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Aliases for DTWD1 Gene

Aliases for DTWD1 Gene

  • DTW Domain Containing 1 2 3
  • X 009 Protein 3
  • MDS009 3

External Ids for DTWD1 Gene

Previous GeneCards Identifiers for DTWD1 Gene

  • GC15P047701
  • GC15P049913
  • GC15P026744

Summaries for DTWD1 Gene

GeneCards Summary for DTWD1 Gene

DTWD1 (DTW Domain Containing 1) is a Protein Coding gene.

Gene Wiki entry for DTWD1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DTWD1 Gene

Genomics for DTWD1 Gene

Regulatory Elements for DTWD1 Gene

Genomic Location for DTWD1 Gene

49,620,980 bp from pter
49,656,232 bp from pter
35,253 bases
Plus strand

Genomic View for DTWD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for DTWD1 Gene

Proteins for DTWD1 Gene

  • Protein details for DTWD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    DTW domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • Q567Q3
    • Q8WVG9
    • Q9NRU6

    Protein attributes for DTWD1 Gene

    304 amino acids
    Molecular mass:
    35248 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAF87319.1; Type=Frameshift; Positions=132, 182, 187, 188, 192, 194, 196, 199, 204, 207, 209; Evidence={ECO:0000305};

    Alternative splice isoforms for DTWD1 Gene


neXtProt entry for DTWD1 Gene

Proteomics data for DTWD1 Gene at MOPED

Post-translational modifications for DTWD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for DTWD1 Gene

Domains & Families for DTWD1 Gene

Protein Domains for DTWD1 Gene


Suggested Antigen Peptide Sequences for DTWD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 DXTW motif
  • Belongs to the DTW family.
  • Contains 1 DXTW motif
  • Belongs to the DTW family.
genes like me logo Genes that share domains with DTWD1: view

No data available for Gene Families for DTWD1 Gene

Function for DTWD1 Gene

Phenotypes for DTWD1 Gene

GenomeRNAi human phenotypes for DTWD1:
genes like me logo Genes that share phenotypes with DTWD1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DTWD1 Gene

Localization for DTWD1 Gene

Subcellular locations from

Jensen Localization Image for DTWD1 Gene COMPARTMENTS Subcellular localization image for DTWD1 gene
Compartment Confidence
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for DTWD1 Gene

Pathways & Interactions for DTWD1 Gene

SuperPathways for DTWD1 Gene

No Data Available

Interacting Proteins for DTWD1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000251250 for DTWD1 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for DTWD1 Gene


No data available for Pathways by source and SIGNOR curated interactions for DTWD1 Gene

Drugs & Compounds for DTWD1 Gene

No Compound Related Data Available

Transcripts for DTWD1 Gene

Unigene Clusters for DTWD1 Gene

DTW domain containing 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for DTWD1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for DTWD1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c
SP1: - - - - - - -
SP2: - - -
SP3: - - - - - - - -
SP4: - - - - - -
SP5: - - - - - - - - -
SP6: - - - - -
SP7: -
SP8: - - - - - - -

Relevant External Links for DTWD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DTWD1 Gene

mRNA expression in normal human tissues for DTWD1 Gene

Protein differential expression in normal tissues from HIPED for DTWD1 Gene

This gene is overexpressed in Ovary (54.1) and Adrenal (12.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for DTWD1 Gene

SOURCE GeneReport for Unigene cluster for DTWD1 Gene Hs.127432

genes like me logo Genes that share expression patterns with DTWD1: view

Protein tissue co-expression partners for DTWD1 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for DTWD1 Gene

Orthologs for DTWD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for DTWD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia DTWD1 35
  • 93.31 (n)
  • 91.97 (a)
DTWD1 36
  • 92 (a)
(Mus musculus)
Mammalia Dtwd1 35
  • 78.84 (n)
  • 73.68 (a)
Dtwd1 16
Dtwd1 36
  • 74 (a)
(Pan troglodytes)
Mammalia DTWD1 35
  • 99.67 (n)
  • 100 (a)
DTWD1 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Dtwd1 35
  • 79.39 (n)
  • 75.33 (a)
(Bos Taurus)
Mammalia DTWD1 36
  • 86 (a)
(Monodelphis domestica)
Mammalia DTWD1 36
  • 74 (a)
(Ornithorhynchus anatinus)
Mammalia DTWD1 36
  • 61 (a)
(Gallus gallus)
Aves LOC770318 35
  • 71.28 (n)
  • 69.59 (a)
DTWD1 36
  • 60 (a)
(Anolis carolinensis)
Reptilia DTWD1 36
  • 65 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia dtwd1 35
  • 68.24 (n)
  • 65.75 (a)
Str.17345 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.23765 35
(Danio rerio)
Actinopterygii dtwd1 35
  • 56.65 (n)
  • 55.97 (a)
dtwd1 36
  • 53 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004295 35
  • 51.7 (n)
  • 47.35 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG2006 35
  • 49.26 (n)
  • 43.37 (a)
CG2006 36
  • 33 (a)
(Caenorhabditis elegans)
Secernentea Y53C12A.10 35
  • 51.45 (n)
  • 41.54 (a)
Y53C12A.10 36
  • 34 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3444 36
  • 43 (a)
Species with no ortholog for DTWD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for DTWD1 Gene

Gene Tree for DTWD1 (if available)
Gene Tree for DTWD1 (if available)

Paralogs for DTWD1 Gene Pseudogenes for DTWD1 Gene

genes like me logo Genes that share paralogs with DTWD1: view

No data available for Paralogs for DTWD1 Gene

Variants for DTWD1 Gene

Sequence variations from dbSNP and Humsavar for DTWD1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs719096 -- 49,637,611(+) CTTGG(C/T)TCCTA intron-variant
rs925103 -- 49,627,643(-) GTACA(A/G)TAACA intron-variant
rs925104 -- 49,624,458(-) TCTTT(A/C)GTACT intron-variant
rs1048348 -- 49,644,041(+) AATTC(C/T)GGTAT utr-variant-3-prime, intron-variant
rs1055135 -- 49,623,978(+) CAAGT(A/G)CCTTT intron-variant

Variation tolerance for DTWD1 Gene

Residual Variation Intolerance Score: 40.95% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.26; 40.59% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for DTWD1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for DTWD1 Gene

Disorders for DTWD1 Gene

Relevant External Links for DTWD1

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with DTWD1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DTWD1 Gene

Publications for DTWD1 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. Pharmacogenomic study of side-effects for antidepressant treatment options in STAR*D. (PMID: 22041458) Clark S.L. … van den Oord E.J. (Psychol Med 2012) 67
  3. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P. … Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012) 67
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 67
  5. Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study. (PMID: 17903303) O'Donnell C.J. … Demissie S. (BMC Med. Genet. 2007) 67

Products for DTWD1 Gene

Sources for DTWD1 Gene

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