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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DUS4L Gene

protein-coding GIFtS: 52
GCID: GC07P107203

dihydrouridine synthase 4-like (S. cerevisiae)

Explore 5 diseases affiliated with
DUS4L via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Dihydrouridine Synthase 4-Like (S. Cerevisiae)¹ ²		TRNA-Dihydrouridine(20a/20b) Synthase [NAD(P)+]-Like²
DUS4¹ ²		EC 1.3.1.-³
PP35¹ ²		Pp35¹
Protein Similar To E.Coli Yhdg And R. Capsulatus NifR3²		TRNA-Dihydrouridine Synthase 4-Like³

External Ids:	HGNC: 21517¹	Entrez Gene: 11062²	Ensembl: ENSG00000105865⁷	UniProtKB: O95620³

Export aliases for DUS4L gene to outside databases

Previous GC identifers: GC07P106799 GC07P106991 GC07P101565

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: DUS4L_HUMAN, O95620

Function: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DUS4L gene promoter:
Nkx3-1 Nkx3-1 v4 AML1a NCX/Ncx Nkx3-1 v1 Tal-1beta Gfi-1 E47 Nkx3-1 v2 Nkx3-1 v3
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DUS4L promoter sequence

Search SABiosciences Chromatin IP Primers for DUS4L

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DUS4L

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22-q31 Ensembl cytogenetic band: 7q22.3 HGNC cytogenetic band: 7q22-q31

DUS4L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DUS4L gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07P107203: view genomic region (about GC identifiers)

Start:	107,203,929 bp from pter	End:	107,218,968 bp from pter
Size:	15,040 bases	Orientation:	plus strand

1 alternative location:

Chr7+,CRA_TCAG 106,565,521-106,580,056

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DUS4L_HUMAN, O95620 (See protein sequence)

Recommended Name: tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like

Size: 317 amino acids; 35816 Da

Cofactor: FAD (By similarity)

Sequence caution: Sequence=AAD00100.1; Type=Frameshift; Positions=14;

Secondary accessions: B4DLX0 Q2NKK1

Alternative splicing: 2 isoforms: O95620-1 O95620-2 (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for DUS4L: NX_O95620

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O95620

DUS4L Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001257348.1 NP_853559.1

ENSEMBL proteins:

ENSP00000402887 ENSP00000265720 ENSP00000388904 ENSP00000388061 ENSP00000412739

ENSP00000399375 ENSP00000385274

Human Recombinant Protein Products:

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	Uscn Proteins for DUS4L

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	Uscn Antibodies for DUS4L
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Assay Products for DUS4L:

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	Uscn ELISAs and CLIAs for DUS4L

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

DUS4L for domains About GeneDecksing

3 InterPro domains/families:

IPR013785 Aldolase_TIM

IPR001269 tRNA_hU_synthase

IPR018517 tRNA_hU_synthase_CS

Graphical View of Domain Structure for InterPro Entry O95620

ProtoNet protein and cluster: O95620

1 Blocks protein family: IPB001269 Protein of unknown function UPF0034

UniProtKB/Swiss-Prot: DUS4L_HUMAN, O95620

Similarity: Belongs to the dus family. Dus4 subfamily

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: DUS4L_HUMAN, O95620

Function: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)

Enzyme Number (IUBMB): EC 1.3.1.-¹

miRNA Products:		OriGene 3'-UTR Clone: DUS4L Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DUS4L
		7 QIAGEN miScript miRNA Assays for microRNAs that regulate DUS4L:
		hsa-miR-3671 hsa-miR-607 hsa-miR-548d-3p hsa-miR-548am hsa-miR-548x hsa-miR-3148 hsa-miR-3921
		SwitchGear 3'UTR luciferase reporter plasmid: DUS4L 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DUS4L (see all 6) Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DUS4L

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for DUS4L

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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DUS4L (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DUS4L OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: DUS4L (NM_181581)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DUS4L
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DUS4L

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for DUS4L
		Search LifeMap BioReagents cell lines for DUS4L

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DUS4L

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0017150	tRNA dihydrouridine synthase activity	IEA	--
GO:0050660	flavin adenine dinucleotide binding	IEA	--

DUS4L for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for DUS4L:

Downregulation of NF-kappaB pa

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DUS4L

STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

5/11 Interacting proteins for DUS4L (O95620³ ENSP00000265720⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 11)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
FANCA	O15360³, ENSP00000373952⁴	I2D: score=1 STRING: ENSP00000373952
METTL1	Q9UBP6³, ENSP00000314441⁴	I2D: score=1 STRING: ENSP00000314441
TOP1	P11387³, ENSP00000354522⁴	I2D: score=1 STRING: ENSP00000354522
BYSL	Q13895³	I2D: score=1
CCT6A	P40227³	I2D: score=1

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008033	tRNA processing	--	--

DUS4L for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DUS4L

2 HMDB Compounds for DUS4L About this table

Compound	Synonyms	CAS #	PubMed Ids
5,6-Dihydrouridine	5,6-Dihydrouridine (see all 4)	5627-05-4	--
FAD	1H-Purin-6-amine flavin dinucleotide (see all 21)	146-14-5	--

Search CenterWatch for drugs/clinical trials and news about DUS4L

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DUS4L gene (2 alternative transcripts):

NM_001270419.1 NM_181581.2

Unigene Cluster for DUS4L:

Dihydrouridine synthase 4-like (S. cerevisiae)

Hs.97627 [show with all ESTs]

Unigene Representative Sequence: NR_073002

12 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000498786 ENST00000422290 ENST00000265720(uc003veh.3 uc011klw.2 uc011klx.2 uc010ljl.3)

ENST00000431839 ENST00000443233 ENST00000436411(uc022ajw.1) ENST00000458611

ENST00000467916 ENST00000471763 ENST00000497798 ENST00000485825 ENST00000402620

miRNA Products:		OriGene 3'-UTR Clone: DUS4L Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DUS4L
		7 QIAGEN miScript miRNA Assays for microRNAs that regulate DUS4L:
		hsa-miR-3671 hsa-miR-607 hsa-miR-548d-3p hsa-miR-548am hsa-miR-548x hsa-miR-3148 hsa-miR-3921
		SwitchGear 3'UTR luciferase reporter plasmid: DUS4L 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DUS4L (see all 6) Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DUS4L

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DUS4L (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DUS4L OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: DUS4L (NM_181581)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DUS4L
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DUS4L

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DUS4L

Additional cDNA sequence:

AK294095.1 AK297195.1 AK308472.1 NR_073002.1 NR_073003.1 NR_073004.1 NR_073005.1 U62767.1

12 DOTS entries:

DT.110148 DT.121102930 DT.100877360 DT.121103182 DT.100877354 DT.40119094 DT.91748830 DT.100667358

DT.100723879 DT.102836929 DT.70102487 DT.91706089

24/72 AceView cDNA sequences (see all 72):

CR605496 AV718761 NM_181581 BQ771928 AI609138 AI275853 CA428914 AW163754

BG250736 AI378669 BU621752 AV714249 AW157722 BX504337 CR602101 CR625341

AL523141 BX356318 CB851456 H59368 H51774 BU685851 BP375403 AI679397

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for DUS4L (see all 9) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	·	1f	^	2	^	3a	·	3b	·	3c	^	4	^	5	^	6a	·	6b	^	7a	·	7b	·	7c	^	8a	·	8b	·	8c	^	9a	·	9b
SP1:									-		-								-		-						-		-
SP2:											-								-								-		-
SP3:											-								-		-				-		-		-
SP4:																			-		-				-		-		-
SP5:											-

ECgene alternative splicing isoforms for DUS4L

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DUS4L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CACTGCAAGA

About this image

DUS4L expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Limb

Forelimb Myotome

Limb Muscle Progenitor Cells

Skeletal Muscle

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See DUS4L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DUS4L

SOURCE GeneReport for Unigene cluster: Hs.97627

SABiosciences Custom PCR Arrays for DUS4L

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DUS4L Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DUS4L

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DUS4L

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the last universal common ancestor (LUCA).

