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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DUSP19 Gene

protein-coding GIFtS: 51
GCID: GC02P183907

dual specificity phosphatase 19

Explore 79 diseases affiliated with
DUSP19 via

MalaCards

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Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Dual Specificity Phosphatase 19¹ ²		LMW-DSP3² ³
DUSP17¹ ² ³		LMWDSP3² ³
SKRP1¹ ² ³		SAPK Pathway-Regulating Phosphatase 1² ³
Dual Specificity Phosphatase TS-DSP1² ³		TS-DSP1²
Low Molecular Weight Dual Specificity Phosphatase 3² ³		Dual Specificity Protein Phosphatase 19²
Protein Phosphatase SKRP1² ³		EC 3.1.3.16³
Stress-Activated Protein Kinase Pathway-Regulating Phosphatase 1² ³		EC 3.1.3.48³

External Ids:	HGNC: 18894¹	Entrez Gene: 142679²	Ensembl: ENSG00000162999⁷	OMIM: 611437⁵	UniProtKB: Q8WTR2³

Export aliases for DUSP19 gene to outside databases

Previous GC identifers: GC02P182626 GC02P184146 GC02P183768 GC02P183651 GC02P175802

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DUSP19:

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based

protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine

and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19

contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by

alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of

DUSPs (see MIM 600714) (summary by Patterson et al., 2009 (PubMed 19228121)).(supplied by OMIM, Dec 2009)

UniProtKB/Swiss-Prot: DUS19_HUMAN, Q8WTR2

Function: Has a dual specificity toward Ser/Thr and Tyr-containing proteins

Gene Wiki entry for DUSP19

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_005403.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DUSP19 gene promoter:
STAT1 AML1a AP-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DUSP19 promoter sequence

Search SABiosciences Chromatin IP Primers for DUSP19

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DUSP19

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q32.1 Ensembl cytogenetic band: 2q32.1 HGNC cytogenetic band: 2q32.1

DUSP19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DUSP19 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P183907: view genomic region (about GC identifiers)

Start:	183,943,287 bp from pter	End:	183,964,736 bp from pter
Size:	21,450 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DUS19_HUMAN, Q8WTR2 (See protein sequence)

Recommended Name: Dual specificity protein phosphatase 19

Size: 217 amino acids; 24194 Da

1 PDB 3D structure from and Proteopedia for DUSP19:

3S4E (3D)

Secondary accessions: B2RA79 Q547H4 Q8WYN4

Alternative splicing: 2 isoforms: Q8WTR2-1 Q8WTR2-2

Explore the universe of human proteins at neXtProt for DUSP19: NX_Q8WTR2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8WTR2

DUSP19 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001135786.1 NP_543152.1

ENSEMBL proteins:

ENSP00000343905 ENSP00000346160

Human Recombinant Protein Products:

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	Uscn Proteins for DUSP19

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IBA	--

DUSP19 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

DUSP19 for domains About GeneDecksing

5 InterPro domains/families:

IPR000387 Tyr/Dual-sp_Pase

IPR020422 Dual-sp_phosphatase_subgr_cat

IPR020417 Atypical_DUSP

IPR024950 DUSP

IPR000340 Dual-sp_phosphatase_cat-dom

Graphical View of Domain Structure for InterPro Entry Q8WTR2

ProtoNet protein and cluster: Q8WTR2

1 Blocks protein family: IPB000340 Dual specificity protein phosphatase

UniProtKB/Swiss-Prot: DUS19_HUMAN, Q8WTR2

Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily

Similarity: Contains 1 tyrosine-protein phosphatase domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: DUS19_HUMAN, Q8WTR2

Function: Has a dual specificity toward Ser/Thr and Tyr-containing proteins

Catalytic activity: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate

Catalytic activity: A phosphoprotein + H(2)O = a protein + phosphate

Enzyme Numbers (IUBMB): EC 3.1.3.16¹ EC 3.1.3.48¹

miRNA Products:		OriGene 3'-UTR Clone (see all 2): DUSP19 Browse MicroRNA Expression Plasmids
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		hsa-miR-576-3p hsa-miR-19b-2* hsa-miR-139-5p hsa-let-7a-2* hsa-miR-3653 hsa-miR-374a hsa-miR-29b-1* hsa-miR-548l

		SwitchGear 3'UTR luciferase reporter plasmid: DUSP19 3' UTR sequence

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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DUSP19

Gene Ontology (GO): 5/9 molecular function terms (GO ID links to tree view) (see all 9): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004725	protein tyrosine phosphatase activity	IEA	--
GO:0004860	protein kinase inhibitor activity	ISS	--
GO:0005078	MAP-kinase scaffold activity	ISS	--
GO:0005515	protein binding	--	--
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	--	--

DUSP19 for ontologies About GeneDecksing

3 GenomeRNAi human phenotypes for DUSP19:

Increased Akt phosphorylation

Increased S DNA content

Increased apoptosis

Animal Models:
Mouse knock-out Dusp19^tm1Lex for DUSP19
1 MGI phenotypic allele

for Dusp19 (no phenotypes)

DUSP19 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for DUSP19

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

5 Interacting proteins for DUSP19 (Q8WTR2³ ENSP00000346160⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
MAP2K7	O14733³, ENSP00000381066⁴	I2D: score=3 STRING: ENSP00000381066
MAP3K5	Q99683³, ENSP00000351908⁴	I2D: score=3 STRING: ENSP00000351908
MAPK9	P45984³, ENSP00000321410⁴	I2D: score=2 STRING: ENSP00000321410
ALAS1	P13196³	I2D: score=1
ELAVL1	ENSP00000385269⁴	STRING: ENSP00000385269

About this table

Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000188	inactivation of MAPK activity	IEA	--
GO:0006469	negative regulation of protein kinase activity	ISS	--
GO:0006470	protein dephosphorylation	IBA	--
GO:0007254	JNK cascade	IBA	--
GO:0043410	positive regulation of MAPK cascade	ISS	--

DUSP19 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

DUSP19 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DUSP19

3 HMDB Compounds for DUSP19 About this table

Compound	Synonyms	CAS #	PubMed Ids
Calcium	Ca (see all 2)	7440-70-2	--
Phosphate	NFB Orthophosphate (see all 13)	14265-44-2	--
Water	Dihydrogen oxide (see all 2)	7732-18-5	--

10/123 Novoseek chemical compound relationships for DUSP19 gene (see all 123) About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
okadaic acid	96	319	1328535 (3), 1663450 (3), 7698228 (3), 7927883 (3) (see all 99)
calyculin a	94.5	123	12802629 (2), 10522205 (2), 7931558 (2), 8581989 (2) (see all 92)
tautomycin	88.8	20	9605423 (3), 10493981 (2), 1556018 (2), 8581989 (2) (see all 14)
microcystin-lr	85	25	16046071 (2), 12176093 (2), 11137546 (1), 10669024 (1) (see all 19)
threonine	84.1	47	7771789 (2), 1384163 (1), 11875759 (1), 17030510 (1) (see all 44)
serine	78.1	52	7771789 (2), 7566342 (1), 11875759 (1), 17030510 (1) (see all 48)
fostriecin	78.1	4	12536807 (1), 14677930 (1), 12624107 (1), 9215602 (1)
motuporin	74.1	1	7749913 (1)
cantharidin	74.1	6	12559002 (1), 15807782 (1), 15667592 (1), 9809469 (1) (see all 6)
nodularin	73.8	8	15892066 (1), 10669024 (1), 16304634 (1), 10578179 (1) (see all 8)

Search CenterWatch for drugs/clinical trials and news about DUSP19 / DUS19

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DUSP19 gene (2 alternative transcripts):

NM_001142314.1 NM_080876.3

Unigene Cluster for DUSP19:

Dual specificity phosphatase 19

Hs.132237 [show with all ESTs]

Unigene Representative Sequence: NM_080876

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000342619 ENST00000354221(uc002upd.3 uc010frp.3 uc010zfr.2 uc002upe.3)

ENST00000469344

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		hsa-miR-576-3p hsa-miR-19b-2* hsa-miR-139-5p hsa-let-7a-2* hsa-miR-3653 hsa-miR-374a hsa-miR-29b-1* hsa-miR-548l

		SwitchGear 3'UTR luciferase reporter plasmid: DUSP19 3' UTR sequence

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Additional cDNA sequence:

AB038770.1 AB063186.1 AB063187.1 AK094800.1 AK125657.1 AK314078.1 BC035000.1 BC093958.1

BC112005.1 BC143337.1 BX647818.1

4 DOTS entries:

DT.205994 DT.100016082 DT.97835667 DT.99940729

24/31 AceView cDNA sequences (see all 31):

AB038770 AB063186 BU160622 AK125657 AB063187 AA442636 BX496415 AA442646

AI031656 AK094800 BX957037 AF486808 NM_080876 BX647818 BG116871 AI025365

CA776730 BX111317 BC035000 AW772089 CA776500 AI033989 N63762 AW172742

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for DUSP19 About this scheme

ExUns:	1a	·	1b	^	2	^	3a	·	3b	^	4
SP1:
SP2:							-		-
SP3:							-

ECgene alternative splicing isoforms for DUSP19

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DUSP19 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TACCCTTTAT

About this image
See DUSP19 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DUSP19

SOURCE GeneReport for Unigene cluster: Hs.132237

UniProtKB/Swiss-Prot: DUS19_HUMAN, Q8WTR2

Tissue specificity: Expressed in the heart, lung, liver, and pancreas. The expression level in the pancreas is the

highest

SABiosciences Custom PCR Arrays for DUSP19

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DUSP19

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for DUSP19 gene from 6/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	DUSP19¹	dual specificity phosphatase 19	70.83(n) 78.5(a)		423999 XM_421855.3 XP_421855.2
lizard (Anolis carolinensis)	Reptilia	DUSP19⁶	--	75(a)	1 ↔ 1	GL343221.1(1886231-1890154)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.15392²	Transcribed sequence with weak similarity to protein more	73.78(n)		BX704055.1
zebrafish (Danio rerio)	Actinopterygii	dusp19¹	dual specificity phosphatase 19	64.49(n) 64.82(a)		792815 NM_001128265.1 NP_001121737.1
fruit fly (Drosophila melanogaster)	Insecta	Mkp⁶	MAP kinase-specific phosphatase	40(a)	1 ↔ 1	3L(182522-184422)
worm (Caenorhabditis elegans)	Secernentea	Y54F10BM.13⁶	--	33(a)	1 ↔ 1	III(2329573-2331173)

ENSEMBL Gene Tree for DUSP19 (if available)
TreeFam Gene Tree for DUSP19 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for DUSP19 gene

DUSP4² DUSP21² SSH2² DUSP10² DUSP6² DUSP14² DUSP28² DUSP8²

DUSP7² DUSP5² SSH3² DUSP16² DUSP9² DUSP2² DUSP18² SSH1²

DUSP1²

13 SIMAP similar genes for DUSP19 using alignment to 1 protein entry: DUS19_HUMAN:

DUSP10 DUSP6 DUSP7 SSH3 DUSP15 DUSP18

SSH2 DUSP21 SSH1 STYX DUSP9 DUSP3

DUSP22

DUSP19 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs148988606^1,2		--	183941361(+)	`TATTCA/GTTAAC`	2	--	us2k¹		0	--	--	--	--
rs2675043^1,2	C,F,A,H,	--	183941444(+)	`GGTTTT/CATTTG`	2	--	us2k¹		16		NS EA NA CSA WA	2136
rs111870652^1,2		--	183941471(+)	`TAGGGG/ATGAGG`	2	--	us2k¹		1		CSA	2
rs2944344^1,2	C,A,	--	183941783(+)	`cttttC/Tttttt`	2	--	us2k¹ trp³		0	--	--	--	--
rs2368354^1,2	C,H,	--	183942007(+)	`GTCTCC/GAACTC`	2	--	us2k¹		5		NA	12
rs138587619^1,2		--	183942064(+)	`TTACAG/TGCATG`	2	--	us2k¹		0	--	--	--	--
rs2675086^1,2	C,F,H,	--	183942093(-)	`GAAAAG/AGGAAT`	2	--	us2k¹ trp³		18		NS EA WA NA CSA	1177
rs144094672^1,2		--	183942179(+)	`ACAACC/TGAAAT`	2	--	us2k¹		0	--	--	--	--
rs182990424^1,2		--	183942582(+)	`TTTTCA/GTAAGT`	2	--	us2k¹		0	--	--	--	--
rs16823968^1,2	C,F,H,	--	183942620(+)	`TATACA/GTTGTG`	2	--	us2k¹		15		NA NS EA WA CSA	1358

