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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DYNC1LI1 Gene

protein-coding   GIFtS: 53
GCID: GC03M032543

dynein, cytoplasmic 1, light intermediate chain 1

(Previous names: dynein, cytoplasmic, light intermediate polypeptide 1 )
(Previous symbol: DNCLI1)
 Explore 1 disease affiliated with
DYNC1LI1 via our new
 Human Malady Compendium 
Biological research products
for DYNC1LI1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Dynein, Cytoplasmic 1, Light Intermediate Chain 11 2     DLC-A2 3
DNCLI11 2 3     LIC12 3
Dynein, Cytoplasmic, Light Intermediate Polypeptide 11 2     Cytoplasmic Dynein 1 Light Intermediate Chain 12
Dynein Light Chain A2 3     Dynein Light Chain-A2
Dynein Light Intermediate Chain 1, Cytosolic2 3     

External Ids:    HGNC: 187451   Entrez Gene: 511432   Ensembl: ENSG000001446357   UniProtKB: Q9Y6G93   

Export aliases for DYNC1LI1 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: DC1L1_HUMAN, Q9Y6G9
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are
thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic
dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May
play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent
transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form
appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores

Gene Wiki entry for DYNC1LI1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DYNC1LI1 gene promoter:
         Pax-5   SREBP-1c   SREBP-1b   RORalpha2   RORalpha1   POU2F1   SREBP-1a   POU2F1a   HOXA5   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDYNC1LI1 promoter sequence
   Search SABiosciences Chromatin IP Primers for DYNC1LI1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DYNC1LI1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p22.3   Ensembl cytogenetic band:  3p22.3   HGNC cytogenetic band: 3p23

DYNC1LI1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DYNC1LI1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M032543:  view genomic region     (about GC identifiers)

Start:
32,567,463 bp from pter      End:
32,612,366 bp from pter
Size:
44,904 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DC1L1_HUMAN, Q9Y6G9 (See protein sequence)
Recommended Name: Cytoplasmic dynein 1 light intermediate chain 1  
Size: 523 amino acids; 56579 Da
Subunit: Homodimer (By similarity). The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a
number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light
chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer
serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs
bind directly to the HC dimer and the LCs assemble on the IC dimer. Self-associates. Interacts with DYNC1H1; DYNC1LI1
and DYNC1LI2 bind mutually exclusive to DYNC1H1. Interacts with PCNT (By similarity). Interacts with human adenovirus
5 hexon protein; this interaction probably allows virus intracellular transport
Subcellular location: Cytoplasm (By similarity). Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle
pole
Secondary accessions: A2RRG7 Q53HC8 Q53HK7

Explore the universe of human proteins at neXtProt for DYNC1LI1: NX_Q9Y6G9

Post-translational modifications:

  • Phosphorylated during mitosis but not in interphase1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y6G9

  • DYNC1LI1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_057225.2  
    ENSEMBL proteins: 
     ENSP00000273130   ENSP00000407279   ENSP00000390507   ENSP00000409019  

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    Uscn Proteins for DYNC1LI1

    Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000776kinetochore IDA19229290
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0000922spindle pole IDA19229290
    GO:0005737cytoplasm IDA--
    GO:0005813centrosome IDA--


    DYNC1LI1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DYNC1LI1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR022780 Dynein_light_int_chain
     IPR008467 Dynein1_light_intermed_chain

    Graphical View of Domain Structure for InterPro Entry Q9Y6G9

    ProtoNet protein and cluster: Q9Y6G9

    1 Blocks protein family: IPB008467 Dynein light intermediate chain

    UniProtKB/Swiss-Prot: DC1L1_HUMAN, Q9Y6G9
    Similarity: Belongs to the dynein light intermediate chain family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: DC1L1_HUMAN, Q9Y6G9
    Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are
    thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic
    dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May
    play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent
    transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form
    appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores

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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003774motor activity IEA--
    GO:0005524ATP binding IEA--


    DYNC1LI1 for ontologies           About GeneDecksing


    Animal Models:
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Dync1li1):
     behavior/neurological  cellular  digestive/alimentary  nervous system 

