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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DUS4L Gene

protein-coding   GIFtS: 54
GCID: GC07P107203

Dihydrouridine Synthase 4-Like (S. Cerevisiae)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Dihydrouridine Synthase 4-Like (S. Cerevisiae)1 2     TRNA-Dihydrouridine(20a/20b) Synthase [NAD(P)+]-Like2
Protein Similar To E.Coli Yhdg And R. Capsulatus NifR31 2     EC 1.3.1.-3
DUS42     pp353
PP352     TRNA-Dihydrouridine Synthase 4-Like3

External Ids:    HGNC: 215171   Entrez Gene: 110622   Ensembl: ENSG000001058657   UniProtKB: O956203   

Export aliases for DUS4L gene to outside databases

Previous GC identifers: GC07P106799 GC07P106991 GC07P101565


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for DUS4L Gene: 
DUS4L (dihydrouridine synthase 4-like (S. cerevisiae)) is a protein-coding gene. Diseases associated with DUS4L include fanconi's anemia, and osteoarthritis. GO annotations related to this gene include tRNA dihydrouridine synthase activity and flavin adenine dinucleotide binding.

UniProtKB/Swiss-Prot: DUS4L_HUMAN, O95620
Function: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NC_018918.2  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DUS4L gene promoter:
         Nkx3-1   Nkx3-1 v4   AML1a   NCX/Ncx   Nkx3-1 v1   Tal-1beta   Gfi-1   E47   Nkx3-1 v2   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DUS4L promoter sequence
   Search SABiosciences Chromatin IP Primers for DUS4L

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DUS4L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22-q31   Ensembl cytogenetic band:  7q22.3   HGNC cytogenetic band: 7q22-q31

DUS4L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DUS4L gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P107203:  view genomic region     (about GC identifiers)

Start:
107,203,929 bp from pter      End:
107,218,968 bp from pter
Size:
15,040 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 106,565,521-106,580,056     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DUS4L_HUMAN, O95620 (See protein sequence)
Recommended Name: tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like  
Size: 317 amino acids; 35816 Da
Cofactor: FAD (By similarity)
Sequence caution: Sequence=AAD00100.1; Type=Frameshift; Positions=14;
Secondary accessions: B4DLX0 Q2NKK1
Alternative splicing: 2 isoforms:  O95620-1   O95620-2   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for DUS4L: NX_O95620

Explore proteomics data for DUS4L at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O95620

  • DUS4L Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DUS4L Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001257348.1  NP_853559.1  

    ENSEMBL proteins: 
     ENSP00000402887   ENSP00000265720   ENSP00000388904   ENSP00000388061   ENSP00000412739  
     ENSP00000399375   ENSP00000385274  

    Human Recombinant Protein Products for DUS4L: 
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    Novus Biologicals DUS4L Protein
    Novus Biologicals DUS4L Lysate
    Browse Sino Biological Recombinant Proteins
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DUS4L 


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    Cloud-Clone Corp. ELISAs for DUS4L 
    Cloud-Clone Corp. CLIAs for DUS4L


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR013785 Aldolase_TIM
     IPR001269 tRNA_hU_synthase
     IPR018517 tRNA_hU_synthase_CS

    Graphical View of Domain Structure for InterPro Entry O95620

    ProtoNet protein and cluster: O95620

    1 Blocks protein domain: IPB001269 Protein of unknown function UPF0034

    UniProtKB/Swiss-Prot: DUS4L_HUMAN, O95620
    Similarity: Belongs to the dus family. Dus4 subfamily


    DUS4L for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DUS4L_HUMAN, O95620
    Function: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By
    similarity)

         Enzyme Number (IUBMB): EC 1.3.1.-1

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010181FMN binding ----
    GO:0016491oxidoreductase activity ----
    GO:0017150tRNA dihydrouridine synthase activity IEA--
    GO:0050660flavin adenine dinucleotide binding IEA--
         
    DUS4L for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for DUS4L:
     Downregulation of NF-kappaB pa  Downregulation of NF-kappaB pa 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for DUS4L 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DUS4L

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DUS4L 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DUS4L 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DUS4L
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate DUS4L:
    hsa-miR-3671 hsa-miR-607 hsa-miR-548d-3p hsa-miR-548am hsa-miR-548x hsa-miR-3148 hsa-miR-3921
    SwitchGear 3'UTR luciferase reporter plasmidDUS4L 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DUS4L


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DUS4L

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/11 Interacting proteins for DUS4L (O956203 ENSP000002657204) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FANCAO153603, ENSP000003739524I2D: score=1 STRING: ENSP00000373952
    METTL1Q9UBP63, ENSP000003144414I2D: score=1 STRING: ENSP00000314441
    TOP1P113873, ENSP000003545224I2D: score=1 STRING: ENSP00000354522
    BYSLQ138953I2D: score=1 
    CCT6AP402273I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000105histidine biosynthetic process ----
    GO:0008033tRNA processing ----
    GO:0055114oxidation-reduction process ----

    DUS4L for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DUS4L

    2 HMDB Compounds for DUS4L    About this table
    CompoundSynonyms CAS #PubMed Ids
    5,6-Dihydrouridine5,6-Dihydrouridine (see all 4)5627-05-4--
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--

    Search CenterWatch for drugs/clinical trials and news about DUS4L

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DUS4L gene (2 alternative transcripts): 
    NM_001270419.1  NM_181581.2  

    Unigene Cluster for DUS4L:

    Dihydrouridine synthase 4-like (S. cerevisiae)
    Hs.97627  [show with all ESTs]
    Unigene Representative Sequence: NR_073002
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000498786 ENST00000422290 ENST00000265720(uc003veh.3 uc011klw.2 uc011klx.2 uc010ljl.3)
    ENST00000431839 ENST00000443233 ENST00000436411(uc022ajw.1) ENST00000458611
    ENST00000467916 ENST00000471763 ENST00000497798 ENST00000485825 ENST00000402620

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DUS4L
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate DUS4L:
    hsa-miR-3671 hsa-miR-607 hsa-miR-548d-3p hsa-miR-548am hsa-miR-548x hsa-miR-3148 hsa-miR-3921
    SwitchGear 3'UTR luciferase reporter plasmidDUS4L 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for DUS4L
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DUS4L
    Clone
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    OriGene clones in human, mouse for DUS4L (see all 7)
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    GenScript: all cDNA clones in your preferred vector: DUS4L (NM_181581)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DUS4L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DUS4L
    Sirion Biotech Customized lentivirus for stable overexpression of DUS4L 
                         Customized lentivirus expression plasmids for stable overexpression of DUS4L 
    Primer
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    OriGene qPCR primer pairs and template standards for DUS4L
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DUS4L
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DUS4L

    Additional mRNA sequence: 

    AK294095.1 AK297195.1 AK308472.1 NR_073002.1 NR_073003.1 NR_073004.1 NR_073005.1 U62767.1 

    12 DOTS entries:

    DT.110148  DT.121102930  DT.100877360  DT.121103182  DT.100877354  DT.40119094  DT.91748830  DT.100667358 
    DT.100723879  DT.102836929  DT.70102487  DT.91706089 

    24/72 AceView cDNA sequences (see all 72):

    CA428914 BG250736 CR602101 AL523141 CR605496 AV718761 CR625341 AV714249 
    BU621752 AW163754 NM_181581 AI275853 BQ771928 BX504337 AW157722 AI609138 
    AI378669 H59368 BX373302 AI522040 AI679904 BE792219 AA626570 AK127802 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for DUS4L (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b · 8c ^ 9a · 9b
    SP1:                          -     -                       -     -                 -     -                                             
    SP2:                                -                       -                       -     -                                             
    SP3:                                -                       -     -           -     -     -                                             
    SP4:                                                        -     -           -     -     -                                             
    SP5:                                -                                                                                                   


    ECgene alternative splicing isoforms for DUS4L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DUS4L expression in normal human tissues (normalized intensities)      DUS4L embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACTGCAAGA
    DUS4L Expression
    About this image


    DUS4L expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Limb (Muscoskeletal System)
             Limb Muscle Progenitor Cells Forelimb Myotome
     
     Skeletal Muscle (Muscoskeletal System)
             Limb Muscle Progenitor Cells Forelimb Myotome

    See DUS4L Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DUS4L

    SOURCE GeneReport for Unigene cluster: Hs.97627
        SABiosciences Custom PCR Arrays for DUS4L
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DUS4L
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DUS4L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for DUS4L gene from 8/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dus4l1 , 5 dihydrouridine synthase 4-like (S. cerevisiae)1, 5 88.61(n)1
    90.51(a)1
      12 (13.68 cM)5
    719161  NM_028002.21  NP_082278.11 
     316400555 
    chicken
    (Gallus gallus)
    Aves DUS4L1 dihydrouridine synthase 4-like (S. cerevisiae) 75.45(n)
    76.19(a)
      769352  XM_001231914.2  XP_001231915.1 
    lizard
    (Anolis carolinensis)
    Reptilia DUS4L6
    tRNA-dihydrouridine synthase
    74(a)
    1 ↔ 1
    5(97612290-97622050)
    African clawed frog
    (Xenopus laevis)
    Amphibia BU913916.12   -- 76.91(n)    BU913916.1 
    zebrafish
    (Danio rerio)
    Actinopterygii dus4l1 dihydrouridine synthase 4-like (S. cerevisiae) 69.14(n)
    71.73(a)
      445096  NM_001003490.1  NP_001003490.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG104951 CG10495 49.45(n)
    45.07(a)
      35179  NM_136095.2  NP_609939.1 
    worm
    (Caenorhabditis elegans)
    Secernentea C45G9.21 Protein C45G9.2 54.17(n)
    49.29(a)
      183479  NM_065677.5  NP_498078.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DUS4(YLR405W)4
    DUS41
    Dihydrouridine synthase, member of a widespread family more4
    Dus4p1
    50.59(n)1
    44.72(a)1
      12(929789-930892)4
    8511211, 4  NP_013509.11, 4 


    ENSEMBL Gene Tree for DUS4L (if available)
    TreeFam Gene Tree for DUS4L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DUS4L gene
    2 SIMAP similar genes for DUS4L using alignment to 4 protein entries:     DUS4L_HUMAN (see all proteins):
    PP35    DUS1L

    DUS4L for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/210 SNPs in DUS4L are shown (see all 210)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs102730851,2
    C,F,H--107207090(+) AACTTT/ACCTGA 6 -- int14Minor allele frequency- A:0.00NS EA 404
    rs1922108161,2
    --107207094(+) TTCCTA/GAATAA 6 -- int10--------
    rs777317941,2
    --107207227(+) ACATGC/GTAAAC 6 -- int10--------
    rs58864191,2
    C--107207237(+) AAAAA-/ATCTCG 6 -- int1 trp30--------
    rs1155832201,2
    F--107207253(+) AATCTC/TGTTTT 6 -- int11Minor allele frequency- T:0.05WA 118
    rs1421481751,2
    --107207300(+) TTCCAC/TATCTA 6 -- int10--------
    rs1173258891,2
    C,F--107207410(+) AAATAT/CATGTT 6 -- int11Minor allele frequency- C:0.03NA 120
    rs2014669961,2
    C--107207539(+) CAAACA/GACAAT 8 T syn10--------
    rs1995106741,2
    F--107207597(+) AGCTGG/ATAAAA 8 /I /V mis11Minor allele frequency- A:0.00EU 1321
    rs2006810461,2
    C--107207639(+) AAGTGC/TTGCAA 6 -- int10--------

    HapMap Linkage Disequilibrium report for DUS4L (107203929 - 107218968 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for DUS4L:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv888940CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    5 diseases for DUS4L:    About MalaCards
    fanconi's anemia    osteoarthritis    anemia    hepatitis b
    hepatitis


    DUS4L for disorders           About GeneDecksing

    Genetic Association Database (GAD): DUS4L
    Human Genome Epidemiology (HuGE) Navigator: DUS4L (2 documents)

    Export disorders for DUS4L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DUS4L gene integrated from 9 sources:
    (articles sorted by number of sources associating them with DUS4L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Meta-analysis of genome-wide association studies conf irms a susceptibility locus for knee osteoarthritis on chromosome 7q22. (PubMed id 21068099)1, 4 Evangelou E....Spector T.D. (2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
    4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    6. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1 Scherer S.W.... Tsui L.-C. (2003)
    7. Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport. (PubMed id 14499622)1 Reuter T.Y....Huber P.A. (2003)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
    10. Generation and analysis of 280,000 human expressed sequence tags. (PubMed id 8889549)1 Hillier L.D....Marra M. (1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11062 HGNC: 21517 AceView: PP35 Ensembl:ENSG00000105865 euGenes: HUgn11062
    ECgene: DUS4L H-InvDB: DUS4L

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DUS4L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DUS4L gene:
    Search GeneIP for patents involving DUS4L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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