Aliases for DUT Gene
Aliases for DUT Gene
External Ids for DUT Gene
- HGNC: 3078
- Entrez Gene: 1854
- Ensembl: ENSG00000128951
- OMIM: 601266
- UniProtKB: P33316
Previous GeneCards Identifiers for DUT Gene
- GC15P044181
- GC15P041669
- GC15P046202
- GC15P046339
- GC15P046410
- GC15P048623
- GC15P025461
Summaries for DUT Gene
-
This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19. [provided by RefSeq, Jul 2008]
GeneCards Summary for DUT Gene
DUT (Deoxyuridine Triphosphatase) is a Protein Coding gene. Diseases associated with DUT include Cysticercosis. Among its related pathways are Pyrimidine metabolism (KEGG) and Drug metabolism - cytochrome P450. Gene Ontology (GO) annotations related to this gene include magnesium ion binding.
UniProtKB/Swiss-Prot for DUT Gene
-
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DUT Gene
Genomics for DUT Gene
GeneHancer (GH) Regulatory Elements for DUT Gene
Regulatory Element Products
Genomic Locations for DUT Gene
- chr15:48,331,011-48,343,373
- (GRCh38/hg38)
- Size:
- 12,363 bases
- Orientation:
- Plus strand
- chr15:48,623,208-48,635,570
- (GRCh37/hg19)
Genomic View for DUT Gene
- Cytogenetic band:
-
- 15q21.1 by Ensembl
- 15q21.1 by Entrez Gene
- 15q21.1 by HGNC


RefSeq DNA sequence for DUT Gene
Proteins for DUT Gene
-
Protein details for DUT Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P33316-DUT_HUMAN
- Recommended name:
- Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial
- Protein Accession:
- P33316
- A8K650
- B4DPR5
- O14785
- Q16708
- Q16860
- Q6FHN1
- Q6NSA3
- Q96Q81
Protein attributes for DUT Gene
- Size:
- 252 amino acids
- Molecular mass:
- 26563 Da
- Cofactor:
- Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
- Quaternary structure:
-
- Homotrimer.
- Miscellaneous:
-
- Each trimer binds three substrate molecules. The ligands are bound between subunits, and for each substrate molecule, residues from adjacent subunits contribute to the binding interactions.
- SequenceCaution:
-
- Sequence=AAB71393.1; Type=Frameshift; Positions=29, 47; Evidence={ECO:0000305}; Sequence=AAB93866.1; Type=Frameshift; Positions=29, 47; Evidence={ECO:0000305}; Sequence=AAB94642.1; Type=Frameshift; Positions=29, 47; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for DUT Gene
Protein Expression for DUT Gene
Selected DME Specific Peptides for DUT Gene
- P33316:
-
- AAGYDLYSAYDYTIP
- GGFGSTG
- YGRVAPRSGLA
- GVIDEDYRGN
Post-translational modifications for DUT Gene
- Nuclear isoform 2 is phosphorylated in vivo on Ser-11, a reaction that can be catalyzed in vitro by CDC2. Phosphorylation in mature T-cells occurs in a cell cycle-dependent manner. Isoform 3 is not phosphorylated.
- Ubiquitination at Lys63 and posLast=9191
Other Protein References for DUT Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for DUT
- Novus Biologicals Antibodies for DUT
-
Abcam antibodies for DUT
- Invitrogen Antibodies for DUT
- GeneTex DUT antibody for DUT
-
Santa Cruz Biotechnology (SCBT) Antibodies for DUT
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for DUT
- Origene Custom Protein Services for DUT
- ProSpec Recombinant Proteins for DUT
- Search GeneTex for Proteins for DUT
-
ProSci Proteins for DUT
-
Abcam proteins for DUT
Assay Products
- antibodies-online: Search results for 5 available DUT Elisa Kits ranked by validation data
- Compare Top DUT Elisa Kits
-
Quality Products:
Domains & Families for DUT Gene
Gene Families for DUT Gene
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for DUT Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for DUT Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P33316- Family:
-
- Belongs to the dUTPase family.
Function for DUT Gene
Molecular function for DUT Gene
- GENATLAS Biochemistry:
- dUTP pyrophosphatase,involved in DNA replication
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: KM=2.5 uM for dUTP {ECO:0000269 PubMed:8631816}; Note=for both isoform 2 and isoform 3.;
- UniProtKB/Swiss-Prot CatalyticActivity:
- dUTP + H(2)O = dUMP + diphosphate.
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Phosphorylation is necessary for activity.
- UniProtKB/Swiss-Prot Function:
- This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Enzyme Numbers (IUBMB) for DUT Gene
Phenotypes From GWAS Catalog for DUT Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000287 | magnesium ion binding | IBA | -- |
GO:0003723 | RNA binding | IDA,HDA | 22658674 |
GO:0004170 | dUTP diphosphatase activity | IBA,IEA | -- |
GO:0005515 | protein binding | IPI | 16189514 |
GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for DUT Gene
- GenomeRNAi human phenotypes for DUT:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for DUT
-
-
ViGene Biosciences lentiviral particle packaged cDNA for DUT gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DUT gene
- Search ViGene Biosciences for DUT
CRISPR Products
-
OriGene CRISPR knockouts for DUT
- genomics-online: gRNA clones - Search results for available DUT gene related products
- Applied Biological Materials CRISPR for DUT
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for DUT
- GenScript: Design CRISPR guide RNA sequences for DUT
miRNA for DUT Gene
- miRTarBase miRNAs that target DUT
miRNA Products
- Search ViGene Biosciences for DUT
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for DUT
- Browse OriGene Inhibitory RNA Products For DUT
- genomics-online: shRNA clones - Search results for available DUT gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for DUT gene
Clone Products
-
OriGene ORF clones in human for DUT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for DUT
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for DUT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DUT
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available DUT gene related products
- orf clones - Search results for available DUT gene related products
- Applied Biological Materials Clones for DUT
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for DUT gene
-
ViGene Biosciences lentiviral particle packaged cDNA for DUT gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DUT gene
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for DUT Gene
Localization for DUT Gene
Subcellular locations from UniProtKB/Swiss-Prot for DUT Gene
- Isoform 2: Nucleus.
- Isoform 3: Mitochondrion.
- Nucleoplasm (3)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | TAS | 8631816 |
GO:0005654 | nucleoplasm | IDA,TAS | -- |
GO:0005737 | cytoplasm | IEA | -- |
GO:0005739 | mitochondrion | TAS,IEA | -- |
GO:0005829 | cytosol | IEA | -- |
Pathways & Interactions for DUT Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Metabolism |
.37
|
|
2 | Pyrimidine metabolism (REACTOME) | ||
3 | superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis | ||
4 | Drug metabolism - cytochrome P450 | ||
5 | Pyrimidine metabolism (KEGG) |
Pathways by source for DUT Gene
2 BioSystems pathways for DUT Gene
4 Reactome pathways for DUT Gene
3 KEGG pathways for DUT Gene
UniProtKB/Swiss-Prot P33316-DUT_HUMAN
- Pathway: Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.
