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Aliases for DUX3 Gene

Aliases for DUX3 Gene

  • Double Homeobox 3 2 3

External Ids for DUX3 Gene

Previous GeneCards Identifiers for DUX3 Gene

  • GC04P191693
  • GC04P191694
  • GC04M191320

Summaries for DUX3 Gene

Entrez Gene Summary for DUX3 Gene

  • The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX3, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008]

GeneCards Summary for DUX3 Gene

DUX3 (Double Homeobox 3) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and transcription regulatory region sequence-specific DNA binding.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DUX3 Gene

Genomics for DUX3 Gene

Genomic Location for DUX3 Gene

Orientation:
Unknown strand

Genomic View for DUX3 Gene

Cytogenetic band:

No data available for Regulatory Elements and RefSeq DNA sequence for DUX3 Gene

Proteins for DUX3 Gene

  • Protein details for DUX3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96PT4-DUX3_HUMAN
    Recommended name:
    Putative double homeobox protein 3
    Protein Accession:
    Q96PT4
    Secondary Accessions:
    • Q9UND2

    Protein attributes for DUX3 Gene

    Size:
    197 amino acids
    Molecular mass:
    22130 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes. May be functional despite lack of introns and of a poly(A) addition signal

    Alternative splice isoforms for DUX3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DUX3 Gene

Proteomics data for DUX3 Gene at MOPED

Post-translational modifications for DUX3 Gene

No Post-translational modifications

Other Protein References for DUX3 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for DUX3 Gene

Domains for DUX3 Gene

Protein Domains for DUX3 Gene

Suggested Antigen Peptide Sequences for DUX3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96PT4

UniProtKB/Swiss-Prot:

DUX3_HUMAN :
  • Q96PT4
Domain:
  • Contains 2 homeobox DNA-binding domains.
Family:
  • Belongs to the paired homeobox family.
genes like me logo Genes that share domains with DUX3: view

No data available for Gene Families for DUX3 Gene

Function for DUX3 Gene

Gene Ontology (GO) - Molecular Function for DUX3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
genes like me logo Genes that share ontologies with DUX3: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for DUX3 Gene

Localization for DUX3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DUX3 Gene

Gene Ontology (GO) - Cellular Components for DUX3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with DUX3: view

No data available for Subcellular locations from COMPARTMENTS for DUX3 Gene

Pathways for DUX3 Gene

SuperPathways for DUX3 Gene

No Data Available

Interacting Proteins for DUX3 Gene

Selected Interacting proteins: Q96PT4-DUX3_HUMAN for DUX3 Gene via MINT

Symbol External ID(s) Details
--

Gene Ontology (GO) - Biological Process for DUX3 Gene

None

No data available for Pathways by source for DUX3 Gene

Transcripts for DUX3 Gene

mRNA/cDNA for DUX3 Gene

(1) REFSEQ mRNAs :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for DUX3

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for DUX3
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for DUX3 Gene

No ASD Table

Relevant External Links for DUX3 Gene

ECgene alternative splicing isoforms for
DUX3

Expression for DUX3 Gene

mRNA expression in normal human tissues for DUX3 Gene

mRNA Expression by UniProt/SwissProt for DUX3 Gene

Q96PT4-DUX3_HUMAN
Tissue specificity: Expressed in hepatoma Hep3B cells.
genes like me logo Genes that share expressions with DUX3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Protein expression for DUX3 Gene

Orthologs for DUX3 Gene

No data available for Orthologs and Evolution for DUX3 Gene

Paralogs for DUX3 Gene

Selected SIMAP similar genes for DUX3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with DUX3: view

No data available for Paralogs for DUX3 Gene

Variants for DUX3 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for DUX3 Gene

Disorders for DUX3 Gene

No disorders were found for DUX3 Gene.

No data available for UniProtKB/Swiss-Prot for DUX3 Gene

Publications for DUX3 Gene

  1. Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements. (PMID: 11245978) Beckers M.-C. … Belayew A. (Gene 2001) 2 3 4
  2. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment. (PMID: 20467438) Arbuckle M.I. … Grant S.G. (EMBO Rep. 2010) 3

Products for DUX3 Gene

Sources for DUX3 Gene

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