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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DUSP12 Gene

protein-coding   GIFtS: 55
GCID: GC01P161719

dual specificity phosphatase 12

 Explore 2 diseases affiliated with
DUSP12 via our new
 Human Malady Compendium 
Biological research products
for DUSP12
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Dual Specificity Phosphatase 121 2     Serine/Threonine Specific Protein Phosphatase2
DUSP11 2 5     YVH1 Protein-Tyrosine Phosphatase Ortholog2
YVH11 2 5     EC 3.1.3.163
Dual Specificity Tyrosine Phosphatase YVH12 3     EC 3.1.3.483
Dual Specificity Protein Phosphatase 122     

External Ids:    HGNC: 30671   Entrez Gene: 112662   Ensembl: ENSG000000817217   OMIM: 6048355   UniProtKB: Q9UNI63   

Export aliases for DUSP12 gene to outside databases

Previous GC identifers: GC01P159354 GC01P157370 GC01P158415 GC01P158906 GC01P158451 GC01P159989 GC01P132964


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DUSP12:
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases
inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.
They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38),
which is associated with cellular proliferation and differentiation. Different members of the family of dual
specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution
and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This
gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized
predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. (provided by
RefSeq, Jul 2008)

Gene Wiki entry for DUSP12


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DUSP12 gene promoter:
         STAT1   AML1a   STAT4   STAT1beta   STAT1alpha   CREB   deltaCREB   STAT2   STAT3   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDUSP12 promoter sequence
   Search SABiosciences Chromatin IP Primers for DUSP12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DUSP12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21-q22   Ensembl cytogenetic band:  1q23.3   HGNC cytogenetic band: 1q21-q22

DUSP12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DUSP12 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P161719:  view genomic region     (about GC identifiers)

Start:
161,719,548 bp from pter      End:
161,727,028 bp from pter
Size:
7,481 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DUS12_HUMAN, Q9UNI6 (See protein sequence)
Recommended Name: Dual specificity protein phosphatase 12  
Size: 340 amino acids; 37687 Da
Cofactor: Binds 2 zinc ions per subunit
Subcellular location: Nucleus
Secondary accessions: Q5VXA8

Explore the universe of human proteins at neXtProt for DUSP12: NX_Q9UNI6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UNI6

  • DUSP12 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_009171.1  
    ENSEMBL proteins: 
     ENSP00000356920  

    Human Recombinant Protein Products: 
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    Uscn Proteins for DUSP12

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IBA--


    DUSP12 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for DUSP12


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DUSP12 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR000387 Tyr/Dual-sp_Pase
     IPR020422 Dual-sp_phosphatase_subgr_cat
     IPR024950 DUSP
     IPR000340 Dual-sp_phosphatase_cat-dom
     IPR016278 DUSP12

    Graphical View of Domain Structure for InterPro Entry Q9UNI6

    ProtoNet protein and cluster: Q9UNI6

    1 Blocks protein family: IPB000340 Dual specificity protein phosphatase

    UniProtKB/Swiss-Prot: DUS12_HUMAN, Q9UNI6
    Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily
    Similarity: Contains 1 tyrosine-protein phosphatase domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: DUS12_HUMAN, Q9UNI6
    Catalytic activity: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
    Catalytic activity: A phosphoprotein + H(2)O = a protein + phosphate

         Genatlas biochemistry entry for DUSP12:
    dual specificity phosphatase 12

    Enzyme Numbers (IUBMB): EC 3.1.3.161 EC 3.1.3.481

    miRNA
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    hsa-let-7b (MIRT001636)

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    1 QIAGEN miScript miRNA Assays for microRNA that regulate DUSP12:
    hsa-miR-889
    SwitchGear 3'UTR luciferase reporter plasmidDUSP12 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004721phosphoprotein phosphatase activity ----
    GO:0004725protein tyrosine phosphatase activity IEA--
    GO:0008138protein tyrosine/serine/threonine phosphatase activity IBA--
    GO:0008270zinc ion binding IEA--
    GO:0019900kinase binding IEA--


