DYNC2H1 Gene
protein-coding GIFtS: 53
GCID: GC11P102980
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dynein, cytoplasmic 2, heavy chain 1(Previous names: dynein, cytoplasmic, heavy polypeptide 2 ) (Previous symbol: DNCH2)
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Aliases for DYNC2H1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Dynein, Cytoplasmic 2, Heavy Chain 11 2 | | Dynein Heavy Chain Isotype 1B2 3 | | DHC21 2 3 5 | | ATD32 5 | | DNCH21 2 3 5 | | SRPS2B2 | | DYH1B1 2 3 | | Cytoplasmic Dynein 2 Heavy Chain 12 | | DHC1b1 2 | | Dynein Heavy Chain, Isotype 1B2 | | Dynein, Cytoplasmic, Heavy Polypeptide 21 2 | | DHC1B3 | | Hdhc111 | | KIAA19973 | | Dynein Cytoplasmic Heavy Chain 22 3 | | Cytoplasmic Dynein 2 Heavy Chain3 | | Dynein Heavy Chain 112 3 | | HDHC111 |
Export aliases for DYNC2H1 gene to outside databasesPrevious GC identifers: GC11P102487 GC11P098908 |
Summaries for DYNC2H1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for DYNC2H1: This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has arole in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause aheterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly,abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encodingdistinct proteins. (provided by RefSeq, Jan 2010) UniProtKB/Swiss-Prot: DYHC2_HUMAN, Q8NCM8Function: May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis. May play arole in transport between endoplasmic reticulum and Golgi or organization of the Golgi in cells (By similarity) Gene Wiki entry for DYNC2H1
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Genomic Views for DYNC2H1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the DYNC2H1 gene promoter: c-Fos AP-1 ATF-2 NF-AT CRE-BP1 CREB NF-AT2 c-Jun NF-AT1 RSRFC4 Other transcription factors
Search SABiosciences Chromatin IP Primers for DYNC2H1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DYNC2H1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q21-q22.1 Ensembl cytogenetic band: 11q22.3 HGNC cytogenetic band: 11q21-q22.1DYNC2H1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P102980: view genomic region
(about GC identifiers)
Start:
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102,980,160 bp from pter |
End:
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103,350,591 bp from pter |
Size:
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370,432 bases |
Orientation:
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plus strand |
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Proteins for DYNC2H1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: DYHC2_HUMAN, Q8NCM8 (See
protein sequence)Recommended Name: Cytoplasmic dynein 2 heavy chain 1 Size: 4307 amino acids; 492622 Da
Subunit: The cytoplasmic dynein complex 2 is probably composed by a heavy chain DYNC2H1 homodimer and a number ofDYNC2LI1 light intermediate chains (By similarity)
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme (By similarity). Cell membrane; Peripheral membraneprotein (By similarity). Cytoplasm (By similarity). Note=Localizes to the apical cytoplasm (By similarity). Accordingto PubMed:8666668, it localizes to Golgi apparatus, cytoplasmic vesicle and endoplasmic reticulum
Sequence caution: Sequence=BAB13905.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAC04578.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAD18598.1;Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: O00432 Q16693 Q3C1U8 Q4AC93 Q6ZMX7 Q6ZUM6 Q7Z363 Q8N977 Q92815 Q9HAE4Alternative splicing: 3 isoforms: Q8NCM8-1 Q8NCM8-2 Q8NCM8-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for DYNC2H1: NX_Q8NCM8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NCM8 DYNC2H1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001073932.1 NP_001368.2 ENSEMBL proteins: ENSP00000364887 ENSP00000334021 ENSP00000381167 ENSP00000433451 ENSP00000436736 Reactome Protein details: Q8NCM8 Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
DYNC2H1 for ontologies About GeneDecksing
DYNC2H1 Antibody Products: Assay Products for DYNC2H1: |
Protein
Domains / Families for DYNC2H1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DYNC2H1 for domains About GeneDecksing
5/9 InterPro domains/families (see all 9):Graphical View of Domain Structure for InterPro Entry Q8NCM8ProtoNet protein and cluster: Q8NCM8 UniProtKB/Swiss-Prot: DYHC2_HUMAN, Q8NCM8Similarity: Belongs to the dynein heavy chain family |
Function for DYNC2H1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: DYHC2_HUMAN, Q8NCM8Function: May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis. May play arole in transport between endoplasmic reticulum and Golgi or organization of the Golgi in cells (By similarity)
