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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DUSP23 Gene

protein-coding   GIFtS: 54
GCID: GC01P159750

dual specificity phosphatase 23
 Explore 5 diseases affiliated with
DUSP23 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for DUSP23    

Aliases
for DUSP23 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Dual Specificity Phosphatase 231 2     RP11-190A12.12
DUSP251 2     Dual Specificity Protein Phosphatase 232
Low Molecular Mass Dual Specificity Phosphatase 32 3     Low-Molecular-Mass Dual-Specificity Phosphatase 32
LDP-32 3     VH1-Like Member Z2
VHZ2 3     EC 3.1.3.163
VH1-Like Phosphatase Z2 3     EC 3.1.3.483
FLJ204421     LDP33
MOSP2     

External Ids:    HGNC: 214801   Entrez Gene: 549352   Ensembl: ENSG000001587167   UniProtKB: Q9BVJ73   

Export aliases for DUSP23 gene to outside databases

Previous GC identifers: GC01P156968 GC01P156563 GC01P158017 GC01P131107


Summaries
for DUSP23 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: DUS23_HUMAN, Q9BVJ7
Function: Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues.
In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation
of JNK and p38 (MAPK14)

Gene Wiki entry for DUSP23


Genomic Views
for DUSP23 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DUSP23 gene promoter:
         SRF   Spz1   Pbx1a   AP-1   SRF (504 AA)   ATF-2   LCR-F1   FOXJ2 (long isoform)   c-Jun   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DUSP23 promoter sequence
   Search SABiosciences Chromatin IP Primers for DUSP23

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DUSP23


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23.2   Ensembl cytogenetic band:  1q23.2   HGNC cytogenetic band: 1q23.1

DUSP23 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DUSP23 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P159750:  view genomic region     (about GC identifiers)

Start:
 159,750,722 bp from pter      End:
 159,752,333 bp from pter
Size:
 1,612 bases      Orientation:
 plus strand

Proteins
for DUSP23 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: DUS23_HUMAN, Q9BVJ7 (See protein sequence)
Recommended Name: Dual specificity protein phosphatase 23  
Size: 150 amino acids; 16588 Da
Subcellular location: Cytoplasm, cytosol. Nucleus. Note=Mainly cytosolic. Also nuclear
Caution: Was originally erroneously termed DUSP25
2 PDB 3D structures from and Proteopedia for DUSP23:
2IMG (3D)        4ERC (3D)    
Secondary accessions: Q9NX48

Explore the universe of human proteins at neXtProt for DUSP23: NX_Q9BVJ7

DUSP23 Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).

REFSEQ proteins: NP_060293.2  
ENSEMBL proteins: 
 ENSP00000357089   ENSP00000357088   ENSP00000357087  

Human Recombinant Protein Products: 
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OriGene Purified Protein: DUSP23
OriGene Protein Over-expression Lysate: DUSP23
OriGene Custom Protein Services for DUSP23 
GenScript Custom Purified and Recombinant Proteins Services for DUSP23
Novus Biologicals DUSP23 Proteins
Novus Biologicals DUSP23 Lysates
Browse Sino Biological Recombinant Proteins
ProSpec Recombinant Protein for DUSP23
Uscn Proteins for DUSP23

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IDA--
GO:0005730NOT nucleolus IDA--
GO:0005829cytosol IEA--
GO:0043231intracellular membrane-bounded organelle IDA--


DUSP23 for ontologies           About GeneDecksing



DUSP23 Antibody Products: 
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Uscn Antibodies for DUSP23
ThermoFisher Antibodies for DUSP23

Assay Products for DUSP23: 
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Uscn ELISAs and CLIAs for DUSP23

Protein Domains /
Families
for DUSP23 gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
DUSP23 for domains           About GeneDecksing

4 InterPro domains/families:
 IPR000387 Tyr/Dual-sp_Pase
 IPR026067 Dual_phosphatase_23
 IPR016130 Tyr_Pase_AS
 IPR000340 Dual-sp_phosphatase_cat-dom