Interacting Proteins for DUT Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001889 | liver development | IEA | -- |
GO:0006139 | nucleobase-containing compound metabolic process | TAS | 1325640 |
GO:0006226 | dUMP biosynthetic process | IEA | -- |
GO:0006260 | DNA replication | TAS | 1325640 |
GO:0009117 | nucleotide metabolic process | IEA | -- |
No data available for SIGNOR curated interactions for DUT Gene
Drugs & Compounds for DUT Gene
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Magnesium | Approved | Nutra | 0 | |||
Phosphoric acid | Approved | Pharma | 0 | |||
Water | Approved | Pharma | 0 | |||
1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE | Experimental | Pharma | Target | 0 | ||
Deoxyuridine-5'-Diphosphate | Experimental | Pharma | Target | 0 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
pyrophosphate |
|
14000-31-8 | ||||
Deoxyuridine triphosphate |
|
1173-82-6 |
|
|||
dUMP |
|
964-26-1 |
|
Transcripts for DUT Gene
mRNA/cDNA for DUT Gene
- (6) REFSEQ mRNAs :
- (15) Additional mRNA sequences :
- (417) Selected AceView cDNA sequences:
- (11) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for DUT Gene
- Deoxyuridine triphosphatase:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for DUT
- genomics-online: gRNA clones - Search results for available DUT gene related products
- Applied Biological Materials CRISPR for DUT
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for DUT
- GenScript: Design CRISPR guide RNA sequences for DUT
miRNA Products
- Search ViGene Biosciences for DUT
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for DUT
- Browse OriGene Inhibitory RNA Products For DUT
- genomics-online: shRNA clones - Search results for available DUT gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for DUT gene
Clone Products
-
OriGene ORF clones in human for DUT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for DUT
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for DUT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DUT
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available DUT gene related products
- orf clones - Search results for available DUT gene related products
- Applied Biological Materials Clones for DUT
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | · | 2f | · | 2g | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||
SP2: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||
SP3: | - | - | - | ||||||||||||||||||||||||||||||||||||
SP4: | - | - | |||||||||||||||||||||||||||||||||||||
SP5: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||
SP6: | - | - | |||||||||||||||||||||||||||||||||||||
SP7: | - | - | - | ||||||||||||||||||||||||||||||||||||
SP8: | - | ||||||||||||||||||||||||||||||||||||||
SP9: | - | - |
Expression for DUT Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for DUT Gene
NURSA nuclear receptor signaling pathways regulating expression of DUT Gene:
DUTSOURCE GeneReport for Unigene cluster for DUT Gene:
Hs.527980mRNA Expression by UniProt/SwissProt for DUT Gene:
P33316-DUT_HUMANEvidence on tissue expression from TISSUES for DUT Gene
- Nervous system(4.8)
- Lung(4.6)
- Liver(4.4)
- Blood(4.3)
- Eye(4.2)
- Intestine(2.1)
Primer Products
-
OriGene qPCR primer pairs for DUT
-
OriGene qPCR primer pairs and template standards for DUT
- genomics-online: primer clones - Search results for available DUT gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for DUT Gene
Orthologs for DUT Gene
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | DUT 33 34 |
|
||
cow (Bos Taurus) |
Mammalia | DUT 33 34 |
|
||
-- 34 |
|
OneToMany | |||
dog (Canis familiaris) |
Mammalia | DUT 33 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | DUT 34 |
|
OneToOne | |
mouse (Mus musculus) |
Mammalia | Dut 33 16 34 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
-- 34 |
|
OneToMany | |||
rat (Rattus norvegicus) |
Mammalia | Dut 33 |
|
||
chicken (Gallus gallus) |
Aves | DUT 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | DUT 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC101733437 33 |
|
||
Str.1294 33 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.7472 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | dut 33 34 |
|
||
wufa28d11 33 |
|
||||
rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.2007 33 |
|
||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP010159 33 |
|
||
fruit fly (Drosophila melanogaster) |
Insecta | dUTPase 33 34 |
|
||
worm (Caenorhabditis elegans) |
Secernentea | K07A1.2 35 |
|
|
|
dut-1 33 34 |
|
||||
A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AGR249C 33 |
|
||
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | DUT1 34 |
|
OneToOne | |
sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany | |
CSA.6436 34 |
|
OneToMany | |||
sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.2142 33 |
|
- Species where no ortholog for DUT was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for DUT Gene
Pseudogenes.org Pseudogenes for DUT Gene
