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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DYNC1LI2 Gene

protein-coding   GIFtS: 57
GCID: GC16M066754

Dynein, Cytoplasmic 1, Light Intermediate Chain 2

(Previous names: dynein, cytoplasmic, light intermediate polypeptide 2)
(Previous symbol: DNCLI2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Dynein, Cytoplasmic 1, Light Intermediate Chain 21 2     LIC-22 3
DNCLI21 2 3     LIC22 3
Dynein, Cytoplasmic, Light Intermediate Polypeptide 21 2     LIC53/552 3
Dynein Light Intermediate Chain 2, Cytosolic2 3     Cytoplasmic Dynein 1 Light Intermediate Chain 22

External Ids:    HGNC: 29661   Entrez Gene: 17832   Ensembl: ENSG000001357207   OMIM: 6114065   UniProtKB: O432373   

Export aliases for DYNC1LI2 gene to outside databases

Previous GC identifers: GC16M065314 GC16M052629


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DYNC1LI2 Gene:
Cytoplasmic dynein is a microtubule-associated motor protein (Hughes et al., 1995 (PubMed 7738094)). See DYNC1H1
(MIM 600112) for general information about dyneins.(supplied by OMIM, Mar 2008)

GeneCards Summary for DYNC1LI2 Gene: 
DYNC1LI2 (dynein, cytoplasmic 1, light intermediate chain 2) is a protein-coding gene. Diseases associated with DYNC1LI2 include north american indian childhood cirrhosis, and paraplegia, and among its related super-pathways are Immune System and Cell cycle Spindle assembly and chromosome separation. GO annotations related to this gene include motor activity and ATP binding. An important paralog of this gene is DYNC1LI1.

UniProtKB/Swiss-Prot: DC1L2_HUMAN, O43237
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are
thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.
Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along
microtubules. May play a role in binding dynein to membranous organelles or chromosomes

Gene Wiki entry for DYNC1LI2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010498.15  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DYNC1LI2 gene promoter:
         CUTL1   NF-AT   NF-AT4   NF-AT2   HSF2   AP-2beta   NF-AT3   AP-2alpha   NF-AT1   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDYNC1LI2 promoter sequence
   Search SABiosciences Chromatin IP Primers for DYNC1LI2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DYNC1LI2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.1   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22.1

DYNC1LI2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DYNC1LI2 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M066754:  view genomic region     (about GC identifiers)

Start:
66,754,796 bp from pter      End:
66,785,701 bp from pter
Size:
30,906 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DC1L2_HUMAN, O43237 (See protein sequence)
Recommended Name: Cytoplasmic dynein 1 light intermediate chain 2  
Size: 492 amino acids; 54099 Da
Subunit: Homodimer (By similarity). The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs)
and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs)
and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy
chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic
subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. Self-associates.
Interacts with DYNC1H1; DYNC1LI1 and DYNC1LI2 bind mutually exclusive to DYNC1H1 (By similarity)
Subcellular location: Cytoplasm, cytoskeleton (By similarity)
Secondary accessions: A8K6V1 Q8TAT3

Explore the universe of human proteins at neXtProt for DYNC1LI2: NX_O43237

Explore proteomics data for DYNC1LI2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O43237

  • DYNC1LI2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DYNC1LI2 Protein Expression
    REFSEQ proteins: NP_006132.1  
    ENSEMBL proteins: 
     ENSP00000258198   ENSP00000394289   ENSP00000462434   ENSP00000462017   ENSP00000462224  
     ENSP00000408566   ENSP00000457707   ENSP00000457464   ENSP00000463124   ENSP00000368795  
    Reactome Protein details: O43237
    Human Recombinant Protein Products for DYNC1LI2: 
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    Cloud-Clone Corp. Proteins for DYNC1LI2 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005813centrosome IDA--
    GO:0005829cytosol TAS--
    GO:0005868cytoplasmic dynein complex IEA--
    GO:0005874microtubule IEA--

    DYNC1LI2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    DYN: Cytoplasmic dyneins

    3 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR022780 Dynein_light_int_chain
     IPR008467 Dynein1_light_intermed_chain

    Graphical View of Domain Structure for InterPro Entry O43237

    ProtoNet protein and cluster: O43237

    1 Blocks protein domain: IPB008467 Dynein light intermediate chain

    UniProtKB/Swiss-Prot: DC1L2_HUMAN, O43237
    Similarity: Belongs to the dynein light intermediate chain family


    DYNC1LI2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DC1L2_HUMAN, O43237
    Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are
    thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.
    Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along
    microtubules. May play a role in binding dynein to membranous organelles or chromosomes

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003774motor activity ----
    GO:0003777microtubule motor activity IEA--
    GO:0005515protein binding ----
    GO:0005524ATP binding IEA--
         
    DYNC1LI2 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for DYNC1LI2:
     Decreased number of cells in m  Increased S DNA content  Increased number of mitotic ce 

    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidDYNC1LI2 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DYNC1LI2 About   (see all 8)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Immune System
    Immune System0.56
    Adaptive Immune System0.56
    2Cell cycle Spindle assembly and chromosome separation
    Cell cycle Spindle assembly and chromosome separation0.94
    3Regulation of degradation of wt-CFTR
    Regulation of degradation of deltaF508 CFTR in CF0.59
    4Cytoskeleton remodeling Neurofilaments
    Cytoplasmic microtubules0.32
    5MHC class II antigen presentation
    MHC class II antigen presentation0.32

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 EMD Millipore Pathways for DYNC1LI2
        Cell cycle Spindle assembly and chromosome separation
    Cytoplasmic microtubules


    2 GeneGo (Thomson Reuters) Pathways for DYNC1LI2
        Cell cycle Spindle assembly and chromosome separation
    Regulation of degradation of deltaF508 CFTR in CF

    3        Reactome Pathways for DYNC1LI2
        Adaptive Immune System
    Immune System
    MHC class II antigen presentation


    3         Kegg Pathways  (Kegg details for DYNC1LI2):
        Phagosome
    Vasopressin-regulated water reabsorption
    Salmonella infection


    DYNC1LI2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DYNC1LI2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/833 Interacting proteins for DYNC1LI2 (O432372, 3 ENSP000002581984) via UniProtKB, MINT, STRING, and/or I2D (see all 833)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DYNC1H1Q142042, 3, ENSP000003489654MINT-7945693 MINT-7947479 I2D: score=1 STRING: ENSP00000348965
    CDC5LQ994592, ENSP000003605324MINT-7945693 MINT-7947479 STRING: ENSP00000360532
    DCTN2Q135612, ENSP000004089104MINT-7945693 MINT-7947479 STRING: ENSP00000408910
    ELAVL1Q157172, ENSP000003852694MINT-7945693 MINT-7947479 STRING: ENSP00000385269
    SNW1Q135732, ENSP000002615314MINT-7945693 MINT-7947479 STRING: ENSP00000261531
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000226microtubule cytoskeleton organization IEA--
    GO:0006810transport IEA--
    GO:0007018microtubule-based movement IEA--
    GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II TAS--
    GO:0051642centrosome localization IEA--

    DYNC1LI2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DYNC1LI2 (DC1L2)

    Search CenterWatch for drugs/clinical trials and news about DYNC1LI2 / DC1L2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DYNC1LI2 gene: 
    NM_006141.2  

    Unigene Cluster for DYNC1LI2:

    Dynein, cytoplasmic 1, light intermediate chain 2
    Hs.369068  [show with all ESTs]
    Unigene Representative Sequence: NM_006141
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000258198(uc002eqb.1 uc010vis.1) ENST00000443351 ENST00000563628
    ENST00000569320 ENST00000564559 ENST00000567499 ENST00000568453 ENST00000564833
    ENST00000565532 ENST00000570201 ENST00000440564(uc010vit.2 uc010viu.2)
    ENST00000561727 ENST00000566150 ENST00000568180 ENST00000564090 ENST00000379482

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    Additional mRNA sequence: 

    AF035812.1 AK024863.1 AK095237.1 AK291766.1 AK295049.1 AK303031.1 AK304233.1 AL834400.1 
    BC010928.1 BC022934.1 BC025959.1 BC036633.2 BC069056.1 BX648863.1 

    16 DOTS entries:

    DT.100827470  DT.91675447  DT.100827468  DT.75178535  DT.120663657  DT.95168980  DT.86839936  DT.97833330 
    DT.100827471  DT.99929717  DT.100037991  DT.120663720  DT.91956853  DT.95168979  DT.99985049  DT.120663619 

    24/664 AceView cDNA sequences (see all 664):

