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Aliases for DSCR10 Gene

Subcategory (RNA class) for DSCR10 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for DSCR10 Gene

  • Down Syndrome Critical Region 10 (Non-Protein Coding) 2 3 5
  • Down Syndrome Critical Region Gene 10 2

External Ids for DSCR10 Gene

Previous GeneCards Identifiers for DSCR10 Gene

  • GC21U990114
  • GC21P036238
  • GC21P038498
  • GC21P038500
  • GC21P039578
  • GC21P025047

Summaries for DSCR10 Gene

GeneCards Summary for DSCR10 Gene

DSCR10 (Down Syndrome Critical Region 10 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with DSCR10 include Down Syndrome.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DSCR10 Gene

Genomics for DSCR10 Gene

Regulatory Elements for DSCR10 Gene

Enhancers for DSCR10 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH21G038219 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +14.0 14030 2.4 ARNT RAD21 CHAMP1 TCF12 CBX5 ZNF350 ZNF143 IKZF2 ZNF654 MIER1 ENSG00000242553 KCNJ15 DSCR10 GC21M038236
GH21G038227 1.2 FANTOM5 ENCODE dbSUPER 0.3 +22.2 22245 1.5 RBBP5 DPF2 E2F1 GATA3 CTBP1 HDAC2 BCL11A NBN TRIM28 KCNJ15 GC21M038236 DSCR10
GH21G038229 1.1 ENCODE dbSUPER 0.3 +23.2 23243 0.1 CBX3 KLF17 ZNF155 ZNF23 ZNF302 CBX5 ZNF416 ZNF350 ZNF143 ZNF548 GC21M038236 DSCR10
GH21G038233 1 ENCODE dbSUPER 0.3 +28.8 28763 2.0 PKNOX1 NFIB JUN BMI1 RAD21 CTBP1 GATA3 FOSL2 FOS RCOR1 KCNJ15 GC21M038236 DSCR10
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around DSCR10 on UCSC Golden Path with GeneCards custom track

Genomic Location for DSCR10 Gene

38,206,156 bp from pter
38,208,644 bp from pter
2,489 bases
Plus strand

Genomic View for DSCR10 Gene

Genes around DSCR10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DSCR10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DSCR10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DSCR10 Gene

Proteins for DSCR10 Gene

  • Protein details for DSCR10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Down syndrome critical region protein 10
    Protein Accession:
    Secondary Accessions:
    • Q52LN2

    Protein attributes for DSCR10 Gene

    87 amino acids
    Molecular mass:
    9286 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DSCR10 Gene

Post-translational modifications for DSCR10 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DSCR10 Gene

Domains & Families for DSCR10 Gene

Protein Domains for DSCR10 Gene


Suggested Antigen Peptide Sequences for DSCR10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DSCR10: view

No data available for Gene Families and UniProtKB/Swiss-Prot for DSCR10 Gene

Function for DSCR10 Gene

Gene Ontology (GO) - Molecular Function for DSCR10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with DSCR10: view

Phenotypes for DSCR10 Gene

GenomeRNAi human phenotypes for DSCR10:
genes like me logo Genes that share phenotypes with DSCR10: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DSCR10 Gene

Localization for DSCR10 Gene

Gene Ontology (GO) - Cellular Components for DSCR10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with DSCR10: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for DSCR10 Gene

Pathways & Interactions for DSCR10 Gene

SuperPathways for DSCR10 Gene

No Data Available

Interacting Proteins for DSCR10 Gene

Selected Interacting proteins: P59022-DSC10_HUMAN for DSCR10 Gene via UniProtKB

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for DSCR10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with DSCR10: view

No data available for Pathways by source and SIGNOR curated interactions for DSCR10 Gene

Drugs & Compounds for DSCR10 Gene

No Compound Related Data Available

Transcripts for DSCR10 Gene

mRNA/cDNA for DSCR10 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DSCR10 Gene

Down syndrome critical region gene 10 (non-protein coding):
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for DSCR10 Gene

No ASD Table

Relevant External Links for DSCR10 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DSCR10 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DSCR10 Gene

mRNA differential expression in normal tissues according to GTEx for DSCR10 Gene

This gene is overexpressed in Testis (x51.6).

NURSA nuclear receptor signaling pathways regulating expression of DSCR10 Gene:


SOURCE GeneReport for Unigene cluster for DSCR10 Gene:


mRNA Expression by UniProt/SwissProt for DSCR10 Gene:

Tissue specificity: Expressed in placenta and testis.
genes like me logo Genes that share expression patterns with DSCR10: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DSCR10 Gene

Orthologs for DSCR10 Gene

Evolution for DSCR10 Gene

Gene Tree for DSCR10 (if available)
Gene Tree for DSCR10 (if available)

No data available for Orthologs for DSCR10 Gene

Paralogs for DSCR10 Gene

No data available for Paralogs for DSCR10 Gene

Variants for DSCR10 Gene

Sequence variations from dbSNP and Humsavar for DSCR10 Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type
rs1000436063 -- 38,205,762(+) GATTG(A/G)CAAGC upstream-variant-2KB
rs1000891752 -- 38,205,432(+) CCATA(G/T)ATTTT upstream-variant-2KB
rs1001280491 -- 38,205,689(+) ACTCA(C/T)TTTTC upstream-variant-2KB
rs1001513706 -- 38,204,845(+) CTGAG(C/T)TCTTT upstream-variant-2KB
rs1001948560 -- 38,205,874(+) AGAAC(A/C)CCTTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for DSCR10 Gene

Variant ID Type Subtype PubMed ID
nsv1058886 CNV gain 25217958
nsv1072602 CNV deletion 25765185
nsv1122042 CNV deletion 24896259

Relevant External Links for DSCR10 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for DSCR10 Gene

Disorders for DSCR10 Gene

MalaCards: The human disease database

(1) MalaCards diseases for DSCR10 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
down syndrome
  • complete trisomy 21 syndrome
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for DSCR10

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with DSCR10: view

No data available for UniProtKB/Swiss-Prot and Genatlas for DSCR10 Gene

Publications for DSCR10 Gene

  1. Identification of two novel primate-specific genes in DSCR. (PMID: 12168953) Takamatsu K. … Takeda T. (DNA Res. 2002) 2 3 4 64
  2. Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. (PMID: 20485444) Wang Y. … Huang W. (J. Hum. Genet. 2010) 3 46 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for DSCR10 Gene

Sources for DSCR10 Gene

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