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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DSEL Gene

protein-coding   GIFtS: 44
GCID: GC18M065173

Dermatan Sulfate Epimerase-Like

(Previous name: chromosome 18 open reading frame 4)
(Previous symbol: C18orf4)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Dermatan Sulfate Epimerase-Like1 2
C18orf41 2 3 5
NCAG12 3 5
Chromosome 18 Open Reading Frame 41
Dermatan-Sulfate Epimerase-Like Protein2
EC 5.1.-.-3

External Ids:    HGNC: 181441   Entrez Gene: 921262   Ensembl: ENSG000001714517   OMIM: 6111255   UniProtKB: Q8IZU83   

Export aliases for DSEL gene to outside databases

Previous GC identifers: GC18M063325 GC18M061894


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for DSEL Gene: 
DSEL (dermatan sulfate epimerase-like) is a protein-coding gene. Diseases associated with DSEL include congenital diaphragmatic hernia, and hernia. GO annotations related to this gene include isomerase activity and sulfotransferase activity. An important paralog of this gene is DSE.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NC_018929.2  NT_025028.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DSEL gene promoter:
         Sox5   LHX3b/Lhx3b   CUTL1   HNF-1A   HNF-1   LHX3a/Lhx3a   Chx10   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDSEL promoter sequence
   Search SABiosciences Chromatin IP Primers for DSEL

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DSEL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q22.1   Ensembl cytogenetic band:  18q22.1   HGNC cytogenetic band: 18q22.1

DSEL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DSEL gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18M065173:  view genomic region     (about GC identifiers)

Start:
65,173,819 bp from pter      End:
65,184,217 bp from pter
Size:
10,399 bases      Orientation:
minus strand

1 alternative location:
Chr18-,NW_003315960 152,309-162,457     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DSEL_HUMAN, Q8IZU8 (See protein sequence)
Recommended Name: Dermatan-sulfate epimerase-like protein precursor  
Size: 1212 amino acids; 139238 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=AAI17326.1; Type=Erroneous initiation; Sequence=AAN32895.1; Type=Erroneous initiation;
Secondary accessions: Q17RH1 Q6P5Z3

Explore the universe of human proteins at neXtProt for DSEL: NX_Q8IZU8

Explore proteomics data for DSEL at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8IZU8

  • DSEL Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DSEL Protein Expression
    REFSEQ proteins: NP_115536.1  
    ENSEMBL proteins: 
     ENSP00000310565  

    Human Recombinant Protein Products for DSEL: 
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    Cloud-Clone Corp. Proteins for DSEL 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--

    DSEL for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for DSEL


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR000863 Sulfotransferase_dom

    Graphical View of Domain Structure for InterPro Entry Q8IZU8

    ProtoNet protein and cluster: Q8IZU8

    UniProtKB/Swiss-Prot: DSEL_HUMAN, Q8IZU8
    Similarity: Belongs to the dermatan-sulfate isomerase family


    DSEL for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Enzyme Number (IUBMB): EC 5.1.-.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008146sulfotransferase activity IEA--
    GO:0016853isomerase activity IEA--
         
    DSEL for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for DSEL:
     Decreased Wnt reporter activit 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for DSEL 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DSEL

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DSEL 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DSEL 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DSEL
    8/106 QIAGEN miScript miRNA Assays for microRNAs that regulate DSEL (see all 106):
    hsa-miR-579 hsa-miR-3678-3p hsa-miR-3152-3p hsa-miR-3607-3p hsa-miR-631 hsa-miR-15a hsa-miR-605 hsa-miR-374a
    SwitchGear 3'UTR luciferase reporter plasmidDSEL 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for DSEL
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    Gene Editing
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    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for DSEL (see all 7)
    OriGene ORF clones in mouse, rat for DSEL
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DSEL (NM_032160)
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                         Customized lentivirus expression plasmids for stable overexpression of DSEL 

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    Search LifeMap BioReagents cell lines for DSEL
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DSEL


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DSEL

    1 Interacting protein for DSEL (Q8IZU83) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRKAG2Q9UGJ03I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DSEL

    Search CenterWatch for drugs/clinical trials and news about DSEL

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DSEL gene: 
    NM_032160.2  

    Unigene Cluster for DSEL:

