DUOX2 Gene
protein-coding GIFtS: 53
GCID: GC15M045384
|
|
dual oxidase 2
| |
Aliases
for DUOX2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Dual Oxidase 21 2 | | P138 Thyroid Oxidase2 3 | | THOX21 2 3 5 | | TDH62 5 | | LNOX21 2 3 | | P138(TOX)1 | | P138-TOX1 2 | | NOXEF22 | | Large NOX 22 3 | | Dual Oxidase-Like Domains 22 | | Long NOX 22 3 | | Flavoprotein NADPH Oxidase2 | | Thyroid Oxidase 22 3 | | Nicotinamide Adenine Dinucleotide Phosphate Oxidase2 | | NADH/NADPH Thyroid Oxidase P138-Tox2 3 | | EC 1.11.1.-3 | | NADPH Oxidase/Peroxidase DUOX22 3 | | EC 1.6.3.13 | | NADPH Thyroid Oxidase 22 3 | | |
Export aliases for DUOX2 gene to outside databasesPrevious GC identifers: GC15M040943 GC15M038431 GC15M042963 GC15M043100 GC15M043172 GC15M022209 |
Summaries
for DUOX2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for DUOX2:
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroidhormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complexcontains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded proteinand DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phoxdomain. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: DUOX2_HUMAN, Q9NRD8Function: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO andlactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense atthe surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain
Gene Wiki entry for DUOX2 (Dual oxidase 2)
|
Genomic Views
for DUOX2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DUOX2 gene promoter:
GR ER-alpha HOXA3 p53 AP-1 GR-beta IRF-1 C/EBPalpha HEN1 GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for DUOX2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DUOX2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q15.3 Ensembl cytogenetic band: 15q21.1 HGNC cytogenetic band: 15q15.3-q21DUOX2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M045384: view genomic region
(about GC identifiers)
Start:
|
45,384,848 bp from pter |
End:
|
45,406,542 bp from pter |
Size:
|
21,695 bases |
Orientation:
|
minus strand |
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Proteins
for DUOX2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DUOX2_HUMAN, Q9NRD8 (See
protein sequence)Recommended Name: Dual oxidase 2 precursor Size: 1548 amino acids; 175364 Da
Subunit: Interacts with TXNDC11, TPO and CYBA
Subcellular location: Apical cell membrane; Multi-pass membrane protein. Note=Localizes to the apical membrane ofepithelial cells
Developmental stage: Widely expressed in fetal tissues
Secondary accessions: A8MQ13 Q9NR02 Q9UHF9Explore the universe of human proteins at neXtProt for DUOX2: NX_Q9NRD8
Post-translational modifications:
N-glycosylated1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NRD8
DUOX2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_054799.4
ENSEMBL proteins: ENSP00000373691
Human Recombinant Protein Products for DUOX2:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- | | GO:0016324 | apical plasma membrane |
IEA | -- |
DUOX2 for ontologies About GeneDecksing
DUOX2 Antibody Products:
Assay Products for DUOX2: |
Protein
Domains /
Families
for DUOX2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DUOX2 for domains About GeneDecksing
5/11 InterPro domains/families (see all 11):Graphical View of Domain Structure for InterPro Entry Q9NRD8ProtoNet protein and cluster: Q9NRD8 1 Blocks protein family: IPB013130 Ferric reductase-like transmembrane component
UniProtKB/Swiss-Prot: DUOX2_HUMAN, Q9NRD8Similarity: In the N-terminal section; belongs to the peroxidase familySimilarity: Contains 3 EF-hand domainsSimilarity: Contains 1 FAD-binding FR-type domainSimilarity: Contains 1 ferric oxidoreductase domain |
Function
for DUOX2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: DUOX2_HUMAN, Q9NRD8Function: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO andlactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense atthe surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domainCatalytic activity: NAD(P)H + O(2) = NAD(P)(+) + H(2)O(2)Enzyme regulation: Peroxidase activity is inhibited by aminobenzohydrazide (By similarity). The NADPH oxidase activityis calcium-dependentInduction: By forskolin, thyrotropin and the Th1-specific cytokine IFNG/IFN-gamma Enzyme Numbers (IUBMB): EC 1.11.1.-1 EC 1.6.3.11
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
DUOX2 for ontologies About GeneDecksing
Phenotypes:
8 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Duox2):
DUOX2 for phenotypes About GeneDecksing
Animal Models:
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DUOX2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: DUOX2 (NM_014080) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DUOX2 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DUOX2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DUOX2 |
|
Pathways & Interactions
for DUOX2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | |
1  BioSystems Pathway for DUOX2
UniProtKB/Swiss-Prot: DUOX2_HUMAN, Q9NRD8Pathway: Hormone biosynthesis; thyroid hormone biosynthesisInteractions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DUOX2
2 Interacting proteins for DUOX2 (Q9NRD83) via UniProtKB, MINT, STRING, and/or I2D About this table
Gene Ontology (GO): 5/16 biological process terms (GO ID links to tree view) (see all 16): About this table
DUOX2 for ontologies About GeneDecksing
|
Drugs & Compounds
for DUOX2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
DUOX2 for compounds About GeneDecksing
 Browse Tocris compounds for DUOX2
5 HMDB Compounds for DUOX2 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Calcium | Ca (see all 2) | 7440-70-2 | -- | | FAD | 1H-Purin-6-amine flavin dinucleotide (see all 21) | 146-14-5 | -- | | Hydrogen peroxide | Hydrogen peroxide (see all 44) | 7722-84-1 | -- | | NAD | 3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28) | 53-84-9 | -- | | NADPH | 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide (see all 23) | 53-57-6 | -- |
9 Novoseek chemical compound relationships for DUOX2 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| iodide |
78.4 |
17 |
16322276 (2), 16987011 (2), 16134168 (1), 17077129 (1) (see all 7) |
| perchlorate |
74.7 |
2 |
16322276 (1) |
| nadph |
73.9 |
11 |
16111680 (2), 17684392 (1), 18281478 (1), 19358684 (1) (see all 8) |
| sodium iodide |
70.8 |
4 |
15863666 (1), 18322142 (1), 17121535 (1) |
| h2o2 |
62 |
16 |
15591162 (2), 17374849 (2), 12824283 (2), 15150274 (2) (see all 9) |
| iodine |
54.3 |
5 |
18426362 (2), 16134168 (1), 18230830 (1) |
| superoxide |
42.4 |
2 |
16987008 (1) |
| oxygen |
32 |
1 |
18281478 (1) |
| sodium |
3.95 |
3 |
16613988 (1), 17077129 (1) |
Search CenterWatch for drugs/clinical trials and news about DUOX2
|
Transcripts
for DUOX2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DUOX2 gene: NM_014080.4 Unigene Cluster for DUOX2: Dual oxidase 2 Hs.71377 [show with all ESTs]Unigene Representative Sequence: AB2090104 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000389039(uc010bea.3 uc001zun.3) ENST00000558383 ENST00000560797
ENST00000558416
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DUOX2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DUOX2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: DUOX2 (NM_014080) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DUOX2 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DUOX2 |
Additional cDNA sequence: AB209010.1 AF181972.1 AF230496.1 AF267981.1 5 DOTS entries: DT.421214 DT.121016786 DT.95228996 DT.91764196 DT.95109547 24/41 AceView cDNA sequences (see all 41): BX282381 AW752673 AA344113 AF181972 AF230496 NM_014080 AA687426 AF267981 AW170493 AW341978 AA687477 BI755312 W60005 AW204802 AL602956 BV197737 AA480160 CD625160 BI059963 BI045475 W52607 AW843489 CD625163 AW855305
GeneLoc Exon Structure
|
Expression
for DUOX2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DUOX2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGTTGTGTG
About this image
See DUOX2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DUOX2
SOURCE GeneReport for Unigene cluster: Hs.71377
UniProtKB/Swiss-Prot: DUOX2_HUMAN, Q9NRD8Tissue specificity: Expressed in colon, small intestine, duodenum and tracheal surface epithelial cells (at proteinlevel). Expressed in thyrocytes. Also detected in kidney, liver, lung, pancreas, prostate, salivary glands, rectum andtestis
SABiosciences Expression via Pathway-Focused PCR Arrays including DUOX2: | Oxidative Stress in human mouse rat | | Nitric Oxide Signaling Pathway in human mouse rat | | Molecular Toxicology PathwayFinder 384HT in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DUOX2
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DUOX2 |
Orthologs
for DUOX2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for DUOX2 gene from 7/21 species (see all 21) About this table
ENSEMBL Gene Tree for DUOX2 (if available)
TreeFam Gene Tree for DUOX2 (if available) |
Paralogs
for DUOX2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DUOX2 gene
- NOX12 CYBB2 NOX32 NOX42 NOX52 DUOX12
2 SIMAP similar genes for DUOX2 using alignment to 2 protein entries: DUOX2_HUMAN (see all proteins):DUOX1 NOX3
DUOX2 for paralogs About GeneDecksing
|
Genomic Variants
for DUOX2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DUOX2 (45384848 - 45406542 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for DUOX2