    DYNC1LI1 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell cycle_Spindle assembly and chromosome separation
    Cell cycle_Spindle assembly and chromosome separation1.00
    Cell cycle Spindle assembly and chromosome separation0.94
    2Vasopressin-regulated water reabsorption
    Vasopressin-regulated water reabsorption1.00
    3Phagosome
    Phagosome1.00
    4Regulation of degradation of wt-CFTR
    Regulation of degradation of deltaF508 CFTR in CF0.59
    5Cytoskeleton remodeling Neurofilaments
    Cytoplasmic microtubules0.32

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    2 EMD Millipore Pathways for DYNC1LI1
        Cell cycle Spindle assembly and chromosome separation
    Cytoplasmic microtubules


    2 GeneGo (Thomson Reuters) Pathways for DYNC1LI1
        Cell cycle Spindle assembly and chromosome separation
    Regulation of degradation of deltaF508 CFTR in CF


    2         Kegg Pathways  (Kegg details for DYNC1LI1):
        Phagosome
    Vasopressin-regulated water reabsorption


    DYNC1LI1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DYNC1LI1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/584 Interacting proteins for DYNC1LI1 (Q9Y6G92, 3 ENSP000002731304) via UniProtKB, MINT, STRING, and/or I2D (see all 584)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PCNTO956132, 3, ENSP000003525724MINT-7947479 I2D: score=1 STRING: ENSP00000352572
    MAD2L1Q132572, 3, ENSP000002965094MINT-7264691 I2D: score=1 STRING: ENSP00000296509
    DYNC1H1Q142042, ENSP000003489654MINT-7947479 STRING: ENSP00000348965
    NUP85Q9BW273, ENSP000002455444I2D: score=1 STRING: ENSP00000245544
    RAB4AP203383, ENSP000003556514I2D: score=2 STRING: ENSP00000355651
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport IEA--
    GO:0007067mitosis IEA--
    GO:0019048virus-host interaction IEA--
    GO:0044419interspecies interaction between organisms ----
    GO:0046605regulation of centrosome cycle ----


    DYNC1LI1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DYNC1LI1
    Search CenterWatch for drugs/clinical trials and news about DYNC1LI1 / DC1L1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DYNC1LI1 gene: 
    NM_016141.3  

    Unigene Cluster for DYNC1LI1:

    Dynein, cytoplasmic 1, light intermediate chain 1
    Hs.529495  [show with all ESTs]
    Unigene Representative Sequence: NM_016141
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000273130(uc003cfb.4 uc011axh.2) ENST00000481915 ENST00000432458
    ENST00000472985 ENST00000413350 ENST00000424991 ENST00000475193 ENST00000474077


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    hsa-miR-3678-3p hsa-miR-582-5p hsa-miR-3920 hsa-miR-3919 hsa-miR-1252
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    Inhib. RNA
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    Additional cDNA sequence: 

    AF078849.1 AK001081.1 AK074348.1 AK222573.1 AK222653.1 AK293253.1 BC131620.1 

    9 DOTS entries:

    DT.447414  DT.100814567  DT.92437869  DT.99931463  DT.100814580  DT.120867585  DT.120867590  DT.120867595 
    DT.95166642 

    24/245 AceView cDNA sequences (see all 245):

    BM930439 AL554561 CA446301 CR595277 CA449447 AV646465 CK299839 CR619992 
    BU623635 BM997517 BM474013 AK074348 BE856990 CA443361 AA149455 D20244 
    BU743129 AI004922 BM478520 AW518200 AA600137 AK001081 AI381316 CA438680 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for DYNC1LI1 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15
    SP1:                                -     -                 -                                                                     
    SP2:                                -     -     -     -     -                                                                     
    SP3:                                -                                                                                             
    SP4:                                      -                 -                                                                     
    SP5:                                -     -                                                                                       


    ECgene alternative splicing isoforms for DYNC1LI1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DYNC1LI1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAGAACTAGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See DYNC1LI1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DYNC1LI1

