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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DSCAML1 Gene

protein-coding   GIFtS: 53
GCID: GC11M117332

Down Syndrome Cell Adhesion Molecule Like 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Down Syndrome Cell Adhesion Molecule Like 11 2
Down Syndrome Cell Adhesion Molecule 22 3
KIAA11323 5
Down Syndrome Cell Adhesion Molecule-Like Protein 12
Downs Syndrome Cell Adhesion Molecule Like 12
DSCAM23

External Ids:    HGNC: 146561   Entrez Gene: 574532   Ensembl: ENSG000001771037   OMIM: 6117825   UniProtKB: Q8TD843   

Export aliases for DSCAML1 gene to outside databases

Previous GC identifers: GC11M119651 GC11M118810 GC11M116836 GC11M116803 GC11M113232


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for DSCAML1 Gene: 
DSCAML1 (Down syndrome cell adhesion molecule like 1) is a protein-coding gene. Diseases associated with DSCAML1 include down syndrome, and retinitis, and among its related super-pathways are Cell junction organization. GO annotations related to this gene include protein homodimerization activity. An important paralog of this gene is IGSF10.

UniProtKB/Swiss-Prot: DSCL1_HUMAN, Q8TD84
Function: Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific
neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance
for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to
maintain mosaic spacing between AII amacrine cells (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_033899.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DSCAML1 gene promoter:
         AREB6   PPAR-gamma1   HTF   Lmo2   PPAR-gamma2   ZIC2/Zic2   LCR-F1   ITF-2   Tal-1beta   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDSCAML1 promoter sequence
   Search SABiosciences Chromatin IP Primers for DSCAML1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DSCAML1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23   Ensembl cytogenetic band:  11q23.3   HGNC cytogenetic band: 11q22.2-q22.3

DSCAML1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DSCAML1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M117332:  view genomic region     (about GC identifiers)

Start:
117,298,489 bp from pter      End:
117,688,240 bp from pter
Size:
389,752 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DSCL1_HUMAN, Q8TD84 (See protein sequence)
Recommended Name: Down syndrome cell adhesion molecule-like protein 1 precursor  
Size: 2053 amino acids; 224463 Da
Subcellular location: Cell membrane; Single-pass type I membrane protein (Potential)
Sequence caution: Sequence=AAM09558.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAA86446.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
1 PDB 3D structure from and Proteopedia for DSCAML1:
1VA9 (3D)    
Secondary accessions: Q76MU9 Q8IZY3 Q8IZY4 Q8WXU7 Q9ULT7
Alternative splicing: 2 isoforms:  Q8TD84-1   Q8TD84-2   

Explore the universe of human proteins at neXtProt for DSCAML1: NX_Q8TD84

Explore proteomics data for DSCAML1 at MOPED 

DSCAML1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

DSCAML1 Protein Expression

REFSEQ proteins: NP_065744.2  
ENSEMBL proteins: 
 ENSP00000434335   ENSP00000315465   ENSP00000436387  
Reactome Protein details: Q8TD84
Human Recombinant Protein Products for DSCAML1: 
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Novus Biologicals DSCAML1 Protein
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for DSCAML1 

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005886plasma membrane TAS--
GO:0009986cell surface IDA11453658
GO:0016021integral to membrane IEA--

DSCAML1 for ontologies           About GeneDecksing



DSCAML1 Antibody Products: 
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Assay Products for DSCAML1: 
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Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for DSCAML1 
Cloud-Clone Corp. CLIAs for DSCAML1


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
FN3: Fibronectin type III domain containing
ISET: Immunoglobulin superfamily / I-set domain containing
IGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing

5/6 InterPro protein domains (see all 6):
 IPR003598 Ig_sub2
 IPR007110 Ig-like_dom
 IPR003599 Ig_sub
 IPR003961 Fibronectin_type3
 IPR013098 Ig_I-set

Graphical View of Domain Structure for InterPro Entry Q8TD84

ProtoNet protein and cluster: Q8TD84

1 Blocks protein domain: IPB013098 Immunoglobulin I-set

UniProtKB/Swiss-Prot: DSCL1_HUMAN, Q8TD84
Similarity: Contains 6 fibronectin type-III domains
Similarity: Contains 10 Ig-like C2-type (immunoglobulin-like) domains


DSCAML1 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: DSCL1_HUMAN, Q8TD84
Function: Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific
neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance
for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to
maintain mosaic spacing between AII amacrine cells (By similarity)

     Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005515protein binding ----
GO:0042803protein homodimerization activity IDA11453658
     
DSCAML1 for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for DSCAML1:
 Cells with protrusions 

     3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Dscaml1):
 mortality/aging  nervous system  vision/eye 

DSCAML1 for phenotypes           About GeneDecksing

Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for DSCAML1 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DSCAML1