Orthologs for DUS4L gene from 10/36 species (see all 36) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	DUS4L¹	dihydrouridine synthase 4-like (S. cerevisiae)	75.45(n) 76.19(a)		769352 XM_001231914.2 XP_001231915.1
lizard (Anolis carolinensis)	Reptilia	DUS4L⁶	--	74(a)	1 ↔ 1	5(97612290-97622050)
African clawed frog (Xenopus laevis)	Amphibia	BU913916.1²	--	76.91(n)		BU913916.1
zebrafish (Danio rerio)	Actinopterygii	dus4l¹	dihydrouridine synthase 4-like (S. cerevisiae)	69.14(n) 71.73(a)		445096 NM_001003490.1 NP_001003490.1
fruit fly (Drosophila melanogaster)	Insecta	CG10495¹	CG10495	49.45(n) 45.07(a)		35179 NM_136095.2 NP_609939.1
worm (Caenorhabditis elegans)	Secernentea	C45G9.2¹	Protein C45G9.2	54.17(n) 49.29(a)		183479 NM_065677.5 NP_498078.2
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	DUS4(YLR405W)⁴ DUS4¹	Dihydrouridine synthase, member of a widespread family more⁴ Dus4p¹	50.59(n)¹ 44.72(a)¹		12(929789-930892)⁴ 851121^{1, 4} NP_013509.1^{1, 4}
thale cress (Arabidopsis thaliana)	eudicotyledons	AT5G47970⁶ AT3G63510⁶	FMN-linked oxidoreductase-like protein protein	13(a) 13(a)	possible ortholog possible ortholog	5(19422203-19425811) 3(23450536-23452794)
rice (Oryza sativa)	Liliopsida	--	tRNA-dihydrouridine synthase, putative, expressed	12(a)	possible ortholog	4(11791875-11805701)
E. coli (Escherichia coli)	Gamma proteobacteria	dusC⁶ dusA⁶	tRNA-dihydrouridine synthase A	21(a) 18(a)	possible ortholog possible ortholog	Chromosome(2227460-2228407) Chromosome(4259737-4260729)

ENSEMBL Gene Tree for DUS4L (if available)
TreeFam Gene Tree for DUS4L (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs116431555^1,2	C,F,	--	101579671(+)	`AACTCG/ACTGTT`	1	--	us2k¹		1		WA	118
rs10273085^1,2	C,H,	--	107207090(+)	`AACTTT/ACCTGA`	6	--	int¹		4		NS EA	404
rs192210816^1,2		--	107207094(+)	`TTCCTA/GAATAA`	6	--	int¹		0	--	--	--	--
rs77731794^1,2		--	107207227(+)	`ACATGC/GTAAAC`	6	--	int¹		0	--	--	--	--
rs5886419^1,2	C	--	107207238(+)	`AAAAA-/ATCTCG`	6	--	int¹ trp³		0	--	--	--	--
rs115583220^1,2	F,	--	107207253(+)	`AATCTC/TGTTTT`	6	--	int¹		1		WA	118
rs142148175^1,2		--	107207300(+)	`TTCCAC/TATCTA`	6	--	int¹		0	--	--	--	--
rs117325889^1,2	F,	--	107207410(+)	`AAATAT/CATGTT`	6	--	int¹		1		NA	120
rs201466996^1,2		--	107207539(+)	`CAAACA/GACAAT`	8	T	syn¹		0	--	--	--	--
rs199510674^1,2	F	--	107207597(+)	`AGCTGG/ATAAAA`	8	/I /V	mis¹		1		EU	1321

HapMap Linkage Disequilibrium report for DUS4L (107203929 - 107218968 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for DUS4L
2 CNVs: 94794 82142

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DUS4L

DNA2.0 Custom Variant and Variant Library Synthesis for DUS4L

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DUS4L for disorders About GeneDecksing

5 diseases for DUS4L: About MalaCards

fanconi's anemia hepatitis b anemia osteoarthritis

hepatitis

Human Genome Epidemiology (HuGE) Navigator: DUS4L (2 documents)

Export disorders for DUS4L gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DUS4L gene integrated from 9 sources:
(articles sorted by number of sources associating them with DUS4L)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)¹ Davila S....Seielstad M. (2010)
Meta-analysis of genome-wide association studies conf irms a susceptibility locus for knee osteoarthritis on chromosome 7q22. (PubMed id 21068099)¹ Evangelou E....Spector T.D. (2010)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)² Ota T.... Sugano S. (2004)
Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)¹ Scherer S.W.... Tsui L.-C. (2003)
Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport. (PubMed id 14499622)¹ Reuter T.Y....Huber P.A. (2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)
Generation and analysis of 280,000 human expressed sequence tags. (PubMed id 8889549)¹ Hillier L.D....Marra M. (1996)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 11062	HGNC: 21517	AceView: PP35	Ensembl:ENSG00000105865	euGenes: HUgn11062
ECgene: DUS4L	H-InvDB: DUS4L

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DUS4L	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DUS4L gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for DUS4L gene:
Search GeneIP for patents involving DUS4L

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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DUS4L Gene

dihydrouridine synthase 4-like (S. cerevisiae)

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DUS4L Gene

dihydrouridine synthase 4-like (S. cerevisiae)

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