    Dermatan sulfate epimerase-like
    Hs.124673  [show with all ESTs]
    Unigene Representative Sequence: AF480435
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000310045(uc002lke.1)
    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DSEL
    8/106 QIAGEN miScript miRNA Assays for microRNAs that regulate DSEL (see all 106):
    hsa-miR-579 hsa-miR-3678-3p hsa-miR-3152-3p hsa-miR-3607-3p hsa-miR-631 hsa-miR-15a hsa-miR-605 hsa-miR-374a
    SwitchGear 3'UTR luciferase reporter plasmidDSEL 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for DSEL
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DSEL
    Clone
    Products:
         
    OriGene clones in human, mouse for DSEL (see all 7)
    OriGene ORF clones in mouse, rat for DSEL
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DSEL (NM_032160)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DSEL
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DSEL
    Sirion Biotech Customized lentivirus for stable overexpression of DSEL 
                         Customized lentivirus expression plasmids for stable overexpression of DSEL 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for DSEL
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DSEL
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DSEL
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DSEL

    Additional mRNA sequence: 

    AF480435.1 AK021539.1 AK021849.1 AK023067.1 BC062557.1 BC117325.1 

    2 DOTS entries:

    DT.40211427  DT.121097854 

    24/44 AceView cDNA sequences (see all 44):

    AI088531 AW139834 C01922 AI791264 CF140658 AA374532 AW450489 BC062557 
    BU956522 AI139422 CD723635 AW015616 CB154870 NM_032160 AU130218 AF480435 
    BU619658 BE139460 BP348589 C03813 CD519984 BX114873 AI401481 CK724875 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DSEL expression in normal human tissues (normalized intensities)      DSEL embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATAGATTCA
    DSEL Expression
    About this image


    DSEL expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Smooth Muscle (Muscoskeletal System)
             Human Pulmonary Artery Smooth Muscle Cells (HPASMC)   
     
     Lung (Muscoskeletal System)
             Human Pulmonary Artery Smooth Muscle Cells (HPASMC)   
     
     Breast (Uncategorized)
             Human Mammary Fibroblasts (HMF)   
     
     Pancreas (Endocrine System)
             Pancreatic endoderm/endocrine precursor-like cells ( A scalable, suspension protocol...
     
     Eye (Sensory Organs)
             Human Keratocyte (HK)   

    See DSEL Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DSEL

    SOURCE GeneReport for Unigene cluster: Hs.124673

    UniProtKB/Swiss-Prot: DSEL_HUMAN, Q8IZU8
    Tissue specificity: Expressed in different brain areas as well as in multiple other peripheral tissues

        SABiosciences Custom PCR Arrays for DSEL
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DSEL
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DSEL

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for DSEL gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dsel1 , 5 dermatan sulfate epimerase-like1, 5 88.73(n)1
    89.73(a)1
      1 (50.84 cM)5
    3199011  NM_001081316.11  NP_001074785.11 
     1118587025 
    chicken
    (Gallus gallus)
    Aves DSEL1 dermatan sulfate epimerase-like 76.49(n)
    78.05(a)
      421028  XM_419114.2  XP_419114.2 
    lizard
    (Anolis carolinensis)
    Reptilia DSEL6
    Uncharacterized protein
    77(a)
    1 ↔ 1
    4(45808436-45812098)
    zebrafish
    (Danio rerio)
    Actinopterygii dsel1 dermatan sulfate epimerase-like 62.98(n)
    61.54(a)
      568099  XM_691410.2  XP_696502.2 


    ENSEMBL Gene Tree for DSEL (if available)
    TreeFam Gene Tree for DSEL (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DSEL gene
    DSE2  
    1 SIMAP similar gene for DSEL using alignment to 1 protein entry:     DSEL_HUMAN:
    DSE

    DSEL for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/269 SNPs in DSEL are shown (see all 269)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0365284
    A colorectal cancer sample4--see VAR_0365282 K E mis40--------
    rs1874773771,2
    --65173375(+) AGCGAA/GACTCC 1 -- ds50010--------
    rs589281841,2
    C--65173415(+) AAAAA-/AAA/AA
    AAAAAAAAA
    GCATC
    1 -- ds50011NA 2
    rs1496624591,2
    C--65173496(+) TTTTAC/GTGATA 1 -- ds50010--------
    rs749862611,2
    F--65173666(+) AAGGAC/ACAAGT 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs1920335661,2
    --65173874(+) CATAGC/GTCTGA 1 -- ut310--------
    rs115527101,2
    C,F,H--65173941(-) TTTTTC/TCTTCA 1 -- ut314Minor allele frequency- T:0.01NS NA 450
    rs1851526631,2
    --65173951(+) ACGACA/GACGAA 1 -- ut310--------
    rs1458861981,2
    --65173954(+) ACGACA/GAACAA 1 -- ut310--------
    rs1896790991,2
    --65174111(+) TTGTTG/TGAAGT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DSEL (65173819 - 65184217 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DSEL:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv458102CNV Loss19166990
    nsv909748CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing DSEL
    DNA2.0 Custom Variant and Variant Library Synthesis for DSEL

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611125    OMIM disorders: --

    6 diseases for DSEL:    About MalaCards
    congenital diaphragmatic hernia    hernia    major depressive disorder    microphthalmia
    bipolar disorder    hepatocellular carcinoma


    DSEL for disorders           About GeneDecksing

    Genetic Association Database (GAD): DSEL
    Human Genome Epidemiology (HuGE) Navigator: DSEL (2 documents)

    Export disorders for DSEL gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DSEL gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with DSEL)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome-wide association study of recurrent early-onse t major depressive disorder. (PubMed id 20125088)1, 4 Shi J....Levinson D.F. (2010)
    2. A genome-wide study of common SNPs and CNVs in cognit ive performance in the CANTAB. (PubMed id 19734545)1, 4 Need A.C....Goldstein D.B. (2009)
    3. Biosynthesis of dermatan sulfate: chondroitin-glucuronate C5- epimerase is identical to SART2. (PubMed id 16505484)1, 3 Maccarana M.... Malmstroem A. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. A novel CpG-associated brain-expressed candidate gene for chromosome 18q-linked bipolar disorder. (PubMed id 12556911)1, 2 Goossens D.... Del-Favero J. (2003)
    6. A yeast two-hybrid screen reveals that osteopontin ass ociates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain. (PubMed id 22779921)1 Long P....Rose S. (2012)
    7. A maternally inherited chromosome 18q22.1 deletion in a male with late-presenting diaphragmatic hernia and microphthalmia-evaluation of DSEL as a candidate gene for the diaphragmatic defect. (PubMed id 20358601)1 Zayed H....Slavotinek A.M. (2010)
    8. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    9. DNA sequence and analysis of human chromosome 18. (PubMed id 16177791)2 Nusbaum C.... Lander E.S. (2005)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 92126 HGNC: 18144 AceView: C18orf4 Ensembl:ENSG00000171451 euGenes: HUgn92126
    ECgene: DSEL H-InvDB: DSEL

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DSEL Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DSEL gene:
    Search GeneIP for patents involving DSEL

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
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     Browse Antibodies   Browse Cell Culture Products  
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     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for DSEL  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
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     OriGene Custom Antibody Services for DSEL   OriGene Custom Protein Services for DSEL  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DSEL
     QIAGEN SeqTarget long-range PCR primers for resequencing DSEL
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DSEL
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DSEL
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     Search for Antibodies & Assays

     Regulatory tfbs in DSEL promoter
     Search Chromatin IP Primers for DSEL
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     Browse Sino Biological Proteins and Antibodies
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
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     Search for Antibodies for DSEL at Abcam
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     Proteins for DSEL
     Antibodies for DSEL
     ELISAs for DSEL
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     Search LifeMap BioReagents cell lines for DSEL
     Gene Synthesis
     Protein Engineering
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     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DSEL
     SwitchGear 3'UTR luciferase reporter plasmids for DSEL
     SwitchGear Promoter luciferase reporter plasmids for DSEL
     Search ThermoFisher Antibodies for DSEL
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DSEL
     inGenious Targeting Laboratory - Custom generated mouse model solutions for DSEL
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DSEL
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     Search LSBio for Antibodies for DSEL
    Customized transgenic rodents for:
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     Tissue-specific gene expresssion
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
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