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DSCAML1 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DSCAML1 

miRNA
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hsa-miR-579 hsa-miR-376b hsa-miR-25 hsa-miR-3921 hsa-miR-548m hsa-miR-92b hsa-miR-571 hsa-miR-92a
SwitchGear 3'UTR luciferase reporter plasmidDSCAML1 3' UTR sequence
Inhib. RNA
Products:
    
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Gene Editing
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Clone
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Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DSCAML1


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for DSCAML1 About                                                                                                See pathways by source

SuperPathContained pathways About
1Cell-cell junction organization
Cell-Cell communication0.64
2DSCAM interactions
DSCAM interactions

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways


2        Reactome Pathways for DSCAML1
    Cell-Cell communication
DSCAM interactions



DSCAML1 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DSCAML1

STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

5 Interacting proteins for DSCAML1 (Q8TD843 ENSP000003154654) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
PLCL2Q9UPR03, ENSP000004096374I2D: score=3 STRING: ENSP00000409637
MAGI2Q86UL83, ENSP000003461514I2D: score=2 STRING: ENSP00000346151
MAGI3Q5TCQ93, ENSP000003046044I2D: score=3 STRING: ENSP00000304604
DSCAMENSP000003833034STRING: ENSP00000383303
ABI2ENSP000002610174STRING: ENSP00000261017
About this table

Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001709cell fate determination NAS12051741
GO:0007156homophilic cell adhesion IDA11453658
GO:0007162negative regulation of cell adhesion IEA--
GO:0007409axonogenesis NAS11453658
GO:0007417central nervous system development NAS12051741

DSCAML1 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DSCAML1 (DSCL1)

Search CenterWatch for drugs/clinical trials and news about DSCAML1 / DSCL1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DSCAML1 gene: 
NM_020693.2  

Unigene Cluster for DSCAML1:

Down syndrome cell adhesion molecule like 1
Hs.659513  [show with all ESTs]
Unigene Representative Sequence: AF491813
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000527706 ENST00000321322(uc001prh.1 uc001pri.1) ENST00000525836

miRNA
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8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate DSCAML1 (see all 17):
hsa-miR-579 hsa-miR-376b hsa-miR-25 hsa-miR-3921 hsa-miR-548m hsa-miR-92b hsa-miR-571 hsa-miR-92a
SwitchGear 3'UTR luciferase reporter plasmidDSCAML1 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
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QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DSCAML1
Clone
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OriGene ORF clones in mouse, rat for DSCAML1
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GenScript: all cDNA clones in your preferred vector: DSCAML1 (NM_020693)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for DSCAML1
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DSCAML1
Primer
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OriGene qSTAR qPCR primer pairs in human, mouse for DSCAML1
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DSCAML1
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DSCAML1
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DSCAML1

Additional mRNA sequence: 

AB032958.2 AF304304.1 AF304305.1 AF334384.1 AF491813.1 AK025940.1 

6 DOTS entries:

DT.75134403  DT.97825929  DT.100748976  DT.95193172  DT.97840391  DT.97803583 

24/45 AceView cDNA sequences (see all 45):

AB032958 BU538544 BM717919 NM_020693 BM694015 AI498283 BU957614 BM665756 
AF491813 AF304305 BM982372 AF304304 CD106638 CD630336 BU537986 CD630338 
BF528580 CK819152 BM680182 BM726574 BM927220 AF334384 BG912843 BM127803 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DSCAML1 expression in normal human tissues (normalized intensities)      DSCAML1 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CGATTTTACT
DSCAML1 Expression
About this image


DSCAML1 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/3 selected tissues (see all 3) fully expand
 
 Brain (Nervous System)    fully expand to see all 2 entries
         Cerebral Cortex
         hippocampus   
 
 Epithelium (Respiratory System)
         bronchial epithelial cells   
 
 Testis (Reproductive System)

See DSCAML1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DSCAML1

SOURCE GeneReport for Unigene cluster: Hs.659513

UniProtKB/Swiss-Prot: DSCL1_HUMAN, Q8TD84
Tissue specificity: Detected in heart, liver, pancreas, skeletal muscle, kidney and in brain, in particular in the
amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra, thalamus and subthalamus

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QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DSCAML1
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DSCAML1

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for DSCAML1 gene from 5/12 species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Dscaml11 , 5 Down syndrome cell adhesion molecule like 11, 5 91.14(n)1
98.15(a)1
  9 (24.84 cM)5
1148731  NM_001081270.11  NP_001074739.11 
 454302935 
chicken
(Gallus gallus)
Aves DSCAML11 Down syndrome cell adhesion molecule like 1 84.73(n)
91.75(a)
  428249  XM_003642612.1  XP_003642660.1 
lizard
(Anolis carolinensis)
Reptilia DSCAML16
Uncharacterized protein
91(a)
1 ↔ 1
GL343521.1(435398-474697)
zebrafish
(Danio rerio)
Actinopterygii dscaml11 Down syndrome cell adhesion molecule like 1 76.07(n)
84.22(a)
  100002762  XM_001920025.2  XP_001920060.2 
fruit fly
(Drosophila melanogaster)
Insecta CG70603
Dscam21
Down syndrome cell adhesion molecule 21 34(a)
(best of 3)3
46.02(n)1
33.49(a)1
  66C43
387881  NM_168196.31  NP_729225.21 


