Aliases for DSCAML1 Gene
External Ids for DSCAML1 Gene
Previous GeneCards Identifiers for DSCAML1 Gene
GeneCards Summary for DSCAML1 Gene
DSCAML1 (Down Syndrome Cell Adhesion Molecule Like 1) is a Protein Coding gene. Diseases associated with DSCAML1 include Down Syndrome. Among its related pathways are Cell junction organization. GO annotations related to this gene include protein homodimerization activity. An important paralog of this gene is DSCAM.
UniProtKB/Swiss-Prot for DSCAML1 Gene
Cell adhesion molecule that plays a role in neuronal self-avoidance (PubMed:11453658). Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells (By similarity). Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions (By similarity).