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DYNC2H1 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
DYNC2H1 for ontologies About GeneDecksing
Animal Models: 12 MGI mutant phenotypes (inferred from 5 alleles ) (MGI details for Dync2h1):
DYNC2H1 for phenotypes About GeneDecksing
|
Pathways & Interactions for DYNC2H1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
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| 1 | Immune System | | | 2 | MHC class II antigen presentation | | | 3 | Vasopressin-regulated water reabsorption | | | 4 | Phagosome | | | 5 | Cytoskeleton remodeling Neurofilaments | |
Pathway sources See GeneCards unified pathways Show all pathways
1 EMD Millipore Pathway for DYNC2H1
4
Reactome Pathways for DYNC2H1
2
Kegg Pathways (Kegg details for DYNC2H1):
DYNC2H1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DYNC2H1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/61 Interacting proteins for DYNC2H1 (Q8NCM83 ENSP000003811674) via UniProtKB, MINT, STRING, and/or I2D (see all 61)About this table
Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table
DYNC2H1 for ontologies About GeneDecksing
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Drugs & Compounds for DYNC2H1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for DYNC2H1 Search CenterWatch for drugs/clinical trials and news about DYNC2H1 / DYHC2 
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Transcripts for DYNC2H1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for DYNC2H1 gene (3 alternative transcripts): NM_001080463.1 NM_001377.2 NM_024606.2 Unigene Cluster for DYNC2H1: Dynein, cytoplasmic 2, heavy chain 1 Hs.503721 [show with all ESTs]Unigene Representative Sequence: NM_0010804639 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000375735(uc001phn.1 uc001pho.2 uc009yxe.1) ENST00000334267 ENST00000398093 ENST00000533027 ENST00000525306 ENST00000528670 ENST00000533197 ENST00000530547 ENST00000527252
Additional cDNA sequence: AB082528.2 AB231765.1 AB231766.1 AB290167.1 AF288405.1 AK021818.1 AK095579.1 AK125524.1 AK131453.1 BC038344.1 BX538093.1 BX649161.1 U20552.1 U53531.1 Z83800.1 6 DOTS entries: DT.40194787 DT.209797 DT.100693366 DT.95278970 DT.97770434 DT.101981168 5 AceView cDNA sequences: U20552 U53531 R64727 R64728 Z83800 GeneLoc Exon Structure
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Expression for DYNC2H1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DYNC2H1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TGGTCAGTCT
About this image See DYNC2H1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for DYNC2H1
SOURCE GeneReport for Unigene cluster: Hs.503721 SABiosciences Custom PCR Arrays for DYNC2H1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DYNC2H1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DYNC2H1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DYNC2H1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DYNC2H1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DYNC2H1 |
Orthologs for DYNC2H1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for DYNC2H1 gene from 5/23 species (see all 23) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
DYNC2H11 |
dynein, cytoplasmic 2, heavy chain 1 |
77.48(n) 79.89(a) |
  |
418979 XM_417173.3 XP_417173.2 |
lizard (Anolis carolinensis) |
Reptilia |
DYNC2H16 |
-- |
85(a) |
1 ↔ 1 |
3(191763083-191921617) |
zebrafish (Danio rerio) |
Actinopterygii |
BI864255.12 |
-- |
73.63(n) |
  |
BI864255.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
btv6 |
beethoven |
32(a) |
1 ↔ 1 |
2L(17962735-17982472) |
worm (Caenorhabditis elegans) |
Secernentea |
che-31 |
Protein CHE-3 |
51.6(n) 42(a) |
  |
172593 NM_059820.2 NP_492221.2 |
ENSEMBL Gene Tree for DYNC2H1 (if available) TreeFam Gene Tree for DYNC2H1 (if available)  |
Paralogs for DYNC2H1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for DYNC2H1 gene
- DNAH52 DNAH22 DNAH82 DYNC1H12 DNAH92 DNAH32 DNAH112 DNAH62
- DNAH72 DNAH12 DNAH102 DNAH172
8 SIMAP similar genes for DYNC2H1 using alignment to 4 protein entries: DYHC2_HUMAN (see all proteins):Dnchc1 DNAH5 Dnahc3 DNAH14 Dnahc9 Dnahc11 DNAH2 DNAH1
DYNC2H1 for paralogs About GeneDecksing
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Genomic Variants for DYNC2H1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 11 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
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HapMap Linkage Disequilibrium report for DYNC2H1 (102980160 - 103230160 bp, first 250kb of DYNC2H1)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 15 variations for DYNC2H1 7 CNVs: 0155 2954 71374 6896 8694 85985 85983 8 Indels: 44806 39859 60060 11575 39860 60059 101324 41661 Human Gene Mutation Database (HGMD): DYNC2H1