No data available for Paralogs for DUT Gene
Variants for DUT Gene
SNP ID | Clin | Chr 15 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000573130 | -- | 48,340,162(+) | G/C | 3_prime_UTR_variant, intron_variant | |
rs1000625389 | -- | 48,340,411(+) | C/T | 3_prime_UTR_variant, intron_variant | |
rs1000785048 | -- | 48,333,216(+) | G/T | intron_variant | |
rs1001102963 | -- | 48,340,836(+) | C/T | downstream_transcript_variant, genic_downstream_transcript_variant, intron_variant | |
rs1001133842 | -- | 48,332,947(+) | A/T | intron_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2760030 | CNV | loss | 17122850 |
esv3569565 | CNV | gain | 25503493 |
esv3636412 | CNV | gain | 21293372 |
esv3636413 | CNV | loss | 21293372 |
nsv1053885 | CNV | gain | 25217958 |
Additional Variant Information for DUT Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DUT Gene
Disorders for DUT Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
cysticercosis |
|
|
Additional Disease Information for DUT
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for DUT Gene
Publications for DUT Gene
- Assignment of the human dUTPase gene (DUT) to chromosome 15q15-q21. 1 by fluorescence in situ hybridization. (PMID: 9070952) Cohen D … Pearlman RE (Genomics 1997) 2 3 4 22 58
- Human dUTP pyrophosphatase: cDNA sequence and potential biological importance of the enzyme. (PMID: 1325640) McIntosh EM … Haynes RH (Proceedings of the National Academy of Sciences of the United States of America 1992) 2 3 4 22 58
- Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase. (PMID: 17880943) Varga B … Vértessy BG (FEBS letters 2007) 3 4 22 58
- The human dUTPase gene encodes both nuclear and mitochondrial isoforms. Differential expression of the isoforms and characterization of a cDNA encoding the mitochondrial species. (PMID: 9228092) Ladner RD … Caradonna SJ (The Journal of biological chemistry 1997) 3 4 22 58
- Characterization of distinct nuclear and mitochondrial forms of human deoxyuridine triphosphate nucleotidohydrolase. (PMID: 8631816) Ladner RD … Caradonna SJ (The Journal of biological chemistry 1996) 3 4 22 58
Products for DUT Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for DUT
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for DUT
- Origene Custom Protein Services for DUT
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DUT
- Browse OriGene Inhibitory RNA Products For DUT
- OriGene qPCR primer pairs and template standards for DUT
- OriGene qPCR primer pairs for DUT
- OriGene CRISPR knockouts for DUT
- OriGene ORF clones in human for DUT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For DUT
- GenScript: Next-day shipping of latest version cDNA ORF clones for DUT in any vector
- GenScript Custom Purified and Recombinant Proteins Services for DUT
- GenScript Custom Assay Services for DUT
- GenScript Custom overexpressing Cell Line Services for DUT
- GenScript: Design CRISPR guide RNA sequences for DUT
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for DUT
- Sino Biological Human cDNA Clone for DUT
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for DUT
- Novus Biologicals proteins and lysates for DUT
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for DUT
- Abcam proteins for DUT
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ProSpec Recombinant Proteins for DUT
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for DUT
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for DUT
- VectorBuilder custom plasmid, inducible vectors for DUT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DUT
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 129 available DUT Antibodies ranked by validation data
- Compare Top DUT Antibodies
- antibodies-online: Search results for 5 available DUT Elisa Kits ranked by validation data
- Compare Top DUT Elisa Kits
- Quality Products:
- antibodies-online: Search results for 92 available DUT Proteins ranked by validation data
- Compare Top DUT Proteins
- GeneTex DUT antibody for DUT
- Search GeneTex for Proteins for DUT
- ViGene Biosciences adenoviral particle packaged cDNA for DUT gene
- ViGene Biosciences lentiviral particle packaged cDNA for DUT gene
- ViGene Biosciences ready-to-package AAV shRNAs for DUT gene
- Search ViGene Biosciences for DUT
- Santa Cruz Biotechnology (SCBT) Antibodies for DUT
- Search Santa Cruz Biotechnology (SCBT) for DUT siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for DUT
- Search for DUT Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for DUT
- genomics-online: cdna clones - Search results for available DUT gene related products
- orf clones - Search results for available DUT gene related products
- genomics-online: gRNA clones - Search results for available DUT gene related products
- genomics-online: primer clones - Search results for available DUT gene related products
- genomics-online: shRNA clones - Search results for available DUT gene related products
Sources for DUT Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew