Set Analyses:
GeneALaCart
GeneAnalytics
VarElect
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 


DTHD1 Gene

protein-coding   GIFtS: 43
GCID: GC04P036283

Death Domain Containing 1

  Try our
MalaCards

disease database 

Aliases
for DTHD1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus
Aliases
Death Domain Containing 11 2
Death Domain-Containing Protein 12

External Ids:    HGNC: 372611   Entrez Gene: 4011242   Ensembl: ENSG000001970577   UniProtKB: Q6ZMT93   

Export aliases for DTHD1 gene to outside databases

Previous GC identifers: GC04P035961 GC04P035609


Summaries
for DTHD1 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus
Entrez Gene summary for DTHD1 Gene:
This gene encodes a protein which contains a death domain. Death domain-containing proteins function in signaling
pathways and formation of signaling complexes, as well as the apoptosis pathway. Alternative splicing results in
multiple transcript variants. (provided by RefSeq, Oct 2012)

GeneCards Summary for DTHD1 Gene:
DTHD1 (death domain containing 1) is a protein-coding gene.




Genomic Views
for DTHD1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NT_006238.12  NC_018915.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for DTHD1
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for DTHD1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DTHD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p14   Ensembl cytogenetic band:  4p14   HGNC cytogenetic band: 4p14

DTHD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DTHD1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P036283:  view genomic region     (about GC identifiers)

Start:
 36,283,244 bp from pter      End:
 36,347,378 bp from pter
Size:
 64,135 bases      Orientation:
 plus strand

Proteins
for DTHD1 gene

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus
UniProtKB/Swiss-Prot: DTHD1_HUMAN, Q6ZMT9 (See protein sequence)
Recommended Name: Death domain-containing protein 1  
Size: 781 amino acids; 88329 Da
Secondary accessions: B2RXK4 B4E2N7
Alternative splicing: 2 isoforms:  Q6ZMT9-1   Q6ZMT9-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DTHD1: NX_Q6ZMT9

Explore proteomics data for DTHD1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

    • See DTHD1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001130008.2  NP_001164171.1  

    ENSEMBL proteins: 
     ENSP00000350103   ENSP00000424426   ENSP00000401597  

    DTHD1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for DTHD1
    GenScript Custom Purified and Recombinant Proteins Services for DTHD1
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DTHD1

         		 Search eBioscience for Proteins for DTHD1 

         		antibodies-online proteins for DTHD1 

         		 Search antibodies-online for peptides for DTHD1

    DTHD1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for DTHD1
    Novus Biologicals DTHD1 Antibody
    Abcam antibodies for DTHD1
    Cloud-Clone Corp. Antibodies for DTHD1
    Search ThermoFisher Antibodies for DTHD1
    Search antibodies-online for antibodies for DTHD1 

    DTHD1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for DTHD1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for DTHD1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for DTHD1
    Cloud-Clone Corp. CLIAs for DTHD1
    Search eBioscience for ELISAs for DTHD1 
    antibodies-online kits for DTHD1 

    Domains /
    Families
    for DTHD1 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus    		 2 InterPro protein domains:
     IPR011029 DEATH-like_dom
     IPR000488 Death_domain

    Graphical View of Domain Structure for InterPro Entry Q6ZMT9

    ProtoNet protein and cluster: Q6ZMT9

    1 Blocks protein domain: IPB000488 Death domain

    UniProtKB/Swiss-Prot: DTHD1_HUMAN, Q6ZMT9
    Similarity: Contains 1 death domain


    Find genes that share domains with DTHD1           About GenesLikeMe


    Function
    for DTHD1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with DTHD1           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for DTHD1

    miRNA
    Products:            		Block miRNA regulation of human, mouse, rat DTHD1 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate DTHD1:
    hsa-miR-3616-5p hsa-miR-3647-5p hsa-miR-3935 hsa-miR-105 hsa-miR-573 hsa-miR-3662 hsa-miR-3674 hsa-miR-3668
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		OriGene RNAi products in human, mouse, rat for DTHD1
    Predesigned siRNA for gene silencing in human, mouse, rat DTHD1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for DTHD1

    Clone
    Products:             		 OriGene clones in human, mouse for DTHD1 (see all 10)
    OriGene ORF clones in mouse, rat for DTHD1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): DTHD1 (NM_001136536)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DTHD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DTHD1

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for DTHD1
    Browse ESI BIO Cell Lines and PureStem Progenitors for DTHD1 
    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DTHD1


    Localization
    for DTHD1 gene

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2

    Pathways & Interactions
    for DTHD1 gene

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus





        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DTHD1
    Interactions:

        Search GeneGlobe Interaction Network for DTHD1

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction IEA--

    Find genes that share ontologies with DTHD1           About GenesLikeMe



    Drugs & Compounds
    for DTHD1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DTHD1



    Transcripts
    for DTHD1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus
    REFSEQ mRNAs for DTHD1 gene (2 alternative transcripts): 
    NM_001136536.4  NM_001170700.2  

    Unigene Cluster for DTHD1:

    Death domain containing 1
    Hs.363407  [show with all ESTs]
    Unigene Representative Sequence: NM_001170700
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000357504 ENST00000507598 ENST00000506008 ENST00000503528(uc003gsv.3)
    ENST00000456874(uc011bxy.2 uc021xne.1)
    miRNA
    Products:             		 Block miRNA regulation of human, mouse, rat DTHD1 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate DTHD1:
    hsa-miR-3616-5p hsa-miR-3647-5p hsa-miR-3935 hsa-miR-105 hsa-miR-573 hsa-miR-3662 hsa-miR-3674 hsa-miR-3668
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		OriGene RNAi products in human, mouse, rat for DTHD1
    Predesigned siRNA for gene silencing in human, mouse, rat DTHD1
    Clone
    Products:             		 OriGene clones in human, mouse for DTHD1 (see all 10)
    OriGene ORF clones in mouse, rat for DTHD1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): DTHD1 (NM_001136536)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DTHD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DTHD1
    Primer
    Products:            		OriGene qSTAR qPCR primer pairs in human, mouse for DTHD1
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat DTHD1
      QuantiTect SYBR Green Assays in human, mouse, rat DTHD1
      QuantiFast Probe-based Assays in human, mouse, rat DTHD1

    Additional mRNA sequence: 

    AK094684.1 AK131492.1 AK304357.1 AK316523.1 BC157885.1 NR_073198.1 

    2 DOTS entries:

    DT.102821129  DT.99933060 

    8 AceView cDNA sequences:

    AK131492 BM978838 AI125835 AA954477 AK094684 BU607760 BX102378 CD694599 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for DTHD1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b
    SP1:        -                                         -     -                     
    SP2:                                                              -               
    SP3:                                                                              


    ECgene alternative splicing isoforms for DTHD1

    Expression
    for DTHD1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    DTHD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTCAGCACCA
    DTHD1 Expression
    About this image

    DTHD1 Protein expression data from MOPED1, PaxDb2 and MaxQB3:     About this image

    DTHD1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.363407
        Custom PCR Arrays for DTHD1
    Primer
    Products:    		OriGene qSTAR qPCR primer pairs in human, mouse for DTHD1
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat DTHD1
    QuantiTect SYBR Green Assays in human, mouse, rat DTHD1
    QuantiFast Probe-based Assays in human, mouse, rat DTHD1
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DTHD1

    Orthologs
    for DTHD1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus
    This gene was present in the common ancestor of chordates.

    Orthologs for DTHD1 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Gm173841 , 5 predicted gene, 173841, 5 81.12(n)1
    74.77(a)1    		   5 (32.04 cM)5
    1003228961  NM_001170705.11  NP_001164176.11 
     628138235 
    chicken
    (Gallus gallus)    		 Aves DTHD11 death domain containing 1 63.78(n)
    53.51(a)    		   100858463  XM_003641216.2  XP_003641264.1 
    lizard
    (Anolis carolinensis)    		 Reptilia DTHD16
    		 death domain containing 1
    		 52(a)
    		 1 ↔ 1
    		 GL343598.1(129711-156475)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia LOC1017346891 death domain-containing protein 1-like 61.11(n)
    51.41(a)    		   101734689  XM_004919452.1  XP_004919509.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii LOC1005367691 death domain-containing protein 1-like 49.38(n)
    41.65(a)    		   100536769  XM_003198997.2  XP_003199045.2 


    ENSEMBL Gene Tree for DTHD1 (if available)
    TreeFam Gene Tree for DTHD1 (if available)

    Paralogs
    for DTHD1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus    		  --

    Genomic Variants
    for DTHD1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus
    Selected SNPs for DTHD1 (see all 1218)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 4 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs107181421,2
    		C--35629723(+) CTCCCT/-TTTTT 2 -- int1 trp32Minor allele frequency- -:0.25NA CSA 4
    rs2003515501,2
    		C--35629723(+) CTCCCC/TTTTTT 2 -- int10--------
    rs725960741,2
    		C--35631523(+) AGTTC-/ACGTAG 2 -- int10--------
    rs1452847231,2
    		--36172423(+) TCTTAC/TATCTC 1 -- us2k10--------
    rs1384695611,2
    		--36172445(+) ACATCC/TGCATC 1 -- us2k10--------
    rs1890399401,2
    		--36172456(+) TCTACA/GGCACA 1 -- us2k10--------
    rs1814325321,2
    		--36172478(+) ATTGCA/CGTCTG 1 -- us2k10--------
    rs169920231,2
    		C,F,H--36172583(+) TCTGAC/TTCGTT 1 -- us2k19Minor allele frequency- T:0.09NA NS EA CSA WA 682
    rs1855236821,2
    		--36172666(+) TGATCA/GTATTA 1 -- us2k10--------
    rs1420232601,2
    		--36172680(+) CCTATA/GCTGGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DTHD1 (36283244 - 36347378 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for DTHD1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv4301CNV Insertion18451855
    esv1393189CNV Insertion17803354
    esv268366CNV Insertion20981092
    nsv829907CNV Gain17160897

    Human Gene Mutation Database (HGMD): DTHD1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DTHD1
    DNA2.0 Custom Variant and Variant Library Synthesis for DTHD1

    Disorders / Diseases
    for DTHD1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus    		 1 inferred disease relationship from the University of Copenhagen DISEASES database for DTHD1:
    Fundus dystrophy

    Find genes that share disorders with DTHD1           About GenesLikeMe

    Genetic Association Database (GAD): DTHD1

    Export disorders for DTHD1 gene to outside databases

    Publications
    for DTHD1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus
    PubMed articles for DTHD1 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with DTHD1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Autozygome-guided exome sequencing in retinal dystrophy patients reveals pathogenetic mutations and novel candidate disease genes. (PubMed id 23105016)1 Abu-Safieh L....Alkuraya F.S. (Genome Res. 2013)
    3. Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis. (PubMed id 20802204)4 Baranzini S.E....Pelletier D. (Brain 2010)
    4. The death domain superfamily in intracellular signaling of apoptosis and inflammation. (PubMed id 17201679)1 Park H.H....Wu H. (Annu. Rev. Immunol. 2007)
    5. Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study. (PubMed id 17903297)4 Seshadri S....Wolf P.A. (BMC Med. Genet. 2007)
    6. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    7. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PubMed id 17903300)4 Fox C.S....Atwood L.D. (BMC Med. Genet. 2007)
    8. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PubMed id 17903294)4 Yang Q....O'Donnell C.J. (BMC Med. Genet. 2007)
    9. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    External Searches for DTHD1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing DTHD1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 401124 HGNC: 37261 AceView: FLJ16686 Ensembl:ENSG00000197057 euGenes: HUgn401124
    ECgene: DTHD1 H-InvDB: DTHD1

    Other Databases showing DTHD1 gene

    (According to HUGE)
    About This Section

    TryGeneCards Plus    		   --

    Specialized Databases showing DTHD1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for DTHD1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for DTHD1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus    		Patent Information for DTHD1 gene:
    Search GeneIP for patents involving DTHD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for DTHD1 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus
     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for DTHD1  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for DTHD1  
     OriGene qSTAR qPCR primer pairs in human, mouse for DTHD1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for DTHD1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for DTHD1   OriGene Custom Protein Services for DTHD1  

         		 
     Block miRNA regulation of human, mouse, rat DTHD1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing DTHD1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DTHD1 Predesigned siRNA for gene silencing in human, mouse, rat DTHD1
     QuantiFast Probe-based Assays in human, mouse, rat DTHD1 QuantiTect SYBR Green Assays in human, mouse, rat DTHD1
     Custom PCR Arrays for DTHD1 Search Chromatin IP Primers for DTHD1
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat DTHD1  Search GeneGlobe Interaction Network for DTHD1
     Search Regulatory tfbs for DTHD1
     GenScript Custom Purified and Recombinant Proteins Services for DTHD1 GenScript cDNA clones with any tag delivered in your preferred vector for DTHD1
     GenScript Custom Assay Services for DTHD1 GenScript Custom overexpressing Cell Line Services for DTHD1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for DTHD1
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     DTHD1 antibodies
     Antibodies for DTHD1
     See all of Abcam's Antibodies, Kits and Proteins for DTHD1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for DTHD1
     Antibodies for DTHD1
     ELISAs for DTHD1
     CLIAs for DTHD1



     Browse ESI BIO Cell Lines and PureStem Progenitors for DTHD1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DTHD1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for DTHD1
     Browse SwitchGear Promoter luciferase reporter plasmids for DTHD1
     Search ThermoFisher Antibodies for DTHD1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DTHD1
     Browse compounds at ApexBio
     Search Addgene for plasmids for DTHD1
      Search eBioscience for proteins for DTHD1
      Search eBioscience for elisas for DTHD1
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for DTHD1
      Search antibodies-online for antibodies for DTHD1
     antibodies-online kits for DTHD1
      Search antibodies-online for peptides for DTHD1
     antibodies-online proteins for DTHD1
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 2 Nov 2014 , 8 Jan 2015

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2015 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      DTHD1 gene at Home site.
    Version: 3.12.304 29 Jan 2015
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4