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DUSP15 Gene

protein-coding   GIFtS: 49
GCID: GC20M030446

Dual Specificity Phosphatase 15

(Previous name: dual specificity phosphatase-like 15)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Dual Specificity Phosphatase 151 2     Dual Specificity Protein Phosphatase 152
Dual Specificity Phosphatase-Like 151 2     C20orf573
Vaccinia Virus VH1-Related Dual-Specific Protein Phosphatase Y2 3     EC 3.1.3.163
VHY2 3     EC 3.1.3.483
VH1-Related Member Y2 3     

External Ids:    HGNC: 162361   Entrez Gene: 1288532   Ensembl: ENSG000001495997   UniProtKB: Q9H1R23   

Export aliases for DUSP15 gene to outside databases

Previous GC identifers: GC20M030237 GC20M030183 GC20M031133 GC20M031180 GC20M031181 GC20M029899 GC20M029912 GC20M030437 GC20M030439 GC20M030443


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DUSP15 Gene:
The protein encoded by this gene belongs to the non-receptor class of the protein-tyrosine phosphatase family. The
encoded protein has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity,
and therefore is known as a dual specificity phosphatase. Three transcript variants encoding two different
isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for DUSP15 Gene:
DUSP15 (dual specificity phosphatase 15) is a protein-coding gene. Diseases associated with DUSP15 include vaccinia, and neuronitis. GO annotations related to this gene include protein tyrosine phosphatase activity and protein tyrosine/serine/threonine phosphatase activity. An important paralog of this gene is DUSP26.

Gene Wiki entry for DUSP15 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000020.11  NC_018931.2  NT_011362.11  
Regulatory elements:
   Regulatory transcription factor binding sites in the DUSP15 gene promoter:
         AREB6   Nkx2-5   POU3F2   GATA-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDUSP15 promoter sequence
   Search Chromatin IP Primers for DUSP15

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DUSP15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.21   Ensembl cytogenetic band:  20q11.21   HGNC cytogenetic band: 20q11.21

DUSP15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DUSP15 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M030446:  view genomic region     (about GC identifiers)

Start:
30,435,440 bp from pter      End:
30,458,550 bp from pter
Size:
23,111 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DUS15_HUMAN, Q9H1R2 (See protein sequence)
Recommended Name: Dual specificity protein phosphatase 15  
Size: 295 amino acids; 31882 Da
Caution: Although assigned as two separate genes (c20orf57 and DUSP15), it is probable that C20orf57 does not
exist by itself and is a part of the DUSP15 gene
1 PDB 3D structure from and Proteopedia for DUSP15:
1YZ4 (3D)    
Secondary accessions: A6NH79 A8MVC8 Q5QP62 Q5QP63 Q5QP65 Q6PGN7 Q8N826 Q9BX24
Alternative splicing: 4 isoforms:  Q9H1R2-1   Q9H1R2-2   Q9H1R2-3   Q9H1R2-4   (Initiator Met-1 is removed. Myristoylated on Gly-2)

Explore the universe of human proteins at neXtProt for DUSP15: NX_Q9H1R2

Explore proteomics data for DUSP15 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See DUSP15 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001012662.1  NP_542178.2  NP_817130.1  

    ENSEMBL proteins: 
     ENSP00000397486   ENSP00000278979   ENSP00000419818   ENSP00000381158   ENSP00000365133  
     ENSP00000341658   ENSP00000390355   ENSP00000381157  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DUSPA: Protein tyrosine phosphatases / Class I Cys-based PTPs : Atypical dual specificity phosphatases

    Selected InterPro protein domains (see all 8):
     IPR000387 Tyr/Dual-sp_Pase
     IPR008984 SMAD_FHA_domain
     IPR020422 Dual-sp_phosphatase_subgr_cat
     IPR017855 SMAD_dom-like
     IPR016130 Tyr_Pase_AS

    Graphical View of Domain Structure for InterPro Entry Q9H1R2

    ProtoNet protein and cluster: Q9H1R2

    1 Blocks protein domain: IPB000340 Dual specificity protein phosphatase

    UniProtKB/Swiss-Prot: DUS15_HUMAN, Q9H1R2
    Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily
    Similarity: Contains 1 tyrosine-protein phosphatase domain


    DUSP15 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DUS15_HUMAN, Q9H1R2
    Catalytic activity: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
    Catalytic activity: [a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate

         Enzyme Numbers (IUBMB): EC 3.1.3.161 EC 3.1.3.481

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004725protein tyrosine phosphatase activity IEA--
    GO:0005515protein binding IPI17474147
    GO:0008138protein tyrosine/serine/threonine phosphatase activity IBA--
    GO:0016791phosphatase activity ----
         
    DUSP15 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DUSP15
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    miRNA
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    Block miRNA regulation of human, mouse, rat DUSP15 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DUSP15 (see all 13):
    hsa-miR-3910 hsa-miR-647 hsa-miR-103a hsa-miR-361-3p hsa-miR-214 hsa-miR-1184 hsa-miR-124 hsa-miR-593*
    SwitchGear 3'UTR luciferase reporter plasmidDUSP15 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DUSP15

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    Browse Sino Biological Human cDNA Clones
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DUSP15


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DUS15_HUMAN, Q9H1R2: Cytoplasm (Probable)
    DUS15_HUMAN, Q9H1R2: Isoform 3: Cell membrane; Lipid-anchor; Cytoplasmic side

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005886plasma membrane IEA--

    DUSP15 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DUSP15
    Interactions:

        Search GeneGlobe Interaction Network for DUSP15

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for DUSP15 (Q9H1R21, 2, 3 ENSP000003416584) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PLCG1P191741, 2, 3, ENSP000002440074EBI-1752795,EBI-79387 MINT-8112495 I2D: score=3 STRING: ENSP00000244007
    ABL1P005192, 3, ENSP000003614234MINT-8110287 I2D: score=3 STRING: ENSP00000361423
    PIK3R1P279862, 3, ENSP000002743354MINT-8111907 I2D: score=3 STRING: ENSP00000274335
    NCK1P163331, 3, ENSP000002889864EBI-1752795,EBI-389883 I2D: score=2 STRING: ENSP00000288986
    SRCP129312, 3, ENSP000003509414MINT-8113071 I2D: score=3 STRING: ENSP00000350941
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006470protein dephosphorylation IBA--
    GO:0016311dephosphorylation ----

    DUSP15 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DUSP15 (DUS15)

    3 HMDB Compounds for DUSP15    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    PhosphateNFB Orthophosphate (see all 13)14265-44-2--
    WaterDihydrogen oxide (see all 2)7732-18-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for DUSP15 gene (3 alternative transcripts): 
    NM_001012644.1  NM_080611.3  NM_177991.1  

    Unigene Cluster for DUSP15:

    Dual specificity phosphatase 15
    Hs.585017  [show with all ESTs]
    Unigene Representative Sequence: AK091960
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000447647 ENST00000278979(uc002wwu.1) ENST00000486996 ENST00000398084(uc002www.1)
    ENST00000375966 ENST00000339738(uc002wwx.1) ENST00000459848 ENST00000493115
    ENST00000428829 ENST00000398083(uc002wwv.1)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate DUSP15 (see all 13):
    hsa-miR-3910 hsa-miR-647 hsa-miR-103a hsa-miR-361-3p hsa-miR-214 hsa-miR-1184 hsa-miR-124 hsa-miR-593*
    SwitchGear 3'UTR luciferase reporter plasmidDUSP15 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DUSP15
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    GenScript: all cDNA clones in your preferred vector (see all 3): DUSP15 (NM_177991)
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    Additional mRNA sequence: 

    AK091960.1 BC056911.1 

    6 DOTS entries:

    DT.95270086  DT.443790  DT.95270085  DT.100741390  DT.97792550  DT.99930631 

    Selected AceView cDNA sequences (see all 48):

    AK000652 AI024644 BX114315 BM554314 BF732835 AK091960 NM_177991 CR617339 
    BX280906 AW137822 BI826770 NM_080611 AW338231 BC056911 BI759287 BI829823 
    BI560652 AK097430 BI517878 BI831210 BV187109 AW406620 BI757411 AW593296 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for DUSP15    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                          -           -           -                           
    SP2:                          -           -                                       
    SP3:                                                                              


    ECgene alternative splicing isoforms for DUSP15

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DUSP15 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGTCACCCCA
    DUSP15 Expression
    About this image


    DUSP15 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Testis (Reproductive System)
             Pre-Sertoli Cells Testis Cord
     
     Spinal Cord (Nervous System)
             Oligodendrocyte-like cells
     
     Brain (Nervous System)
             Oligodendrocyte-like cells
     
     Oligodendrocytes (Nervous System)
             Oligodendrocyte-like cells
    DUSP15 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DUSP15 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.585017

    UniProtKB/Swiss-Prot: DUS15_HUMAN, Q9H1R2
    Tissue specificity: Highly expressed in testis

