Aliases for DTX4 Gene
External Ids for DTX4 Gene
Previous GeneCards Identifiers for DTX4 Gene
GeneCards Summary for DTX4 Gene
DTX4 (Deltex E3 Ubiquitin Ligase 4) is a Protein Coding gene. Among its related pathways are Cytosolic sensors of pathogen-associated DNA and NOTCH2 Activation and Transmission of Signal to the Nucleus. GO annotations related to this gene include ligase activity. An important paralog of this gene is DTX1.
UniProtKB/Swiss-Prot for DTX4 Gene
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating Lys48-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.