Graphical View of Domain Structure for InterPro Entry Q9BVJ7

ProtoNet protein and cluster: Q9BVJ7

1 Blocks protein family: IPB000340 Dual specificity protein phosphatase

UniProtKB/Swiss-Prot: DUS23_HUMAN, Q9BVJ7
Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily
Similarity: Contains 1 tyrosine-protein phosphatase domain


Function
for DUSP23 gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section
Function Summary:

     UniProtKB/Swiss-Prot: DUS23_HUMAN, Q9BVJ7
Function: Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues.
In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation
of JNK and p38 (MAPK14)
Catalytic activity: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Catalytic activity: A phosphoprotein + H(2)O = a protein + phosphate
Biophysicochemical properties: Kinetic parameters: KM=1.498 mM for p-nitrophenylphosphate;

Enzyme Numbers (IUBMB): EC 3.1.3.161 EC 3.1.3.481

miRNA
Products:    		miRTarBase miRNAs that target DUSP23:
hsa-let-7b (MIRT001635)

OriGene 3'-UTR Clone: DUSP23
Browse MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DUSP23
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate DUSP23
SwitchGear 3'UTR luciferase reporter plasmid: DUSP23 3' UTR sequence
Inhib. RNA
Products:    		Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DUSP23 (see all 4)
OriGene shRNA RFP: DUSP23
OriGene siRNA: DUSP23
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DUSP23

Gene Editing
Products:		DNA2.0 Custom Protein Engineering Service for DUSP23

Clone
Products:     		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DUSP23 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DUSP23
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: DUSP23 (NM_017823)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for DUSP23
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DUSP23 

Cell Line
Products:     		GenScript Custom overexpressing Cell Line Services for DUSP23
Search LifeMap BioReagents cell lines for DUSP23

In Situ Assay
Products:   
 		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for DUSP23

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004725protein tyrosine phosphatase activity IEA--
GO:0008138protein tyrosine/serine/threonine phosphatase activity IEA--


DUSP23 for ontologies           About GeneDecksing


3 GenomeRNAi human phenotypes for DUSP23:
 Decreased viability  Increased cell elongation  Increased cell number in S and 


Pathways & Interactions
for DUSP23 gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DUSP23

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

5/22 Interacting proteins for DUSP23 (Q9BVJ72, 3 ENSP000003570874) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
InteractantInteraction Details
GeneCardExternal ID(s)
RPL8P629172, 3, ENSP000002625844MINT-65373 I2D: score=4 STRING: ENSP00000262584
C10orf118Q7Z3E22, 3, ENSP000003582934MINT-8254589 I2D: score=2 STRING: ENSP00000358293
C10orf137Q3B7T12, 3MINT-8254600 I2D: score=2 
DBIP071082, 3MINT-8254611 I2D: score=2 
DBN1Q166432, 3MINT-8254622 I2D: score=2 
About this table

Drugs & Compounds
for DUSP23 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DUSP23

1 DrugBank Compound for DUSP23    About this table
CompoundSynonyms CAS #TypeActionsPubMed Ids
4-Nitrophenyl Phosphate-- 330-13-2target--10592235

Search CenterWatch for drugs/clinical trials and news about DUSP23 / DUS23 

Transcripts
for DUSP23 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section
REFSEQ mRNAs for DUSP23 gene: 
NM_017823.3  

Unigene Cluster for DUSP23:

Dual specificity phosphatase 23
Hs.425801  [show with all ESTs]
Unigene Representative Sequence: BQ430655
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000368109(uc001fua.1) ENST00000368108(uc001ftz.1) ENST00000368107(uc001fub.1)


miRNA
Products:     		 OriGene 3'-UTR Clone: DUSP23
Browse OriGene MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DUSP23
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate DUSP23
SwitchGear 3'UTR luciferase reporter plasmid: DUSP23 3' UTR sequence
Inhib. RNA
Products:     		Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DUSP23 (see all 4)
OriGene shRNA RFP: DUSP23
OriGene siRNA: DUSP23
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DUSP23
Clone
Products:     		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DUSP23 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DUSP23
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: DUSP23 (NM_017823)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for DUSP23
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DUSP23 
Primer
Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DUSP23
Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DUSP23
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DUSP23
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DUSP23

