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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DUSP18 Gene

protein-coding   GIFtS: 49
GCID: GC22M031048

Dual Specificity Phosphatase 18

  Search for DUSP18
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Dual Specificity Phosphatase 181 2     DUSP202
Low Molecular Weight Dual Specificity Phosphatase 202 3     bK963H5.12
LMW-DSP202 3     Dual Specificity Protein Phosphatase 182
LMWDSP202 3     EC 3.1.3.163
DSP182     EC 3.1.3.483

External Ids:    HGNC: 184841   Entrez Gene: 1502902   Ensembl: ENSG000001670657   OMIM: 6114465   UniProtKB: Q8NEJ03   

Export aliases for DUSP18 gene to outside databases

Previous GC identifers: GC22M027744 GC22M029372 GC22M029382 GC22M014021


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DUSP18 Gene:
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based
protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both
tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling
pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain
found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by
Patterson et al., 2009 (PubMed 19228121)).(supplied by OMIM, Dec 2009)

GeneCards Summary for DUSP18 Gene: 
DUSP18 (dual specificity phosphatase 18) is a protein-coding gene. GO annotations related to this gene include MAP kinase tyrosine/serine/threonine phosphatase activity and protein tyrosine phosphatase activity. An important paralog of this gene is DUSP4.

UniProtKB/Swiss-Prot: DUS18_HUMAN, Q8NEJ0
Function: Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the
phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl
phosphate (pNPP)

Gene Wiki entry for DUSP18 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NT_011520.12  NC_018933.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DUSP18 gene promoter:
         SRF   NF-1   NF-1/L   Pax-5   SRF (504 AA)   Roaz   C/EBPalpha   Evi-1   CP2   SEF-1 (1)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDUSP18 promoter sequence
   Search SABiosciences Chromatin IP Primers for DUSP18

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DUSP18


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q12.2   Ensembl cytogenetic band:  22q12.2   HGNC cytogenetic band: 22q12.1

DUSP18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DUSP18 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M031048:  view genomic region     (about GC identifiers)

Start:
31,048,038 bp from pter      End:
31,063,877 bp from pter
Size:
15,840 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DUS18_HUMAN, Q8NEJ0 (See protein sequence)
Recommended Name: Dual specificity protein phosphatase 18  
Size: 188 amino acids; 21066 Da
Subcellular location: Cytoplasm. Nucleus
1 PDB 3D structure from and Proteopedia for DUSP18:
2ESB (3D)    
Secondary accessions: B3KPA4

Explore the universe of human proteins at neXtProt for DUSP18: NX_Q8NEJ0

Explore proteomics data for DUSP18 at MOPED 

DUSP18 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

DUSP18 Protein Expression

REFSEQ proteins: NP_689724.3  
ENSEMBL proteins: 
 ENSP00000414825   ENSP00000385463   ENSP00000386063   ENSP00000366291   ENSP00000387680  
 ENSP00000384946   ENSP00000333917   ENSP00000340795   ENSP00000403378  

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Novus Biologicals DUSP18 Proteins
Novus Biologicals DUSP18 Lysates
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ProSpec Recombinant Protein for DUSP18
Cloud-Clone Corp. Proteins for DUSP18 

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IDA12408986
GO:0005737cytoplasm IDA12408986

DUSP18 for ontologies           About GeneDecksing



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LSBio Antibodies in human, mouse, rat for DUSP18 

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Cloud-Clone Corp. CLIAs for DUSP18


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
DUSPA: Protein tyrosine phosphatases / Class I Cys-based PTPs : Atypical dual specificity phosphatases

5/6 InterPro protein domains (see all 6):
 IPR020422 Dual-sp_phosphatase_subgr_cat
 IPR016130 Tyr_Pase_AS
 IPR020417 Atypical_DUSP
 IPR024950 DUSP
 IPR000340 Dual-sp_phosphatase_cat-dom

Graphical View of Domain Structure for InterPro Entry Q8NEJ0

ProtoNet protein and cluster: Q8NEJ0

1 Blocks protein domain: IPB000340 Dual specificity protein phosphatase

UniProtKB/Swiss-Prot: DUS18_HUMAN, Q8NEJ0
Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily
Similarity: Contains 1 tyrosine-protein phosphatase domain


DUSP18 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: DUS18_HUMAN, Q8NEJ0
Function: Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the
phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl
phosphate (pNPP)
Catalytic activity: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Catalytic activity: A phosphoprotein + H(2)O = a protein + phosphate
Enzyme regulation: Activated by manganese ions, inhibited by iodoaretic acid
Biophysicochemical properties: pH dependence: Optimum pH is 6.0; Temperature dependence: Optimum temperature is 55
degrees Celsius;