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DYNC2H1 |
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Disorders
/ Diseases for DYNC2H1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DYNC2H1 for disorders About GeneDecksing
OMIM gene information: 603297 OMIM disorders: 613091 263510 263520 UniProtKB/Swiss-Prot: DYHC2_HUMAN, Q8NCM8
Defects in DYNC2H1 are the cause of asphyxiating thoracic dystrophy type 3 (ATD3) [MIM:613091]. ATD3 is anautosomal recessive osteochondrodysplasia which often leads to death in infancy because of a severely constrictedthoracic cage and respiratory insufficiency Defects in DYNC2H1 are the cause of short rib-polydactyly syndrome type 3 (SRPS3) [MIM:263510]; also calledVerma-Naumoff syndrome. A lethal skeletal dysplasia characterized by markedly short ribs, short limbs, polydactyly,narrow thorax, and multiple anomalies of major organs, including heart, intestines, genitalia, kidney, liver, andpancreas 13 diseases for DYNC2H1: About MalaCardsshort rib-polydactyly syndrome, type ii, digenic polydactyly short rib-polydactyly syndrome type 3 ellis-van creveld syndrome asphyxiating thoracic dystrophy asphyxiating thoracic dystrophy 3 primary ciliary dyskinesia ciliary dyskinesia sensenbrenner syndrome osteochondrodysplasia malignant glioma lung cancer neuronitis 3 diseases from the University of Copenhagen DISEASES database for DYNC2H1:Asphyxiating thoracic dystrophy Polydactyly Sensenbrenner syndrome Human Genome Epidemiology (HuGE) Navigator: DYNC2H1 (2 documents) Export disorders for DYNC2H1 gene to outside databases
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Publications for DYNC2H1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DYNC2H1 gene, integrated from 9 sources (see all 30): (articles sorted by number of sources associating them with DYNC2H1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene. (PubMed id 9373155)1, 2, 3 Neesen J.... Schmid M. (1997)
- Ciliary abnormalities due to defects in the retrograde transport protein DYNC2H1 in short-rib polydactyly syndrome. (PubMed id 19361615)1, 2, 9 Merrill A.E....Krakow D. (2009)
- DYNC2H1 mutations cause asphyxiating thoracic dystrophy and short rib-polydactyly syndrome, type III. (PubMed id 19442771)1, 2, 9 Dagoneau N....Cormier-Daire V. (2009)
- Genetic analysis of the cytoplasmic dynein subunit families. (PubMed id 16440056)1, 2 Pfister K.K.... Fisher E.M.C. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method. (PubMed id 12056414)1, 2 Ohara O.... Koseki H. (2002)
- Chromosomal localization of the human cytoplasmic dynein heavy chain gene DNCH2 to 11q21-->q22.1. (PubMed id 9763680)1, 3 Koehler M.R.... Neesen J. (1998)
- Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles. (PubMed id 8666668)1, 2 Vaisberg E.A.... McIntosh J.R. (1996)
- Phylogeny and expression of axonemal and cytoplasmic dynein genes in sea urchins. (PubMed id 8186465)1, 2 Gibbons B.H.... Gibbons I.R. (1994)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
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External Searches for DYNC2H1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
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Genome Databases showing DYNC2H1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DYNC2H1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing DYNC2H1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for DYNC2H1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DYNC2H1 gene: Search GeneIP for patents involving DYNC2H1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for DYNC2H1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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 | |
 | |
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for DYNC2H1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DYNC2H1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DYNC2H1 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for DYNC2H1 | | Browse OriGene untagged cDNA clones in CMV expression vector | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DYNC2H1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DYNC2H1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DYNC2H1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DYNC2H1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DYNC2H1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DYNC2H1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DYNC2H1 |
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 | | DYNC2H1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DYNC2H1 |
|  |  |  | | | Search ThermoFisher Antibodies for DYNC2H1 |
| | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DYNC2H1 |
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