    SOURCE GeneReport for Unigene cluster: Hs.529495
        SABiosciences Custom PCR Arrays for DYNC1LI1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DYNC1LI1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for DYNC1LI1 gene from 7/23 species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dync1li11 , 5 dynein cytoplasmic 1 light intermediate chain 11, 5 87.04(n)1
    94.83(a)1
      9 (64.96 cM)5
    2356611  NM_146229.21  NP_666341.11 
     1146888315 
    chicken
    (Gallus gallus)
    Aves DYNC1LI11 dynein, cytoplasmic 1, light intermediate chain 1 82.07(n)
    88.3(a)
      420668  NM_001167737.1  NP_001161209.1 
    lizard
    (Anolis carolinensis)
    Reptilia DYNC1LI16
    --
    82(a)
    1 ↔ 1
    1(193476359-193508172)
    African clawed frog
    (Xenopus laevis)
    Amphibia dnclic1-prov2 cytoplasmic dynein light-intermediate chain 80(n)    BC045030.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc73a072 Transcribed sequence with weak similarity to protein more 71.1(n)    CA496732.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Dlic6
    Dynein light intermediate chain
    43(a)
    1 → many
    X(11048434-11057245)
    worm
    (Caenorhabditis elegans)
    Secernentea dli-16
    Dynein Light Intermediate chain family member (dli...
    30(a)
    1 → many
    IV(13096959-13098789)


    ENSEMBL Gene Tree for DYNC1LI1 (if available)
    TreeFam Gene Tree for DYNC1LI1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DYNC1LI1 gene
    DYNC1LI22  
    18/20 SIMAP similar genes for DYNC1LI1 using alignment to 4 protein entries:     DC1L1_HUMAN (see all proteins) (see all similar genes):
    FLJ00047    COQ5    KIAA1651    DKFZp686A1525    KIAA0101    PFKFB3
    DKFZp686J08252    C12orf76    SNRPF    GALK2    TUBA1C    pp12301
    SEC14L3    SH2B3    DYNC1LI2    ERMN    ATF1    NCKAP1L

    DYNC1LI1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for DYNC1LI1
    PGOHUM00000235176


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/827 NCBI SNPs in DYNC1LI1 are shown (see all 827    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs738265781,2
    C,--32567075(+) TCGAAA/CATTTT 1 -- int13Minor allele frequency- C:0.15WA CSA 121
    rs764382851,2
    F,--32567161(+) AAAAAG/ATTGCA 1 -- int11Minor allele frequency- A:0.03WA 118
    rs2014912551,2
    --32567206(+) AACAA-/TACAG 
            
    TATAA
    1 -- int10--------
    rs1859662651,2
    --32567208(+) CAATAC/TAGTAT 1 -- int10--------
    rs603231071,2
    --32567282(+) AGGAGG/AATGTG 1 -- int13Minor allele frequency- A:0.15CSA WA EA 240
    rs1898347211,2
    --32567381(+) CCTCAC/TGGATA 1 -- int10--------
    rs677584581,2
    C,--32567555(+) AAGCC-/ATATATA 1 -- ut310--------
    rs1163639831,2
    F,--32567571(+) TATATA/GTGTAT 1 -- ut311Minor allele frequency- G:0.07WA 118
    rs1156781031,2
    F,--32567727(+) CAGGAT/ACAGTG 1 -- ut311Minor allele frequency- A:0.05WA 118
    rs771473321,2
    --32567762(+) AACGCT/CATCTG 1 -- ut311Minor allele frequency- C:0.01NA 120

    HapMap Linkage Disequilibrium report for DYNC1LI1 (32567463 - 32612366 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for DYNC1LI1: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DYNC1LI1 for disorders           About GeneDecksing

    1 disease for DYNC1LI1:    About MalaCards
    malaria


    Export disorders for DYNC1LI1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DYNC1LI1 gene, integrated from 9 sources (see all 37):
    (articles sorted by number of sources associating them with DYNC1LI1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint. (PubMed id 19229290)1, 2 Sivaram M.V....Doxsey S.J. (2009)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    3. Cytoplasmic dynein nomenclature. (PubMed id 16260502)1, 3 Pfister K.K....Vallee R.B. (2005)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    5. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    6. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
    7. Recruitment of dynein to late endosomes and lysosomes through light intermediate chains. (PubMed id 21169557)1 Tan S.C....Vallee R.B. (2011)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)1 Emanuele M.J....Elledge S.J. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51143 HGNC: 18745 AceView: DNCLI1 Ensembl:ENSG00000144635 euGenes: HUgn51143
    ECgene: DYNC1LI1 Kegg: 51143 H-InvDB: DYNC1LI1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DYNC1LI1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DYNC1LI1 gene:
    Search GeneIP for patents involving DYNC1LI1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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