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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DSTYK Gene

protein-coding GIFtS: 58
GCID: GC01M205111

Dual Serine/Threonine And Tyrosine Protein Kinase

(Previous name: receptor interacting protein kinase 5)
(Previous symbol: RIPK5)

Microbiology & Infectious Diseases Congress

See related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Dual Serine/Threonine And Tyrosine Protein Kinase¹ ²		EC 2.7.12.1³ ⁸
RIPK5¹ ² ³		KIAA0472³ ⁵
RIP5² ³ ⁵		CAKUT1²
Receptor Interacting Protein Kinase 5¹ ²		DustyPK²
Dusty PK² ³		Receptor Interacting Protein 5²
Dusty Protein Kinase² ³		sgK496²
Receptor-Interacting Serine/Threonine-Protein Kinase 5² ³		SGK496³
Sugen Kinase 496² ³		SgK496³
RIP-Homologous Kinase² ³		DUSTYPK⁵

External Ids:	HGNC: 29043¹	Entrez Gene: 25778²	Ensembl: ENSG00000133059⁷	OMIM: 612666⁵	UniProtKB: Q6XUX3³

Export aliases for DSTYK gene to outside databases

Previous GC identifers: GC01M203379 GC01M176276

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DSTYK Gene:

This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It

is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoforms

have been found for this gene. (provided by RefSeq, Dec 2008)

GeneCards Summary for DSTYK Gene:

DSTYK (dual serine/threonine and tyrosine protein kinase) is a protein-coding gene. Diseases associated with DSTYK include sarcoma, and prostatitis. GO annotations related to this gene include protein serine/threonine/tyrosine kinase activity and protein serine/threonine kinase activity. An important paralog of this gene is MATK.

UniProtKB/Swiss-Prot: DUSTY_HUMAN, Q6XUX3

Function: May induce both caspase-dependent apoptosis and caspase-independent cell death

Gene Wiki entry for DSTYK (RIPK5) Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.2 NT_004487.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DSTYK gene promoter:
POU2F2 (Oct-2.1) Oct-B1 oct-B3 p53 oct-B2 POU2F2 POU2F2C POU2F1 POU2F1a POU2F2B
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DSTYK promoter sequence

Search SABiosciences Chromatin IP Primers for DSTYK

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DSTYK

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.1 Ensembl cytogenetic band: 1q32.1 HGNC cytogenetic band: 1q32

DSTYK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DSTYK gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M205111: view genomic region (about GC identifiers)

Start:	205,111,631 bp from pter	End:	205,180,727 bp from pter
Size:	69,097 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DUSTY_HUMAN, Q6XUX3 (See protein sequence)

Recommended Name: Dual serine/threonine and tyrosine protein kinase

Size: 929 amino acids; 105206 Da

Subcellular location: Cytoplasm

Secondary accessions: B7ZL64 O75060 Q17R94 Q5RKT0 Q6IN87 Q6P997 Q86Y03 Q9P1S5

Alternative splicing: 4 isoforms: Q6XUX3-1 Q6XUX3-2 Q6XUX3-3 Q6XUX3-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DSTYK: NX_Q6XUX3

Explore proteomics data for DSTYK at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q6XUX3

4/33 DME Specific Peptides for DSTYK (Q6XUX3) (see all 33)

YELVHTL

WKRKVAQ

AFDMQRD

ETLNTMK

DSTYK Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins (2 alternative transcripts):

NP_056190.1 NP_955749.1

ENSEMBL proteins:

ENSP00000356129 ENSP00000356130 ENSP00000356128

Human Recombinant Protein Products for DSTYK:

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	Cloud-Clone Corp. Proteins for DSTYK

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005730	NOT nucleolus	IDA	--
GO:0005737	cytoplasm	IEA	--
GO:0045111	intermediate filament cytoskeleton	IDA	--

DSTYK for ontologies About GeneDecksing

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

IUPHAR Guide to PHARMACOLOGY protein family classification: dual serine/threonine and tyrosine protein kinase

Other-unique family

4 InterPro protein domains:

IPR017441 Protein_kinase_ATP_BS

IPR011009 Kinase-like_dom

IPR008271 Ser/Thr_kinase_AS

IPR000719 Prot_kinase_cat_dom

Graphical View of Domain Structure for InterPro Entry Q6XUX3

ProtoNet protein and cluster: Q6XUX3

UniProtKB/Swiss-Prot: DUSTY_HUMAN, Q6XUX3

Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family

Similarity: Contains 1 protein kinase domain

DSTYK for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: DUSTY_HUMAN, Q6XUX3

Function: May induce both caspase-dependent apoptosis and caspase-independent cell death

Catalytic activity: ATP + a protein = ADP + a phosphoprotein

Enzyme Number (IUBMB): EC 2.7.12.1¹ ²

Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004672	protein kinase activity	--	--
GO:0004674	protein serine/threonine kinase activity	IEA	--
GO:0004712	protein serine/threonine/tyrosine kinase activity	IEA	--
GO:0004713	protein tyrosine kinase activity	IEA	--
GO:0005524	ATP binding	IEA	--

DSTYK for ontologies About GeneDecksing

Phenotypes:
5 GenomeRNAi human phenotypes for DSTYK:

Decreased cell number, increas	Decreased cilium length after	Decreased substrate adherent c	Increased colony dispersion (i
Synthetic lethal with Ras

Animal Models:

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		8/78 QIAGEN miScript miRNA Assays for microRNAs that regulate DSTYK (see all 78):
		hsa-miR-323-3p hsa-miR-520f hsa-miR-640 hsa-miR-3152-3p hsa-miR-199a-3p hsa-miR-106a hsa-miR-200a hsa-miR-485-3p

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DSTYK

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DSTYK

STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

5/16 Interacting proteins for DSTYK (Q6XUX3³ ENSP00000356130⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 16)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
DDT	P30046³, ENSP00000215773⁴	I2D: score=2 STRING: ENSP00000215773
HSPE1	P61604³, ENSP00000233893⁴	I2D: score=2 STRING: ENSP00000233893
PSMB1	P20618³, ENSP00000262193⁴	I2D: score=2 STRING: ENSP00000262193
RAB14	P61106³, ENSP00000362946⁴	I2D: score=2 STRING: ENSP00000362946
RAB5C	P51148³, ENSP00000345689⁴	I2D: score=2 STRING: ENSP00000345689

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006468	protein phosphorylation	--	--

DSTYK for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DSTYK (DUSTY)

2 HMDB Compounds for DSTYK About this table

Compound	Synonyms	CAS #	PubMed Ids
ADP	adenosindiphosphorsaeure (see all 8)	58-64-0	--
Adenosine triphosphate	5'-(tetrahydrogen triphosphate) Adenosine (see all 24)	56-65-5	--

Search CenterWatch for drugs/clinical trials and news about DSTYK / DUSTY

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DSTYK gene (2 alternative transcripts):

NM_015375.2 NM_199462.2

Unigene Cluster for DSTYK:

Dual serine/threonine and tyrosine protein kinase

Hs.6874 [show with all ESTs]

Unigene Representative Sequence: NM_015375

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000367161(uc001hby.1 uc001hbx.3) ENST00000367162(uc001hbw.3)

ENST00000367160

Congresses - knowledge worth sharing:
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DSTYK
		8/78 QIAGEN miScript miRNA Assays for microRNAs that regulate DSTYK (see all 78):
		hsa-miR-323-3p hsa-miR-520f hsa-miR-640 hsa-miR-3152-3p hsa-miR-199a-3p hsa-miR-106a hsa-miR-200a hsa-miR-485-3p

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Additional mRNA sequence:

AB007941.1 AF068286.1 AJ420466.1 AK298011.1 AY208850.1 AY429674.1 BC018303.1 BC048204.1

BC053627.1 BC060870.1 BC072406.1 BC117411.1 BC143603.1

8 DOTS entries:

DT.101980615 DT.411427 DT.91746948 DT.95272142 DT.95201181 DT.411428 DT.111320 DT.75152585

24/192 AceView cDNA sequences (see all 192):

BM694016 AY208850 F04547 NM_015375 BE252310 BC053627 AI094827 AI093230

BF025947 AI948556 F02725 AI689310 AA635138 CA943816 BC072406 AI784481

BQ271688 N42371 BC018303 BU168830 BX281845 BM684173 BU170290 AA975916

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for DSTYK About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	^	5	^	6a	·	6b	^	7	^	8a	·	8b	^	9	^	10	^	11a	·	11b	^	12	^	13a	·	13b
SP1:																							-
SP2:																							-										-
SP3:
SP4:																	-		-		-		-		-		-		-				-

ECgene alternative splicing isoforms for DSTYK

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DSTYK expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GTGAGCCGAG

About this image

See DSTYK Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DSTYK

SOURCE GeneReport for Unigene cluster: Hs.6874

UniProtKB/Swiss-Prot: DUSTY_HUMAN, Q6XUX3

Tissue specificity: Predominantly expressed in skeletal muscle and testis. Weakly expressed in heart, brain,

placenta, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine, white blood cells, stomach, spinal

cord and adrenal gland. Is widely distributed in the CNS. Also detected in several tumor cell lines

