Free for academic non-profit institutions. Other users need a Commercial license

Aliases for DUXB Gene

Aliases for DUXB Gene

  • Double Homeobox B 2 3 5

External Ids for DUXB Gene

Previous GeneCards Identifiers for DUXB Gene

  • GC16U900669

Summaries for DUXB Gene

GeneCards Summary for DUXB Gene

DUXB (Double Homeobox B) is a Protein Coding gene. An important paralog of this gene is DUX4.

Additional gene information for DUXB Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DUXB Gene

Genomics for DUXB Gene

Genomic Location for DUXB Gene

Chromosome:
16
Start:
75,693,729 bp from pter
End:
75,701,459 bp from pter
Size:
7,731 bases
Orientation:
Minus strand

Genomic View for DUXB Gene

Genes around DUXB on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DUXB Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DUXB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for Regulatory Elements and RefSeq DNA sequence for DUXB Gene

Proteins for DUXB Gene

  • Protein details for DUXB Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A1W2PPF3
    Recommended name:
    Double homeobox B
    Protein Accession:
    A0A1W2PPF3

    Protein attributes for DUXB Gene

    Size:
    345 amino acids
    Molecular mass:
    40370 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DUXB Gene

Post-translational modifications for DUXB Gene

No Post-translational modifications

Other Protein References for DUXB Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for DUXB Gene

Domains & Families for DUXB Gene

Gene Families for DUXB Gene

Protein Domains for DUXB Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DUXB: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for DUXB Gene

Function for DUXB Gene

Gene Ontology (GO) - Molecular Function for DUXB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043565 sequence-specific DNA binding IEA --
genes like me logo Genes that share ontologies with DUXB: view

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for DUXB
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DUXB Gene

Localization for DUXB Gene

Gene Ontology (GO) - Cellular Components for DUXB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with DUXB: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for DUXB Gene

Pathways & Interactions for DUXB Gene

No Data Available

Interacting Proteins for DUXB Gene

Gene Ontology (GO) - Biological Process for DUXB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with DUXB: view

No data available for Pathways by source and SIGNOR curated interactions for DUXB Gene

Drugs & Compounds for DUXB Gene

No Compound Related Data Available

Transcripts for DUXB Gene

mRNA/cDNA for DUXB Gene

(3) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for DUXB
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for DUXB Gene

No ASD Table

Relevant External Links for DUXB Gene

GeneLoc Exon Structure for
DUXB
ECgene alternative splicing isoforms for
DUXB

Expression for DUXB Gene

NURSA nuclear receptor signaling pathways regulating expression of DUXB Gene:

DUXB
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DUXB Gene

Orthologs for DUXB Gene

Evolution for DUXB Gene

ENSEMBL:
Gene Tree for DUXB (if available)
TreeFam:
Gene Tree for DUXB (if available)

No data available for Orthologs for DUXB Gene

Paralogs for DUXB Gene

Paralogs for DUXB Gene

genes like me logo Genes that share paralogs with DUXB: view

Variants for DUXB Gene

Relevant External Links for DUXB Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DUXB

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for DUXB Gene

Disorders for DUXB Gene

Relevant External Links for DUXB

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DUXB

No disorders were found for DUXB Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DUXB Gene

Publications for DUXB Gene

  1. Annotation, nomenclature and evolution of four novel homeobox genes expressed in the human germ line. (PMID: 17005330) Booth HA … Holland PW (Gene 2007) 2 3 60
  2. Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy. (PMID: 17668377) Clapp J … Hewitt JE (American journal of human genetics 2007) 2 3 60
  3. Characterization and target genes of nine human PRD-like homeobox domain genes expressed exclusively in early embryos. (PMID: 27412763) Madissoon E … Kere J (Scientific reports 2016) 3 60
  4. Novel PRD-like homeodomain transcription factors and retrotransposon elements in early human development. (PMID: 26360614) Töhönen V … Kere J (Nature communications 2015) 3 60

Products for DUXB Gene

Sources for DUXB Gene

Content
Loading form....