The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX1, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008]
GeneCards Summary for DUX1 Gene
DUX1 (Double Homeobox 1) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and transcription regulatory region sequence-specific DNA binding.
UniProtKB/Swiss-Prot for DUX1 Gene
Probable transcription activator. Binds the P5 DNA element sequence 5-GATCTGAGTCTAATTGAGAATTACTGTAC-3.