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for DSTYK gene from 6/11 species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Dstyk^{1 , 5}	dual serine/threonine and tyrosine protein kinase^{1, 5}	88.53(n)¹ 91.48(a)¹		1 (57.24 cM)⁵ 213452¹ NM_172516.4¹ NP_766104.2¹ 132417453⁵
chicken (Gallus gallus)	Aves	DSTYK¹	dual serine/threonine and tyrosine protein kinase	74.68(n) 79.45(a)		395171 NM_204506.2 NP_989837.1
lizard (Anolis carolinensis)	Reptilia	DSTYK⁶	dual serine/threonine and tyrosine protein kinase	78(a)	1 ↔ 1	4(116222328-116276851)
African clawed frog (Xenopus laevis)	Amphibia	Xl.5447²	Xenopus laevis transcribed sequence with weak similarity more	77.37(n)		48043888
zebrafish (Danio rerio)	Actinopterygii	Dr.13169²	Danio rerio dusty protein kinase mRNA, complete cds	74.33(n)		AY208855.1
worm (Caenorhabditis elegans)	Secernentea	C34F11.5⁶ F23C8.7⁶ (see all 36)	Protein F23C8.7 (see all 36)	6(a) 16(a) (see all 36)	1 ↔ many 1 ↔ many (see all 36)	II(5195895-5199259) I(2422334-2425073)

ENSEMBL Gene Tree for DSTYK (if available)
TreeFam Gene Tree for DSTYK (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for DSTYK gene

MATK² FER² CSK² FES²

1 SIMAP similar gene for DSTYK using alignment to 2 protein entries: DUSTY_HUMAN (see all proteins):

CDK4

DSTYK for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs117884285^1,2	C,F	untested¹	205160532(+)	`AGCACA/G/TAGAAT`	2	--	int¹		1		EA	120
rs3862947^1,2	C	--	176310919(-)	`TTTTT-/TTTT /TTTTTAAGAG`	2	--	int¹		1		NA	2
rs116294703^1,2		--	205111218(+)	`GCCAGC/TGTAAG`	2	--	ds500¹		0	--	--	--	--
rs141667755^1,2	C	--	205111246(+)	`CTCACA/CATGTA`	2	--	ds500¹		0	--	--	--	--
rs16855154^1,2	C,F	--	205111275(+)	`GCTCAT/CATATG`	2	--	ds500¹		12		NA WA CSA EA	512
rs191493139^1,2		--	205111313(+)	`AAAAGA/CAGCTG`	2	--	ds500¹		0	--	--	--	--
rs117727576^1,2	F	--	205111317(+)	`GAAGCT/AGGAAA`	2	--	ds500¹		1		EA	120
rs146212115^1,2		--	205111454(+)	`CAAGAA/GCCATG`	2	--	ds500¹		0	--	--	--	--
rs12749303^1,2	C,F,H	--	205111493(+)	`GGAACA/GTGTTC`	2	--	ds500¹		8		NS EA NA	544
rs7554368^1,2	C,F,H	--	205111643(-)	`GATCAC/TATTAA`	2	--	ut3¹		7		NS EA CSA WA	538

HapMap Linkage Disequilibrium report for DSTYK (205111631 - 205180727 bp)

Structural Variations
Database of Genomic Variants (DGV) 4 variations for DSTYK: About this table

Variant ID	Type	Subtype	PubMed ID
esv2721918	CNV	Deletion	23290073
esv2721906	CNV	Deletion	23290073
nsv468016	CNV	Loss	19166990
esv1503810	OTHER	Inversion	17803354

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 612666 OMIM disorders: --

2 diseases for DSTYK: About MalaCards

sarcoma prostatitis

DSTYK for disorders About GeneDecksing

Genetic Association Database (GAD): DSTYK
Human Genome Epidemiology (HuGE) Navigator: DSTYK (1 document)

Export disorders for DSTYK gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for DSTYK gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with DSTYK)

Utopia: connect your pdf to the dynamic
world of online information

RIP5 is a RIP-homologous inducer of cell death. (PubMed id 15178406)^{1, 2, 3} Zha J.... Shu H.B. (2004)
Dusty protein kinases: primary structure, gene evolution, tissue specific expression and unique features of the catalytic domain. (PubMed id 17123648)^{1, 2} Peng J....Huang C.-H. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. (PubMed id 9455484)^{1, 2} Seki N.... Ohara O. (1997)
Mutations in DSTYK and dominant urinary tract malforma tions. (PubMed id 23862974)¹ Sanna-Cherchi S....Gharavi A.G. (2013)
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)¹ Comuzzie A.G....Butte N.F. (2012)
Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)⁴ Israni A....Oetting W.S. (2010)
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)² Gauci S....Mohammed S. (2009)
Large-scale proteomics analysis of the human kinome. (PubMed id 19369195)² Oppermann F.S.... Daub H. (2009)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 25778	HGNC: 29043	AceView: RIPK5	Ensembl:ENSG00000133059	euGenes: HUgn25778
ECgene: DSTYK	H-InvDB: DSTYK

(According to HUGE)
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HUGE: KIAA0472

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for DSTYK	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DSTYK gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for DSTYK gene:
Search GeneIP for patents involving DSTYK

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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Dual Serine/Threonine And Tyrosine Protein Kinase

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Dual Serine/Threonine And Tyrosine Protein Kinase

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