Additional cDNA sequence: 

AB164404.1 AF086553.1 AK000449.1 BC001140.1 

6 DOTS entries:

DT.97799145  DT.112968  DT.97787382  DT.99989757  DT.100026441  DT.91826336 

24/114 AceView cDNA sequences (see all 114):

BF062579 BF221847 AI831878 AF086553 AA479435 BE263806 AI739584 AA478731 
AI382796 CB106751 AI363485 AB164404 AI686408 BC001140 BI761974 BU157259 
AA662156 BU738941 BM547541 BM676758 BU177833 AI223430 BM719897 AI493390 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for DUSP23    About this scheme

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c
SP1:                                                
SP2:                    -                           
SP3:                                                


ECgene alternative splicing isoforms for DUSP23

Expression
for DUSP23 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DUSP23 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGTCGATGG

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)
About this image

DUSP23 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
Stem Cell Differentiation: 1 LifeMap Cell 
NameCategory
PureStem™ progenitor SK17 (Embryonic Progenitor Cell)
Expression: Positive    Negative     Selective marker
Experimental details: Curated     Microarrays     In-situ hybridization

See DUSP23 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DUSP23

SOURCE GeneReport for Unigene cluster: Hs.425801

UniProtKB/Swiss-Prot: DUS23_HUMAN, Q9BVJ7
Tissue specificity: Widely expressed. Highly expressed in spleen, prostate, colon, adrenal gland, mammary gland,
thyroid and trachea. Expressed at lower level in uterus, small intestine, bladder, bone marrow, brain, spinal cord and
stomach

    SABiosciences Expression via Pathway-Focused PCR Array including DUSP23: 
          Protein Phosphatases in human mouse rat

Primer
Products:		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DUSP23
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QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DUSP23
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DUSP23
In Situ
Assay Products: 
 		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for DUSP23

Orthologs
for DUSP23 gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
This gene was present in the common ancestor of chordates.

Orthologs for DUSP23 gene from 5/17 species (see all 17)    About this table
Organism Taxonomic
classification		 Gene Description Human
Similarity		 Orthology
Type		 Details
mouse
(Mus musculus)		 Mammalia Dusp231 , 5 dual specificity phosphatase 231, 5 89.33(n)1
95.33(a)1		   1 (80.05 cM)5
684401  NM_026725.21  NP_081001.11 
 1726307695 
chicken
(Gallus gallus)		 Aves LOC1008588731 dual specificity protein phosphatase 23-like 71.46(n)
67.12(a)		   100858873  XM_003642664.1  XP_003642712.1 
lizard
(Anolis carolinensis)		 Reptilia DUSP236
 --
 71(a)
 1 ↔ 1
 GL344296.1(37471-39285)
African clawed frog
(Xenopus laevis)		 Amphibia Xl.159412 Xenopus laevis transcribed sequence with weak similarity more 72.9(n)    BX844527.1 
zebrafish
(Danio rerio)		 Actinopterygii Dr.80082 Transcribed sequence with weak similarity to protein more 76.02(n)    57073919 


ENSEMBL Gene Tree for DUSP23 (if available)
TreeFam Gene Tree for DUSP23 (if available) 

Paralogs
for DUSP23 gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for DUSP23 gene
CDC14A2  CDC14B2  
3 SIMAP similar genes for DUSP23 using alignment to 1 protein entry:     DUS23_HUMAN:
CDC14A    CDC14B    MGC26484

