Aliases for DUSP21 Gene
External Ids for DUSP21 Gene
This gene encodes a member of the dual specificity phosphatase family, specifically the low molecular weight dual specificity phosphatase family. The encoded protein localizes to both the cytoplasm and the nucleus and functions to remove phosphate groups from phosphotyrosine and phosphothreonine residues.[provided by RefSeq, Mar 2009]
GeneCards Summary for DUSP21 Gene
DUSP21 (Dual Specificity Phosphatase 21) is a Protein Coding gene. Diseases associated with DUSP21 include colorectal cancer. GO annotations related to this gene include protein tyrosine phosphatase activity and MAP kinase tyrosine/serine/threonine phosphatase activity. An important paralog of this gene is DUSP26.
UniProtKB/Swiss-Prot for DUSP21 Gene
Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine