Aliases for DSE Gene
External Ids for DSE Gene
Previous HGNC Symbols for DSE Gene
Previous GeneCards Identifiers for DSE Gene
The protein encoded by this gene is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is localized to the endoplasmic reticulum. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for DSE Gene
DSE (Dermatan Sulfate Epimerase) is a Protein Coding gene. Diseases associated with DSE include ehlers-danlos syndrome, musculocontractural type 2 and ehlers-danlos syndrome, musculocontractural type. Among its related pathways are Metabolism and Glycosaminoglycan metabolism. GO annotations related to this gene include chondroitin-glucuronate 5-epimerase activity. An important paralog of this gene is DSEL.
UniProtKB/Swiss-Prot for DSE Gene
Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues.