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DYNLL2 Gene

protein-coding   GIFtS: 53
GCID: GC17P056160

Dynein, Light Chain, LC8-Type 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Dynein, Light Chain, LC8-Type 21 2     Dlc22
8 KDa Dynein Light Chain B2 3     RSPH222
DLC8b2 3     Dynein Light Chain 2, Cytoplasmic2
DLC23 5     Radial Spoke 22 Homolog2
Radial Spoke 22 Homolog (Chlamydomonas)1     Dynein Light Chain LC8-Type 23
DNCL1B2     

External Ids:    HGNC: 245961   Entrez Gene: 1407352   Ensembl: ENSG000002643647   OMIM: 6089425   UniProtKB: Q96FJ23   

Export aliases for DYNLL2 gene to outside databases

Previous GC identifers: GC17P053516 GC17P051521


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for DYNLL2 Gene:
DYNLL2 (dynein, light chain, LC8-type 2) is a protein-coding gene. GO annotations related to this gene include cytoskeletal protein binding and motor activity. An important paralog of this gene is DNAL4.

UniProtKB/Swiss-Prot: DYL2_HUMAN, Q96FJ2
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are
thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.
Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along
microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By
similarity)

Gene Wiki entry for DYNLL2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the DYNLL2 gene promoter:
         STAT1   LHX3b/Lhx3b   AML1a   NRSF form 1   Lmo2   NF-kappaB   NRSF form 2   MZF-1   LHX3a/Lhx3a   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDYNLL2 promoter sequence
   Search Chromatin IP Primers for DYNLL2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DYNLL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q22   Ensembl cytogenetic band:  17q22   HGNC cytogenetic band: 17q23.2

DYNLL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DYNLL2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P056160:  view genomic region     (about GC identifiers)

Start:
56,160,776 bp from pter      End:
56,172,897 bp from pter
Size:
12,122 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DYL2_HUMAN, Q96FJ2 (See protein sequence)
Recommended Name: Dynein light chain 2, cytoplasmic  
Size: 89 amino acids; 10350 Da
Subunit: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of
non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains
(LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer
serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. Dynein ICs
and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. Interacts with DYNC1I1. Interacts
with BMF. Component of the myosin V motor complex. Interacts with rabies virus phosphoprotein (By similarity)
2 PDB 3D structures from and Proteopedia for DYNLL2:
2XQQ (3D)        3P8M (3D)    
Secondary accessions: B2R5B4

Explore the universe of human proteins at neXtProt for DYNLL2: NX_Q96FJ2

Explore proteomics data for DYNLL2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys36, Lys49
  • Modification sites at PhosphoSitePlus

  • See DYNLL2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_542408.1  
    ENSEMBL proteins: 
     ENSP00000477310  
    Reactome Protein details: Q96FJ2

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DYN: Cytoplasmic dyneins

    2 InterPro protein domains:
     IPR019763 Dynein_light_1/2_CS
     IPR001372 Dynein_light_chain_typ-1/2

    Graphical View of Domain Structure for InterPro Entry Q96FJ2

    ProtoNet protein and cluster: Q96FJ2

    1 Blocks protein domain: IPB001372 Dynein light chain

    UniProtKB/Swiss-Prot: DYL2_HUMAN, Q96FJ2
    Similarity: Belongs to the dynein light chain family


    Find genes that share domains with DYNLL2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DYL2_HUMAN, Q96FJ2
    Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are
    thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.
    Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along
    microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By
    similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003774motor activity IEA--
    GO:0005515protein binding ----
    GO:0008092cytoskeletal protein binding IEA--
         
    Find genes that share ontologies with DYNLL2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for DYNLL2:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DYNLL2
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    miRNA
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    miRTarBase miRNAs that target DYNLL2:
    hsa-mir-19b-3p (MIRT031095), hsa-mir-130b-3p (MIRT020140), hsa-mir-148a-3p (MIRT025997)