    CA412766 BM795175 AA010580 BE855558 AW014727 AA983979 CD677630 AA634200 
    AI418709 AA991655 F10064 BM982268 AA759161 AI358032 AI139934 AL701847 
    BM847909 AI752932 BM464427 BM702738 AW516832 BM720737 N93514 CF130687 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for DYNC1LI2 (see all 8)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13
    SP1:        -                                                                 -     -     -           -                                             
    SP2:                                                                                                                                                
    SP3:                                                                                                  -                                             
    SP4:        -                       -                                                                                                               
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for DYNC1LI2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DYNC1LI2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGAACCTTG
    DYNC1LI2 Expression
    About this image


    See DYNC1LI2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DYNC1LI2

    SOURCE GeneReport for Unigene cluster: Hs.369068
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for DYNC1LI2 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dync1li21 , 5 dynein, cytoplasmic 1 light intermediate chain 21, 5 90.45(n)1
    96.95(a)1
      8 (53.04 cM)5
    2346631  NM_001013380.21  NP_001013398.21 
     1044176745 
    chicken
    (Gallus gallus)
    Aves DYNC1LI21 dynein, cytoplasmic 1, light intermediate chain 2 81.31(n)
    89.53(a)
      415793  NM_001030573.1  NP_001025744.1 
    lizard
    (Anolis carolinensis)
    Reptilia DYNC1LI26
    Uncharacterized protein
    80(a)
    1 ↔ 1
    GL343295.1(139651-169738)
    zebrafish
    (Danio rerio)
    Actinopterygii dync1li21 dynein, cytoplasmic 1, light intermediate chain 2 71.21(n)
    77.48(a)
      573266  NM_001017669.1  NP_001017669.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Dlic1 Dynein light intermediate chain 51.52(n)
    47.23(a)
      32057  NM_132466.2  NP_572694.1 
    worm
    (Caenorhabditis elegans)
    Secernentea dli-11 Protein DLI-1 46.75(n)
    35.44(a)
      178260  NM_070117.6  NP_502518.2 


    ENSEMBL Gene Tree for DYNC1LI2 (if available)
    TreeFam Gene Tree for DYNC1LI2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DYNC1LI2 gene
    DYNC1LI12  
    3 SIMAP similar genes for DYNC1LI2 using alignment to 10 protein entries:     DC1L2_HUMAN (see all proteins):
    DKFZp686J08252    DKFZp686A1525    DYNC1LI1

    DYNC1LI2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/645 SNPs in DYNC1LI2 are shown (see all 645)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1180862321,2
    F--66754398(+) AGATAT/CATAAA 1 -- ds50011Minor allele frequency- C:0.03NA 120
    rs1912725121,2
    --66754501(+) AAAAAC/TCAAAA 1 -- ds50010--------
    rs1839985471,2
    --66754504(+) AACCAA/GAAAAA 1 -- ds50010--------
    rs793332951,2
    C,F--66754576(+) AACCAC/GTGGAG 1 -- ds50013Minor allele frequency- G:0.07CSA WA 120
    rs1868662321,2
    --66754774(+) ATTCAC/TCATAA 1 -- ds50010--------
    rs1486715311,2
    C--66754814(+) GGATTC/TGTGTT 1 -- ut310--------
    rs115536821,2
    C--66754853(+) TTTTTC/TCCAGG 1 -- ut31 trp31Minor allele frequency- T:0.00NA 2
    rs1421053861,2
    --66755022(+) ACATTC/GTTAAG 1 -- ut310--------
    rs1921535101,2
    --66755027(+) GTTAAA/GGTCAT 1 -- ut310--------
    rs1511796971,2
    C--66755028(+) TTAAGA/GTCATG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DYNC1LI2 (66754796 - 66785701 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DYNC1LI2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv906786CNV Loss21882294
    dgv2885n71CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611406    OMIM disorders: --

    2 diseases for DYNC1LI2:    About MalaCards
    north american indian childhood cirrhosis    paraplegia


    DYNC1LI2 for disorders           About GeneDecksing


    Export disorders for DYNC1LI2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DYNC1LI2 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with DYNC1LI2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    3. Cytoplasmic dynein nomenclature. (PubMed id 16260502)1, 3 Pfister K.K....Vallee R.B. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    8. Recruitment of dynein to late endosomes and lysosomes through light intermediate chains. (PubMed id 21169557)1 Tan S.C....Vallee R.B. (2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1783 HGNC: 2966 AceView: DNCLI2 Ensembl:ENSG00000135720 euGenes: HUgn1783
    ECgene: DYNC1LI2 Kegg: 1783 H-InvDB: DYNC1LI2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DYNC1LI2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DYNC1LI2 gene:
    Search GeneIP for patents involving DYNC1LI2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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