    DUSP12 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for DUSP12:
     Decreased focal adhesion (FA)   Increased apoptosis 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DUSP12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    5/40 Interacting proteins for DUSP12 (Q9UNI62, 3 ENSP000003569204) via UniProtKB, MINT, STRING, and/or I2D (see all 40)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MBD6Q96DN62, 3, ENSP000003478964MINT-65783 I2D: score=5 STRING: ENSP00000347896
    KIAA1377Q9P2H02, 3MINT-65784 I2D: score=5 
    PTNP212462, 3MINT-65782 I2D: score=5 
    RABAC1Q9UI142, 3, ENSP000002220084MINT-67416 I2D: score=5 STRING: ENSP00000222008
    NR1H2P550552, 3, ENSP000002537274MINT-8254567 I2D: score=2 STRING: ENSP00000253727
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006464cellular protein modification process TAS10446167
    GO:0006470protein dephosphorylation IBA--
    GO:0007254NOT JNK cascade IRD--
    GO:0033133positive regulation of glucokinase activity IBA--
    GO:0035335peptidyl-tyrosine dephosphorylation TAS10446167


    DUSP12 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DUSP12

    3 HMDB Compounds for DUSP12    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    PhosphateNFB Orthophosphate (see all 13)14265-44-2--
    WaterDihydrogen oxide (see all 2)7732-18-5--
    Search CenterWatch for drugs/clinical trials and news about DUSP12 / DUS12 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DUSP12 gene: 
    NM_007240.1  

    Unigene Cluster for DUSP12:

    Dual specificity phosphatase 12
    Hs.416216  [show with all ESTs]
    Unigene Representative Sequence: BC006286
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000484291 ENST00000367943(uc001gbo.3) ENST00000464004 ENST00000490591
    ENST00000463365

    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate DUSP12:
    hsa-miR-889
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    Inhib. RNA
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    Additional cDNA sequence: 

    AF119226.1 AK000259.1 BC006286.1 BT006633.1 

    6 DOTS entries:

    DT.86839113  DT.441722  DT.91743497  DT.100678121  DT.100779348  DT.100839118 

    24/161 AceView cDNA sequences (see all 161):

    CR599391 BQ423889 CB146889 AK000259 BM714291 CB852566 AL047655 AA374202 
    CB159708 AA031672 AA927984 CB240728 BM709742 AA464391 BM474343 BU622998 
    BU731552 BI712932 BM782644 CR611136 CA776245 BM807904 AA485951 AA147450 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for DUSP12    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b
    SP1:                                      -     -                                       
    SP2:                                      -                                             
    SP3:                                -     -                                             
    SP4:                                      -     -     -                                 
    SP5:                                -                                                   


    ECgene alternative splicing isoforms for DUSP12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DUSP12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TACATTTTAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See DUSP12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DUSP12

    SOURCE GeneReport for Unigene cluster: Hs.416216

    UniProtKB/Swiss-Prot: DUS12_HUMAN, Q9UNI6
    Tissue specificity: Ubiquitous, highest expression in spleen, testis, ovary, and peripheral blood leukocytes and lower
    expression in liver and lung

        SABiosciences Expression via Pathway-Focused PCR Array including DUSP12: 
              Protein Phosphatases in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DUSP12 gene from 10/31 species (see all 31)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dusp121 , 5 dual specificity phosphatase 121, 5 82.1(n)1
    83.78(a)1
      1 (77.27 cM)5
    809151  NM_023173.21  NP_075662.21 
     1708734985 
    chicken
    (Gallus gallus)
    Aves DUSP121 dual specificity phosphatase 12 64.5(n)
    63.31(a)
      425349  XM_423122.3  XP_423122.2 
    lizard
    (Anolis carolinensis)
    Reptilia DUSP126
    --
    59(a)
    1 ↔ 1
    GL343218.1(938802-946962)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.162072 Xenopus laevis transcribed sequence with weak similarity more 79.57(n)    BJ098033.1 
    zebrafish
    (Danio rerio)
    Actinopterygii dusp121 dual specificity phosphatase 12 61.15(n)
    61.49(a)
      573998  NM_001025177.1  NP_001020348.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta MKP-41 MAPK Phosphatase 4 45.17(n)
    38.28(a)
      32963  NM_134488.2  NP_608332.2 
    worm
    (Caenorhabditis elegans)
    Secernentea C24F3.26
    Protein C24F3.2
    28(a)
    1 ↔ 1
    IV(10222489-10223729)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YVH1(YIR026C)4
    YVH11
    Protein phosphatase involved in vegetative growth at more4
    Yvh1p1
    43.96(n)1
    34.22(a)1
      9(405967-404873)4
    8548441, 4  NP_012292.31  NP_012292.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G185931 dual specificity protein phosphatase-like protein 49.85(n)
    46.02(a)
      827592  NM_117974.2  NP_567561.1 
    rice
    (Oryza sativa)
    Liliopsida Os12g01337001 hypothetical protein 50.91(n)
    42.58(a)
      4351431  NM_001072622.1  NP_001066090.1 