    Block miRNA regulation of human, mouse, rat DYNLL2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DYNLL2 (see all 48):
    hsa-miR-3685 hsa-miR-3938 hsa-miR-3194-5p hsa-miR-146a hsa-miR-938 hsa-miR-301a hsa-miR-639 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidDYNLL2 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DYNLL2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DYL2_HUMAN, Q96FJ2: Cytoplasm, cytoskeleton (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol4
    plasma membrane4
    nucleus2
    extracellular1

    Gene Ontology (GO): Selected cellular component terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005813centrosome IDA--
    GO:0005829cytosol TAS--
    GO:0005874microtubule IEA--
    GO:0005875microtubule associated complex ----

    Find genes that share ontologies with DYNLL2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for DYNLL2 About   (see all 8)  
    See pathways by source

    SuperPathContained pathways About
    1Activation of BH3-only proteins
    Activation of BH3-only proteins0.68
    Activation of BMF and translocation to mitochondria0.00
    Intrinsic Pathway for Apoptosis0.68
    2Regulation of degradation of deltaF508 CFTR in CF
    Regulation of degradation of deltaF508 CFTR in CF0.59
    3Class I MHC mediated antigen processing and presentation
    Adaptive Immune System0.41
    4CDK-mediated phosphorylation and removal of Cdc6
    Apoptosis0.38
    5Cytoplasmic microtubules
    Cytoplasmic microtubules0.32


    Find genes that share SuperPaths with DYNLL2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 GeneGo (Thomson Reuters) Pathways for DYNLL2
        Cell cycle Spindle assembly and chromosome separation
    Regulation of degradation of deltaF508 CFTR in CF

    2 Reactome Pathways for DYNLL2
        Activation of BMF and translocation to mitochondria
    MHC class II antigen presentation


    1 Kegg Pathway  (Kegg details for DYNLL2):
        Vasopressin-regulated water reabsorption

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DYNLL2
    Interactions:

        Search GeneGlobe Interaction Network for DYNLL2

    Selected Interacting proteins for DYNLL2 (Q96FJ22, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 59)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DNAL4O960152, 3MINT-66259 I2D: score=4 
    GPRIN2O602692, 3MINT-67893 I2D: score=4 
    THAP10Q9P2Z02, 3MINT-68009 I2D: score=4 
    ARL2P364043I2D: score=5 
    C12orf4Q9NQ893I2D: score=5 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport IEA--
    GO:0006915apoptotic process TAS--
    GO:0007017microtubule-based process IEA--
    GO:0008039synaptic target recognition IEA--
    GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II TAS--

    Find genes that share ontologies with DYNLL2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DYNLL2 (DYL2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DYNLL2 gene: 
    NM_080677.2  

    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000579991
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate DYNLL2 (see all 48):
    hsa-miR-3685 hsa-miR-3938 hsa-miR-3194-5p hsa-miR-146a hsa-miR-938 hsa-miR-301a hsa-miR-639 hsa-miR-3613-3p
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    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat DYNLL2
      QuantiFast Probe-based Assays in human, mouse, rat DYNLL2

    Selected AceView cDNA sequences (see all 36):

    AI719240 CD679355 W69788 AI992227 AF086304 AI201042 BF528423 NM_080677 
    W73755 BU731450 AA353512 AW852307 AI954150 AA435992 BG482221 AA534422 
    BG327828 BG479903 BM708057 BC010744 AA399997 BM700738 AA401429 AA298041 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DYNLL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTATGTCGC
    DYNLL2 Expression
    About this image

