Aliases for DSTYK Gene
External Ids for DSTYK Gene
Previous HGNC Symbols for DSTYK Gene
Previous GeneCards Identifiers for DSTYK Gene
This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
GeneCards Summary for DSTYK Gene
DSTYK (Dual Serine/Threonine And Tyrosine Protein Kinase) is a Protein Coding gene. Diseases associated with DSTYK include congenital anomalies of kidney and urinary tract and unilateral renal agenesis. GO annotations related to this gene include protein serine/threonine kinase activity and protein serine/threonine/tyrosine kinase activity. An important paralog of this gene is FER.
UniProtKB/Swiss-Prot for DSTYK Gene
Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death.