    ENSEMBL Gene Tree for DUSP12 (if available)
    TreeFam Gene Tree for DUSP12 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DUSP12 gene
    DUSP152  DUSP222  STYX2  

    DUSP12 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for DUSP12
    PGOHUM00000237695


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/15 NCBI SNPs in DUSP12 are shown (see all 15    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1871697001,2
    --161720679(+) CACAGC/TACTCC 1 -- int10--------
    rs354398331,2
    C,--161722779(+) GTCTCAAA/-AAAAA 1 -- int11Minor allele frequency- -:0.00CSA 2
    rs1379347061,2
    --161726274(+) AAAGC-/TATATATA
    TATATATATA
    TATAT
    1 -- int10--------
    rs1478652941,2
    C,--161726274(+) AAAGC-/TATATAT
    ATATATATA
    TATAT
    1 -- int10--------
    rs105278141,2
    C--161726279(+) tatat-/ATATATA
    TATATATAT
    GCCAC
    1 -- int11Minor allele frequency- ATATATATATATATAT:0.00NA 2
    rs720489281,2
    ----161726277(+) TATAT-/ATATAT
            
    ATATA
    1 -- int10--------
    rs725105341,2
    ----161717877(+) CCCTC-/CTTGCTG 1 -- us2k10--------
    rs724688031,2
    ----161726277(+) TATAT-/ATAT  
            
    ATATA
    1 -- int10--------
    rs598992271,2
    ----161726279(+) TATAT-/ATA   
       TATAT
    GCCAC
    1 -- int10--------
    rs2002882571,2
    ----161726274(+) AAAGC-/TATATA
    TATATATA
    TATAT
    1 -- int10--------

    HapMap Linkage Disequilibrium report for DUSP12 (161719548 - 161727028 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for DUSP12
         1 CNV: 6791

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DUSP12 for disorders           About GeneDecksing

    OMIM gene information: 604835    OMIM disorders: --

    2 diseases for DUSP12:    About MalaCards
    sarcoma    malaria

    Human Genome Epidemiology (HuGE) Navigator: DUSP12 (4 documents)

    Export disorders for DUSP12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DUSP12 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with DUSP12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of the human YVH1 protein-tyrosine phosphatase orthologue reveals a novel zinc binding domain essential for in vivo function. (PubMed id 10446167)1, 2, 3, 9 Muda M.... Dixon J.E. (1999)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. [Association of -6735T-->C variant of glucokinase-associated dual-specificity phosphatase 12 gene with type 2 diabetes in Chinese] (PubMed id 19087671)1, 9 Gao F....Xiang K.S. (2008)
    5. Polymorphisms in the glucokinase-associated, dual-specificity phosphatase 12 (DUSP12) gene under chromosome 1q21 linkage peak are associated with type 2 diabetes. (PubMed id 16936214)1, 9 Das S.K....Elbein S.C. (2006)
    6. Type 2 diabetes susceptibility genes on chromosome 1q21-24. (PubMed id 18269685)1, 9 Hasstedt S.J....Elbein S.C. (2008)
    7. Lack of association between genetic polymorphisms wit hin DUSP12 - ATF6 locus and glucose metabolism related traits in a Chinese popu lation. (PubMed id 21211013)1 Hu C....Jia W. (2011)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. The dual-specificity phosphatase hYVH1 (DUSP12) is a novel modulator of cellular DNA content. (PubMed id 21521943)1 Kozarova A....Vacratsis P.O. (2011)
    10. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 11266 HGNC: 3067 AceView: DUSP12 Ensembl:ENSG00000081721 euGenes: HUgn11266
    ECgene: DUSP12 H-InvDB: DUSP12

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DUSP12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DUSP12 gene:
    Search GeneIP for patents involving DUSP12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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