DUSP23 for paralogs           About GeneDecksing



Genomic Variants
for DUSP23 gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/65 NCBI SNPs in DUSP23 are shown (see all 65)     About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance		Chr 1 posSequence#AA
Chg		TypeMore#Allele
freq		PopTotal
sample		More
----------
rs1904283611,2
--159748822(+) AGGGGA/CCTCAG 1 -- us2k10--------
rs38061841,2
C,F,A,--159748866(+) TTCTCC/TTTCTG 1 -- us2k1 tfbs3 trp311Minor allele frequency- T:0.32WA NA CSA EA 372
rs38061851,2
C,F,A,H,--159748886(+) GGCTTC/TGAGCT 1 -- us2k122Minor allele frequency- T:0.19NS EA NA WA 2756
rs1427457491,2
--159748905(+) AGGAGA/GCAAAG 1 -- us2k10--------
rs1473804091,2
--159748908(+) AGGCAA/TAGAAG 1 -- us2k10--------
rs766151651,2
C,F,--159748951(+) ACTTCC/TCTGGT 1 -- us2k11Minor allele frequency- T:0.03WA 118
rs722326561,2
C--159749041(+) TGTCT-/CCAGAG
GTAGTGCAACCAGA 		1 -- us2k10--------
rs1504869051,2
C,--159749041(+) TGTCT-/CCAGAG
GTAGTGCAACCAGA 		1 -- us2k10--------
rs38404241,2
C--159749046(+) CCAGA-/GGTAGT
GCAACCAGAAATCC 		1 -- us2k11Minor allele frequency- GGTAGTGCAACCAGA:0.00NA 2
rs38061861,2
C,F,A,--159749110(+) GGGGTT/GGGGGG 1 -- us2k110Minor allele frequency- G:0.47NA WA CSA EA 372

HapMap Linkage Disequilibrium report for DUSP23 (159750722 - 159752333 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for DUSP23: --
Human Gene Mutation Database (HGMD): DUSP23

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DUSP23
DNA2.0 Custom Variant and Variant Library Synthesis for DUSP23

Disorders / Diseases
for DUSP23 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
DUSP23 for disorders           About GeneDecksing

5 diseases for DUSP23:    About MalaCards
dental enamel hypoplasia    esophagitis    thyroiditis    adenocarcinoma
prostatitis

1 disease from the University of Copenhagen DISEASES database for DUSP23:
Dental enamel hypoplasia
Human Genome Epidemiology (HuGE) Navigator: DUSP23 (5 documents)

Export disorders for DUSP23 gene to outside databases

Publications
for DUSP23 gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for DUSP23 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with DUSP23)		    Utopia: connect your pdf to the dynamic
world of online information

  1. Molecular cloning and characterization of a novel dual-specificity phosphatase 23 gene from human fetal brain. (PubMed id 15147733)1, 2, 3, 9 Wu Q....Mao Y. (2004)
  2. The minimal essential core of a cysteine-based protein-tyrosine phosphatase revealed by a novel 16-kDa VH1-like phosphatase, VHZ. (PubMed id 15201283)1, 2, 9 Alonso A.... Mustelin T. (2004)
  3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
  4. Characterization of a novel low-molecular-mass dual-specificity phosphatase-3 (LDP-3) that enhances activation of JNK and p38. (PubMed id 15281913)1, 2 Takagaki K....Kikuchi K. (2004)
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
  7. Structure of human dual specificity protein phosphatase 23, VHZ, enzyme-substrate/product complex. (PubMed id 18245086)2, 9 Agarwal R....Swaminathan S. (2008)
  8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
  9. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
  10. Dual-specificity phosphatase 23 mediates GCM1 dephosp horylation and activation. (PubMed id 20855292)1 Lin F.Y....Chen H. (2011)

External Searches for DUSP23 gene

(in PubMed, OMIM, and NCBI Bookshelf)
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Genome Databases showing DUSP23 gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 54935 HGNC: 21480 AceView: DUSP23 Ensembl:ENSG00000158716 euGenes: HUgn54935
ECgene: DUSP23 H-InvDB: DUSP23

Other Databases showing DUSP23 gene

(According to HUGE)
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Specialized Databases showing DUSP23 gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for DUSP23 Pharmacogenomics, SNPs, Pathways

Intellectual Property
for DUSP23 gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for DUSP23 gene:
Search GeneIP for patents involving DUSP23

GeneCards and IP:
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Products
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