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DUSP15

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for DUSP15 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dusp151 , 5 dual specificity phosphatase-like 151, 5 87.09(n)1
    88.94(a)1
      2 (75.41 cM)5
    2528641  NM_001159376.11  NP_001152848.11 
     1529409975 
    chicken
    (Gallus gallus)
    Aves DUSP151 dual specificity phosphatase 15 69.63(n)
    71.03(a)
      419277  XM_417451.3  XP_417451.1 
    lizard
    (Anolis carolinensis)
    Reptilia DUSP156
    dual specificity phosphatase 15
    70(a)
    1 ↔ 1
    GL343505.1(23203-29289)
    zebrafish
    (Danio rerio)
    Actinopterygii dusp22a6
    dual specificity phosphatase 22a
    45(a)
    many ↔ many
    18(30455508-30508966) ENSDARG00000056396
    fruit fly
    (Drosophila melanogaster)
    Insecta CG100896
    --
    23(a)
    1 → many
    3L(13458909-13467643)
    worm
    (Caenorhabditis elegans)
    Secernentea C16A3.26
    Protein C16A3.2 (C16A3.2) mRNA, complete cds
    22(a)
    1 → many
    III(6389833-6390838) WBGene00015807


    ENSEMBL Gene Tree for DUSP15 (if available)
    TreeFam Gene Tree for DUSP15 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DUSP15 gene
    DUSP262  DUSP212  DUPD12  DUSP32  DUSP132  DUSP272  STYX2  DUSP142  
    DUSP192  DUSP282  DUSP222  DUSP182  
    4 SIMAP similar genes for DUSP15 using alignment to 3 protein entries:     DUS15_HUMAN (see all proteins):
    DUSP22    DUSP19    DUSP18    DUSP21

    DUSP15 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DUSP15 (see all 164)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1432627301,2
    C--30448403(+) TCTGG-/CTGTGT 3 -- ds50010--------
    rs793190471,2
    F--30448465(+) ATTAAG/ATGAAC 3 -- ds50012Minor allele frequency- A:0.06NA EA 122
    rs1426182811,2
    --30448532(+) TTGTGA/CACAGG 3 -- ds50010--------
    rs49115351,2
    C,F,A--30448565(+) GGAGGG/AGCCCC 3 -- ds5001 trp32Minor allele frequency- A:0.15NA EA 240
    rs1846431601,2
    --30448606(+) GAAGGG/TGGTTC 3 -- ds50010--------
    rs1468467241,2
    --30449043(+) TGGGGA/GCGCTG 3 -- ut310--------
    rs125691,2
    C,F,H--30449181(-) CTCCCC/TACTTC 3 -- ut31 ese313Minor allele frequency- T:0.10EA NS NA WA EU 1881
    rs1135057271,2
    C,F--30449183(+) AGTGGA/C/GGAGCC 6 -- ut312CSA EU 251
    rs2004746171,2
    C--30449234(+) GACACC/TGGGGG 6 Q R mis10--------
    rs9473101,2
    C,F,A,H--30449325(+) CTGCAC/GGGTTC 6 L V mis110Minor allele frequency- G:0.43NS EA NA WA CSA 661

    HapMap Linkage Disequilibrium report for DUSP15 (30435440 - 30458550 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DUSP15:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv912836CNV Loss21882294
    nsv833952CNV Gain17160897

    Human Gene Mutation Database (HGMD): DUSP15
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DUSP15
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for DUSP15:    
    About MalaCards
    vaccinia    neuronitis


    DUSP15 for disorders           About GeneDecksing


    Export disorders for DUSP15 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DUSP15 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with DUSP15)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX. (PubMed id 15138252)1, 2, 3 Alonso A.... Mustelin T. (J. Biol. Chem. 2004)
    2. Crystal structure of the catalytic domain of human VHY, a dual- specificity protein phosphatase. (PubMed id 16170801)1, 2 Yoon T.-S.... Kim S.J. (Proteins 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    6. Identification of VHY/Dusp15 as a regulator of oligodendrocyte differentiation through a systematic genomics approach. (PubMed id 22792334)1 Schmidt F....Hooft van Huijsduijnen R. (PLoS ONE 2012)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    10. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (Proteomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 128853 HGNC: 16236 AceView: DUSP15 Ensembl:ENSG00000149599 euGenes: HUgn128853
    ECgene: DUSP15 H-InvDB: DUSP15

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DUSP15 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DUSP15 gene:
    Search GeneIP for patents involving DUSP15

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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