Aliases for DTX4 Gene
External Ids for DTX4 Gene
Previous GeneCards Identifiers for DTX4 Gene
GeneCards Summary for DTX4 Gene
DTX4 (Deltex 4, E3 Ubiquitin Ligase) is a Protein Coding gene. Among its related pathways are Notch signaling pathway (KEGG) and NOTCH2 Activation and Transmission of Signal to the Nucleus. GO annotations related to this gene include ligase activity. An important paralog of this gene is DTX3.
UniProtKB/Swiss-Prot for DTX4 Gene
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating Lys48-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.