression
About this image


DYNLT3 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 5) fully expand
 
 Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
         Human embryonic stem cells (family)
 
 Endothelium (Cardiovascular System)
         Extraembryonic Angioblasts Extraembryonic Capillary Plexus
 
 Extraembryonic Mesoderm (Extraembryonic Tissues)
         Extraembryonic Angioblasts Extraembryonic Capillary Plexus
 
 Esophagus (Gastrointestinal Tract)
 
 Adrenal Gland (Endocrine System)
DYNLT3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

DYNLT3 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.446392
    Custom PCR Arrays for DYNLT3
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In Situ
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for DYNLT3 gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Dynlt31 , 5 dynein light chain Tctex-type 31, 5 86.49(n)1
90.52(a)1
  X (4.47 cM)5
671171  NM_025975.51  NP_080251.31 
 96542675 
chicken
(Gallus gallus)
Aves DYNLT31 dynein, light chain, Tctex-type 3 77.59(n)
79.31(a)
  418580  NM_001277734.1  NP_001264663.1 
lizard
(Anolis carolinensis)
Reptilia DYNLT36
dynein, light chain, Tctex-type 3
71(a)
1 ↔ 1
3(132249715-132263323)
tropical clawed frog
(Xenopus tropicalis)
Amphibia dynlt31 dynein, light chain, Tctex-type 3 68.71(n)
64.04(a)
  101732306  XM_004911750.1  XP_004911807.1 
zebrafish
(Danio rerio)
Actinopterygii Dr.48432 Danio rerio clone RK112A4H12 t-complex-associated-testis-expressed more 71.22(n)    AY398423.1 
worm
(Caenorhabditis elegans)
Secernentea dylt-16
Protein DYLT-1 (dylt-1) mRNA, complete cds
29(a)
1 ↔ 1
I(7300062-7300913) WBGene00008764


ENSEMBL Gene Tree for DYNLT3 (if available)
TreeFam Gene Tree for DYNLT3 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for DYNLT3 gene
DYNLT12  
5 SIMAP similar genes for DYNLT3 using alignment to 3 protein entries:     DYLT3_HUMAN (see all proteins):
FAM3A    FANCA    DYNLT1    CNOT2    ATL2

DYNLT3 for paralogs           About GeneDecksing


2 Pseudogenes.org Pseudogenes for DYNLT3
PGOHUM00000247453 PGOHUM00000240901


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for DYNLT3 (see all 209)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr X posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1929430441,2
--37614296(+) CTTGTA/TTTGTT 1 -- ds50010--------
rs1398975211,2
--37614611(+) TAACTA/GTTAAA 1 -- ds50010--------
rs1850875111,2
--37614945(+) AATATC/GAAACA 1 -- ut310--------
rs128491,2
C,F,A,H--37614970(-) TATTCT/ATGTAG 1 -- ut319Minor allele frequency- A:0.30MN NS EA NA CSA 794
rs1880275741,2
--37615007(+) CTAAGC/GTTATT 1 -- ut310--------
rs1917559441,2
--37615019(+) CTCTCC/TAAAAT 1 -- ut310--------
rs455607381,2
C--37615036(+) AGTTAC/TGGTTC 1 -- ut310--------
rs1839705331,2
--37615042(+) GGTTCC/TGCTCT 1 -- ut310--------
rs1138572661,2
C,F--37615043(+) GTTCCA/GCTCTC 1 -- ut311Minor allele frequency- G:0.00CSA 1
rs1882034071,2
--37615181(+) ATTACA/TTTTCA 1 -- ut310--------

HapMap Linkage Disequilibrium report for DYNLT3 (37696010 - 37706890 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for DYNLT3:    About this table    
Variant IDTypeSubtypePubMed ID
nsv515194CNV Loss21397061

Locus Specific Mutation Databases (LSDB): DYNLT3

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing DYNLT3
DNA2.0 Custom Variant and Variant Library Synthesis for DYNLT3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 300302    OMIM disorders: --

4 diseases for DYNLT3:    About MalaCards
ornithine carbamoyltransferase deficiency    herpes simplex    retinitis pigmentosa    retinitis

1 disease from the University of Copenhagen DISEASES database for DYNLT3:
Ornithine carbamoyltransferase deficiency

DYNLT3 for disorders           About GeneDecksing

1 Novoseek inferred disease relationship for DYNLT3 gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
retinitis pigmentosa 66.1 1 11581184 (1)


Export disorders for DYNLT3 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for DYNLT3 gene, integrated from 10 sources (see all 27):
(articles sorted by number of sources associating them with DYNLT3)
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  1. Identification of a gene from Xp21 with similarity to the tctex-1 gene of the murine t complex. (PubMed id 8004092)1, 2, 3 Roux A.-F.... Musarella M. (Hum. Mol. Genet. 1994)
  2. The DYNLT3 light chain directly links cytoplasmic dynein to a spindle checkpoint protein, Bub3. (PubMed id 17289665)1, 2 Lo K.W.... Pfister K.K. (J. Biol. Chem. 2007)
  3. Dynein light chain rp3 acts as a nuclear matrix-associated transcriptional modulator in a dynein-independent pathway. (PubMed id 16079286)1, 2 Yeh T.-Y.... Sung C.-H. (J. Cell Sci. 2005)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
  6. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
  7. Identification of the dynein light chains required for human papillomavirus infection. (PubMed id 21166973)1 Schneider M.A.... Lambert C. (Cell. Microbiol. 2011)
  8. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R.... Peters J.M. (Science 2010)
  9. Identification of binding domains in the herpes simplex virus type 1 small capsid protein pUL35 (VP26). (PubMed id 20668116)1 Apcarian A....Diefenbach R.J. (J. Gen. Virol. 2010)
  10. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Disorders
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  Query String
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OMIM
NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 6990 HGNC: 11694 AceView: TCTE1L Ensembl:ENSG00000165169 euGenes: HUgn6990
ECgene: DYNLT3 H-InvDB: DYNLT3

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for DYNLT3 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for DYNLT3 gene:
Search GeneIP for patents involving DYNLT3

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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