Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



DSEL Gene

protein-coding   GIFtS: 50
GCID: GC18M065173

Dermatan Sulfate Epimerase-Like

(Previous name: chromosome 18 open reading frame 4)
(Previous symbol: C18orf4)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Dermatan Sulfate Epimerase-Like1 2
C18orf41 2 3 5
NCAG12 3 5
Chromosome 18 Open Reading Frame 41
Dermatan-Sulfate Epimerase-Like Protein2
EC 5.1.-.-3

External Ids:    HGNC: 181441   Entrez Gene: 921262   Ensembl: ENSG000001714517   OMIM: 6111255   UniProtKB: Q8IZU83   

Export aliases for DSEL gene to outside databases

Previous GC identifers: GC18M063325 GC18M061894


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for DSEL Gene:
DSEL (dermatan sulfate epimerase-like) is a protein-coding gene. Diseases associated with DSEL include congenital diaphragmatic hernia, and major depressive disorder. GO annotations related to this gene include isomerase activity and sulfotransferase activity. An important paralog of this gene is DSE.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000018.10  NC_018929.2  NT_010966.15  
Regulatory elements:
   Regulatory transcription factor binding sites in the DSEL gene promoter:
         Sox5   LHX3b/Lhx3b   CUTL1   HNF-1A   HNF-1   LHX3a/Lhx3a   Chx10   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDSEL promoter sequence
   Search Chromatin IP Primers for DSEL

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DSEL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q22.1   Ensembl cytogenetic band:  18q22.1   HGNC cytogenetic band: 18q22.1

DSEL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DSEL gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18M065173:  view genomic region     (about GC identifiers)

Start:
65,173,819 bp from pter      End:
65,184,217 bp from pter
Size:
10,399 bases      Orientation:
minus strand

1 alternative location:
Chr18-,NW_003315960 152,309-162,457     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: DSEL_HUMAN, Q8IZU8 (See protein sequence)
Recommended Name: Dermatan-sulfate epimerase-like protein precursor  
Size: 1212 amino acids; 139238 Da
Sequence caution: Sequence=AAI17326.1; Type=Erroneous initiation; Sequence=AAN32895.1; Type=Erroneous initiation;
Secondary accessions: Q17RH1 Q6P5Z3

Explore the universe of human proteins at neXtProt for DSEL: NX_Q8IZU8

Explore proteomics data for DSEL at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn28, Asn666, Asn688, Asn709, Asn874
  • Modification sites at PhosphoSitePlus

  • See DSEL Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_115536.1  
    ENSEMBL proteins: 
     ENSP00000310565  
    Reactome Protein details: Q8IZU8

    DSEL Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for DSEL
    GenScript Custom Purified and Recombinant Proteins Services for DSEL
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DSEL

    DSEL Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for DSEL
    Search for Antibodies for DSEL at Abcam
    Cloud-Clone Corp. Antibodies for DSEL
    Search ThermoFisher Antibodies for DSEL
    Search LSBio for Antibodies for DSEL

    DSEL Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for DSEL
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for DSEL
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for DSEL
    Cloud-Clone Corp. CLIAs for DSEL


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    2 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR000863 Sulfotransferase_dom

    Graphical View of Domain Structure for InterPro Entry Q8IZU8

    ProtoNet protein and cluster: Q8IZU8

    UniProtKB/Swiss-Prot: DSEL_HUMAN, Q8IZU8
    Similarity: Belongs to the dermatan-sulfate isomerase family


    DSEL for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Enzyme Number (IUBMB): EC 5.1.-.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008146sulfotransferase activity IEA--
    GO:0016853isomerase activity IEA--
         
    DSEL for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for DSEL:
     Decreased Wnt reporter activit 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DSEL
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DSEL

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DSEL
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DSEL

    miRNA
    Products:
        
    miRTarBase miRNAs that target DSEL:
    hsa-mir-124-3p (MIRT022150)

    Block miRNA regulation of human, mouse, rat DSEL using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DSEL (see all 106):
    hsa-miR-579 hsa-miR-3678-3p hsa-miR-3152-3p hsa-miR-3607-3p hsa-miR-631 hsa-miR-15a hsa-miR-605 hsa-miR-374a
    SwitchGear 3'UTR luciferase reporter plasmidDSEL 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for DSEL
    Predesigned siRNA for gene silencing in human, mouse, rat DSEL

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for DSEL

    Clone
    Products:
         
    OriGene clones in human, mouse for DSEL (see all 7)
    OriGene ORF clones in mouse, rat for DSEL
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DSEL (NM_032160)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DSEL
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DSEL

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for DSEL
    Browse ESI BIO Cell Lines and PureStem Progenitors for DSEL 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DSEL


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    DSEL_HUMAN, Q8IZU8: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0016021integral component of membrane IEA--

