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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DYNC2LI1 Gene

protein-coding   GIFtS: 52
GCID: GC02P043913

Dynein, Cytoplasmic 2, Light Intermediate Chain 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Dynein, Cytoplasmic 2, Light Intermediate Chain 11 2
Dynein 2 Light Intermediate Chain2 3
D2LIC2 3
LIC32 3
Cytoplasmic Dynein 2 Light Intermediate Chain 12

External Ids:    HGNC: 245951   Entrez Gene: 516262   Ensembl: ENSG000001380367   UniProtKB: Q8TCX13   

Export aliases for DYNC2LI1 gene to outside databases

Previous GC identifer: GC02P043737


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for DYNC2LI1 Gene: 
DYNC2LI1 (dynein, cytoplasmic 2, light intermediate chain 1) is a protein-coding gene. Diseases associated with DYNC2LI1 include situs inversus, and otitis media, and among its related super-pathways are Immune System and Cytoskeleton remodeling Neurofilaments. GO annotations related to this gene include motor activity.

UniProtKB/Swiss-Prot: DC2L1_HUMAN, Q8TCX1
Function: May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_022184.15  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DYNC2LI1 gene promoter:
         COUP-TF1   AML1a   COUP   FOXO3   HNF-4alpha2   HNF-4alpha1   FOXO3b   COUP-TF   HNF-1   FOXO3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDYNC2LI1 promoter sequence
   Search SABiosciences Chromatin IP Primers for DYNC2LI1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DYNC2LI1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p25.1-p24.1   Ensembl cytogenetic band:  2p21   HGNC cytogenetic band: 2p25.1-p24.1

DYNC2LI1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DYNC2LI1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P043913:  view genomic region     (about GC identifiers)

Start:
44,001,178 bp from pter      End:
44,037,149 bp from pter
Size:
35,972 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DC2L1_HUMAN, Q8TCX1 (See protein sequence)
Recommended Name: Cytoplasmic dynein 2 light intermediate chain 1  
Size: 351 amino acids; 39625 Da
Subunit: The cytoplasmic dynein complex 2 is probably composed by a DYNC2H1 homodimer and a number of DYNC2LI1
light intermediate chains (By similarity)
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme (By similarity). Cytoplasm (By similarity).
Note=Localizes to the apical cytoplasm (By similarity)
Sequence caution: Sequence=AAD34055.1; Type=Frameshift; Positions=163, 167;
Secondary accessions: A8MVJ5 Q53F57 Q6PDB2 Q8IWA3 Q96B03 Q96J00 Q9Y370 Q9Y3S9
Alternative splicing: 5 isoforms:  Q8TCX1-1   Q8TCX1-2   Q8TCX1-3   Q8TCX1-4   Q8TCX1-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DYNC2LI1: NX_Q8TCX1

Explore proteomics data for DYNC2LI1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8TCX1

  • DYNC2LI1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DYNC2LI1 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001180393.1  NP_056337.1  NP_057092.2  

    ENSEMBL proteins: 
     ENSP00000260605   ENSP00000430356   ENSP00000385738   ENSP00000430525   ENSP00000381804  
     ENSP00000474032   ENSP00000428082   ENSP00000367850   ENSP00000388941  
    Reactome Protein details: Q8TCX1
    Human Recombinant Protein Products for DYNC2LI1: 
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    Cloud-Clone Corp. Proteins for DYNC2LI1 

    Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0005858axonemal dynein complex ISS12802074
    GO:0005881colocalizes with cytoplasmic microtubule ISS--
    GO:0005932colocalizes with microtubule basal body ISS12802074
    GO:0030990colocalizes with intraflagellar transport particle ISS--

    DYNC2LI1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    DYN: Cytoplasmic dyneins

    2 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR022780 Dynein_light_int_chain

    Graphical View of Domain Structure for InterPro Entry Q8TCX1

    ProtoNet protein and cluster: Q8TCX1

    UniProtKB/Swiss-Prot: DC2L1_HUMAN, Q8TCX1
    Similarity: Belongs to the dynein light intermediate chain family


    DYNC2LI1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DC2L1_HUMAN, Q8TCX1
    Function: May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis (By
    similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003774motor activity IEA--
    GO:0005515protein binding IPI--
         
    DYNC2LI1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for DYNC2LI1:
     Increased gamma-H2AX phosphory 

         6 MGI mutant phenotypes (inferred from 1 allele(MGI details for Dync2li1):
     cardiovascular system  embryogenesis  homeostasis/metabolism  limbs/digits/tail  mortality/aging 
     nervous system 

    DYNC2LI1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Dync2li1tm1Aar for DYNC2LI1