    DYNLL2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DYNLL2 Protein Expression
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DYNLL2 gene from Selected species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dynll21 , 5 dynein light chain LC8-type 21, 5 97.75(n)1
    100(a)1
      11 (52.35 cM)5
    680971  NM_026556.41  NP_080832.11 
     879795255 
    chicken
    (Gallus gallus)
    Aves DYNLL21 dynein, light chain, LC8-type 2 88.39(n)
    100(a)
      417663  XM_004946765.1  XP_004946822.1 
    lizard
    (Anolis carolinensis)
    Reptilia DYNLL26
    dynein, light chain, LC8-type 2
    100(a)
    1 ↔ 1
    GL344172.1(28066-46542)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.87192 Xenopus laevis transcribed sequence with strong similarity more 82.16(n)    48034616 
    zebrafish
    (Danio rerio)
    Actinopterygii BC059707.12   -- 84.48(n)    BC059707.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta ctp1 cut up 76.03(n)
    96.63(a)
      31405  NM_001258601.2  NP_001245530.1 
    worm
    (Caenorhabditis elegans)
    Secernentea dlc-11 dlc-1 82.4(n)
    95.51(a)
      175922  NM_066021.4  NP_498422.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DYN26
    Cytoplasmic light chain dynein, microtubule motor ...
    47(a)
    1 → many
    IV(1319387-1319841) YDR424C
    soybean
    (Glycine max)
    eudicotyledons 467223892   -- 74.87(n)  
    rice
    (Oryza sativa)
    Liliopsida AK107950.12   -- 77.89(n)    AK107950.1 


    ENSEMBL Gene Tree for DYNLL2 (if available)
    TreeFam Gene Tree for DYNLL2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DYNLL2 gene
    DNAL42  DYNLL12  
    4 SIMAP similar genes for DYNLL2 using alignment to 2 protein entries:     DYL2_HUMAN (see all proteins):
    DNCL1    DYNLL1    LOC392067    DNAL4

    Find genes that share paralogs with DYNLL2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DYNLL2 (see all 170)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1813409021,2
    C--56158842(+) CACAGA/CCTGGA 1 -- us2k10--------
    rs1476248761,2
    --56158873(+) TATTAC/TACTTC 1 -- us2k10--------
    rs1855837301,2
    --56158954(+) CATAGC/TAACCC 1 -- us2k10--------
    rs1424243111,2
    --56159019(+) CACACA/GGGCTA 1 -- us2k10--------
    rs1127299561,2
    C,F--56159224(+) ACAAGC/TCCTAA 1 -- us2k12Minor allele frequency- T:0.25CSA WA 120
    rs1164877591,2
    F--56159227(+) AGCCCT/GAAGTG 1 -- us2k11Minor allele frequency- G:0.04WA 118
    rs1479045161,2
    --56159233(+) AAGTGC/TATAAA 1 -- us2k10--------
    rs1489188111,2
    --56159251(+) TCCTCC/GTCTCC 1 -- us2k10--------
    rs1154544621,2
    C,F--56159260(+) CCCTCC/TCTTCC 1 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1881038181,2
    --56159301(+) ACACAA/GAGACT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DYNLL2 (56160776 - 56172897 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for DYNLL2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833497CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DYNLL2
    DNA2.0 Custom Variant and Variant Library Synthesis for DYNLL2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608942    OMIM disorders: --


    Find genes that share disorders with DYNLL2           About GenesLikeMe


    Export disorders for DYNLL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DYNLL2 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with DYNLL2)
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    1. Cytoplasmic dynein nomenclature. (PubMed id 16260502)1, 3 Pfister K.K....Vallee R.B. (J. Cell Biol. 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands. (PubMed id 14561217)1, 9 Day C.L....Hinds M.G. (Biochem. J. 2004)
    4. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    5. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    6. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    7. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    8. Viral immune modulators perturb the human molecular network by common and unique strategies. (PubMed id 22810585)1 Pichlmair A....Superti-Furga G. (Nature 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 140735 HGNC: 24596 AceView: Dlc2 Ensembl:ENSG00000264364 euGenes: HUgn140735
    ECgene: DYNLL2 Kegg: 140735 H-InvDB: DYNLL2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DYNLL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DYNLL2 gene:
    Search GeneIP for patents involving DYNLL2

    GeneCards and IP:
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