    DSEL for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for DSEL About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1MPS VI - Maroteaux-Lamy syndrome
    MPS VI - Maroteaux-Lamy syndrome0.45
    MPS IIIB - Sanfilippo syndrome B0.45
    MPS IIIC - Sanfilippo syndrome C0.45
    MPS II - Hunter syndrome0.45
    MPS IV - Morquio syndrome A0.45
    Glycosaminoglycan metabolism0.45
    Mucopolysaccharidoses0.45
    MPS IV - Morquio syndrome B0.45
    2Chondroitin sulfate/dermatan sulfate metabolism
    Chondroitin sulfate/dermatan sulfate metabolism0.51
    Dermatan sulfate biosynthesis0.00
    3Metabolism
    Metabolism0.38
    4Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for DSEL
        Dermatan sulfate biosynthesis



    DSEL for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DSEL
    Interactions:

        Search GeneGlobe Interaction Network for DSEL

    1 Interacting protein for DSEL (Q8IZU83) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRKAG2Q9UGJ03I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0030203glycosaminoglycan metabolic process TAS--
    GO:0030204chondroitin sulfate metabolic process TAS--
    GO:0030208dermatan sulfate biosynthetic process TAS--
    GO:0044281small molecule metabolic process TAS--

    DSEL for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DSEL



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for DSEL gene: 
    NM_032160.2  

    Unigene Cluster for DSEL:

    Dermatan sulfate epimerase-like
    Hs.124673  [show with all ESTs]
    Unigene Representative Sequence: AF480435
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000310045(uc002lke.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat DSEL using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DSEL (see all 106):
    hsa-miR-579 hsa-miR-3678-3p hsa-miR-3152-3p hsa-miR-3607-3p hsa-miR-631 hsa-miR-15a hsa-miR-605 hsa-miR-374a
    SwitchGear 3'UTR luciferase reporter plasmidDSEL 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for DSEL
    Predesigned siRNA for gene silencing in human, mouse, rat DSEL
    Clone
    Products:
         
    OriGene clones in human, mouse for DSEL (see all 7)
    OriGene ORF clones in mouse, rat for DSEL
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DSEL (NM_032160)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DSEL
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DSEL
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for DSEL
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DSEL
      QuantiTect SYBR Green Assays in human, mouse, rat DSEL
      QuantiFast Probe-based Assays in human, mouse, rat DSEL

    Additional mRNA sequence: 

    AF480435.1 AK021539.1 AK021849.1 AK023067.1 BC062557.1 BC117325.1 

    2 DOTS entries:

    DT.40211427  DT.121097854 

    Selected AceView cDNA sequences (see all 44):

    AA374532 AI088531 BC062557 AW015616 CF140658 CD723635 C01922 AW450489 
    BU956522 AW139834 AI139422 AI791264 BP372824 BM546309 BU619658 AK023067 
    BX114873 NM_032160 CB154870 BP348589 AU130218 AA858162 AF480435 BE139460 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    DSEL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATAGATTCA
    DSEL Expression
    About this image

    DSEL Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DSEL Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.124673

    UniProtKB/Swiss-Prot: DSEL_HUMAN, Q8IZU8
    Tissue specificity: Expressed in different brain areas as well as in multiple other peripheral tissues

        Custom PCR Arrays for DSEL
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for DSEL
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DSEL
    QuantiTect SYBR Green Assays in human, mouse, rat DSEL
    QuantiFast Probe-based Assays in human, mouse, rat DSEL
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DSEL

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for DSEL gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dsel1 , 5 dermatan sulfate epimerase-like1, 5 88.73(n)1
    89.73(a)1
      1 (50.84 cM)5
    3199011  NM_001081316.11  NP_001074785.11 
     1118587025 
    chicken
    (Gallus gallus)
    Aves DSEL1 dermatan sulfate epimerase-like 76.49(n)
    78.05(a)
      421028  XM_004935223.1  XP_004935280.1 
    lizard
    (Anolis carolinensis)
    Reptilia DSEL6
    dermatan sulfate epimerase-like
    77(a)
    1 ↔ 1
    4(45808436-45812098)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia dsel1 dermatan sulfate epimerase-like 70.65(n)
    70.87(a)
      100493402  XM_002939614.2  XP_002939660.1 
    zebrafish
    (Danio rerio)
    Actinopterygii dsela1 dermatan sulfate epimerase-like a 62.78(n)
    61.32(a)
      568099  XM_691410.3  XP_696502.2 


    ENSEMBL Gene Tree for DSEL (if available)
    TreeFam Gene Tree for DSEL (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for DSEL gene
    DSE2  
    1 SIMAP similar gene for DSEL using alignment to 1 protein entry:     DSEL_HUMAN:
    DSE

    DSEL for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for DSEL (see all 269)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0365284
    A colorectal cancer sample4--see VAR_0365282 K E mis40--------
    rs1874773771,2
    --65173375(+) AGCGAA/GACTCC 1 -- ds50010--------
    rs589281841,2
    C--65173415(+) AAAAA-/AAA/AA
    AAAAAAAAA
    GCATC
    1 -- ds50011NA 2
    rs1496624591,2
    C--65173496(+) TTTTAC/GTGATA 1 -- ds50010--------
    rs749862611,2
    F--65173666(+) AAGGAC/ACAAGT 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs1920335661,2
    --65173874(+) CATAGC/GTCTGA 1 -- ut310--------
    rs115527101,2
    C,F,H--65173941(-) TTTTTC/TCTTCA 1 -- ut314Minor allele frequency- T:0.01NS NA 450
    rs1851526631,2
    --65173951(+) ACGACA/GACGAA 1 -- ut310--------
    rs1458861981,2
    --65173954(+) ACGACA/GAACAA 1 -- ut310--------
    rs1896790991,2
    --65174111(+) TTGTTG/TGAAGT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DSEL (65173819 - 65184217 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DSEL:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv458102CNV Loss19166990
    nsv909748CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DSEL
    DNA2.0 Custom Variant and Variant Library Synthesis for DSEL

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 611125    OMIM disorders: --

    7 diseases for DSEL:    
    About MalaCards
    congenital diaphragmatic hernia    major depressive disorder    microphthalmia    breast and colorectal cancer
    bipolar disorder    hepatocellular carcinoma    colorectal cancer


    DSEL for disorders           About GeneDecksing

    Genetic Association Database (GAD): DSEL
    Human Genome Epidemiology (HuGE) Navigator: DSEL (2 documents)

    Export disorders for DSEL gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for DSEL gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with DSEL)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome-wide association study of recurrent early-onset major depressive disorder. (PubMed id 20125088)1, 4 Shi J....Levinson D.F. (Mol. Psychiatry 2011)
    2. A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. (PubMed id 19734545)1, 4 Need A.C....Goldstein D.B. (Hum. Mol. Genet. 2009)
    3. Biosynthesis of dermatan sulfate: chondroitin-glucuronate C5- epimerase is identical to SART2. (PubMed id 16505484)1, 3 Maccarana M.... Malmstroem A. (J. Biol. Chem. 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. A novel CpG-associated brain-expressed candidate gene for chromosome 18q-linked bipolar disorder. (PubMed id 12556911)1, 2 Goossens D.... Del-Favero J. (Mol. Psychiatry 2003)
    6. A yeast two-hybrid screen reveals that osteopontin associates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain. (PubMed id 22779921)1 Long P....Rose S. (Eur. J. Neurosci. 2012)
    7. A maternally inherited chromosome 18q22.1 deletion in a male with late-presenting diaphragmatic hernia and microphthalmia-evaluation of DSEL as a candidate gene for the diaphragmatic defect. (PubMed id 20358601)1 Zayed H....Slavotinek A.M. (Am. J. Med. Genet. A 2010)
    8. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    9. DNA sequence and analysis of human chromosome 18. (PubMed id 16177791)2 Nusbaum C.... Lander E.S. (Nature 2005)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 92126 HGNC: 18144 AceView: C18orf4 Ensembl:ENSG00000171451 euGenes: HUgn92126
    ECgene: DSEL H-InvDB: DSEL

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for DSEL Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for DSEL gene:
    Search GeneIP for patents involving DSEL

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for DSEL  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for DSEL  
     OriGene qSTAR qPCR primer pairs in human, mouse for DSEL   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for DSEL   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for DSEL   OriGene Custom Protein Services for DSEL  

     
     
     Block miRNA regulation of human, mouse, rat DSEL using miScript Target Protectors SeqTarget long-range PCR primers for resequencing DSEL
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DSEL Predesigned siRNA for gene silencing in human, mouse, rat DSEL
     QuantiFast Probe-based Assays in human, mouse, rat DSEL QuantiTect SYBR Green Assays in human, mouse, rat DSEL
     Custom PCR Arrays for DSEL Search Chromatin IP Primers for DSEL
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DSEL  Search GeneGlobe Interaction Network for DSEL
     Regulatory tfbs in DSEL promoter
     GenScript Custom Purified and Recombinant Proteins Services for DSEL GenScript cDNA clones with any tag delivered in your preferred vector for DSEL
     GenScript Custom Assay Services for DSEL GenScript Custom overexpressing Cell Line Services for DSEL
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for DSEL
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Biologicals
     Novus Tissue Slides
     Search for Antibodies for DSEL at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for DSEL
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for DSEL
     Antibodies for DSEL
     ELISAs for DSEL
     CLIAs for DSEL



     Browse ESI BIO Cell Lines and PureStem Progenitors for DSEL
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DSEL
     SwitchGear 3'UTR luciferase reporter plasmids for DSEL
     SwitchGear Promoter luciferase reporter plasmids for DSEL
     Search ThermoFisher Antibodies for DSEL
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DSEL
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DSEL
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DSEL
     Search LSBio for Antibodies for DSEL
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      DSEL gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4