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Aliases for DUX5 Gene

Aliases for DUX5 Gene

  • Double Homeobox 5 2 3
  • Double Homeobox Protein 1 3
  • Double Homeobox Protein 5 3
  • Double Homeobox, 5 3
  • DUX1 3

External Ids for DUX5 Gene

Summaries for DUX5 Gene

Entrez Gene Summary for DUX5 Gene

  • The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX5, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008]

GeneCards Summary for DUX5 Gene

DUX5 (Double Homeobox 5) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and transcription regulatory region sequence-specific DNA binding.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DUX5 Gene

Genomics for DUX5 Gene

Genomic Location for DUX5 Gene

Orientation:
Unknown strand

Genomic View for DUX5 Gene

Cytogenetic band:

No data available for RefSeq DNA sequence and Regulatory Elements for DUX5 Gene

Proteins for DUX5 Gene

  • Protein details for DUX5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96PT3-DUX5_HUMAN
    Recommended name:
    Double homeobox protein 5
    Protein Accession:
    Q96PT3
    Secondary Accessions:

    Protein attributes for DUX5 Gene

    Size:
    197 amino acids
    Molecular mass:
    22164 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes. May be functional despite lack of introns and a poly(A) addition signal

    Alternative splice isoforms for DUX5 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DUX5 Gene

Proteomics data for DUX5 Gene at MOPED

Post-translational modifications for DUX5 Gene

No Post-translational modifications

Other Protein References for DUX5 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for DUX5 Gene

Domains for DUX5 Gene

UniProtKB/Swiss-Prot:

DUX5_HUMAN
Domain:
  • Contains 2 homeobox DNA-binding domains.:
    • Q96PT3
Family:
  • Belongs to the paired homeobox family.:
    • Q96PT3
genes like me logo Genes that share domains with DUX5: view

No data available for Gene Families for DUX5 Gene

Function for DUX5 Gene

Gene Ontology (GO) - Molecular Function for DUX5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043565 sequence-specific DNA binding IEA --
genes like me logo Genes that share ontologies with DUX5: view

Phenotypes for DUX5 Gene

genes like me logo Genes that share phenotypes with DUX5: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for DUX5 Gene

Localization for DUX5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DUX5 Gene

Gene Ontology (GO) - Cellular Components for DUX5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with DUX5: view

Pathways for DUX5 Gene

SuperPathways for DUX5 Gene

No Data Available

Interacting Proteins for DUX5 Gene

Gene Ontology (GO) - Biological Process for DUX5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with DUX5: view

No data available for Pathways by source for DUX5 Gene

Transcripts for DUX5 Gene

mRNA/cDNA for DUX5 Gene

(1) REFSEQ mRNAs :

Alternative Splicing Database (ASD) splice patterns (SP) for DUX5 Gene

No ASD Table

Relevant External Links for DUX5 Gene

ECgene alternative splicing isoforms for
DUX5

Expression for DUX5 Gene

mRNA expression in normal human tissues for DUX5 Gene

mRNA Expression by UniProt/SwissProt for DUX5 Gene

Q96PT3-DUX5_HUMAN
Tissue specificity: Expressed in hepatoma Hep3B cells.
genes like me logo Genes that share expressions with DUX5: view

Orthologs for DUX5 Gene

No data available for Orthologs and Evolution for DUX5 Gene

Paralogs for DUX5 Gene

Selected SIMAP similar genes for DUX5 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with DUX5: view

No data available for Paralogs for DUX5 Gene

Variants for DUX5 Gene

Sequence variations from dbSNP and Humsavar for DUX5 Gene

SNP ID Clin Chr 00 pos Sequence Context AA Info Type MAF
VAR_059347 -
VAR_059348 -
VAR_059349 -
VAR_059350 -, -

No data available for Structural Variations from Database of Genomic Variants (DGV) for DUX5 Gene

Disorders for DUX5 Gene

No disorders were found for DUX5 Gene.

No data available for UniProtKB/Swiss-Prot for DUX5 Gene

Publications for DUX5 Gene

  1. Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements. (PMID: 11245978) Beckers M.-C. … Belayew A. (Gene 2001) 2 3 4
  2. Intracellular trafficking and dynamics of double homeodomain proteins. (PMID: 15709750) Oestlund C. … Worman H.J. (Biochemistry 2005) 3
  3. Characterization of a double homeodomain protein (DUX1) encoded by a cDNA homologous to 3.3-kb dispersed repeated elements. (PMID: 9736770) Ding H. … Belayew A. (Hum. Mol. Genet. 1998) 3

Products for DUX5 Gene

Sources for DUX5 Gene

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