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    SwitchGear 3'UTR luciferase reporter plasmidDYNC2LI1 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DYNC2LI1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Immune System
    Immune System0.56
    Adaptive Immune System0.56
    2Cytoskeleton remodeling Neurofilaments
    Cytoplasmic microtubules0.32
    3MHC class II antigen presentation
    MHC class II antigen presentation0.32
    4Vasopressin-regulated water reabsorption
    Vasopressin-regulated water reabsorption

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for DYNC2LI1
        Cytoplasmic microtubules


    3        Reactome Pathways for DYNC2LI1
        Adaptive Immune System
    Immune System
    MHC class II antigen presentation


    1         Kegg Pathway  (Kegg details for DYNC2LI1):
        Vasopressin-regulated water reabsorption


    DYNC2LI1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DYNC2LI1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/61 Interacting proteins for DYNC2LI1 (Q8TCX12, 3 ENSP000002606054) via UniProtKB, MINT, STRING, and/or I2D (see all 61)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SOD1P004412, 3, ENSP000002701424MINT-8141655 MINT-8141681 MINT-8141720 MINT-8141617 I2D: score=1 STRING: ENSP00000270142
    DCTN1Q142032, 3, ENSP000003547914MINT-8141655 MINT-8141681 MINT-8141769 I2D: score=1 STRING: ENSP00000354791
    BAG3O958172, ENSP000003580814MINT-8141655 MINT-8141681 MINT-8141617 MINT-8141574 STRING: ENSP00000358081
    DYNC2H1Q8NCM83, ENSP000003811674I2D: score=2 STRING: ENSP00000381167
    DYNC1H1Q142043, ENSP000003489654I2D: score=1 STRING: ENSP00000348965
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007368determination of left/right symmetry IEA--
    GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II TAS--
    GO:0042384cilium assembly IEA--

    DYNC2LI1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DYNC2LI1 (DC2L1)

    Search CenterWatch for drugs/clinical trials and news about DYNC2LI1 / DC2L1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DYNC2LI1 gene (4 alternative transcripts): 
    NM_001012665.1  NM_001193464.1  NM_015522.3  NM_016008.3  

    Unigene Cluster for DYNC2LI1:

    Dynein, cytoplasmic 2, light intermediate chain 1
    Hs.371597  [show with all ESTs]
    Unigene Representative Sequence: BC040558
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000260605(uc002rtl.3 uc002rtk.3 uc010ynz.2) ENST00000496980
    ENST00000406852(uc002rth.3) ENST00000479242 ENST00000398823(uc002rti.3)
    ENST00000489222 ENST00000605786 ENST00000462426 ENST00000378587(uc021vgq.1)
    ENST00000482738 ENST00000443170
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    Additional mRNA sequence: 

    AF151818.1 AK074206.1 AK223432.1 AK301489.1 AL050006.1 AY083346.1 BC006969.1 BC016324.1 
    BC035126.1 BC040558.1 BC058823.1 

    15 DOTS entries:

    DT.214136  DT.91749508  DT.75100391  DT.429829  DT.100781420  DT.95093714  DT.91749506  DT.91749510 
    DT.91749504  DT.100716541  DT.40131772  DT.86855215  DT.91845495  DT.120987498  DT.75129730 

    24/208 AceView cDNA sequences (see all 208):

    AA633343 AI920989 BQ432334 AI985163 AI342230 NM_016008 AI802282 BQ787216 
    AI253766 AA436488 AA826115 BE349047 AA450294 AI809986 AW169765 BM764146 
    BU162322 NM_015522 AW001662 AI279853 BQ786938 AY083346 AI913130 AK074206 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for DYNC2LI1 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15a · 15b
    SP1:                          -                             -     -           -                             -                       -               
    SP2:                          -                             -     -           -                             -                       -               
    SP3:                                                        -     -           -                                                                     
    SP4:                                                                          -                             -                                       
    SP5:                                                                                                        -                                       


    ECgene alternative splicing isoforms for DYNC2LI1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DYNC2LI1 expression in normal human tissues (normalized intensities)      DYNC2LI1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCACTCACC
    DYNC2LI1 Expression
    About this image


    DYNC2LI1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Pancreas (Endocrine System)
             Posterior foregut-like cells ( A scalable, suspension protocol for derivation of...
     
     Testis (Reproductive System)
     
     Kidney (Urinary System)

     -- (Endocrine System)
             pituitary gland   

    See DYNC2LI1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DYNC2LI1

    SOURCE GeneReport for Unigene cluster: Hs.371597
        SABiosciences Expression via Pathway-Focused PCR Array including DYNC2LI1: 
              Primary Cilia in human mouse rat

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for DYNC2LI1 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dync2li11 , 5 dynein cytoplasmic 2 light intermediate chain 11, 5 83.95(n)1
    87.75(a)1
      17 (55.02 cM)5
    2135751  NM_172256.11  NP_758460.11 
     846264965 
    chicken
    (Gallus gallus)
    Aves DYNC2LI11 dynein, cytoplasmic 2, light intermediate chain 1 73.1(n)
    66.28(a)
      421400  XM_419456.3  XP_419456.3 
    lizard
    (Anolis carolinensis)
    Reptilia DYNC2LI16
    dynein, cytoplasmic 2, light intermediate chain 1
    69(a)
    1 ↔ 1
    GL343231.1(1756081-1793562)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc636732 hypothetical protein MGC63673 75.45(n)   393452  BC055198.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG37691 CG3769 45.06(n)
    35.86(a)
      34262  NM_135445.2  NP_609289.1 
    worm
    (Caenorhabditis elegans)
    Secernentea xbx-11 Protein XBX-1 50.51(n)
    37.42(a)
      184080  NM_074282.2  NP_506683.2 


    ENSEMBL Gene Tree for DYNC2LI1 (if available)
    TreeFam Gene Tree for DYNC2LI1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DYNC2LI1 gene
    18/91 SIMAP similar genes for DYNC2LI1 using alignment to 6 protein entries:     DC2L1_HUMAN (see all proteins) (see all similar genes):
    KIAA0101    LDLRAD3    RRM2B    SEPSECS    AGBL3    NXPE2
    FLJ00047    NLRC5    ARIH1    ARL6IP5    BIRC3    EIF3G
    C12orf76    SEC14L3    TNNT1    ZNF559    pp12301    NDC80

    DYNC2LI1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1012 SNPs in DYNC2LI1 are shown (see all 1012)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs7252381,2
    C,F,O,A,H--43999182(-) TGGTGG/AAGCTA 3 -- us2k1112Minor allele frequency- A:0.28NS EA NA PA EU CA WA CSA 8616
    rs413617441,2
    C,F--43999204(+) TGATCG/ACAACC 3 -- us2k17Minor allele frequency- A:0.05NS EA NA WA 548
    rs1853966171,2
    --43999251(+) CCTTTA/TCCCTT 3 -- us2k10--------
    rs104959081,2
    C,F,H--43999312(+) TCCTTC/TCATTC 3 -- us2k1 trp389Minor allele frequency- T:0.04NS EA PA EU CA WA NA 4740
    rs38347871,2
    C--43999332(-) TGAAG-/ATTGTTC 3 -- us2k10--------
    rs2005317951,2
    C--43999332(-) GAAGAG/TTGTTC 3 -- us2k10--------
    rs23745741,2
    C,F,A,H--43999558(+) GTACTC/AGTACT 3 -- us2k112Minor allele frequency- A:0.39NS EA NA WA CSA 785
    rs1905904001,2
    --43999678(+) CTAGAA/CCCCAA 3 -- us2k10--------
    rs1820653301,2
    --43999691(+) CATTAA/CAATTC 3 -- us2k10--------
    rs37625711,2
    C,F,A,H--43999734(-) GCCAGA/CCTTTA 3 -- us2k129Minor allele frequency- C:0.32EA NA NS WA CSA 4392

    HapMap Linkage Disequilibrium report for DYNC2LI1 (44001178 - 44037149 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for DYNC2LI1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv873978CNV Loss21882294
    nsv873980CNV Loss21882294
    nsv873979CNV Loss21882294
    dgv59n68CNV Gain17160897
    nsv457174CNV Gain19166990

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    3 diseases for DYNC2LI1:    About MalaCards
    situs inversus    otitis media    neuronitis

    1 disease from the University of Copenhagen DISEASES database for DYNC2LI1:
    Situs inversus

    DYNC2LI1 for disorders           About GeneDecksing


    Export disorders for DYNC2LI1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DYNC2LI1 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with DYNC2LI1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel light intermediate chain (D2LIC) for mammalian cytoplasmic dynein 2. (PubMed id 11907264)1, 2, 3 Grissom P.M.... McIntosh J.R. (2002)
    2. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.H....Lin W. (2000)
    3. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    4. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    5. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    8. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    10. A novel dynein light intermediate chain colocalizes w ith the retrograde motor for intraflagellar transport at sites of axoneme assem bly in chlamydomonas and Mammalian cells. (PubMed id 12802074)1 Perrone C.A....Porter M.E. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51626 HGNC: 24595 AceView: D2LIC Ensembl:ENSG00000138036 euGenes: HUgn51626
    ECgene: DYNC2LI1 Kegg: 51626 H-InvDB: DYNC2LI1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DYNC2LI1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DYNC2LI1 gene:
    Search GeneIP for patents involving DYNC2LI1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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