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Aliases for DUX3 Gene

Aliases for DUX3 Gene

  • Double Homeobox 3 2 3

External Ids for DUX3 Gene

Previous GeneCards Identifiers for DUX3 Gene

  • GC04P191693
  • GC04P191694
  • GC04M191320

Summaries for DUX3 Gene

Entrez Gene Summary for DUX3 Gene

  • The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX3, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008]

GeneCards Summary for DUX3 Gene

DUX3 (Double Homeobox 3) is a Protein Coding gene.

Additional gene information for DUX3 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DUX3 Gene

Genomics for DUX3 Gene

Genomic Location for DUX3 Gene

No location information available

Genomic View for DUX3 Gene


Cytogenetic band:

No data available for Regulatory Elements and RefSeq DNA sequence for DUX3 Gene

Proteins for DUX3 Gene

  • Protein details for DUX3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96PT4-DUX3_HUMAN
    Recommended name:
    Putative double homeobox protein 3
    Protein Accession:
    Q96PT4
    Secondary Accessions:
    • Q9UND2

    Protein attributes for DUX3 Gene

    Size:
    197 amino acids
    Molecular mass:
    22130 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes. May be functional despite lack of introns and of a poly(A) addition signal.

    Alternative splice isoforms for DUX3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DUX3 Gene

Post-translational modifications for DUX3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DUX3 Gene

Domains & Families for DUX3 Gene

Suggested Antigen Peptide Sequences for DUX3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96PT4

UniProtKB/Swiss-Prot:

DUX3_HUMAN :
  • Belongs to the paired homeobox family.
Family:
  • Belongs to the paired homeobox family.
genes like me logo Genes that share domains with DUX3: view

No data available for Gene Families for DUX3 Gene

Function for DUX3 Gene

Gene Ontology (GO) - Molecular Function for DUX3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
genes like me logo Genes that share ontologies with DUX3: view
genes like me logo Genes that share phenotypes with DUX3: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for DUX3
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DUX3 Gene

Localization for DUX3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DUX3 Gene

Gene Ontology (GO) - Cellular Components for DUX3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with DUX3: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for DUX3 Gene

Pathways & Interactions for DUX3 Gene

No Data Available

Interacting Proteins for DUX3 Gene

Selected Interacting proteins: Q96PT4-DUX3_HUMAN for DUX3 Gene via IID

Symbol External ID(s) Details
LRRK2

Gene Ontology (GO) - Biological Process for DUX3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for DUX3 Gene

Drugs & Compounds for DUX3 Gene

No Compound Related Data Available

Transcripts for DUX3 Gene

mRNA/cDNA for DUX3 Gene

(1) REFSEQ mRNAs :

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for DUX3
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for DUX3 Gene

No ASD Table

Relevant External Links for DUX3 Gene

ECgene alternative splicing isoforms for
DUX3

Expression for DUX3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DUX3 Gene

NURSA nuclear receptor signaling pathways regulating expression of DUX3 Gene:

DUX3

mRNA Expression by UniProt/SwissProt for DUX3 Gene:

Q96PT4-DUX3_HUMAN
Tissue specificity: Expressed in hepatoma Hep3B cells.
genes like me logo Genes that share expression patterns with DUX3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DUX3 Gene

Orthologs for DUX3 Gene

No data available for Orthologs and Evolution for DUX3 Gene

Paralogs for DUX3 Gene

(12) SIMAP similar genes for DUX3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with DUX3: view

No data available for Paralogs for DUX3 Gene

Variants for DUX3 Gene

Relevant External Links for DUX3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DUX3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for DUX3 Gene

Disorders for DUX3 Gene

No disorders were found for DUX3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for DUX3 Gene

Publications for DUX3 Gene

  1. Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements. (PMID: 11245978) Beckers M … Belayew A (Gene 2001) 2 3 4 60

Products for DUX3 Gene

Sources for DUX3 Gene

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