ENSEMBL Gene Tree for DSCAML1 (if available)
TreeFam Gene Tree for DSCAML1 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for DSCAML1 gene
IGSF102  NCAM22  DSCAM2  ENSG000002154282  MXRA52  NCAM12  
2 SIMAP similar genes for DSCAML1 using alignment to 3 protein entries:     DSCL1_HUMAN (see all proteins):
DSCAM    MUSK

DSCAML1 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/8243 SNPs in DSCAML1 are shown (see all 8243)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0355134
A colorectal cancer sample4--see VAR_0355132 V I mis40--------
VAR_0355124
A colorectal cancer sample4--see VAR_0355122 V I mis40--------
rs598498541,2
C--113453086(+) TGTGT-/GTGTGTGTGT
/GTGTGTGTGTGT
ATTTT
1 -- int11NA 2
rs354762671,2
C--113561933(+) ACACA-/CACA  
  CACACA
ATTAT
1 -- int11Minor allele frequency- CACACACACA:0.00NA 2
rs1486204161,2
--117298226(+) CCTCCA/GTTTAC 1 -- ds50010--------
rs1896810681,2
--117298274(+) TGCACC/GAAGCC 1 -- ds50010--------
rs1930482021,2
--117298282(+) GCCACC/TGACCT 1 -- ds50010--------
rs1844742031,2
--117298300(+) CTTGCA/GGGCCC 1 -- ds50010--------
rs1420958991,2
--117298346(+) GCTAAC/TTGCAA 1 -- ds50010--------
rs116004631,2
C,H--117298372(+) AGAGCA/GCTGAG 1 -- ds50010--------

HapMap Linkage Disequilibrium report for DSCAML1 (117298489 - 117548489 bp, first 250kb of DSCAML1)

Structural Variations
     Database of Genomic Variants (DGV) 10/14 variations for DSCAML1 (see all 14):    About this table     
Variant IDTypeSubtypePubMed ID
esv2660899CNV Deletion23128226
esv1005765CNV Deletion20482838
dgv246e199CNV Deletion23128226
esv2657601CNV Deletion23128226
esv1008110CNV Deletion20482838
nsv508CNV Insertion18451855
nsv509CNV Insertion18451855
nsv527773CNV Loss19592680
nsv521775CNV Loss19592680
nsv519857CNV Loss19592680

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing DSCAML1
DNA2.0 Custom Variant and Variant Library Synthesis for DSCAML1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 611782    OMIM disorders: --

3 diseases for DSCAML1:    About MalaCards
down syndrome    retinitis    neuronitis


DSCAML1 for disorders           About GeneDecksing

Genetic Association Database (GAD): DSCAML1
Human Genome Epidemiology (HuGE) Navigator: DSCAML1 (3 documents)

Export disorders for DSCAML1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for DSCAML1 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with DSCAML1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Cloning and functional characterization of DSCAML1, a novel DSCAM- like cell adhesion molecule that mediates homophilic intercellular adhesion. (PubMed id 11453658)1, 2, 3 Agarwala K.L....Yamakawa K. (2001)
  2. Human Variation in Alcohol Response Is Influenced by Variation in Neuronal Signaling Genes. (PubMed id 20201926)1, 4 Joslyn G....White R.L. (2010)
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
  4. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. (PubMed id 18519826)1, 4 Uhl G.R....Lerman C. (2008)
  5. A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection. (PubMed id 19074352)1, 4 Pollin T.I....Shuldiner A.R. (2008)
  6. Mammalian DSCAMs: roles in the development of the spinal cord, cortex, and cerebellum? (PubMed id 12051741)1, 2 Barlow G.M.... Korenberg J.R. (2002)
  7. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
  8. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2 Hirosawa M.... Ohara O. (1999)
  9. Genome-wide association study of age at menarche in Af rican-American women. (PubMed id 23599027)1 Demerath E.W....Haiman C.A. (2013)
  10. DSCAM and DSCAML1 function in self-avoidance in multi ple cell types in the developing mouse retina. (PubMed id 19945391)1 Fuerst P.G....Burgess R.W. (2009)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 57453 HGNC: 14656 AceView: DSCAML1 Ensembl:ENSG00000177103 euGenes: HUgn57453
ECgene: DSCAML1 H-InvDB: DSCAML1

(According to HUGE)
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HUGE: KIAA1132

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for DSCAML1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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