1 CNV: 3961
1 Indel: 33286
Human Gene Mutation Database (HGMD): DUOX2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DUOX2 |
|
Disorders
/ Diseases
for DUOX2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DUOX2 for disorders About GeneDecksing
OMIM gene information: 606759
OMIM disorders: 607200
UniProtKB/Swiss-Prot: DUOX2_HUMAN, Q9NRD8
Defects in DUOX2 are a cause of thyroid dyshormonogenesis 6 (TDH6) [MIM:607200]. A disorder due to a defectiveconversion of accumulated iodide to organically bound iodine. The iodide organification defect can be partial orcomplete
20/23  diseases for DUOX2 (see all 23): About MalaCardsthyroiditis thryoid dyshormonogenesis 6 pendred syndrome thyroid hormone metabolism
congenital hypothyroidism chronic obstructive pulmonary disease hypothyroidism chronic granulomatous disease
follicular thyroid carcinoma hepatopulmonary syndrome dwarfism pulmonary disease
thyroid carcinoma goiter crohn's disease liver disease
adenoma hepatocellular carcinoma carcinoma pancreatic cancer
3 diseases from the University of Copenhagen DISEASES database for DUOX2:Hypothyroidism Chronic granulomatous disease Vascular disease 6 Novoseek disease relationships for DUOX2 gene About this table
Human Genome Epidemiology (HuGE) Navigator: DUOX2 (10 documents)
Export disorders for DUOX2 gene to outside databases
|
Publications
for DUOX2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DUOX2 gene, integrated from 9 sources (see all 82):
(articles sorted by number of sources associating them with DUOX2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cDNAs. (PubMed id 10601291)1, 2, 3, 9 Dupuy C.... Virion A. (1999)
- Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family. (PubMed id 10806195)1, 2, 3 De Deken X.... Miot F. (2000)
- Dual oxidase2 is expressed all along the digestive tract. (PubMed id 15591162)1, 2, 9 Ameziane-El-Hassani R.... Dupuy C. (2005)
- Persistent mild hypothyroidism associated with novel sequence variants of the DUOX2 gene in two siblings. (PubMed id 16134168)1, 2, 9 Vigone M.C.... Weber G. (2005)
- Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense. (PubMed id 12824283)1, 2, 9 Geiszt M.... Leto T.L. (2003)
- Three mutations (p.Q36H, p.G418fsX482, and g.IVS19-2A-->C) in the dual oxidase 2 gene responsible for congenital goiter and iodide organification defect. (PubMed id 16322276)1, 2, 9 Varela V.... Targovnik H.M. (2006)
- Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system. (PubMed id 11822874)1, 2, 9 De Deken X.... Miot F. (2002)
- Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity. (PubMed id 15972824)1, 2, 9 Ameziane-El-Hassani R.... Dupuy C. (2005)
- Identification of a novel partner of duox: EFP1, a thioredoxin- related protein. (PubMed id 15561711)1, 2 Wang D....Miot F. (2005)
- NADPH oxidase-dependent acid production in airway epithelial cells. (PubMed id 15210697)1, 2 Schwarzer C.... Fischer H. (2004)
|
External Searches for DUOX2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DUOX2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DUOX2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DUOX2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DUOX2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DUOX2 gene:
Search GeneIP for patents involving DUOX2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DUOX2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for DUOX2 | | OriGene shRNA RFP for DUOX2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DUOX2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DUOX2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DUOX2 | | OriGene 3'-UTR Clone for DUOX2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DUOX2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DUOX2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for DUOX2 | | OriGene Custom Protein Services for DUOX2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DUOX2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DUOX2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DUOX2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DUOX2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DUOX2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DUOX2 |
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| | | | Search Tocris compounds for DUOX2 |
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 | | | DUOX2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DUOX2 |
|  |  |  |  | | | | ThermoFisher Antibodies for DUOX2 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DUOX2 |
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