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Aliases for DSCR10 Gene

Subcategory (RNA class) for DSCR10 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for DSCR10 Gene

  • Down Syndrome Critical Region 10 (Non-Protein Coding) 2 3 5
  • Down Syndrome Critical Region Gene 10 2

External Ids for DSCR10 Gene

Previous GeneCards Identifiers for DSCR10 Gene

  • GC21U990114
  • GC21P036238
  • GC21P038498
  • GC21P038500
  • GC21P039578
  • GC21P025047

Summaries for DSCR10 Gene

GeneCards Summary for DSCR10 Gene

DSCR10 (Down Syndrome Critical Region 10 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with DSCR10 include Down Syndrome.

Additional gene information for DSCR10 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DSCR10 Gene

Genomics for DSCR10 Gene

Regulatory Elements for DSCR10 Gene

Enhancers for DSCR10 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH21H038983 2.5 VISTA FANTOM5 Ensembl ENCODE dbSUPER 14.6 +783.3 783269 11.3 PKNOX1 FOXA2 MLX ARNT ARID4B YBX1 FEZF1 ZNF2 ZNF766 CBX5 HMGN1 RNF6P1 MYL6P2 DSCR10 LOC100288590 DSCR4 DSCR4-IT1 DSCR8 ETS2 ENSG00000235888
GH21H038906 2 FANTOM5 Ensembl ENCODE dbSUPER 14.6 +705.3 705274 9.7 HDGF PKNOX1 FOXA2 MLX SIN3A YBX1 ZBTB7B YY1 ZNF302 ZNF207 HMGN1 LCA5L RNF6P1 DSCR4 MYL6P2 DSCR10 LOC100288590 DSCR4-IT1 PSMG1 DSCR8
GH21H038733 1.4 Ensembl ENCODE dbSUPER 14.6 +529.1 529116 3.5 RB1 TBL1XR1 ZSCAN4 ARID4B ZNF2 RAD21 RARA RFX5 ZNF143 RCOR1 RNF6P1 DSCR4 DSCR10 LOC100288590 MYL6P2 DSCR4-IT1 ERG RPSAP64 DSCR8 KCNJ6
GH21H038219 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +14.0 14030 2.4 TBP TBL1XR1 ARNT RAD21 CHAMP1 TCF12 CBX5 ZNF350 ZNF143 ATF7 ENSG00000242553 KCNJ15 DSCR10 GC21M038236
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around DSCR10 on UCSC Golden Path with GeneCards custom track

Genomic Locations for DSCR10 Gene

Genomic Locations for DSCR10 Gene
2,489 bases
Plus strand

Genomic View for DSCR10 Gene

Genes around DSCR10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DSCR10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DSCR10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DSCR10 Gene

Proteins for DSCR10 Gene

  • Protein details for DSCR10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Down syndrome critical region protein 10
    Protein Accession:
    Secondary Accessions:
    • Q52LN2

    Protein attributes for DSCR10 Gene

    87 amino acids
    Molecular mass:
    9286 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DSCR10 Gene

Post-translational modifications for DSCR10 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DSCR10 Gene

Domains & Families for DSCR10 Gene

Protein Domains for DSCR10 Gene


Suggested Antigen Peptide Sequences for DSCR10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DSCR10: view

No data available for Gene Families and UniProtKB/Swiss-Prot for DSCR10 Gene

Function for DSCR10 Gene

Phenotypes From GWAS Catalog for DSCR10 Gene

Gene Ontology (GO) - Molecular Function for DSCR10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with DSCR10: view

Phenotypes for DSCR10 Gene

GenomeRNAi human phenotypes for DSCR10:
genes like me logo Genes that share phenotypes with DSCR10: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DSCR10 Gene

Localization for DSCR10 Gene

Gene Ontology (GO) - Cellular Components for DSCR10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with DSCR10: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for DSCR10 Gene

Pathways & Interactions for DSCR10 Gene

SuperPathways for DSCR10 Gene

No Data Available

Interacting Proteins for DSCR10 Gene

Selected Interacting proteins: P59022-DSC10_HUMAN for DSCR10 Gene via UniProtKB

Gene Ontology (GO) - Biological Process for DSCR10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with DSCR10: view

No data available for Pathways by source and SIGNOR curated interactions for DSCR10 Gene

Drugs & Compounds for DSCR10 Gene

No Compound Related Data Available

Transcripts for DSCR10 Gene

mRNA/cDNA for DSCR10 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DSCR10 Gene

Down syndrome critical region gene 10 (non-protein coding):
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for DSCR10 Gene

No ASD Table

Relevant External Links for DSCR10 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DSCR10 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DSCR10 Gene

mRNA differential expression in normal tissues according to GTEx for DSCR10 Gene

This gene is overexpressed in Testis (x51.6).

NURSA nuclear receptor signaling pathways regulating expression of DSCR10 Gene:


SOURCE GeneReport for Unigene cluster for DSCR10 Gene:


mRNA Expression by UniProt/SwissProt for DSCR10 Gene:

Tissue specificity: Expressed in placenta and testis.
genes like me logo Genes that share expression patterns with DSCR10: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DSCR10 Gene

Orthologs for DSCR10 Gene

Evolution for DSCR10 Gene

Gene Tree for DSCR10 (if available)
Gene Tree for DSCR10 (if available)

No data available for Orthologs for DSCR10 Gene

Paralogs for DSCR10 Gene

No data available for Paralogs for DSCR10 Gene

Variants for DSCR10 Gene

Sequence variations from dbSNP and Humsavar for DSCR10 Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type
rs1000436063 -- 38,205,762(+) GATTG(A/G)CAAGC upstream-variant-2KB
rs1000891752 -- 38,205,432(+) CCATA(G/T)ATTTT upstream-variant-2KB
rs1001280491 -- 38,205,689(+) ACTCA(C/T)TTTTC upstream-variant-2KB
rs1001513706 -- 38,204,845(+) CTGAG(C/T)TCTTT upstream-variant-2KB
rs1001948560 -- 38,205,874(+) AGAAC(A/C)CCTTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for DSCR10 Gene

Variant ID Type Subtype PubMed ID
nsv1122042 CNV deletion 24896259
nsv1072602 CNV deletion 25765185
nsv1058886 CNV gain 25217958

Relevant External Links for DSCR10 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for DSCR10 Gene

Disorders for DSCR10 Gene

MalaCards: The human disease database

(1) MalaCards diseases for DSCR10 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
down syndrome
  • leukemia, megakaryoblastic, with or without down syndrome, somatic
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for DSCR10

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with DSCR10: view

No data available for UniProtKB/Swiss-Prot and Genatlas for DSCR10 Gene

Publications for DSCR10 Gene

  1. Identification of two novel primate-specific genes in DSCR. (PMID: 12168953) Takamatsu K … Takeda T (DNA research : an international journal for rapid publication of reports on genes and genomes 2002) 2 3 4 60
  2. Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. (PMID: 20485444) Wang Y … Huang W (Journal of human genetics 2010) 3 45 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for DSCR10 Gene

Sources for DSCR10 Gene

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