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Aliases for DTWD2 Gene

Aliases for DTWD2 Gene

  • DTW Domain Containing 2 2 3

External Ids for DTWD2 Gene

Summaries for DTWD2 Gene

GeneCards Summary for DTWD2 Gene

DTWD2 (DTW Domain Containing 2) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DTWD2 Gene

Genomics for DTWD2 Gene

Genomic Location for DTWD2 Gene

Start:
118,836,874 bp from pter
End:
118,988,545 bp from pter
Size:
151,672 bases
Orientation:
Minus strand

Genomic View for DTWD2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DTWD2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DTWD2 Gene

Proteins for DTWD2 Gene

  • Protein details for DTWD2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NBA8-DTWD2_HUMAN
    Recommended name:
    DTW domain-containing protein 2
    Protein Accession:
    Q8NBA8
    Secondary Accessions:

    Protein attributes for DTWD2 Gene

    Size:
    298 amino acids
    Molecular mass:
    33416 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DTWD2 Gene

Proteomics data for DTWD2 Gene at MOPED

Post-translational modifications for DTWD2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for DTWD2 Gene

No data available for DME Specific Peptides for DTWD2 Gene

Domains for DTWD2 Gene

Protein Domains for DTWD2 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

DTWD2_HUMAN
Domain:
  • Contains 1 DXTW motif:
    • Q8NBA8
Family:
  • Belongs to the DTW family.:
    • Q8NBA8
genes like me logo Genes that share domains with DTWD2: view

No data available for Gene Families for DTWD2 Gene

Function for DTWD2 Gene

miRNA for DTWD2 Gene

miRTarBase miRNAs that target DTWD2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for DTWD2 Gene

Localization for DTWD2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for DTWD2 Gene COMPARTMENTS Subcellular localization image for DTWD2 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Gene Ontology (GO) - Cellular Components for DTWD2 Gene

Pathways for DTWD2 Gene

SuperPathways for DTWD2 Gene

No Data Available

Interacting Proteins for DTWD2 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000425048%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000425048 for DTWD2 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for DTWD2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903955 positive regulation of protein targeting to mitochondrion IMP 24270810
genes like me logo Genes that share ontologies with DTWD2: view

No data available for Pathways by source for DTWD2 Gene

Transcripts for DTWD2 Gene

Unigene Clusters for DTWD2 Gene

DTW domain containing 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DTWD2 Gene

No ASD Table

Relevant External Links for DTWD2 Gene

GeneLoc Exon Structure for
DTWD2
ECgene alternative splicing isoforms for
DTWD2

Expression for DTWD2 Gene

mRNA expression in normal human tissues for DTWD2 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for DTWD2 Gene

SOURCE GeneReport for Unigene cluster for DTWD2 Gene Hs.655891

genes like me logo Genes that share expressions with DTWD2: view

Orthologs for DTWD2 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for DTWD2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia DTWD2 36
  • 99.66 (n)
  • 99.66 (a)
DTWD2 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia DTWD2 36
  • 88.81 (n)
  • 88.59 (a)
DTWD2 37
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 83 (a)
OneToMany
-- 37
  • 81 (a)
OneToMany
DTWD2 36
  • 93.22 (n)
  • 96.02 (a)
mouse
(Mus musculus)
Mammalia Dtwd2 36
  • 85.46 (n)
  • 84.56 (a)
Dtwd2 16
Dtwd2 37
  • 85 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia DTWD2 37
  • 75 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia DTWD2 37
  • 71 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Dtwd2 36
  • 84.45 (n)
  • 84.23 (a)
chicken
(Gallus gallus)
Aves DTWD2 36
  • 76.5 (n)
  • 81.15 (a)
DTWD2 37
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia DTWD2 37
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia dtwd2 36
  • 70.48 (n)
  • 77.55 (a)
Str.17704 36
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.3789 36
zebrafish
(Danio rerio)
Actinopterygii DTWD2 37
  • 57 (a)
OneToOne
si:zfos-1462c8.5 36
  • 59.97 (n)
  • 65.57 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001801 36
  • 45.31 (n)
  • 42.42 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG10050 36
  • 48.28 (n)
  • 43.97 (a)
CG10050 37
  • 41 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G41750 36
  • 44.5 (n)
  • 31.38 (a)
rice
(Oryza sativa)
Liliopsida Os12g0142600 36
  • 47.22 (n)
  • 38.89 (a)
Species with no ortholog for DTWD2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for DTWD2 Gene

ENSEMBL:
Gene Tree for DTWD2 (if available)
TreeFam:
Gene Tree for DTWD2 (if available)

Paralogs for DTWD2 Gene

Pseudogenes.org Pseudogenes for DTWD2 Gene

genes like me logo Genes that share paralogs with DTWD2: view

No data available for Paralogs for DTWD2 Gene

Variants for DTWD2 Gene

Sequence variations from dbSNP and Humsavar for DTWD2 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs10768 -- 118,837,432(+) TTAGA(A/T)CTGAC utr-variant-3-prime
rs169917 -- 118,963,847(+) TAAAG(A/T)TCCTT intron-variant
rs172494 -- 118,986,829(+) ACCTA(A/G)TTAAA intron-variant
rs213434 -- 118,968,695(+) tctca(A/G)cagag intron-variant
rs213435 -- 118,969,107(+) ggggc(C/T)tccct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DTWD2 Gene

Variant ID Type Subtype PubMed ID
nsv882767 CNV Loss 21882294
dgv6305n71 CNV Loss 21882294
esv2557297 CNV Deletion 19546169
nsv526318 CNV Loss 19592680
nsv823191 CNV Loss 20364138
esv2666628 CNV Deletion 23128226

Relevant External Links for DTWD2 Gene

HapMap Linkage Disequilibrium report
DTWD2

Disorders for DTWD2 Gene

Relevant External Links for DTWD2

Genetic Association Database (GAD)
DTWD2
Human Genome Epidemiology (HuGE) Navigator
DTWD2
genes like me logo Genes that share disorders with DTWD2: view

No data available for UniProtKB/Swiss-Prot for DTWD2 Gene

Publications for DTWD2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PMID: 19240061) Trynka G. … Wijmenga C. (Gut 2009) 3 49
  4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  5. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PMID: 22589738) Fox C.S. … Borecki I.B. (PLoS Genet. 2012) 3

Products for DTWD2 Gene

Sources for DTWD2 Gene

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