HapMap Linkage Disequilibrium report for DUSP19 (183943287 - 183964736 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DUSP19: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DUSP19

DNA2.0 Custom Variant and Variant Library Synthesis for DUSP19

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DUSP19 for disorders           About GeneDecksing

OMIM gene information: 611437    OMIM disorders: --

20/79 diseases for DUSP19 (see all 79):    About MalaCards

congenital cataracts, facial dysmorphism, and neuropathy malignant fibrous histiocytoma fibrous histiocytoma dna topoisomerase i

amyotrophic lateral sclerosis myoclonus epilepsy progressive myoclonus epilepsy osteochondroma

lafora disease cowden disease lateral sclerosis histiocytoma

myoclonus congenital cataracts sleep apnea insulin resistance

atrial fibrillation malignant glioma lipoma cystic teratoma

10/59 Novoseek disease relationships for DUSP19 gene (see all 59) About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
paired helical filament	59.2	1	9129864 (1)
lafora disease	53.8	2	16311711 (1), 16971387 (1)
harlequin ichthyosis	45.4	3	7694551 (2), 9470902 (1)
retinoblastoma	42.3	6	11593419 (1), 10874474 (1), 7499444 (1), 8663484 (1) (see all 6)
neurofibrillary tangles	41.9	3	18430997 (1), 8720139 (1), 18852562 (1)
cowden disease	41.8	1	10051603 (1)
alzheimers disease	35.9	13	7616230 (2), 7787767 (1), 8624075 (1), 16953147 (1) (see all 12)
glioblastoma	32.5	2	16294307 (1), 19915616 (1)
myeloid leukemia	32	6	8389250 (1), 1334850 (1), 18796247 (1), 9204972 (1) (see all 6)
promyelocytic leukemia	24.8	1	9894151 (1)

Export disorders for DUSP19 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DUSP19 gene, integrated from 9 sources (see all 829):
(articles sorted by number of sources associating them with DUSP19)

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Molecular cloning and characterization of a novel human protein phosphatase, LMW-DSP3. (PubMed id 12479873)^{1, 2, 9} Cheng H.... Mao Y. (2003)
Crystal structure of a novel mitogen-activated protei n kinase phosphatase, SKRP1. (PubMed id 21989941)^{1, 2} Wei C.H....Ryu S.E. (2011)
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)^{1, 2} Hillier L.W....Wilson R.K. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway. (PubMed id 11959862)^{1, 2} Zama T.... Hagiwara M. (2002)
Dual-specificity phosphatases: critical regulators with diverse cellular targets. (PubMed id 19228121)^{1, 9} Patterson K.I....Daly R.J. (2009)
Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)¹ Abdelmohsen K....Gorospe M. (2009)
A novel dual specificity phosphatase SKRP1 interacts with the MAPK kinase MKK7 and inactivates the JNK MAPK pathway. Implication for the precise regulation of the particular MAPK pathway. (PubMed id 11959861)¹ Zama T....Hagiwara M. (2002)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 142679	HGNC: 18894	AceView: DUSP19	Ensembl:ENSG00000162999	euGenes: HUgn142679
ECgene: DUSP19	H-InvDB: DUSP19

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for DUSP19	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DUSP19 gene
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Patent Information for DUSP19 gene:
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dual specificity phosphatase 19

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DUSP19 Gene

dual specificity phosphatase 19

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