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Aliases for DTWD1 Gene

Aliases for DTWD1 Gene

  • DTW Domain Containing 1 2 3
  • DTW Domain-Containing Protein 1 3
  • X 009 Protein 3
  • MDS009 3

External Ids for DTWD1 Gene

Summaries for DTWD1 Gene

GeneCards Summary for DTWD1 Gene

DTWD1 (DTW Domain Containing 1) is a Protein Coding gene.

Gene Wiki entry for DTWD1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DTWD1 Gene

Genomics for DTWD1 Gene

Genomic Location for DTWD1 Gene

Start:
49,620,980 bp from pter
End:
49,656,232 bp from pter
Size:
35,253 bases
Orientation:
Plus strand

Genomic View for DTWD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DTWD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DTWD1 Gene

Regulatory Elements for DTWD1 Gene

Proteins for DTWD1 Gene

  • Protein details for DTWD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N5C7-DTWD1_HUMAN
    Recommended name:
    DTW domain-containing protein 1
    Protein Accession:
    Q8N5C7
    Secondary Accessions:
    • Q567Q3
    • Q8WVG9
    • Q9NRU6

    Protein attributes for DTWD1 Gene

    Size:
    304 amino acids
    Molecular mass:
    35248 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF87319.1; Type=Frameshift; Positions=132, 182, 187, 188, 192, 194, 196, 199, 204, 207, 209; Evidence={ECO:0000305};

    Alternative splice isoforms for DTWD1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DTWD1 Gene

Proteomics data for DTWD1 Gene at MOPED

Post-translational modifications for DTWD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for DTWD1 Gene

Domains for DTWD1 Gene

Protein Domains for DTWD1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

DTWD1_HUMAN
Domain:
  • Contains 1 DXTW motif:
    • Q8N5C7
Family:
  • Belongs to the DTW family.:
    • Q8N5C7
genes like me logo Genes that share domains with DTWD1: view

No data available for Gene Families for DTWD1 Gene

Function for DTWD1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for DTWD1 Gene

Localization for DTWD1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for DTWD1 Gene COMPARTMENTS Subcellular localization image for DTWD1 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Gene Ontology (GO) - Cellular Components for DTWD1 Gene

Pathways for DTWD1 Gene

SuperPathways for DTWD1 Gene

No Data Available

Interacting Proteins for DTWD1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000251250%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000251250 for DTWD1 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for DTWD1 Gene

None

No data available for Pathways by source for DTWD1 Gene

Transcripts for DTWD1 Gene

Unigene Clusters for DTWD1 Gene

DTW domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DTWD1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c
SP1: - - - - - - -
SP2: - - -
SP3: - - - - - - - -
SP4: - - - - - -
SP5: - - - - - - - - -
SP6: - - - - -
SP7: -
SP8: - - - - - - -

Relevant External Links for DTWD1 Gene

GeneLoc Exon Structure for
DTWD1
ECgene alternative splicing isoforms for
DTWD1

Expression for DTWD1 Gene

mRNA expression in normal human tissues for DTWD1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for DTWD1 Gene

SOURCE GeneReport for Unigene cluster for DTWD1 Gene Hs.127432

genes like me logo Genes that share expressions with DTWD1: view

Orthologs for DTWD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for DTWD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia DTWD1 36
  • 99.67 (n)
  • 100 (a)
DTWD1 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia DTWD1 37
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia DTWD1 36
  • 93.31 (n)
  • 91.97 (a)
DTWD1 37
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Dtwd1 36
  • 78.84 (n)
  • 73.68 (a)
Dtwd1 16
Dtwd1 37
  • 74 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia DTWD1 37
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia DTWD1 37
  • 61 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Dtwd1 36
  • 79.39 (n)
  • 75.33 (a)
chicken
(Gallus gallus)
Aves DTWD1 37
  • 60 (a)
OneToOne
LOC770318 36
  • 71.28 (n)
  • 69.59 (a)
lizard
(Anolis carolinensis)
Reptilia DTWD1 37
  • 65 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.23765 36
tropical clawed frog
(Silurana tropicalis)
Amphibia dtwd1 36
  • 68.24 (n)
  • 65.75 (a)
Str.17345 36
zebrafish
(Danio rerio)
Actinopterygii dtwd1 36
  • 56.65 (n)
  • 55.97 (a)
dtwd1 37
  • 53 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004295 36
  • 51.7 (n)
  • 47.35 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG2006 36
  • 49.26 (n)
  • 43.37 (a)
CG2006 37
  • 33 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y53C12A.10 36
  • 51.45 (n)
  • 41.54 (a)
Y53C12A.10 37
  • 34 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3444 37
  • 43 (a)
OneToOne
Species with no ortholog for DTWD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for DTWD1 Gene

ENSEMBL:
Gene Tree for DTWD1 (if available)
TreeFam:
Gene Tree for DTWD1 (if available)

Paralogs for DTWD1 Gene

Pseudogenes.org Pseudogenes for DTWD1 Gene

genes like me logo Genes that share paralogs with DTWD1: view

No data available for Paralogs for DTWD1 Gene

Variants for DTWD1 Gene

Sequence variations from dbSNP and Humsavar for DTWD1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs719096 -- 49,637,611(+) CTTGG(C/T)TCCTA intron-variant
rs925103 -- 49,627,643(-) GTACA(A/G)TAACA intron-variant
rs925104 -- 49,624,458(-) TCTTT(A/C)GTACT intron-variant
rs1048348 -- 49,644,041(+) AATTC(C/T)GGTAT utr-variant-3-prime
rs1055135 -- 49,623,978(+) CAAGT(A/G)CCTTT intron-variant

Relevant External Links for DTWD1 Gene

HapMap Linkage Disequilibrium report
DTWD1

No data available for Structural Variations from Database of Genomic Variants (DGV) for DTWD1 Gene

Disorders for DTWD1 Gene

Relevant External Links for DTWD1

Genetic Association Database (GAD)
DTWD1
genes like me logo Genes that share disorders with DTWD1: view

No data available for UniProtKB/Swiss-Prot for DTWD1 Gene

Publications for DTWD1 Gene

  1. Pharmacogenomic study of side-effects for antidepressant treatment options in STAR*D. (PMID: 22041458) Clark S.L. … van den Oord E.J. (Psychol Med 2012) 3 49
  2. A COFRADIC protocol to study protein ubiquitination. (PMID: 24816145) Stes E. … Gevaert K. (J. Proteome Res. 2014) 3
  3. Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study. (PMID: 17903303) O'Donnell C.J. … Demissie S. (BMC Med. Genet. 2007) 49
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 4

Products for DTWD1 Gene

Sources for DTWD1 Gene

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