     Enzyme Numbers (IUBMB): EC 3.1.3.161 EC 3.1.3.481

     Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004725protein tyrosine phosphatase activity IDA12408986
GO:0008138protein tyrosine/serine/threonine phosphatase activity IBA--
GO:0016791phosphatase activity ----
GO:0017017MAP kinase tyrosine/serine/threonine phosphatase activity IEA--
     
DUSP18 for ontologies           About GeneDecksing


Phenotypes:
     4 GenomeRNAi human phenotypes for DUSP18:
 Decreased TP53 protein express  Decreased focal adhesion (FA)   Elongated cells  Stronger migration 

Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for DUSP18 
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miRNA
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SwitchGear 3'UTR luciferase reporter plasmidDUSP18 3' UTR sequence
Inhib. RNA
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DUSP18
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Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DUSP18


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DUSP18

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006470protein dephosphorylation ----
GO:0016311dephosphorylation ----
GO:0035335peptidyl-tyrosine dephosphorylation IDA12408986

DUSP18 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DUSP18 (DUS18)

4 HMDB Compounds for DUSP18    About this table
CompoundSynonyms CAS #PubMed Ids
CalciumCa (see all 2)7440-70-2--
Manganesemanganese 7439-96-5--
PhosphateNFB Orthophosphate (see all 13)14265-44-2--
WaterDihydrogen oxide (see all 2)7732-18-5--

Search CenterWatch for drugs/clinical trials and news about DUSP18 / DUS18

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DUSP18 gene: 
NM_152511.3  

Unigene Cluster for DUSP18:

Dual specificity phosphatase 18
Hs.517544  [show with all ESTs]
Unigene Representative Sequence: BC028724
10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000430175 ENST00000404885 ENST00000407308(uc003aiu.3) ENST00000461301
ENST00000377087 ENST00000412865 ENST00000403268(uc010gwa.2) ENST00000334679(uc003aiw.1)
ENST00000342474 ENST00000442752
miRNA
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SwitchGear 3'UTR luciferase reporter plasmidDUSP18 3' UTR sequence
Inhib. RNA
Products:
     
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Sirion Biotech Customized lentivirus for stable overexpression of DUSP18 
                     Customized lentivirus expression plasmids for stable overexpression of DUSP18 
Primer
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  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DUSP18
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DUSP18

Additional mRNA sequence: 

AF461689.1 AF533017.1 AK025036.1 AK056074.1 BC004110.2 BC028724.1 BC030987.1 CR456406.1 

5 DOTS entries:

DT.109710  DT.100750066  DT.95373433  DT.99954797  DT.95282389 

24/83 AceView cDNA sequences (see all 83):

CD675112 BE222374 BE222542 CR456406 AI699242 AA431991 BU584603 BM759289 
AI283262 AF533017 BX090660 AI299221 NM_152511 BC030987 BM833888 AA393396 
BX279710 AA634547 BE670431 BI907369 AI215158 BC028724 BU584240 AL711163 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DUSP18 expression in normal human tissues (normalized intensities)      DUSP18 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AATGATAGAC
DUSP18 Expression
About this image


DUSP18 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/32 selected tissues (see all 32) fully expand
 
 Epithelium
         vagina ; squamous epithelial cells   
         bronchial epithelial cells   
 
 Testis (Reproductive System)    fully expand to see all 4 entries
         Leydig Cells Testis Interstitium
         seminal vesicle ; glandular cells   
 
 Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
         colon ; peripheral nerve/ganglion   
 
 Brain (Nervous System)    fully expand to see all 3 entries
         Cerebral Cortex
 
 Breast
         breast ; myoepithelial cells   

See DUSP18 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DUSP18

SOURCE GeneReport for Unigene cluster: Hs.517544

UniProtKB/Swiss-Prot: DUS18_HUMAN, Q8NEJ0
Tissue specificity: Widely expressed with highest levels in liver, brain, ovary and testis

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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DUSP18

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for DUSP18 gene from 5/12 species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Dusp181 , 5 dual specificity phosphatase 181, 5 82.45(n)1
82.45(a)1
  11 (2.74 cM)5
752191  NM_173745.51  NP_776106.11 
 38952405 
chicken
(Gallus gallus)
Aves DUSP181 dual specificity phosphatase 18 68.46(n)
64.07(a)
  417005  XM_415295.3  XP_415295.3 
lizard
(Anolis carolinensis)
Reptilia --
Uncharacterized protein
63(a)
1 → many
GL343417.1(197291-197857)
zebrafish
(Danio rerio)
Actinopterygii DUSP216
CABZ01071036.16
(see all 3)
Uncharacterized protein
(see all 3)
47(a)
36(a)
(see all 3)
1 ↔ many
possible ortholog
(see all 3)
5(72402198-72404174)
2(43757513-43758022)
worm
(Caenorhabditis elegans)
Secernentea F13D11.36
F26A3.46
(see all 4)
Protein F26A3.4
(see all 4)
29(a)
27(a)
(see all 4)
many ↔ many
many ↔ many
(see all 4)
X(5804387-5805924)
I(7656907-7658293)


ENSEMBL Gene Tree for DUSP18 (if available)
TreeFam Gene Tree for DUSP18 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for DUSP18 gene
DUSP42  DUSP212  SSH22  DUSP102  DUSP62  DUSP142  DUSP282  DUSP82  
DUSP72  DUSP52  SSH32  DUSP162  DUSP92  DUSP22  SSH12  DUSP12  
12 SIMAP similar genes for DUSP18 using alignment to 5 protein entries:     DUS18_HUMAN (see all proteins):
DUSP21    DUSP14    DUSP19    DUSP10    DUSP13    DUSP8
DUSP16    DUSP15    DUSP3    DUSP7    DUSP22    DUSP28

DUSP18 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/210 SNPs in DUSP18 are shown (see all 210)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 22 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs96090371,2
C--31057584(+) gcaccT/CAGCTG 1 -- ds50013Minor allele frequency- C:0.17NA 6
rs113257611,2
C--31057590(+) AGCTG-/TTAAAA 1 -- ds50010--------
rs763528041,2
F--31057695(+) CTCTGG/CATCAG 1 -- ds50011Minor allele frequency- C:0.04WA 118
rs1817017411,2
C--31057697(+) CTGGAC/TCAGAA 1 -- ds50010--------
rs1410400231,2
C--31057741(+) AGGATA/GTGAAC 1 -- ds50010--------
rs1861452671,2
--31057801(+) GACACA/GGCCCC 1 -- ds50010--------
rs1163861771,2
F--31057830(+) CAGCCG/AGGGTG 1 -- ds50011Minor allele frequency- A:0.03WA 118
rs1444063121,2
C--31057923(+) CAGGA-/CCTC  
  TAGATT
GCACC
1 -- ds50010--------
rs1901221621,2
--31057988(+) CTCCTA/GTGAGG 1 -- ds50010--------
rs86301,2
C,F,A,H--31058115(-) CATCCT/CCATAA 1 -- ut31 ese331Minor allele frequency- C:0.37MN NS EA NA WA CSA 3401

HapMap Linkage Disequilibrium report for DUSP18 (31048038 - 31063877 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for DUSP18:    About this table     
Variant IDTypeSubtypePubMed ID
nsv834175CNV Gain17160897

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing DUSP18
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DUSP18 for disorders           About MalaCards
OMIM gene information: 611446    OMIM disorders: --


DUSP18 for disorders           About GeneDecksing

Genetic Association Database (GAD): DUSP18

Export disorders for DUSP18 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for DUSP18 gene integrated from 9 sources:
(articles sorted by number of sources associating them with DUSP18)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Identification and characterization of two novel low-molecular-weight dual specificity phosphatases. (PubMed id 12408986)1, 2, 3 Hood K.L.... Yoon C. (2002)
  2. Structure of human DSP18, a member of the dual-specificity protein tyrosine phosphatase family. (PubMed id 16699184)1, 2, 9 Jeong D.G....Kim S.J. (2006)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
  5. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
  6. Molecular cloning and characterization of a novel dual-specificity phosphatase18 gene from human fetal brain. (PubMed id 12591617)1, 2 Wu Q.... Mao Y. (2003)
  7. Dual specificity phosphotase 18, interacting with SAPK, dephosphorylates SAPK and inhibits SAPK/JNK signal pathway in vivo. (PubMed id 16720344)1, 9 Wu Q....Mao Y. (2006)
  8. Dual-specificity phosphatases: critical regulators with diverse cellular targets. (PubMed id 19228121)1 Patterson K.I....Daly R.J. (2009)
  9. A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. (PubMed id 17434096)4 Matarin M....Meschia J.F. (2007)
  10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 150290 HGNC: 18484 AceView: DUSP18 Ensembl:ENSG00000167065 euGenes: HUgn150290
ECgene: DUSP18 H-InvDB: DUSP18

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for DUSP18 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for DUSP18 gene:
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